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Clinical trials for colon cancer

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    765 result(s) found for: colon cancer. Displaying page 8 of 39.
    EudraCT Number: 2009-009863-75 Sponsor Protocol Number: CEAEP_2009-05-29 Start Date*: 2009-08-26
    Sponsor Name:Karolinska Institutet/ Hospital
    Full Title: El-porCEA: Assessment of safety and immunogenicity of intradermal electroporation of tetwtCEA DNA in patients with colorectal cancer.
    Medical condition: Colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004232-22 Sponsor Protocol Number: SIC Start Date*: 2009-03-24
    Sponsor Name:Odense University Hospital
    Full Title: Phase II study with cetuximab, irinotecan and sunitinib (CIS) for patients with treatment resistant colorectal cancer
    Medical condition: Patients resistant to treatment of colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061451 Colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-002086-29 Sponsor Protocol Number: FFCD1404 Start Date*: 2015-09-04
    Sponsor Name:FEDERATION FRANCOPHONE DE CANCEROLOGIE DIGESTIVE
    Full Title: PHASE II STUDY EVALUATION OF EFFICACITY AND TOLERANCE OF REGORAFENIB FOR 70 YEARS OLD AND MORE PATIENTS WITH A METASTATIC COLORECTAL ADENOCARCIMA
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2006-003349-17 Sponsor Protocol Number: TS-003-DK Start Date*: 2007-08-13
    Sponsor Name:Hvidovre Hospital
    Full Title: Applicability of TachoSil® in sealing rectal anastomoses. A feasibility trial.
    Medical condition: Sealing of rectal anastomoses following surgery for colo-rectal cancer.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061451 Colorectal cancer LLT
    Population Age: Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003939-30 Sponsor Protocol Number: CA209-142 Start Date*: 2014-03-21
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase 2 Clinical Trial of Nivolumab and Nivolumab Plus Ipilimumab in Recurrent and Metastatic Microsatellite High (MSI-H) Colon Cancer
    Medical condition: MSI Positive Colorectal Cancer MSI Negative Colorectal Cancer
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) BE (Trial now transitioned) IE (Completed) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-002364-25 Sponsor Protocol Number: NOR-01/2011(PDR) Start Date*: 2011-10-31
    Sponsor Name:Norgine Limited
    Full Title: A multi-centre, randomised, investigator-blinded study comparing the polyp detection rate of two different types of bowel preparation: a 2-litre solution (MOVIPREP®) versus a hyperosmotic and stimu...
    Medical condition: Patients with clinical symptoms or polyp history scheduled for either a diagnostic/surveillance colonoscopy or for a screening procedure in patients with a personal or familial risk of colon neopla...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022891 - Investigations 10010007 Colonoscopy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017620-11 Sponsor Protocol Number: KINURA-2 Start Date*: 2011-06-14
    Sponsor Name:Scheper Ziekenhuis
    Full Title: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij patiënten met colorectaal carcinoom.
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    12.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004226-82 Sponsor Protocol Number: 10077 Start Date*: 2006-09-07
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: PHARMACODYNAMIC STUDY OF ORAL MIRTOSELECT IN PATIENTS WITH SUSPECTED COLORECTAL DISEASE
    Medical condition: Patients with operable colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10061451 Colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001664-34 Sponsor Protocol Number: 12028-FC-SS Start Date*: 2013-08-30
    Sponsor Name:Belfast HSC Trust [...]
    1. Belfast HSC Trust
    2. Queens University Belfast
    Full Title: Vit-D in CRC - A Randomised Double Blind Placebo-Controlled Clinical Trial Of a Single Oral Cholecalciferol Treatment Against Surrogate End Point Biomarkers (SEBs) In Colon Cancer (CRC) Patients
    Medical condition: Colon cancer
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001054-22 Sponsor Protocol Number: OPMICS-1 Start Date*: 2020-09-21
    Sponsor Name:Claus Anders Bertelsen
    Full Title: Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block in Minimally Invasive Colon Surgery: A Randomized Controlled Multicentre Clinical Trial
    Medical condition: Colon cancer patients undergoing elective minimally invasive colon surgery and receiving a transversus abdominis plane block for postoperative pain management. Ropivacaine is used as the local anal...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-007665-22 Sponsor Protocol Number: 34720696 Start Date*: 2008-12-18
    Sponsor Name:Vejle Sygehus
    Full Title: En fase II undersøgelse af Temsirolimus og Irinotecan til behandlingsresistente patienter med metastaserende colorectal cancer og KRAS mutationer
    Medical condition: Behandlingsresistente patienter med metastaserende colorectal cancer og KRAS mutationer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    9.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-002744-28 Sponsor Protocol Number: IOM-510-2 Start Date*: 2006-09-12
    Sponsor Name:iOMEDICO
    Full Title: Effektivitätsoptimierte und toxizitätsreduzierte Therapie des metastasierten Kolorektalkarzinoms in der First-line Therapie
    Medical condition: metastastic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000401-91 Sponsor Protocol Number: iMAGINE Start Date*: 2020-06-26
    Sponsor Name:Medizinische Universität Wien
    Full Title: iMmunoscore Associated decision GuIdance for adjuvaNt chemotherapy and physical Exercise in stage III colon cancer (iMAGINE): a prospective, randomized, open-label, multicenter, phase III clinical ...
