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Clinical trials for Shock

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    318 result(s) found for: Shock. Displaying page 7 of 16.
    EudraCT Number: 2009-017636-41 Sponsor Protocol Number: CRO1453 Start Date*: 2010-05-27
    Sponsor Name:Imperial College
    Full Title: Vasopressin and Corticosteroids in Septic Shock
    Medical condition: Septic shock - low blood pressure due to infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-001141-32 Sponsor Protocol Number: 09.0111p Start Date*: 2011-04-28
    Sponsor Name:Isala klinieken department Cardiology
    Full Title: Catheter ablation versus Amiodarone to pRevent Future ventricular tachycardia Episodes in patients with a defibrillator and a history of a myocardial infarction
    Medical condition: The primary purpose of this randomized study is the assessment of recurrences of sustained VT and ICD therapy for VT or VF after appropriate ICD therapy (ATP or shock) in patients with a history of...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-013115-35 Sponsor Protocol Number: MP4OX-09-TRA-204 Start Date*: 2009-11-05
    Sponsor Name:Sangart, Inc.
    Full Title: A multi-center, randomized, double-blind, controlled dose-finding study to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic ...
    Medical condition: Trauma with lactic acidosis due to hemorrhagic shock
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004430-15 Sponsor Protocol Number: GS-US-356-0101 Start Date*: 2014-10-07
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: A Phase 2, Double-Blind, Randomized, Placebo Controlled, Dose Ranging, Parallel Group Study to Evaluate the Effect of GS-6615 on Ventricular Arrhythmia in Subjects with Implantable Cardioverter-Def...
    Medical condition: Subjects with an ICD or CRT-D implanted for primary or secondary prevention
    Disease: Version SOC Term Classification Code Term Level
    17.1 10007541 - Cardiac disorders 10047281 Ventricular arrhythmia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) PL (Completed) DK (Completed) CZ (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-001219-44 Sponsor Protocol Number: 1123.28 Start Date*: 2008-01-30
    Sponsor Name:Boehringer Ingelheim France
    Full Title: STREAM - STrategic Reperfusion Early After Myocardial Infarction Comparison of the efficacy and safety of a strategy of pre-hospital fibrinolytic treatment with tenecteplase and additional antipla...
    Medical condition: ST-elevation myocardial infaction within 3 hours of onset of symptoms
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) AT (Completed) GB (Completed) IT (Completed) ES (Completed) BE (Completed) DE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2008-003281-25 Sponsor Protocol Number: ALBIOS STUDY Start Date*: 2008-04-17
    Sponsor Name:OSPEDALE MAGGIORE DI MILANO (IRCCS)
    Full Title: Efficacy of albumin administration for volume replacement in patients with severe sepsis or septic shock
    Medical condition: Patients with severe sepsis or septic shock
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021881 Infections and infestations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002650-67 Sponsor Protocol Number: IBERepic/2018 Start Date*: 2018-11-15
    Sponsor Name:Ibermutuamur (Mutua Colaboradora con la Seguridad Social nº 274)
    Full Title: Comparison of the efficacy of autologous platelet rich plasma injections, and extracorporeal shock wave therapy, in the treatment of work –related lateral epicondylitis.
    Medical condition: The epicondylitis is an overuse injury, in most cases, is a self-limited course and responds well to conservative treatment. Its etiology is degenerative and is related to a repetitive overuse and ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004401-10 Sponsor Protocol Number: HYPRESS Start Date*: 2008-01-15
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: Hydrocortisone for Prevention of Septic Shock Placebo-controlled, randomised, double-blind study to investigate the efficacy and safety of low dose hydrocortisone to prevent the development of se...
    Medical condition: Patients with severe sepsis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017350-13 Sponsor Protocol Number: TMFL01 Start Date*: 2009-11-20
    Sponsor Name:Erasme Hospital
    Full Title: Pharmacokinetics of oseltamivir in patients with infection due to influenza A H1N1 2009 admitted in intensive care unit.
    Medical condition: severe infection due to influenza A H1N1
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022002 Influenza A virus infection LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-000407-16 Sponsor Protocol Number: PI2018_843_0007 Start Date*: 2018-12-05
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Prospective multicenter randomized double-blind study comparing caspofungin to placebo for the treatment of ICU yeast intra-abdominal infection
    Medical condition: intraabdominal yeast infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-003551-22 Sponsor Protocol Number: 55029 Start Date*: 2016-12-28
    Sponsor Name:Erasmus MC - Sophia Children's Hospital
    Full Title: STATIC IV: Efficacy of a loading dose of intravenous salbutamol in patients admitted to a PICU for severe acute asthma
    Medical condition: Severe acute (viral) wheeze and severe acute asthma
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10047921 Wheeze LLT
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10041961 Status asthmaticus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001263-73 Sponsor Protocol Number: 30-01-2012_1 Start Date*: 2012-05-25
    Sponsor Name:UZ Leuven
    Full Title: Involvement of corticotrophin-releasing hormone (CRH) and mucosal mast cells in stress-induced changes in intestinal permeability in healthy volunteers.
