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The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    31,642 result(s) found for: 0. Displaying page 471 of 1,583.
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    EudraCT Number: 2010-022855-46 Sponsor Protocol Number: EWALL-PH-02 Start Date*: 2011-07-13
    Sponsor Name:Dekan des Fachbereichs Medizin der Goethe Universität, represented by the Coordinating Investigator
    Full Title: AN OPEN LABEL PHASE II STUDY TO EVALUATE THE EFFICACY AND SAFETY OF INDUCTION AND CONSOLIDATION THERAPY WITH NILOTINIB IN COMBINATION WITH CHEMOTHERAPY IN PATIENTS AGED 55 YEARS AND OVER WITH PHIL...
    Medical condition: Philadelphia chromosome positive Acute Lymphoblastic Leukemia in elderly Patients (55 years and older)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Prematurely Ended) ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-004977-10 Sponsor Protocol Number: 08meInnereA_GALACTIC Start Date*: 2013-07-25
    Sponsor Name:University Hospital Basel, Cardiology
    Full Title: Goal-directed Afterload Reduction in Acute Congestive Cardiac Decompensation Study
    Medical condition: - acute decompensated heart failure
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10054112 Hospitalisation PT
    19.0 10018065 - General disorders and administration site conditions 10011906 Death PT
    19.0 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prohibited by CA) BG (Completed)
    Trial results: View results
    EudraCT Number: 2007-001559-20 Sponsor Protocol Number: 95195608 Start Date*: 2007-04-17
    Sponsor Name:Cliniques Universitaires Saint-Luc
    Full Title: Steady-state pharmacokinetics of high dose acetaminophen inpost-op children. Rational use of N-acetyl cysteine for prevention of liver toxicity related to cumulative doses.
    Medical condition: Major surgery when the use of paracetamol is required for pain release
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001294-18 Sponsor Protocol Number: CS I-040302/01 Start Date*: 2007-09-06
    Sponsor Name:Kuros Biosurgery AG
    Full Title: A phase 2 randomised, open-label, multi-centre ascending dose study of the efficacy, safety and tolerability of I-040302 versus control injection (bone marrow aspirate or steroids) in children and ...
    Medical condition: Solitary Bone Cysts
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041309 Solitary bone cyst LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002150-31 Sponsor Protocol Number: 20090302 Start Date*: 2012-08-29
    Sponsor Name:Amgen Inc
    Full Title: An Open-label, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Darbepoetin alfa in Paediatric Subjects From Birth to Less than 1 Year of Age With A...
    Medical condition: Anaemia due to chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease LLT
    14.1 10005329 - Blood and lymphatic system disorders 10002272 Anemia LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019057-17 Sponsor Protocol Number: SPC3649-203 Start Date*: 2010-07-13
    Sponsor Name:Santaris Pharma A/S
    Full Title: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Ascending Multiple-Dose Study to Assess Safety, Tolerability, Pharmacokinetics and Antiviral Activity of SPC3649 (miravirsen) Administered ...
    Medical condition: Patients infected with chronic hepatitis C
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) SK (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000305-35 Sponsor Protocol Number: MKC-T1-102 Start Date*: 2006-06-23
    Sponsor Name:MannKind Corporation
    Full Title: A Prospective, Multi-Center, Open-Label, Randomized, Controlled Clinical Trial Comparing the Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial I...
    Medical condition: Diabetes mellitus type II
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001975-15 Sponsor Protocol Number: NL77514.078.21 Start Date*: 2022-07-26
    Sponsor Name:
    Full Title: The effect of extra hydration on kidney function during carboplatinpemetrexed-pembrolizumab in patients with advanced non-small cell lung cancer.
    Medical condition: Patient with advanced non-small cell lung cancer receiving treatment with carboplatin-pemetrexed-pembrolizumab.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002042-36 Sponsor Protocol Number: CNTO148UCO2001 Start Date*: 2014-07-10
    Sponsor Name:Janssen Biologics B.V.
    Full Title: A Phase 2a Open-label Study to Evaluate Prediction of Response to Golimumab Using a Transcriptomic Profile in Subjects with Moderately to Severely Active Ulcerative Colitis
    Medical condition: Moderately to Severely Active Ulcerative Colitis
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) CZ (Completed) BG (Completed) PL (Completed) DE (Completed) NL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-003111-22 Sponsor Protocol Number: V98_21 Start Date*: 2014-11-06
    Sponsor Name:GlaxoSmithKline Biologicals S.A.
