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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 327 of 2,219.
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    EudraCT Number: 2008-004496-22 Sponsor Protocol Number: 13273 Start Date*: 2008-11-13
    Sponsor Name:Bayer Health Care AG
    Full Title: Prospective non-randomized (pharmacoepidemiologic) cohort study (open-label, multicenter) to assess the magnitude of potential risk with the administration of Gadovist® in patients with moderate to...
    Medical condition: Patients with moderate to severe renal impairment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10038469 Renal impairment NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-004504-31 Sponsor Protocol Number: 0822-031 Start Date*: 2008-09-16
    Sponsor Name:Merck Sharp & DOhme (Sweden) AB
    Full Title: A Phase III Randomized, Placebo-Controlled Study to Evaluate the Effect of Odanacatib (MK-0822) on Bone Mineral Density (BMD) and Overall Safety, and to Estimate the Effect of Odanacatib (MK-0822) ...
    Medical condition: low BMD (bone mineral density)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10032364 Other osteoporosis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Prematurely Ended) FR (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003669-18 Sponsor Protocol Number: SVS/K/00604 Start Date*: 2006-11-15
    Sponsor Name:Seven Seas Limited
    Full Title: Efficacy an tolerability of a combinatzion of glucosamine sulphate and the tw omega-3 unsaturated fatty acids EPA and DHA in comparison to glucosamine sulphate in patients with ostearthritis
    Medical condition: Osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002319-16 Sponsor Protocol Number: Pr LEVY - PCa - CPRC 2006 Start Date*: 2007-09-07
    Sponsor Name:Centre Hospitalier Universitaire de Nancy
    Full Title: Modulation de la vasoréactivité dans le choc septique : impact de la protéine C recombinante
    Medical condition: sepsis : sont inclus les patients répondant aux critères conventionnels du choc septique qui intègrent ceux d’infection et d’infection sévère
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002334-11 Sponsor Protocol Number: 12014A Start Date*: 2009-03-13
    Sponsor Name:H. Lundbeck A/S
    Full Title: Nalmefene Efficacy Study I: Randomised, double-blind, placebo-controlled, parallel-group, efficacy study of 20 mg nalmefene, as needed use, in patients with alcohol dependence
    Medical condition: Alcohol dependence
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001594 Alcohol dependence syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SE (Completed) FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002359-18 Sponsor Protocol Number: PEDVAC Start Date*: 2008-04-23
    Sponsor Name:Swedish Institute for Infectious Disease Control
    Full Title: DNA vaccination in HIV-vertically infected children
    Medical condition: Pazienti con infezione verticale da HIV di eta' compresa tra 4 -16 anni di ambo i sessi.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053500 Human immunodeficiency virus transmission LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002556-41 Sponsor Protocol Number: TRX 1.0 Start Date*: 2008-02-07
    Sponsor Name:Trimed Biotech GmbH
    Full Title: A randomized, open-label, 2-arm, multicentre, Phase II study to evaluate the safety and efficacy of Trivax, a dendritic cell-based interleukin-12 secreting autologous cancer vaccine, in combination...
    Medical condition: Metastatic renal cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050513 Metastatic renal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002557-23 Sponsor Protocol Number: ATH001-CLN01 Start Date*: 2007-11-02
    Sponsor Name:Advancell Advanced In Vitro Cell Technologies, S.A
    Full Title: A Phase I/II Open-Label Dose Escalation Study to Investigate the Safety and Tolerability of Acadesine in Patients with B-Cell Chronic Lymphocytic Leukaemia
    Medical condition: Patients with B-Cell Chronic Lymphocytic Leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003892 B-cell chronic lymphocytic leukaemia/prolymphocytic leukaemia/small lymphocytic lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007538-21 Sponsor Protocol Number: CYR-101C01 Start Date*: 2008-04-22
    Sponsor Name:CYRENAIC
    Full Title: A Multi-center, Inpatient and ambulatory, Phase 2, Double-blind, Randomised, Placebo-controlled Proof of Concept Study of CYR-101 in Patients with DSM-IV Schizophrenia
    Medical condition: Diagnosis of Schizophrenia in Male or female patients, as defined in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revised (DSM-IV TR, APA 2000) and confirmed by the St...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039626 Schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007555-14 Sponsor Protocol Number: C10953/2032/DP/US Start Date*: 2008-08-15
    Sponsor Name:Cephalon, Inc.
    Full Title: An 8-Week, Double-Blind, Placebo-Controlled, Parallel-Group, Fixed-Dosage Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/day) as Adjunctive Therapy in Adults With Major ...
