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Clinical trials for Osteoarthritis, Knee AND Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    228 result(s) found for: Osteoarthritis, Knee AND Pain. Displaying page 8 of 12.
    «« First « Previous 4  5  6  7  8  9  10  11  12  Next»
    EudraCT Number: 2013-001303-36 Sponsor Protocol Number: EMH-PRP-2013 Start Date*: 2013-10-31
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
    Full Title: Intrarticular injections of platelet-rich plasma in pain?s treatment of the Osteoarthritic Knee
    Medical condition: Pain?s treatment of the Osteoarthritic Knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-005020-29 Sponsor Protocol Number: R475-OA-1611 Start Date*: 2018-04-10
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Phase 3 Randomized, Double-blind, Multi-dose, Placebo and Naproxen-Controlled Study to Evaluate the Efficacy and Safety of Fasinumab in Patients with Pain Due to Osteoarthritis of the Knee or Hip
    Medical condition: Pain due to osteoarthritis of the knee or hip
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    21.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed) LT (Completed) GB (GB - no longer in EU/EEA) DK (Completed) PL (Completed) HU (Completed) ES (Ongoing) RO (Completed)
    Trial results: View results
    EudraCT Number: 2013-002549-12 Sponsor Protocol Number: A4091064 Start Date*: 2015-09-08
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 3, MULTICENTER, LONG-TERM OBSERVATIONAL STUDY OF SUBJECTS FROM TANEZUMAB STUDIES WHO UNDERGO A TOTAL KNEE, HIP OR SHOULDER REPLACEMENT
    Medical condition: Osteoarthritis of the hip or knee
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10023476 Knee osteoarthritis LLT
    18.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) AT (Completed) ES (Completed) BG (Completed) DE (Completed) PT (Completed) FI (Completed) GB (Completed) SE (Completed) LT (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2009-010423-58 Sponsor Protocol Number: KF5503/42 Start Date*: 2009-08-28
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chr...
    Medical condition: Pain due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2020-003154-80 Sponsor Protocol Number: 2020CLI Start Date*: 2020-12-08
    Sponsor Name:Mucos Pharma GmbH & Co. KG
    Full Title: A Randomized, Double-blind, Placebo-controlled, Crossover Study to Investigate the Mechanism of Action of an Oral Enzyme Treatment with Bromelain, Trypsin and Rutoside versus Placebo in Subjects wi...
    Medical condition: Subjects suffering from knee Osteoarthitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004993-95 Sponsor Protocol Number: CL-033-III-02 Start Date*: 2005-08-18
    Sponsor Name:IDEA AG
    Full Title: A double blind, placebo-controlled evaluation of dose realted safety and efficacy of epicutaneously applied IDEA-033 for 3 months treatment of osteoarthritis of the knee
    Medical condition: Osteoarthritis of the knee joint
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003885-19 Sponsor Protocol Number: NOT-APPLICABLE-HUFA Start Date*: 2023-03-15
    Sponsor Name:NO-COMERCIAL
    Full Title: ECOGUIDED GENICULAR NERVE BLOCK IN PATIENTS WITH KNEE OSTEOARTHRITIS BY LOCAL ANESTHETIC OR BY COMBINATION OF LOCAL ANESTHETIC AND CORTICOID: PLACEBO-CONTROLLED RANDOMIZED BLIND CLINICAL TRIAL
    Medical condition: KNEE OSTEOARTHRITIS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005956-34 Sponsor Protocol Number: 0822-011 Start Date*: 2007-03-14
    Sponsor Name:Merck Sharp & Dohme Ltd
    Full Title: A Phase IIa Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of MK-0822 in Patients with Osteoarthritis
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-001934-16 Sponsor Protocol Number: AMZ001-006 Start Date*: 2018-10-19
    Sponsor Name:Amzell BV
    Full Title: A placebo-controlled, double-blind, randomized, trial of Diclofenac Gel AMZ001 3.06 % for the treatment of knee osteoarthritis symptoms
    Medical condition: Knee Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2015-005681-37 Sponsor Protocol Number: CL/BIO/15-005 Start Date*: 2016-04-18
    Sponsor Name:BIOIBERICA S.A.
