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Clinical trials for Heart Failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,476 result(s) found for: Heart Failure. Displaying page 4 of 74.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2019-004670-25 Sponsor Protocol Number: CQ-001-19 Start Date*: 2022-11-16
    Sponsor Name:Corequest sagl
    Full Title: Peritoneal Ultrafiltration in cardio Renal syndrome to prevent heart failure Exacerbation: The PURE Study
    Medical condition: Congestive Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.1 10007541 - Cardiac disorders 10007559 Cardiac failure congestive PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-005721-30 Sponsor Protocol Number: 161HF201 Start Date*: 2009-10-26
    Sponsor Name:Biogen Idec
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Tolerability of Oral Tonapofylline in Patients with Heart Failure and Renal Insufficiency
    Medical condition: Heart Failure and Renal Insufficiency.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038474 Renal insufficiency LLT
    9.1 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-005077-39 Sponsor Protocol Number: BBLOQ-2017 Start Date*: 2018-06-12
    Sponsor Name:Instituto de Investigación Sanitaria INCLIVA
    Full Title: Betablockers Withdrawal in Patients with Heart Failure with Preserved Ejection Fraction and Chronotropic Incompetence: Effect on Functional Capacity and life quality
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015958-38 Sponsor Protocol Number: TORLASCO Start Date*: 2009-09-30
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Effect of xantina oxidasi inhibition on left ventricular function and on energetic stores of the haert in patients affected by chronic cardiac insufficiency.
    Medical condition: patients affected by cardiac insufficiency
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007554 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002150-12 Sponsor Protocol Number: DANSVIGT Start Date*: 2017-10-11
    Sponsor Name:Danish Society of Cardiology, Heart Failure Working Group
    Full Title: DanHeart (H-HeFT / Met-HeFT)
    Medical condition: Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-000319-27 Sponsor Protocol Number: ALT-711-0527 Start Date*: 2007-07-02
    Sponsor Name:Alteon, Inc.
    Full Title: A Double-blind, Placebo-Controlled, Randomized Trial Evaluating the Efficacy and Safety of Alagebrium (ALT-711) in Patients with Chronic Heart Failure
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001254-17 Sponsor Protocol Number: CLCZ696B2320 Start Date*: 2016-09-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomized, double-blind, active-controlled study to evaluate the effects of LCZ696 compared to valsartan on cognitive function in patients with chronic heart failure and preserved e...
    Medical condition: Heart Failure with preserved ejection fraction (HF-pEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) LT (Completed) DE (Completed) ES (Completed) BG (Completed) NL (Completed) PL (Completed) BE (Completed) HR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003111-28 Sponsor Protocol Number: REPO-HFpEF-II Start Date*: 2023-02-15
    Sponsor Name:Hospital Clínico Universitario de Valencia
    Full Title: Mechanism-based drug REpurPOsing in a subtype of Heart Failure with Preserved Ejection Fraction (REPO-HFPEF)
    Medical condition: Subtype of Heart Failure with Preserved Ejection Fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003314-37 Sponsor Protocol Number: CCM1862 Start Date*: 2023-04-19
    Sponsor Name:CENTRO CARDIOLOGICO SPA FONDAZIONE MONZINO
    Full Title: Effects of combined diuretic therapy on exercise capacity, alveolus-capillary diffusion, and maintenance of euvolemia in chronic congestive heart failure, diuretic therapy compared between loop diu...
    Medical condition: congestive heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-001623-39 Sponsor Protocol Number: Levo1010 Start Date*: 2018-07-26
    Sponsor Name:Verein zur Förderung der Forschung auf dem Gebiet der Arteriosklerose, Thrombose und vaskulären Biologie (ATVB)
    Full Title: Assessment of body composition changes after Levosimendan treatment in patients with advanced heart failure
    Medical condition: Advanced heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000158-21 Sponsor Protocol Number: 740220 Start Date*: 2017-04-13
    Sponsor Name:Karolinska Institutet
    Full Title: Ferroglycine Sulfate Absorption in patients with Heart Failure and Iron Deficency: an interventional before and after study.