    Medical condition: Major Depression Associated With Bipolar I Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057840 Major depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-004309-27 Sponsor Protocol Number: P04579 Start Date*: 2005-12-28
    Sponsor Name:Schering Plough Research Institute
    Full Title: Cross-Over Study of the Decongestant Effect of Phenylephrine Compared With Placebo and Pseudoephedrine as Active Control in SAR Subjects Exposed to Pollen in the Vienna Challenge Chamber
    Medical condition: Seasonal Allergic Rhinitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002724-29 Sponsor Protocol Number: RC 48/07 Start Date*: 2011-10-26
    Sponsor Name:ISTITUTO PER L'INFANZIA BURLO GAROFOLO
    Full Title: Continuous peritoneal infusion of ropivacaine following laparoscopy for postoperative analgesia in children: a randomized, double-blind, placebo-controlled study.
    Medical condition: Children aged over 1 year, undergoing elective abdominal laparoscopic surgery.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023693 Laparoscopy LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004699-38 Sponsor Protocol Number: RCCC10 Start Date*: Information not available in EudraCT
    Sponsor Name:Klinikum der Universität Regensburg
    Full Title: A prospective phase I/II, one-arm, multi-center, open label study of pioglitazone in combination with sorafenib and low dose IFN alpha in metastatic, non-resectable renal clear cell carcinoma
    Medical condition: To investigate the effect of an anti-inflammatory therapy consisting of pioglitazone (Actos) in combination with an angiostatic treatment with sorafenib (Nexavar) and Interferin-Alpha (Roferon) on ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038416 Renal clear cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004165-26 Sponsor Protocol Number: CA180-210 Start Date*: 2008-10-22
    Sponsor Name:FONDAZIONE NEOPLASIE SANGUE ONLUS
    Full Title: A MULTICENTER, OPEN-LABEL, PHASE II STUDY OF DASATINIB IN COMBINATION WITH MELPHALAN AND PREDNISONE (D-MP) IN ADVANCED, RELAPSED / REFRACTORY MULTIPLE MYELOMA PATIENTS.
    Medical condition: RELAPSED / REFRACTORY MULTIPLE MYELOMA PATIENTS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-003371-53 Sponsor Protocol Number: STROKE-FNUSA-01 Start Date*: 2008-08-08
    Sponsor Name:Fakultní nemocnice u svaté Anny
    Full Title: Acute Stroke Study of Optimized tPA Dosing in Correlation with Artery Status
    Medical condition: Patients with acute ischemic stroke with proven occlusion of major brain arteries demonstrated by transcranial ultrasound.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059620 Plasminogen activator inhibitor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004143-30 Sponsor Protocol Number: CQAB149B2311 Start Date*: 2008-01-22
    Sponsor Name:Novartis Farmaceutica S.A.
    Full Title: Estudio fase III, multicéntrico, aleatorizado, doble ciego, controlado con placebo, de 2 periodos cruzados, para evaluar el efecto de indacaterol (300 µg o.d.) en pacientes con enfermedad pulmonar ...
    Medical condition: Enfermedad Pulmonar Obstructiva Crónica (EPOC) de moderada a crónica
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) BE (Completed) DK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001431-58 Sponsor Protocol Number: ROX-2007-01 Start Date*: 2007-09-10
    Sponsor Name:ROXRO PHARMA, Inc.
    Full Title: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study of the Safety, Tolerability, and Analgesic Efficacy of Ketorolac Tromethamine Administered Intranasally for the Acute Treatment of Mig...
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027599 Migraine LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005615-26 Sponsor Protocol Number: P05365 Start Date*: 2008-05-30
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: Safety of SCH 527123 in Subjects with Neutrophilic Asthma
    Medical condition: Neutrophilic Asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GR (Completed) GB (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005620-32 Sponsor Protocol Number: 2006-56-DPI-1 Start Date*: 2009-05-08
    Sponsor Name:HEXAL AG
    Full Title: Efficacy and safety of Salmeterol/Fluticasone DPI HEXAL versus Seretide™ Accuhaler™ in adolescent and adult patients with moderate-to-severe persistent asthma: A 12-week, multicenter, randomized, d...
    Medical condition: moderate-to-severe persistent asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003555 Asthma bronchial LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2007-005628-34 Sponsor Protocol Number: P070145 Start Date*: 2008-09-12
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Etude de phase II d’identification de biomarqueurs de réponse au sunitinib chez des patients atteints d’une tumeur neuroendocrine peu différenciée avancée inopérable.
    Medical condition: Tumeurs Neuro-Endocrines (TNE) digestives
    Disease: Version SOC Term Classification Code Term Level
    8.1 10014713 Tumeurs Neuro-Endocrines (TNE) PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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