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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 873 of 2,219.
    EudraCT Number: 2009-011497-15 Sponsor Protocol Number: CERA Start Date*: 2009-05-07
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: PILOT CLINICAL TRIAL WITH MIRCERA (methoxy polyethylene glycol-epoetin beta) IN DIALYSIS UNIT OF A.O. SAN GIOVANNI BATTISTA DI TORINO
    Medical condition: End stage renal patients in hemodialysis or peritoneal dialysis treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001468-34 Sponsor Protocol Number: HLS01/2008 Start Date*: 2008-11-20
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Phase III clinical trial multicenter randomized for the evaluation of the safety and efficacy of the combined treatment of intravitreal triamcinolone and photodynamic therapy versus intravitreal Be...
    Medical condition: Choroideal neo-vascularization type RAP.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015919 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007455-26 Sponsor Protocol Number: GS-US-235-0101 Start Date*: 2010-01-21
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: A Phase 2, Randomized, Double-blind, Placebo-controlled, Multicenter, Dose-ranging Study of Cicletanine in Subjects with Pulmonary Arterial Hypertension
    Medical condition: Pulmonary hypertension (PH) is a serious and life-threatening disease of the pulmonary vasculature, characterized by profound vasoconstriction and an abnormal proliferation of smooth muscle cells i...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) DE (Prematurely Ended) BE (Prematurely Ended) GB (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-005175-10 Sponsor Protocol Number: ABD03 Start Date*: 2009-04-08
    Sponsor Name:Guys and St Thomas' NHS Foudation Trust
    Full Title: Volume Expansion using a balanced gelatin solution in patients undergoing major abdominal surgery.
    Medical condition: Intravascular volume deficits in major abdominal surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021137 Hypovolaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008723-15 Sponsor Protocol Number: 2009-01 Start Date*: 2009-04-22
    Sponsor Name:Örebro University Hospital
    Full Title: Postoperative Pain Relief following Total Hip Arthroplasty. A comparison between Intrathecal morphine (IM) and Local Infiltration Analgesia (LIA).
    Medical condition: Postoperative pain following total hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011742-26 Sponsor Protocol Number: TetDip-2009 Start Date*: 2009-04-14
    Sponsor Name:Institute for Biomedical Aging Research
    Full Title: Humoral and cellular immune response against tetanus and diphtheria following booster vaccination
    Medical condition: This study will analyze cellular and humoral immune responses after booster vaccination. Healthy adults are vaccinated against tetanus, diphtheria, pertussis and polio on a regular basis. This stud...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039244 Routine vaccination LLT
    9.1 10054183 Tetanus immunization LLT
    9.1 10054180 Diphtheria immunization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006328-75 Sponsor Protocol Number: P071212 Start Date*: 2009-05-11
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: NOCETER essai multicentrique randomisé en double aveugle contre placebo. Réduction du taux de CEsariennes chez les patientes dépassant le TERme: Impact d'une maturation cervicale ambulatoire par do...
    Medical condition: Chez les femmes qui ont dépasser le terme d'accouchement (41 SA+0)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10036656 Dépassement du terme d'accouchement (41SA+0) PT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006430-10 Sponsor Protocol Number: CTKI258A2202 Start Date*: 2009-06-22
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-center, open label Phase II trial of TKI258 in FGFR1 amplified and non-amplified metastatic HER2 negative breast cancer.
    Medical condition: In female patients with FGFR1 amplified and non-amplified metastatic HER2 negative breast cancer.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006187 Breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FI (Prematurely Ended) ES (Prematurely Ended) FR (Completed) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012019-17 Sponsor Protocol Number: BO22280 Start Date*: 2009-09-02
    Sponsor Name:F. Hoffmann - La Roche Ltd
    Full Title: A randomised, multicentre, multinational Phase II study to evaluate pertuzumab in combination with trastuzumab given either concomitantly or sequentially with standard anthracycline based chemother...
    Medical condition: Locally advanced, inflammatory or early stage HER2-positive breast cancer.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10065430 HER-2 positive breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed) DE (Completed) GB (Completed) PT (Completed) GR (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005276-27 Sponsor Protocol Number: FE 200486 CS35 Start Date*: 2009-07-17
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: An Open-Label, Multi-Centre, Randomised, Parallel-Arm One-Year Trial, Comparing the Efficacy and Safety of Degarelix Three-Month Dosing Regimen with Goserelin Acetate in Patients with Prostate Canc...