    Full Title: A Phase II, Randomized, Comparative, Observer-Blind, Multi-Center Study Evaluating the Safety and Immunogenicity of the Liquid Formulation of Group B Streptococcus Trivalent Vaccine and of the Lyop...
    Medical condition: Healthy person immune response to Group B Streptococcus polysaccharide capsule antigens
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10053588 Group B streptococcus neonatal sepsis PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2011-001245-32 Sponsor Protocol Number: PGX-III-AP-002 Start Date*: 2011-10-19
    Sponsor Name:Forest Laboratories, Inc.
    Full Title: A Phase 3, Randomized, Double-Blind Trial of Apadenoson for the Detection of Myocardial Perfusion Defects Using Single-Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)
    Medical condition: Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001308-40 Sponsor Protocol Number: INHIXACOVID19 Start Date*: 2020-05-04
    Sponsor Name:ALMA MATER STUDIORUM UNIVERSITà DI BOLOGNA
    Full Title: Intermediate dose enoxaparin in hospitalized patients with moderate-severe COVID-19: a pilot phase II single-arm study, INHIXACOVID19
    Medical condition: Hospitalized adult patients with microbiologically confirmed moderate-severe COVID-19 infection
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10021881 Infections and infestations SOC
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10038738 Respiratory, thoracic and mediastinal disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002999-83 Sponsor Protocol Number: UmUDURONORR1 Start Date*: 2015-01-21
    Sponsor Name:Johan Styrke
    Full Title: Ciprofloxacin vs Trimetoprim/Sulfametoxazol for transrectal prostate biopsy - a randomized double blind phaze IV multicentre clinical trial
    Medical condition: Prophylaxis of bacterial infektions of the prostate following transrectal prostate biopsy
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-001343-44 Sponsor Protocol Number: IB-0319-002 Start Date*: 2019-05-21
    Sponsor Name:Instituto Bernabeu
    Full Title: Conventional ovarian stimulation vs. stimulation with single injection of Corifollitropin alfa in oocyte donors. Randomized clinical trial. Tail Studio
    Medical condition: Oocyte donation
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-003986-42 Sponsor Protocol Number: Rifa1 Start Date*: 2008-06-18
    Sponsor Name:University Hospital of Tübingen
    Full Title: Prospective, randomised, placebo controlled, double blind monocenter trial for the prophylactic treatment of diarrhoea with rifaximin for travellers to South- and Southeast-Asia
    Medical condition: diarrhoea of travellers to South- and Southeast-Asia
    Disease: Version SOC Term Classification Code Term Level
    12.0 10021907 Infectious diarrhea LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-004676-35 Sponsor Protocol Number: RVT-1401-2001 Start Date*: 2019-10-23
    Sponsor Name:Immunovant Sciences GmbH
    Full Title: ASCEND GO2: A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled Study of RVT-1401 for the Treatment of Patients with Active, Moderate to Severe Graves’ Ophthalmopathy
    Medical condition: Graves´Ophthalmopathy
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004853 10057889 Graves' ophthalmopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003024-46 Sponsor Protocol Number: Repha_1412 Start Date*: 2014-09-19
    Sponsor Name:Repha GmbH
    Full Title: Efficacy, safety and tolerability of Angocin Anti-Infekt N versus Placebo for MRSA eradication
    Medical condition: MRSA colonisation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10004017 Bacterial disease carrier PT
    20.0 10021881 - Infections and infestations 10068296 MRSA colonisation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004734-17 Sponsor Protocol Number: MV21118 Start Date*: 2007-10-30
    Sponsor Name:Terho Heikkinen
    Full Title: A double-blind, randomized, placebo-controlled study of early oseltamivir treatment of influenza in children 1-3 years of age
    Medical condition: Influenza
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022000 Influenza LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002634-20 Sponsor Protocol Number: NBF_HK_01_2018 Start Date*: 2018-10-23
    Sponsor Name:Anaesthesia Department, Hvidovre Hospital, Capital Region of Denmark
    Full Title: Highdose steroid for total knee arthroplasty - A randomized doubleblindet controlled trial.
    Medical condition: Perioperative management of total knee-arthroplasty because of knee-osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-002636-25 Sponsor Protocol Number: NBF_HK_03_2018 Start Date*: 2018-10-23
    Sponsor Name:Anaesthesia Department, Hvidovre Hospital, Capital Region of Denmark.
    Full Title: Highdose Steroid for High Pain Responders undergoing Total Hip-arthroplasty - A randomized doubleblindet controlled trial.
    Medical condition: Perioperative management of total hip-arthroplasty because of hip-osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10020096 Hip arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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