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Clinical trials for Knee Arthroplasty

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    101 result(s) found for: Knee Arthroplasty. Displaying page 4 of 6.
    « Previous 1  2  3  4  5  6  Next»
    EudraCT Number: 2019-005010-19 Sponsor Protocol Number: HCB/2019/1148 Start Date*: 2020-08-21
    Sponsor Name:Hospital Clínic de Barcelona
    Full Title: Ultrasound-guided Genicular Nerve Block an Analgesic Alternative to LIA for Total Knee Arthroplasty. Randomized clinical trial.
    Medical condition: Total knee arthroplasty has become one of the most frequent surgical procedures in the world. Currently models employ high volume local infiltration analgesia (LIA) techniques. The genicular nerve ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-001457-26 Sponsor Protocol Number: A6171016 Start Date*: 2008-04-24
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A LONG-TERM, RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, PLACEBO-CONTROLLED, RADIOGRAPHIC STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF ORALLY ADMINISTERED SD-6010 IN SUBJECTS WITH SYMPTOMATIC OSTE...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-000242-17 Sponsor Protocol Number: Protocol_PPB_TKA_14012021 Start Date*: 2021-03-12
    Sponsor Name:Region Hospital Silkeborg
    Full Title: The effect of the popliteal plexus block on postoperative opioid consumption, pain, muscle strength and mobilization after total knee arthroplasty - a randomized, controlled, blinded study
    Medical condition: Postoperative pain following a total knee arthroplasty surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-003395-23 Sponsor Protocol Number: HK_VL_08_2014 Start Date*: 2015-01-20
    Sponsor Name:Section for Surgical Pathophysiology, Rigshospitalet
    Full Title: Effect of preoperative intravenous highdose methylprednisolone on quadriceps muscle function, endothelial function, complement activation and glucose homeostasis in patients scheduled for total kne...
    Medical condition: Knee joint arthrosis
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004143-21 Sponsor Protocol Number: OA-orMSCp-01 Start Date*: Information not available in EudraCT
    Sponsor Name:Bioinova, a.s.
    Full Title: Efficacy of autologous bone marrow-derived mesenchymal stem cells seeded on a 3D scaffold in treatment of knee cartilage defects. A randomized, controlled, open-label, multi-centre clinical trial.
    Medical condition: Knee Cartilage Defect
    Disease: Version SOC Term Classification Code Term Level
    27.0 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    21.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    20.0 10042613 - Surgical and medical procedures 10057104 Cartilage repair LLT
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10072638 Articular cartilage defect LLT
    20.0 10042613 - Surgical and medical procedures 10052913 Cartilage operation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-002744-40 Sponsor Protocol Number: HK_EA_02_2014 Start Date*: 2014-09-23
    Sponsor Name:Section For Surgical Pathophysiology, Rigshospitalet
    Full Title: Preoperative intraarticular injection of methylprednisolone, in patients scheduled for total knee-arthroplasty
    Medical condition: Knee joint arthrosis with hyperalgesia and severe movement related pain
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013817-93 Sponsor Protocol Number: 2190 Start Date*: 2009-08-27
    Sponsor Name:North Bristol NHS Trust, Research and Development
    Full Title: Arthroplasty Pain Experience Study (APEX): A randomised controlled trial to determine if local wound infiltration reduces chronic pain after lower limb arthroplasty.
    Medical condition: hip and knee osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005494-29 Sponsor Protocol Number: 1603 Start Date*: Information not available in EudraCT
    Sponsor Name:Ullevål University Hospital
    Full Title: Rifampin combination therapy versus monotherapy in early staphylococcal infections after total hip and knee arthroplasty
    Medical condition: Joint prosthesis infection after total hip and knee arthroplasty.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005642-22 Sponsor Protocol Number: SM3-PJ-14 Start Date*: 2015-03-06
    Sponsor Name:Pia Jæger
    Full Title: Adductor canal block with continuous infusion versus intermittent boluses and morphine consumption: A randomized, triple-masked, controlled study
    Medical condition: Primary total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-017804-95 Sponsor Protocol Number: ATRHEMOS/1 Start Date*: 2010-03-05
    Sponsor Name:Fundació Institut de Recerca de l?Hospital de la Santa Creu i Sant Pau
    Full Title: Prevención del sangrado postoperatorio: Ensayo clínico unicéntrico, aleatorizado, paralelo y controlado que evalúa la eficacia de la cola de fibrina y el ácido tranexámico en pacientes intervenidos...
