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Clinical trials for 1

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    39,321 result(s) found for: 1. Displaying page 717 of 1,967.
    EudraCT Number: 2013-004376-35 Sponsor Protocol Number: ISSBRILO176 Start Date*: 2014-01-14
    Sponsor Name:Hellenic Cardiovascular Research Society
    Full Title: A Single Center, Phase II, Assessor-Blinded, RaNdomized, Active Controlled, Parallel-Group Trial to COmpare Ticagrelor Versus Clopidogrel on the REduction of ArteriaL STiffness and Wave Reflections...
    Medical condition: Coronary Artery Disease (with an indication for coronary angiography)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2011-003743-22 Sponsor Protocol Number: D9422C00001 Start Date*: Information not available in EudraCT
    Sponsor Name:AstraZeneca AB
    Full Title: A Multicenter, Open label, Non-Comparative Study to Evaluate the Safety of Entocort EC for the Treatment of Crohn's Disease in Paediatric Subjects Aged 5 to 17 Years, Inclusive
    Medical condition: Crohn's Disease
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-003263-37 Sponsor Protocol Number: R668-AD-1412 Start Date*: 2015-02-11
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Phase 2A Study Investigating the Safety, Pharmacokinetics, Immunogenicity, and Exploratory Efficacy of Dupilumab in Patients Aged ≥6 to <18 Years With Atopic Dermatitis
    Medical condition: Atopic dermatits
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004858 10003639 Atopic dermatitis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) CZ (Completed) PL (Completed) GB (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-000831-41 Sponsor Protocol Number: AMAG-FER-IDA-304 Start Date*: 2016-06-09
    Sponsor Name:AMAG Pharmaceuticals, Inc.
    Full Title: A Phase III, Randomized, Multicenter, Double-Blind, Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA)
    Medical condition: Iron deficiency anemia (IDA)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004851 10022975 Iron deficiency anemia secondary to blood loss (chronic) LLT
    18.1 100000004851 10022976 Iron deficiency anemia secondary to inadequate dietary iron intake LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) LT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-004565-15 Sponsor Protocol Number: FE 999907 CS003 Start Date*: 2005-04-06
    Sponsor Name:Ferring BV
    Full Title: Pentasa® Once Daily In Ulcerative colitis for Maintenance of remission: PODIUM An International multi-centre investigator blinded randomised controlled study of Pentasa ® Sachet comparing one gra...
    Medical condition: Ulcerative collitis (UC)
    Disease: Version SOC Term Classification Code Term Level
    4.1 10009900 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) DK (Completed) SE (Completed) CZ (Completed) FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002404-34 Sponsor Protocol Number: F02695 LP 202 Start Date*: 2006-11-09
    Sponsor Name:Pierre Fabre Médicament
    Full Title: A DOUBLE BLIND, MULTINATIONAL, MULTICENTRE, PLACEBO-CONTROLLED 10-WEEK STUDY ASSESSING THE EFFICACY AND SAFETY OF F2695 SR FLEXIBLE DOSE (75,100 MG /DAY) IN THE TREATMENT OF PATIENTS WITH MAJOR DEP...
    Medical condition: Major Depressive Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Completed) DE (Completed) FI (Completed) CZ (Completed) SE (Completed) LV (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001788-21 Sponsor Protocol Number: RO-2455-302-RD Start Date*: 2014-04-11
    Sponsor Name:TAKEDA DEVELOPMENT CENTRE EUROPE LTD
    Full Title: A multicenter, randomized, double-blind phase 3 study to evaluate tolerability and pharmacokinetics of 500μg roflumilast once daily with an up-titration regimen in COPD, including an open-label do...
    Medical condition: chronic obstructive pulmonary disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SK (Completed) DE (Completed) HU (Completed) RO (Completed) GR (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2014-003242-28 Sponsor Protocol Number: D4280C00015 Start Date*: 2015-05-20
    Sponsor Name:AstraZeneca AB
    Full Title: A single blind, randomised, multi-centre, active controlled, trial to evaluate safety, tolerability, pharmacokinetics and efficacy of ceftazidime and avibactam when given in combination with metron...
    Medical condition: Complicated Intra-Abdominal Infection (cIAI)
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004862 10056570 Intra-abdominal infection LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) ES (Completed) CZ (Completed) GR (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2005-003733-40 Sponsor Protocol Number: CA183-002 Start Date*: 2007-03-30
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Multicenter, Randomized Double-Blind Phase II/III Study in the First-Line Treatment of Advanced Transitional Cell Carcinoma (TCC) of the Urothelium Comparing Vinflunine/Gemcitabine to Placebo/Gem...
    Medical condition: Locally advanced or metastatic Transitional Cell Carcinoma (TCC) of the urothelium
    Disease: Version SOC Term Classification Code Term Level
    8.1 10044412 Transitional cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed) ES (Completed) DK (Prematurely Ended) IT (Prematurely Ended) GR (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006370-25 Sponsor Protocol Number: IMA901-202 Start Date*: 2007-05-07
    Sponsor Name:immatics biotechnologies GmbH
    Full Title: Phase 2, randomised, open label, multicenter study of intradermal IMA901 plus GM-CSF with or without low dose cyclophosphamide pre-treatment in advanced renal cell carcinoma patients with measurabl...