    Full Title: Evaluation of the evolution of imaging markers of cartilage degradation in patients with knee osteoarthritis receiving DROGLICAN®: a Pilot Study
    Medical condition: Knee Osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004076-21 Sponsor Protocol Number: EU001 Start Date*: 2005-10-27
    Sponsor Name:ESTHER URIARTE ITZAZELAIA
    Full Title: A randomized clinical trial to investigate the efficacy and safety of the combination of intra-articular hyaluronan and corticosteroids for osteoarthritis of the knee Ensayo clínico aleatorizado pa...
    Medical condition: OSTEOARTHRITIS OF THE KNEE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015527-82 Sponsor Protocol Number: GRT-CG5503-2009-01-ES Start Date*: 2009-11-20
    Sponsor Name:Grünenthal Pharma S.A.
    Full Title: Estudio abierto de extensión para los pacientes con lumbalgia crónica severa o dolor crónico severo debido a artrosis de rodilla que han completado alguno de los ensayos clínicos previos de fase II...
    Medical condition: Artrosis de rodilla y lumbalgia
    Disease: Version SOC Term Classification Code Term Level
    12.0 10024891 Low back pain LLT
    12.0 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-003437-42 Sponsor Protocol Number: DULKOA2019 Start Date*: 2019-10-31
    Sponsor Name:Lars Arendt-Nielsen
    Full Title: A Mechanism Based Proof of Concept Study of the Effects of Duloxetine in the Treatment of Patients with Osteoarthritic Knee Pain
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-003258-87 Sponsor Protocol Number: DRI6091 Start Date*: 2006-03-09
    Sponsor Name:Sanofi Aventis Deutschland GmbH
    Full Title: Efficacy and safety of intra-articular multiple doses of 500 µg icatibant including 40 mg triamcinolone as calibrator in a randomized, double-blind, parallel-group, placebo-controlled 13-week multi...
    Medical condition: Subjects with painful osteoarthritis in the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) SI (Completed) LT (Completed) CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2017-004049-26 Sponsor Protocol Number: MTX-071-P02 Start Date*: 2017-11-23
    Sponsor Name:Mestex
    Full Title: Lopain (MTX-071 / resiniferatoxin) An open label, single dose phase Ib/IIa study to determine the safety and clinical effects of intra-articular injections of low doses of Lopain (MTX-071) in pa...
    Medical condition: chronic osteoarthritic knee-joint pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004254-26 Sponsor Protocol Number: 2PX-OA-01 Start Date*: 2006-02-16
    Sponsor Name:Santosolve A/S
    Full Title: A double-blind, placebo-controlled, enriched enrolment, randomized-withdrawal study to evaluate the efficacy and safety of 2PX in patients with pain due to osteoarthritis of the knee
    Medical condition: Patients with osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003322-28 Sponsor Protocol Number: BUP4006 Start Date*: 2007-06-21
    Sponsor Name:Norpharma A/S
    Full Title: A randomised, double-blind, multicentre non-inferiority study with active, parallel comparator group, to evaluate the efficacy and safety of Norspan® versus Tramadol in subjects with chronic, mode...
    Medical condition: Chronic, moderate to severe osteoarthritis in hip, knee and/or lumbar spine
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003233-32 Sponsor Protocol Number: BUP4009 Start Date*: 2006-09-12
    Sponsor Name:Mundipharma AB
    Full Title: A randomized, open, controlled parallel group, multi-center study to evaluate the efficacy and safety of Norspan versus Tiparol Retard in subjects with chronic, moderate to severe osteoarthritis pa...
    Medical condition: Pain due to osteoarthritis of the hip and/or knee
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-000623-27 Sponsor Protocol Number: EC_01_2017 Start Date*: 2017-09-11
    Sponsor Name:Fundacion para la investigacion biomedica HUPA
    Full Title: Role of autologous biological therapy in knee osteoarthritis. Intraosseous application of plasma rich in growth factors , improve of functional capacity and pain, compared to intraarticular applic...
    Medical condition: Knee osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003797-51 Sponsor Protocol Number: D5680C00003 Start Date*: 2021-07-20
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomised, Double-blind, Placebo-controlled, Dose-response Study of the Efficacy and Safety of MEDI7352 in Subjects with Painful Osteoarthritis of the Knee
    Medical condition: Painful osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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