    Medical condition: • Histologically confirmed stage III carcinoma of the colon • Medical need for an standard adjuvant chemotherapy • Suitable to withstand the course of an standard adjuvant chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009955 Colon cancer stage III PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004188-65 Sponsor Protocol Number: KFE-11.17 Start Date*: 2012-03-05
    Sponsor Name:Odense University Hospital
    Full Title: Potentially resectable metastatic colorectal cancer with wild-type KRAS and BRAF: alternating chemotherapy plus cetuximab - A randomised phase II trial - Nordic 7.6
    Medical condition: Metastatic colorectal cancer with wild-type KRAS and BRAF
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-003466-25 Sponsor Protocol Number: 13.024 Start Date*: 2014-12-18
    Sponsor Name:Anders Gadegaard Jensen,Anesthesia and Intensive Care Unit, Odense University Hospital
    Full Title: Randomized, double-blind, prospective, placebo-controlled trial of the effect of intravenous lidocaine infusion for postoperative pain management and bowel function in robot assisted laparoscopic c...
    Medical condition: Postoperative pain after colon rectal cancer surgery are mainly intended to relieve as well resting as activity-induced pain. Secondarily, the choice of pain management should take into considerati...
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004864 10018017 Gastrointestinal tract cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-005999-18 Sponsor Protocol Number: PI20/01514 Start Date*: 2022-06-24
    Sponsor Name:Instituto de Investigación Sanitaria Aragón
    Full Title: Effect of obesity on COX1 and 2 acetylation by aspirin as a biomarker of its efficacy in colon cancer chemoprevention and therapy.
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003275-30 Sponsor Protocol Number: 011-IRCC-10IIS-15 Start Date*: Information not available in EudraCT
    Sponsor Name:FONDAZIONE DEL PIEMONTE PER L'ONCOLOGIA IRCCS
    Full Title: Open-label, phase ii study of trastuzumab emtansine in patients with HER2-positive metastatic colorectal cancer progressing after trastuzumab and lapatinib: (HER2 Amplification for Colo-rectaL canc...
    Medical condition: metatastatic colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10001172 Adenocarcinoma of colon stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000159-15 Sponsor Protocol Number: PRTK15-TL/SONCHIMIO Start Date*: 2018-01-12
    Sponsor Name:CHRU TOURS
    Full Title: Targeted delivery of chemotherapy with ultrasound and microbubbles
    Medical condition: Colo-Rectal Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052362 Metastatic colorectal cancer LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-003179-20 Sponsor Protocol Number: 71065 Start Date*: 2020-03-23
    Sponsor Name:Meander Medical Centre
    Full Title: ‘A pilot study to assess the safety and feasibility of fluorescent sentinel lymph node identification in colon carcinoma using Indocyanine green’
    Medical condition: Colon carcinoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002325-18 Sponsor Protocol Number: CATARTIC Start Date*: 2021-09-28
    Sponsor Name:FONDAZIONE IRCCS "ISTITUTO NAZIONALE DEI TUMORI"
    Full Title: Multicenter phase II study of preoperative chemoradiotherapy with CApecitabine plus Temozolomide in patients with MGMT silenced and microsatellite stable locally Advanced RecTal Cancer: the CATARTI...
    Medical condition: Localy advanced low-risk rectal cancer, placed at less then 15 cm form the anal verge and staged as cT = 2 and cN0 or cT1-3 cN1 (TNM classification 8th edition), without evidence of distant metasta...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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