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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 570 of 2,220.
    EudraCT Number: 2015-001096-43 Sponsor Protocol Number: PHRN14-AM/PERFORMUS Start Date*: 2015-07-10
    Sponsor Name:CHRU de Tours
    Full Title: Treatment of superficial voluminous complicated slow-flow vascular malformations with sirolimus: a phase 2 trial in children observational-phase designed
    Medical condition: vascular malformations
    Disease: Version SOC Term Classification Code Term Level
    18.0 10010331 - Congenital, familial and genetic disorders 10074979 Vascular malformation PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001190-40 Sponsor Protocol Number: P110150 Start Date*: 2018-05-16
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 10019805 - Hepatobiliary disorders 10036206 Portal vein thrombosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004114-99 Sponsor Protocol Number: FERTIRES-2016 Start Date*: 2017-05-18
    Sponsor Name:AB-BIOTICS
    Full Title: USE OF P.N680S POLYMORPHISM TO CHOOSE THE EXOGEN FSH DOSE IN CONTROLLED OVARIAN HYPERSTIMULATION: A PROSPECTIVE TRIAL
    Medical condition: Infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-005199-90 Sponsor Protocol Number: RHB-104-04 Start Date*: 2019-02-14
    Sponsor Name:RedHill Biopharma Ltd.
    Full Title: An Open Label Study to Assess the Efficacy and Safety of Fixed-Dose Combination RHB-104 in Subjects with Active Crohn’s Disease Despite 26 Weeks of Participation in the MAP US RHB-104-01 Study
    Medical condition: Moderately to Severely Active Crohn's Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-001645-24 Sponsor Protocol Number: RECD3126 Start Date*: 2014-11-18
    Sponsor Name:Salix Pharmaceuticals, Inc.
    Full Title: A Double-Blind, Placebo-Controlled, Parallel-Group, Multicentre, Multiregional, One Year Study to Assess the Efficacy and Safety of Twice Daily Oral Rifaximin Delayed Release Tablets for Induction ...
    Medical condition: Treatment of active Crohn’s disease
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004856 10013099 Disease Crohns LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) CZ (Prematurely Ended) DE (Prematurely Ended) PL (Prematurely Ended) FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003672-47 Sponsor Protocol Number: CCD-01535BD1-01 Start Date*: 2016-12-20
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A single dose, randomised, double blind, double dummy, placebo controlled, 3-way crossover clinical study, comparing the onset of relief from methacholine-induced bronchoconstriction with CHF1535 1...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    19.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-004166-10 Sponsor Protocol Number: CO-338-085 Start Date*: 2018-05-04
    Sponsor Name:Clovis Oncology, Inc.
    Full Title: A Phase 2, Open-label Study of Rucaparib in Patients with Locally Advanced or Metastatic Urothelial Carcinoma
    Medical condition: Locally Advanced or Metastatic Urothelial Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10064467 Urothelial carcinoma LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10044412 Transitional cell carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended) ES (Prematurely Ended) DE (Completed) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-002176-83 Sponsor Protocol Number: SNP-S-01 Start Date*: 2015-04-01
    Sponsor Name:Clinirx Tangent Research
    Full Title: A randomized trial administering Sodium Nitroprusside vs. placebo as add-on to antipsychotics in patients with schizophrenia
    Medical condition: schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    17.1 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: RO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000436-15 Sponsor Protocol Number: DD-study-3 Start Date*: 2015-05-18
    Sponsor Name:Aarhus Universitet
    Full Title: Photodynamic diagnosis (PDD) in flexible cystoscopy – a randomized study with focus on significant recurrence
    Medical condition: Patients with non muscle invasive bladder cancer in their first year after the diagnosis.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004864 10005004 Bladder cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-002445-31 Sponsor Protocol Number: SIMBA-16 Start Date*: 2017-01-20
    Sponsor Name:Enrique de Madaria
    Full Title: SIMBA trial: Simvastatin in the Prevention of Recurrent Acute Pancreatitis, a Triple Blind Randomized Controlled Trial
    Medical condition: Recurrent acute pancreatitis (RAP)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10033647 Pancreatitis acute PT
    20.0 10017947 - Gastrointestinal disorders 10033657 Pancreatitis relapsing PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001876-31 Sponsor Protocol Number: SWAP Start Date*: 2016-10-26
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St Thomas NHS Foundation Trust
    Full Title: Feasibility of the safe withdrawal of inhaled corticosteroids in patients with mild to moderate COPD prescribed outside guidelines (SWAP)
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-002053-38 Sponsor Protocol Number: MITIGATE-NeoBOMB1 Start Date*: 2016-11-30
    Sponsor Name:Medical University Innsbruck
    Full Title: A Phase I/IIa study to evaluate safety, biodistribution, dosimetry and preliminary diagnostic performance of 68Ga-NeoBOMB1 in patients with advanced TKI-treated GIST using positron-emission tomogra...