    Medical condition: prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: HU (Completed) NL (Completed) DE (Completed) FI (Completed) CZ (Completed) GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012000-10 Sponsor Protocol Number: MK-7009, 019 Start Date*: 2009-07-13
    Sponsor Name:Merck Sharp & Dohme (Europe) Inc.
    Full Title: A Phase II Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of Different Regimens of MK-7009 When Administered Concomitantly with Pegylated Interferon and Rib...
    Medical condition: Chronic hepatitis C infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019751 Hepatitis C virus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) DE (Prematurely Ended) GB (Prematurely Ended) AT (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015890-11 Sponsor Protocol Number: AGO/2009/007 Start Date*: 2009-11-03
    Sponsor Name:University Hospital Ghent
    Full Title: Conditioning with volatile anesthetics in liver transplantation
    Medical condition: Liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    12.0 10024716 Liver transplantation LLT
    Population Age: Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012088-32 Sponsor Protocol Number: KKSH-066 Start Date*: 2010-01-07
    Sponsor Name:Martin-Luther-Universität Halle-Wittenberg
    Full Title: Prospektive und randomisierte Multicenter-Studie (Phase III-Studie) zur Verbesserung der Funktion des Nervus facialis und des Nervus vestibulocochlearis nach der Resektion von Akustikusneurinomen d...
    Medical condition: Akustikusneurinom mit Indikation zur operativen Therapie
    Disease: Version SOC Term Classification Code Term Level
    12.0 10000522 Acoustic neurinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015795-10 Sponsor Protocol Number: SMA-09-19-SVN Start Date*: 2009-11-12
    Sponsor Name:Alcon d.o.o.
    Full Title: Assessing the safety and efficacy of switching to Azarga (Brinzolamide/Timolol Fixed Combination), as replacement therapy in patients with uncontrolled intraocular pressure
    Medical condition: uncontrolled intraocular pressure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2009-011758-16 Sponsor Protocol Number: 1.1 Start Date*: 2009-12-16
    Sponsor Name:Karolinska University Hospital Huddinge
    Full Title: A randomized placebo controlled trial of vitamin D3 supplementation to a vulnerable patientsgroup susceptible to uppertract respiratory infections.
    Medical condition: Patients with primary or secondary immunodeficiencies and/or patients who have an increased incidence of airborn infections more than 42 infectionsday /year.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013174-41 Sponsor Protocol Number: CRPC2 Start Date*: 2009-10-14
    Sponsor Name:Medivation, Inc.
    Full Title: AFFIRM: A Multinational Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Oral MDV3100 in Patients with Progressive Castration-Resistant Prostate Cancer Previously ...
    Medical condition: Patients with progressive castration-resistant prostate cancer previously treated with docetaxel-based chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: BE (Completed) GB (Completed) FR (Completed) ES (Completed) DE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008177-57 Sponsor Protocol Number: AN08/8748 Start Date*: 2009-06-05
    Sponsor Name:University of Leeds
    Full Title: “What is the ED95 dose of Prilocaine for femoral nerve block using ultrasound?”
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012418-38 Sponsor Protocol Number: CICL670A2302 Start Date*: 2009-12-18
    Sponsor Name:NOVARTIS FARMA
    Full Title: A multi-center, randomized, double-blind, placebocontrolled clinical trial of deferasirox in patients with myelodysplastic syndromes (low/int-1 risk) and transfusional iron overload
    Medical condition: myelodysplastic syndromes(low/int-1 risk)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019613 Hemosiderosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) FI (Prematurely Ended) DK (Completed) GB (Completed) BE (Completed) GR (Completed) NL (Prematurely Ended) BG (Completed)
    Trial results: View results
    EudraCT Number: 2009-014272-21 Sponsor Protocol Number: IC2009exe001 Start Date*: 2009-11-03
    Sponsor Name:VU University Medical Center
    Full Title: Effect of additional treatment with exenatide in patients with an acute myocardial infarction: the EXAMI trial)
    Medical condition: Acute Myocardial Infartion to be treated with primary PCI
    Disease: Version SOC Term Classification Code Term Level
    12.0 10000891 Acute myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015773-12 Sponsor Protocol Number: 6096-011 Start Date*: 2010-01-08
    Sponsor Name:Merck & Co. Inc.
    Full Title: A Phase IIb, Multicenter, Randomized, Double-Blind, Placebo-Controlled, 2-Period Adaptive Crossover Polysomnography Study to Evaluate the Safety and Efficacy of MK 6096 in Patients with Primary Ins...
    Medical condition: Primary insomnia
    Disease: Version SOC Term Classification Code Term Level
    12.0 10036701 Primary insomnia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) FI (Completed) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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