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Clinical trials for Fibrillation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    436 result(s) found for: Fibrillation. Displaying page 7 of 22.
    EudraCT Number: 2004-002013-36 Sponsor Protocol Number: ACA-SPAI-03-03 Start Date*: 2004-12-17
    Sponsor Name:CONCEPCION MORO SERRANO
    Full Title: A PROSPECTIVE DOUBLE BLIND AND RANDOMIZED STUDY ON THE EFFECT OF TRANDOLAPRIL, IN MAINTAINING SINUS RHYTHM IN PATIENTS WITH LONG-LASTING PERSISTENT ATRIAL FIBRILLATION. ESTUDIO PROSPECTIVO, DOBLE ...
    Medical condition: PACIENTES CON FA PERSISTENTE DE LARGA DURACÍON.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019442-87 Sponsor Protocol Number: DROPPAF Start Date*: 2010-07-02
    Sponsor Name:East Sussex NHS Trust
    Full Title: Dronedarone in pacemaker patients with paroxysmal atrial fibrillation
    Medical condition: Paroxysmal atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-003455-36 Sponsor Protocol Number: D3190C00005 Start Date*: 2007-12-21
    Sponsor Name:AstraZeneca AB
    Full Title: A Multi-centre, Double-blind, Randomised, Placebo-controlled, Single-dose, Phase II Study to Assess the Effects on Atrial and Ventricular Refractoriness and Haemodynamics of an Intravenous Infusion...
    Medical condition: AZD1305 is a novel antiarrhythmic agent being developed for treatment of atrial fibrillation (AF). Potential indications include conversion of AF to sinus rhythm (SR) and maintenance of SR after c...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) SE (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003069-25 Sponsor Protocol Number: DSE-EDO-01-16-EU Start Date*: 2017-02-08
    Sponsor Name:Daiichi Sankyo Europe GmbH
    Full Title: A Prospective, Randomized, Open-Label, Blinded Endpoint Evaluation (PROBE) Parallel Group Study Comparing Edoxaban vs. VKA in Subjects Undergoing Catheter Ablation of Non-valvular Atrial Fibrillati...
    Medical condition: Subjects undergoing catheter ablation of non-valvular atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed) GB (Completed) HU (Completed) ES (Completed) BE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002176-41 Sponsor Protocol Number: 17HH4268 Start Date*: 2019-09-03
    Sponsor Name:Imperial College of Science Technology and Medicine
    Full Title: PREvention of STroke in Intracerebral haemorrhaGE survivors with Atrial Fibrillation (PRESTIGE-AF)
    Medical condition: Ischaemic stroke prevention in patients with atrial fibrillation and previous intracerebral haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10003661 Atrial fibrillation paroxysmal LLT
    20.0 100000004849 10034039 Paroxysmal atrial fibrillation LLT
    20.0 100000004849 10066551 Chronic atrial fibrillation LLT
    20.0 100000004849 10071668 Permanent atrial fibrillation LLT
    22.1 100000004852 10057613 Thromboembolic stroke LLT
    21.1 100000004852 10022754 Intracerebral hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Ongoing) AT (Completed) FR (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001626-26 Sponsor Protocol Number: OMT28-C0201 Start Date*: 2019-01-23
    Sponsor Name:OMEICOS Therapeutics GmbH
    Full Title: A Placebo-controlled, double-blind, Randomized, dose finding phase II study on OMT-28 in MaIntenance of Sinus rhythm after Electrical cardioversion in patients with persistent Atrial Fibrillation (...
    Medical condition: Persistent atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BG (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-021258-20 Sponsor Protocol Number: EAST Start Date*: 2011-06-15
    Sponsor Name:Kompetenznetz Vorhofflimmern e.V. (AFNET)
    Full Title: Early treatment of Atrial fibrillation for Stroke prevention Trial (EAST)
    Medical condition: Atrial fibrillation, stroke, heart failure, myocardial infarction, cognitive dysfunction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    21.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    20.0 10037175 - Psychiatric disorders 10009841 Cognitive and attention disorders and disturbances HLGT
    20.0 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    21.1 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed) NL (Completed) CZ (Completed) BE (Completed) ES (Completed) PL (Completed) IT (Ongoing)
    Trial results: View results
    EudraCT Number: 2018-004202-25 Sponsor Protocol Number: PI18/01297 Start Date*: 2019-06-05
    Sponsor Name:Luis Nombela Franco
    Full Title: Usefulness of amiodarone for the Prevention of new onset Atrial Fibrillation after transcatheter aortic valve implantation: a randomized controlled trial
    Medical condition: atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001384-11 Sponsor Protocol Number: captaf Start Date*: 2008-04-03
    Sponsor Name:
    Full Title: Catheter Ablation compared with Pharmacological Therapy for Atrial Fibrillation – the CAPTAF trial
    Medical condition: To study the effect of catheter ablation (using CE marked products) on the quality of life an in patients with atrial fibrillation depsite treatment with conevntional antiarrhythmic medical therapy...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066664 Recurrent symptomatic atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001129-17 Sponsor Protocol Number: LDLL300.301 Start Date*: 2017-06-19
    Sponsor Name:AOP Orphan Pharmaceuticals GmbH
    Full Title: A multicenter, open-label study to investigate the effectiveness and safety of AOP Landiolol in controlling supraventricular tachycardia in pediatric patients (LANDI-PED).