    Medical condition: Pacientes que precisan de una artroplastia de rodilla. Patients with are needed of an arthroplasty of the knee.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016957-17 Sponsor Protocol Number: OXN4505 Start Date*: 2010-02-03
    Sponsor Name:Mundipharma Oy
    Full Title: A randomised, double-blind, parallel group multicenter study to demonstrate non-inferiority of the analgesic efficacy of oxycodone/naloxone 10/5 or 20/10 mg prolonged release tablets (OXN PR) BID c...
    Medical condition: postoperative pain after knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036236 Postoperative pain relief LLT
    12.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2016-005069-30 Sponsor Protocol Number: UG1_2016 Start Date*: 2017-02-28
    Sponsor Name:Pia Jæger
    Full Title: Comparison of the analgesic effect of an adductor canal block using a new suture-method catheter vs a standard perineural catheter vs a single bolus: A randomized, blinded, controlled study
    Medical condition: Primary total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-003122-88 Sponsor Protocol Number: SELK2-00005 Start Date*: 2019-01-21
    Sponsor Name:Tetherex Pharmaceuticals Corporation
    Full Title: A Phase 2, Randomized, Active Comparator-Controlled, Open-Label, Adaptive Design Study to Assess the Safety and Efficacy of Intravenously-Administered SelK2 in Patients Undergoing Total Knee Arthro...
    Medical condition: Venous thromboembolism occurring in patients undergoing total knee replacement arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10051055 Deep vein thrombosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: LV (Completed) BG (Completed) LT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-013329-41 Sponsor Protocol Number: A4091030 Start Date*: 2010-01-12
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: ESTUDIO EN FASE III, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO Y OXICODONA PARA DETERMINAR LA EFICACIA Y LA SEGURIDAD DE TANEZUMAB EN PACIENTES CON ARTROSIS DE RODILLA O CAD...
    Medical condition: ARTROSIS DE RODILLA Y CADERA osteoarthritis of the knee and hip
    Disease: Version SOC Term Classification Code Term Level
    12.0 10020108 Hips osteoarthritis LLT
    12.0 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) SE (Completed) DE (Completed) AT (Completed) DK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-002681-31 Sponsor Protocol Number: BAY1213790/17664 Start Date*: 2017-07-13
    Sponsor Name:Bayer AG
    Full Title: A randomized, active-comparator-controlled, multicenter study to assess the safety and efficacy of different doses of BAY 1213790 for the prevention of venous thromboembolism in patients undergoing...
    Medical condition: Prevention of venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) LT (Completed) CZ (Completed) DE (Completed) LV (Completed) BG (Completed) PL (Completed) GR (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2013-004313-41 Sponsor Protocol Number: 47659 Start Date*: 2014-05-19
    Sponsor Name:UMCG
    Full Title: Effect of pre-operative pain treatment by means of duloxetine on postoperative outcome after total hip or knee arthroplasty
    Medical condition: Osteoarthritis (knee or hip)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000610-39 Sponsor Protocol Number: ITI101711 Start Date*: 2005-12-15
    Sponsor Name:GlaxoSmithKline Research and Development Ltd.
    Full Title: A Dose Ranging Trial for the Evaluation of the Safety, Tolerability and Efficacy of Odiparcil in the Prevention of Venous Thromboembolism following Total Knee Replacement Surgery.
    Medical condition: Venous Thromboembolism
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) LT (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2011-004989-16 Sponsor Protocol Number: AGO/2011/011 Start Date*: 2012-03-27
    Sponsor Name:Ghent University Hospital
    Full Title: The effect of morphine and different local anesthetics on human chondrocytes: an in vivo study.
    Medical condition: Patients undergoing total knee arthroplasty.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10024760 Local anesthetic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002034-38 Sponsor Protocol Number: THL-04-11 Start Date*: 2011-06-15
    Sponsor Name:Rgshospitalet
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003009-10 Sponsor Protocol Number: PRG-BUP-03/02 Start Date*: 2005-08-05
    Sponsor Name:Barts and The London NHS Trust
    Full Title: A randomized, open label pilot study to investigate the effect of chronic administration of buprenorphine prior to arthroplasty on the opioid requirements of patients intraoperatively and postopera...
    Medical condition: Patients with severe chronic pain due to osteoarthritis of the knee or hip, awaiting surgical joint replacement surgery. ICD10: M16.50 & M17.30
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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