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Clinical trials for Heart Diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    2,578 result(s) found for: Heart Diseases. Displaying page 7 of 129.
    «« First « Previous 3  4  5  6  7  8  9  10  11  Next» Last»»
    EudraCT Number: 2014-004592-23 Sponsor Protocol Number: DLIFE Start Date*: 2015-03-12
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA
    Full Title: Phase IV randomized, double blind, placebo-controlled study: role of hypovitaminosis D in heart failure and possible advantages of cholecalciferol (Vit D) administration
    Medical condition: HEART FAILURE
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004849 10011949 Decompensation cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-001700-37 Sponsor Protocol Number: CELL-004 Start Date*: 2012-10-03
    Sponsor Name:Celladon Corporation
    Full Title: A Phase 2b, Double-Blind, Placebo-Controlled, Multinational, Multicenter, Randomized Study Evaluating the Safety and Efficacy of Intracoronary Administration of MYDICAR® (AAV1/SERCA2a) in Subjects ...
    Medical condition: Moderate to advanced heart failure (NYHA class II, III or IV) due to systolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004849 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) GB (Completed) BE (Completed) PL (Completed) NL (Completed) DK (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2018-001623-39 Sponsor Protocol Number: Levo1010 Start Date*: 2018-07-26
    Sponsor Name:Verein zur Förderung der Forschung auf dem Gebiet der Arteriosklerose, Thrombose und vaskulären Biologie (ATVB)
    Full Title: Assessment of body composition changes after Levosimendan treatment in patients with advanced heart failure
    Medical condition: Advanced heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000376-28 Sponsor Protocol Number: 1245.148 Start Date*: 2018-01-30
    Sponsor Name:Boehringer Ingelheim Limited
    Full Title: A randomised, double-blind, placebo-controlled, mechanistic cardiac magnetic resonance study to investigate the effects of empagliflozin treatment on cardiac physiology and metabolism in patients w...
    Medical condition: Chronic heart failure with reduced (HFrEF) and preserved ejection fraction (HFpEF) diagnosed at least 3 months prior to informed consent.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020376-37 Sponsor Protocol Number: CP120027.2001 Start Date*: 2011-02-11
    Sponsor Name:Trevena, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Adaptive, Ascending Dose-Titration Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Invasive Hemodynamics of TRV120027 in Patient...
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000803 Acute heart failure LLT
    14.1 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    14.1 10007541 - Cardiac disorders 10064081 Heart failure NYHA class III LLT
    14.1 10007541 - Cardiac disorders 10064082 Heart failure NYHA class IV LLT
    14.1 10007541 - Cardiac disorders 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004154-25 Sponsor Protocol Number: CLCZ696B2319E1 Start Date*: Information not available in EudraCT
    Sponsor Name:Novartis Pharma AG
    Full Title: A multicenter study to evaluate long-term safety and tolerability of open label sacubitril/valsartan in pediatric patients with heart failure due to systemic left ventricle systolic dysfunction wh...
    Medical condition: Pediatric heart failure : Patients (≥ 13 months) with HF due to systemic left ventricular systolic dysfunction. [Note: All patients per protocol for the core study CLCZ696B2319 (PANORAMA-HF) ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: PL (Completed) FR (Completed) BG (Completed) PT (Completed) CZ (Completed) ES (Ongoing) HU (Completed) HR (Completed) DE (Completed) AT (Completed) IT (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2009-016498-13 Sponsor Protocol Number: TIC-0911 Start Date*: 2010-12-22
    Sponsor Name:Fundación para la Formación en Investigación Sanitarias de la Región de Murcia
    Full Title: Estudio aleatorizado y doble-ciego para valorar el beneficio del tratamiento con testosterona en pacientes deficientes con IC avanzada (TIC)
    Medical condition: Deficiencia de testorena en varones con insuficiencia cardiaca.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003119-39 Sponsor Protocol Number: 38RC15.175 Start Date*: 2015-10-29
    Sponsor Name:Centre Hospitalier Universitaire de Grenoble
    Full Title: effects of a short therpay of zolpidem with support servo-ventilation versus placebo in patients with central sleep apnea with chronic heart failure
    Medical condition: chronic heart failure and central sleep apnea
    Disease: Version SOC Term Classification Code Term Level
    18.1 10038738 - Respiratory, thoracic and mediastinal disorders 10040979 Sleep apnoea syndrome PT
    18.1 100000004849 10019276 Heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001784-77 Sponsor Protocol Number: ML6721 Start Date*: 2012-05-07
    Sponsor Name:University Hospitals Leuven
    Full Title: Fontan patients: Comprehensive evaluation of the pulmonary circulation to identify pulmonary vascular disease and its influence on ventricular hemodynamics.