    Medical condition: Chronic Heart Failure with Iron Deficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10022977 Iron deficiency anemia, unspecified LLT
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002706-27 Sponsor Protocol Number: version 1.1 Start Date*: 2005-07-22
    Sponsor Name:Barts and the London NHS Trust, Department of Cardiology
    Full Title: Randomised Control Trial To Compare The Effects Of G-CSF And Autologous Bone Marrow Progenitor Cells Infusion On Quality Of Life And Left Ventricular Function In Patients With Heart Failure Seconda...
    Medical condition: Heart failure secondary to ischaemic heart disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-004488-20 Sponsor Protocol Number: FURO-HGUA-08/01 Start Date*: 2009-05-08
    Sponsor Name:HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE
    Full Title: Ensayo clínico en fase IV, multicéntrico, controlado, aleatorizado, para evaluar la eficacia y seguridad de 3 pautas de administración de furosemida en pacientes con descompensación aguda moderada-...
    Medical condition: Descompensación aguda moderada-severa en pacientes con insuficiencia cardíaca congestiva (Acute moderate to severe descompensation in patients with congestive heart failure)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003229-47 Sponsor Protocol Number: KEEP-ON Start Date*: 2022-01-12
    Sponsor Name:Instituto de Investigación Sanitaria INCLIVA
    Full Title: Phase III, multicenter, open-label, randomized clinical trial to evaluate efficacy of Sodium Zirconium Cyclosilicate (Lokelma) compared to standard of care to manage hyperkalemia in patients with c...
    Medical condition: Hyperkalemia in patients with chronic kidney disease (CKD) and heart failure history
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004861 10020647 Hyperkalemia LLT
    23.1 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    20.0 100000004849 10019285 Heart failure, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002321-74 Sponsor Protocol Number: 20061218 Start Date*: 2007-08-29
    Sponsor Name:Aarhus University Hospital, Skejby sygehus
    Full Title: Effect of 4 weeks treatment with Acipimox on left ventricular function, work capacity, insulin sensitivity and substrate metabolism in patients with chronic heart failure
    Medical condition: chronic stable heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000833-35 Sponsor Protocol Number: CRLX030A2201 Start Date*: 2011-10-24
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, phase II, double blind, randomized, parallel group, placebo-controlled study to evaluate the hemodynamic responses to intravenous RLX030 infusion in subjects with acute heart failure.
    Medical condition: Acute Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) IT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-000473-20 Sponsor Protocol Number: CLCZ696B3402 Start Date*: 2016-08-18
    Sponsor Name:Novartis Pharma services AG
    Full Title: A prospective evaluation of natriuretic peptide based referral of CHF patients in primary care
    Medical condition: Chronic heart failure with reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-003046-13 Sponsor Protocol Number: 2021/ABM/03/00008 Start Date*: 2023-11-27
    Sponsor Name:Śląskie Centrum Chorób Serca
    Full Title: Sacubitril/Valsartan in PriMAry preventIoN of the cardiotoxicity of systematic breaST canceR trEAtMent. Randomized, multicenter, double-blind, placebo-controlled study.
    Medical condition: Heart failure – post-anthracycline cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-001446-14 Sponsor Protocol Number: N/GF-TORAFIC-06 Start Date*: 2006-10-11
    Sponsor Name:NOVAG S.A., FERRER GRUPO
    Full Title: Multicenter parallel-group, concealed and randomized allocation and blinded-endpoint study, to evaluate the effects of Torasemide PR versus furosemide on a biochemical marker of collagen synthesis ...
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007582 Cardiac insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-001588-37 Sponsor Protocol Number: CRLX030A2202 Start Date*: 2011-11-29
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the renal hemodynamic effects of RLX030 at a dose of 30 μg/kg/day or placebo infused for 24 hours in su...
    Medical condition: Chronic heart failure with worsening of symptoms like shortness of breath at rest or minimal exertion
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) PL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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