    Medical condition: Supraventricular tachycardia in pediatric patients.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10074640 Junctional ectopic tachycardia PT
    20.0 10007541 - Cardiac disorders 10042604 Supraventricular tachycardia PT
    20.0 10007541 - Cardiac disorders 10003662 Atrial flutter PT
    20.0 10007541 - Cardiac disorders 10040752 Sinus tachycardia PT
    20.0 10007541 - Cardiac disorders 10003668 Atrial tachycardia PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed) DE (Ongoing) LT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2016-002105-18 Sponsor Protocol Number: 333336666666666699 Start Date*: 2017-05-04
    Sponsor Name:Helsinki City Hospital Haartman
    Full Title: Laboratory measurement of direct oral anticoagulants on patients with atrial fibrillation
    Medical condition: Non-valvular atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000833-38 Sponsor Protocol Number: ISIS329993-CS6 Start Date*: 2012-06-19
    Sponsor Name:Isis Pharmaceuticals, Inc.
    Full Title: A Phase 2 Study to Assess the Antiarrhythmic and Symptomatic Effect of the Second Generation Antisense Oligonucleotide ISIS 329993 Targeting CRP in Patients with Paroxysmal Atrial Fibrillation
    Medical condition: Atrial fibrillation (AF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003262-17 Sponsor Protocol Number: AG-1-2007. Start Date*: 2008-08-13
    Sponsor Name:University Hospital Magdeburg
    Full Title: Impact of irbesartan on oxidative stress and C-reactive protein levels in patients with persistent atrial fibrillation
    Medical condition: Blocking the angiotensin II type 1 receptor reduces systemic levels of oxidative stress markers and adhesion molecules compared to placebo in patients with persistent/permanent atrial fibrillation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001918-98 Sponsor Protocol Number: 31052015 Start Date*: 2016-01-12
    Sponsor Name:Vestre Viken HF
    Full Title: RATe control in Atrial Fibrillation II
    Medical condition: Permanent atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004595-13 Sponsor Protocol Number: BAY59-7939/11630 Start Date*: 2009-03-09
    Sponsor Name:Bayer HealthCare AG
    Full Title: A Prospective, Randomized, Double-Blind, Double-Dummy, Parallel-Group, Multicenter, Event-Driven, Non-inferiority Study Comparing the Efficacy and Safety of Once Daily Oral Rivaroxaban (BAY 59-7939...
    Medical condition: Prevention of Stroke and Non-CNS Systemic Embolism in Non-Valvular Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) NL (Completed) DK (Completed) BE (Completed) HU (Completed) SE (Completed) LT (Completed) GB (Completed) CZ (Completed) FR (Completed) BG (Completed) GR (Completed) AT (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-002516-33 Sponsor Protocol Number: NCT01420393 Start Date*: 2015-09-03
    Sponsor Name:University of Ottawa Heart Institute
    Full Title: A Randomized Ablation-based atrial Fibrillation rhythm control versus rate control Trial in patients with heart failure and high burden Atrial Fibrillation
    Medical condition: The study is comparing two accepted treatment methods (rhythm control-Catheter ablation with or without anti-arrhythmic drug control of maintaining sinus rhythm versus rate controls with medical th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001150-87 Sponsor Protocol Number: 150-CL-021 Start Date*: 2009-05-28
    Sponsor Name:Astellas Pharma Europe B.V.
    Full Title: A Phase 2, Double-Blind, Double-Dummy, Randomized, Parallel Group Dose Finding Study to Investigate the Safety and Tolerability of YM150 in Subjects with Non-Valvular Atrial Fibrillation and to Com...
    Medical condition: the prevention of stroke in patients with non-valvular atrial fibrillation (NVAF)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049165 Cerebrovascular accident prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) LV (Prematurely Ended) SK (Completed) DE (Completed) HU (Completed) FR (Completed) EE (Completed) ES (Completed) GB (Completed) CZ (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-000094-76 Sponsor Protocol Number: FLE-002 Start Date*: 2018-05-02
    Sponsor Name:InCarda Therapeutics, Inc.
    Full Title: A prospective, randomized, multicenter study of flecainide acetate oral inhalation solution in single and repeat dose regimens for acute conversion to sinus rhythm (SR) in subjects with recent onse...
    Medical condition: Acute conversion to sinus rhythm (SR) in subjects with recent onset of symptomatic paroxysmal atrial fibrillation (AF).
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10034039 Paroxysmal atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-002996-18 Sponsor Protocol Number: ATI-2042-CLN-08 Start Date*: 2005-03-10
    Sponsor Name:ARYx Therapeutics Limited
    Full Title: A Phase 2 Pilot Study of the Efficacy of ATI-2042 in subjects with Paroxysmal Atrial Fibrillation and Pacemakers
    Medical condition: Paroxysmal Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    7.0 10050106 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2022-001298-30 Sponsor Protocol Number: NL81102.100.22 Start Date*: 2022-07-28
    Sponsor Name:St. Antonius Hospital
    Full Title: What is the optimal antithrombotic strategy in patients with atrial fibrillation having acute coronary syndrome or undergoing percutaneous coronary intervention?
    Medical condition: Atrial fibrillation and coronary artery disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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