    Medical condition: Gastrointestinal stromal tumours previously or currently under TKI-treatment including at least 50% TKI-resistant patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003452-75 Sponsor Protocol Number: PTG-100-02 Start Date*: 2017-02-20
    Sponsor Name:Protagonist Therapeutics, Inc
    Full Title: A PHASE 2B RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL ADAPTIVE 2-STAGE, MULTI-CENTRE STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ORAL PTG-100 INDUCTION IN SUBJECTS WITH MODERATE TO SEV...
    Medical condition: Moderate to Severe Active Ulcerative Colitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Prematurely Ended) HU (Prematurely Ended) BE (Completed) CZ (Prematurely Ended) NL (Prematurely Ended) PL (Prematurely Ended) HR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-005160-34 Sponsor Protocol Number: MV-1-2017 Start Date*: 2017-04-21
    Sponsor Name:Universitetsklinikken for Nyresygdomme og Blodtryksforhøjelse, Regionshospitalet Holstebro, Hospitalsenheden Vest
    Full Title: 18F-NaF PET/CT in combination with biomarkers for the classification of renal osteodystrophy in chronic kidney disease
    Medical condition: Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD), especially renal osteodystofi.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10065404 Combined positron emission tomogram and computerised tomogram LLT
    20.0 10022891 - Investigations 10022891 Investigations SOC
    20.0 100000004865 10066622 Chronic hemodialysis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002836-42 Sponsor Protocol Number: PRUEI Start Date*: 2017-06-22
    Sponsor Name:Asociación Instituto de Investigación Sanitaria BioCruces
    Full Title: Phase II Pilot Study to assess security, potential feasibility and effectiveness of treatment with platelet rich plasma in vascular ulcers iwth difficult healing in lower extremities.
    Medical condition: Ulcer that does not heal after being administered the optimal basic care after a period of six weeks.
    Disease: Version SOC Term Classification Code Term Level
    19.1 10040785 - Skin and subcutaneous tissue disorders 10050502 Neuropathic ulcer PT
    19.1 10040785 - Skin and subcutaneous tissue disorders 10012679 Diabetic neuropathic ulcer PT
    19.1 10040785 - Skin and subcutaneous tissue disorders 10040796 Skin and subcutaneous tissue ulcerations HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000066-34 Sponsor Protocol Number: VX15-809-112 Start Date*: 2016-06-24
    Sponsor Name:Vertex Pharmaceuticals Incorporated
    Full Title: A Phase 4, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design Study of the Effect of Lumacaftor/Ivacaftor Combination Therapy on Exercise Tolerance in Subjects Aged 12 Years and Older Wi...
    Medical condition: Cystic fibrosis in patients homozygous for the F508del-CFTR Mutation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10011762 Cystic fibrosis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002578-20 Sponsor Protocol Number: ESN364_HF_204 Start Date*: 2015-08-25
    Sponsor Name:Euroscreen S.A
    Full Title: Pilot/Phase IIa Trial to Investigate the Effect of ESN364 in Early Postmenopausal Women Suffering From Hot Flashes
    Medical condition: hot flashes
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004866 10020407 Hot flashes LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003356-51 Sponsor Protocol Number: ZEL001 Start Date*: 2015-10-15
    Sponsor Name:Zelmic AB
    Full Title: A single-centre, open-label, single-arm, Phase I/II study to investigate the effect of a hydrogen peroxide foam on clinical signs and symptoms and the vaginal flora in patients with bacterial vagin...
    Medical condition: Bacterial vaginosis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10004055 Bacterial vaginosis PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005161-12 Sponsor Protocol Number: OAS-12DOC-BIO Start Date*: 2015-10-22
    Sponsor Name:Oasmia Pharmaceutical AB
    Full Title: A multi-country, multicenter, randomized, open-label, parallel group study to assess the efficacy and safety of Docecal compared with Taxotere®
    Medical condition: adenocarcinoma of the breast
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10027475 Metastatic breast cancer LLT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10055113 Breast cancer metastatic PT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006198 Breast cancer recurrent PT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006187 Breast cancer PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: LV (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004012-37 Sponsor Protocol Number: HOM1-2015 Start Date*: 2015-12-18
    Sponsor Name:Ordination Dr. Hommer
    Full Title: An open, non-randomized study on the effect of changing from preserved prostaglandin formulations to preservative free tafluprost (Saflutan® Augentropfen) in patients with ocular hypertension or pr...
    Medical condition: Glaucoma / Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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