    Medical condition: Stress-induced intestinal hyperpermeability
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10001039 Acute reaction to stress LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-004959-50 Sponsor Protocol Number: Heliox-AP Start Date*: 2016-05-29
    Sponsor Name:S.E. Carburos Metálicos S.A. grupo Air Products
    Full Title: HELIOX-DRIVEN BETA2-AGONISTS NEBULIZATION FOR CHILDREN WITH MODERATE TO SEVERE ACUTE ASTHMA: A RANDOMIZED CONTROLLED TRIAL
    Medical condition: Moderate to severe exacerbations of asthma
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10064823 Asthmatic crisis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-001713-20 Sponsor Protocol Number: ASTHMAFAST Start Date*: Information not available in EudraCT
    Sponsor Name:Centre Hospitalier Intercommunal de Créteil
    Full Title: Comparison of the efficacy and safety of budesonide/formoterol Turbuhaler® versus terbutaline nebulization as reliever therapy in children with asthma presenting at the emergency room for moderate ...
    Medical condition: moderate asthma exacerbation
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10049585 Infantile asthma LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10064823 Asthmatic crisis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-002300-12 Sponsor Protocol Number: EPOS_ZKSJ0134 Start Date*: 2021-12-20
    Sponsor Name:Friedrich Schiller University
    Full Title: Epirubicin for the Treatment of Sepsis & Septic Shock
    Medical condition: Patients with sepsis or septic shock, currently hospitalized at the Intensive Care Unit (ICU) or Intermediate Care (IMC) regardless where the sepsis was first diagnosed.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-002335-14 Sponsor Protocol Number: LAMBDA Start Date*: 2018-12-05
    Sponsor Name:AOU DI BOLOGNA POLICLINICO S.ORSOLA-MALPIGHI
    Full Title: A ß-d-glucan guided antifungal stewardship strategy for the management of patients with severe abdominal sepsis. A multicenter interventional explorative study with a pharmadynamic/pharmachokinetic...
    Medical condition: Patients with severe sepsis or septic shock
    Disease: Version SOC Term Classification Code Term Level
    23.1 10021881 - Infections and infestations 10066593 Post procedural sepsis PT
    20.0 10021881 - Infections and infestations 10058040 Abdominal sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002632-75 Sponsor Protocol Number: CLI-050000-04 Start Date*: 2020-07-08
    Sponsor Name:CHIESI FARMACEUTICI S.p.A
    Full Title: Multicenter, open-label, randomised trial to assess the efficacy and tolerability of poractant alfa (porcine surfactant, Curosurf®) in hospitalized patients with SARS-COV-19 acute respiratory distr...
    Medical condition: patients with SARS-COV-19 acute respiratory distress syndrome (ARDS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-002322-85 Sponsor Protocol Number: KAN0006 Start Date*: 2020-07-02
    Sponsor Name:Kancera AB
    Full Title: KAND567 Versus Placebo in Subjects Hospitalized with COVID-19. A Phase II, Randomized, 2-Arm Parallel-Group, Double-blind Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics.
    Medical condition: Acute respiratory distress syndrome (ARDS) in COVID-19 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001302-30 Sponsor Protocol Number: ACOVACT Start Date*: 2020-04-15
    Sponsor Name:Medical University of Vienna
    Full Title: A multicenter, randomized, active controlled, open label, platform trial on the efficacy and safety of experimental therapeutics for patients with COVID-19 (caused by infection with severe acute re...
    Medical condition: Infection with SARS-COV-2 (=COVID-19)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10021881 - Infections and infestations 10035737 Pneumonia viral PT
    21.1 100000004855 10003083 ARDS LLT
    20.0 10021881 - Infections and infestations 10038700 Respiratory infection LLT
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-005153-37 Sponsor Protocol Number: LJ501-CRH04 Start Date*: 2018-07-11
    Sponsor Name:La Jolla Pharmaceutical Company
    Full Title: A Randomised, Placebo-controlled, Double-blind, Multicentre Efficacy and Safety Study of LJPC-501 in Paediatric Patients > 2 to 17 Years of Age with Catecholamine-Resistant Hypotension Associated w...
    Medical condition: Catecholamine-resistant hypotension associated with distributive shock
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) EE (Completed) LT (Prematurely Ended) FR (Completed) ES (Temporarily Halted) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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