    Medical condition: HLA-A*02-positive patients with advanced clear cell RCC who have progressed during or after first-line systemic therapy for advanced disease and have a favourable or intermediate risk after systemi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SK (Completed) GB (Completed) AT (Completed) HU (Completed) ES (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2004-000299-15 Sponsor Protocol Number: BC1-03 Start Date*: 2004-11-03
    Sponsor Name:Algeta AS
    Full Title: A double-blind, dose-response, phase II, multicentre study of radium-223 (Alpharadin TM ) for the palliation of painful bone metastases in hormone refractory prostate cancer patients
    Medical condition: The target population is patients suffering from bone pain due to skeletal metastasis secondary to prostate cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000451-13 Sponsor Protocol Number: 1201 Start Date*: 2012-10-16
    Sponsor Name:Transplant Institute, Sahlgrenska University Hospital
    Full Title: A controlled randomized, open-label, multi-centre study evaluating if a steroid-free immunosuppressive protocol, based on single dose ATG-induction, low tacrolimus-dose and therapeutic drug monitor...
    Medical condition: Prophylaxis of rejection in kidney allograft recipients (by immunosuppression)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-004772-21 Sponsor Protocol Number: Dual_Hydrocortisone_gluc_variabilit Start Date*: 2018-02-22
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
    Full Title: Dual-release hydrocortisone compared to immediate-release glucocorticoid replacement therapy in terms of glucose control, insulin sensitivity and glucose variability in patients with adrenal insuff...
    Medical condition: adrenal insufficienty
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10001367 Adrenal insufficiency PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-005216-15 Sponsor Protocol Number: ABO-NB-15 Start Date*: 2016-07-06
    Sponsor Name:ABOCA S.P.A. SOCIETà AGRICOLA
    Full Title: Relief of heartburn and epigastric pain comparing Neobianacid® with omeprazole: a randomized, double blind, double dummy, reference product controlled, parallel group, non-inferiority clinical study
    Medical condition: GERD (Gastroesophageal Reflux Disease) and/or EPS (Epigastric Pain Syndrome)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10015015 Epigastric burning LLT
    20.1 100000004856 10066998 Gastroesophageal burning LLT
    20.1 100000004856 10066990 Gastrooesophageal burning LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004576-34 Sponsor Protocol Number: GECP20/10 Start Date*: 2022-03-21
    Sponsor Name:Fundación GECP
    Full Title: Phase II clinical trial of AMG510 (Sotorasib) in stage III unresectable NSCLC KRAS p.G12C patients and medically ineligible for concurrent chemo-radiotherapy_(MERIT-lung)
    Medical condition: Unresectable stage III (IIIA-N2, IIIB, IIIC) KRAS p.G12C non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029519 Non-small cell lung cancer stage III PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002191-16 Sponsor Protocol Number: ML25153 Start Date*: 2011-07-22
    Sponsor Name:Medizinische Universität Wien, Univ.Klink f. Innere Medizin I
    Full Title: A Phase II pilot study to assess efficacy and safety of capecitabine and irinotecan plus bevacizumab followed by capecitabine and oxaliplatin plus bevacizumab or the reverse sequence in patients wi...
    Medical condition: Histologically or cytologically confirmed carcinoma of the colon and/or rectum with evidence of metastases. Diagnosis of metastatic disease according to RECIST not more than 3 months prior to e...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004864 10010028 Colorectal cancer Duke's D LLT
    18.1 100000004864 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-018316-32 Sponsor Protocol Number: D589GC00002 Start Date*: 2010-11-23
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase 2, randomized, blinded, 5-period cross-over, placebo and activecontrolled, multicenter, dose-finding study of single doses of formoterol 2.25 μg, 4.5 μg, and 9 μg delivered via Symbicort pM...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003553 Asthma LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2016-001158-16 Sponsor Protocol Number: B7541002 Start Date*: 2016-12-05
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 2A, MULTICENTER, SINGLE ARM, OPEN-LABEL, TWO-STAGE, STUDY TO EVALUATE THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF PF-06480605 IN SUBJECTS WITH MODERATE TO SEVERE ULCERATIVE C...
    Medical condition: Ulcerative colitis (UC)
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) PL (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-004286-25 Sponsor Protocol Number: CX-401/FATT2 Start Date*: 2008-12-04
    Sponsor Name:CELLERIX S.A.
    Full Title: Estudio fase III, multicéntrico, simple ciego, randomizado, controlado con placebo, para evaluar la eficacia y seguridad de células madre expandidas derivadas de tejido adiposo autólogo (eASCs) (CX...
    Medical condition: Fístula perianal compleja en pacientes con enfermedad de Crohn. Complex perianal fistula in perianal Crohn´s disease
    Disease: Version SOC Term Classification Code Term Level
    9 10002156 Anal fistula LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) NL (Completed) AT (Prematurely Ended) DE (Prematurely Ended) BE (Completed) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004271-19 Sponsor Protocol Number: RLX.CHF.003 Start Date*: 2008-02-26
    Sponsor Name:Corthera, Inc.
    Full Title: A Phase II/III, Multicenter, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Relaxin in Subjects With Acute Heart Failure.
    Medical condition: Patients hospitalized with Acute Heart Failure (AHF), normal to elevated blood pressure, and mild to moderate renal impairment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) IT (Completed) DE (Completed) FR (Completed) GB (Completed) ES (Completed) NL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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