    Medical condition: Fontan patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10010495 Congenital heart disease NOS LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022529-14 Sponsor Protocol Number: WC25501 Start Date*: 2011-02-04
    Sponsor Name:F.Hoffmann-La Roche
    Full Title: A phase III, double-blind, randomized, placebo-controlled, multi-center study evaluating the efficacy and safety of dalcetrapib on lipids, lipoproteins, apolipoproteins and markers of CV risk in pa...
    Medical condition: Coronary Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10068617 Coronary heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) NL (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2020-004877-38 Sponsor Protocol Number: PREVENT-MINS Start Date*: 2021-06-18
    Sponsor Name:Uniwersytet Jagielloński - Collegium Medicum
    Full Title: Ivabradine for PREVENTion of Myocardial Injury after Noncardiac Surgery (MINS) - PREVENT-MINS Trial
    Medical condition: Myocardial Injury after Noncardiac Surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10028601 Myocardial ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-002522-23 Sponsor Protocol Number: BAY1067197/16782 Start Date*: 2013-12-20
    Sponsor Name:Bayer Healthcare AG
    Full Title: A double blinded, placebo controlled, study to investigate the safety, tolerability, pharmacokinetics and acute cardiovascular responses of a 7 day oral treatment with the partial adenosine A1 rece...
    Medical condition: Chronic systolic heart failure
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-000269-27 Sponsor Protocol Number: DSCK101 Start Date*: 2014-11-06
    Sponsor Name:German Foundation for Chronically Ill
    Full Title: Efficacy and tolerance of Beta Blocker and Procoralan uptitration in chronic heart failure patients under telemedical control: „70 bpm on day 28“
    Medical condition: Patients with chronic heart failure and resting heart rate of ≥ 75 bmp
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000220-33 Sponsor Protocol Number: CLCZ696BDE03 Start Date*: 2019-02-04
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A randomized, double-blind, active-controlled study to assess the effect of sacubitril/valsartan compared with enalapril to improve erectile function in patients with heart failure with reduced eje...
    Medical condition: Patients with heart failure with reduced ejection fraction (HFrEF) and erectile dysfunction (ED)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008502 CHF LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022821-14 Sponsor Protocol Number: 2010-022821-14 Start Date*: 2010-11-11
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: Cardiovascular Outcomes of Replacement with Testosterone. Role of testosterone replacement therapy in patients with heart failure.
    Medical condition: MALE HYPOGONADISM
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014698 SOC
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002912-25 Sponsor Protocol Number: 1VIT15043 Start Date*: 2019-11-18
    Sponsor Name:American Regent, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Injectafer® (Ferric Carboxymaltose) as Treatment for Heart Failure with Iron Deficiency
    Medical condition: Heart Failure with Iron Deficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10022974 Iron deficiency anemia LLT
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) HU (Completed) CZ (Completed) LT (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000413-48 Sponsor Protocol Number: 8.1(IRE),2017.03.24 Start Date*: 2015-07-01
    Sponsor Name:ACS Biomarker
    Full Title: Bioprofiling response to mineralocorticoid receptor antagonists for the prevention of heart failure. A proof of concept clinical trial within the EU FP 7 “HOMAGE” programme « Heart OMics in AGing
    Medical condition: Elderly patients with Clinical and Biological risk factors for developing heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) NL (Prematurely Ended) GB (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-003111-28 Sponsor Protocol Number: REPO-HFpEF-II Start Date*: 2023-02-15
    Sponsor Name:Hospital Clínico Universitario de Valencia
    Full Title: Mechanism-based drug REpurPOsing in a subtype of Heart Failure with Preserved Ejection Fraction (REPO-HFPEF)
    Medical condition: Subtype of Heart Failure with Preserved Ejection Fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015712-17 Sponsor Protocol Number: G080186 Start Date*: 2010-03-25
    Sponsor Name:HCRI
    Full Title: A prospective, multi-center, randomized, double-blind trial to assess the effectiveness and safety of 12 versus 30 months of dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous cor...
    Medical condition: Dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention (PCI) with either drug eluting stent (DES) or bara metal stent (BMS) placement for the treatment of corona...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10055218 Ischemic heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) HU (Completed) DE (Completed) CZ (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000486-37 Sponsor Protocol Number: CHF201701 Start Date*: 2019-03-27
    Sponsor Name:Heart Initiative
    Full Title: STRONG-HF: Safety, Tolerability and efficacy of Rapid Optimization, helped by NT-proBNP testing, of Heart Failure therapies
    Medical condition: Acute Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) HR (Completed)
    Trial results: View results
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