Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Acute heart failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    511 result(s) found for: Acute heart failure. Displaying page 9 of 26.
    EudraCT Number: 2008-005140-16 Sponsor Protocol Number: KAI-9803-004 Start Date*: 2009-06-02
    Sponsor Name:KAI Pharmaceuticals, Inc
    Full Title: Inhibition of δ-PROTEin kinase C for the reducTION of infarct size in Acute Myocardial Infarction (PROTECTION AMI)
    Medical condition: Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000891 Acute myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) ES (Completed) HU (Completed) CZ (Completed) PT (Completed) BE (Completed) SE (Completed) FI (Completed) IT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-000255-13 Sponsor Protocol Number: 11-019 Start Date*: 2012-06-20
    Sponsor Name:Portola Pharmaceuticals, Inc.
    Full Title: Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Me...
    Medical condition: Prophylaxis of venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) LV (Completed) DE (Completed) ES (Completed) GB (Completed) PL (Completed) LT (Completed) AT (Completed) DK (Completed) CZ (Completed) BG (Completed) IT (Completed) FI (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2010-018436-41 Sponsor Protocol Number: Bay 63-2521/14554 Start Date*: 2010-05-11
    Sponsor Name:Bayer HealthCare AG
    Full Title: Acute hemoDynamic effects of RIociguat (BAY 63-2521) in patients with puLmonary hypertension Associated with diasTolic heart failurE (DILATE 1): A randomized, double-blind, placebo-controlled, sin...
    Medical condition: Pulmonary hypertension associated with diastolic heart failure
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037405 Pulmonary hypertension primary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) CZ (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000983-41 Sponsor Protocol Number: ID-076A301 Start Date*: 2021-11-03
    Sponsor Name:Idorsia Pharmaceuticals Ltd
    Full Title: Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death a...
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned) SK (Trial now transitioned) DK (Trial now transitioned) EE (Trial now transitioned) LT (Trial now transitioned) ES (Ongoing) AT (Trial now transitioned) BG (Trial now transitioned) FR (Trial now transitioned) NO (Trial now transitioned) HU (Trial now transitioned) PL (Trial now transitioned) CZ (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned) NL (Trial now transitioned) IE (Prematurely Ended) GR (Trial now transitioned) PT (Trial now transitioned) RO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-007864-63 Sponsor Protocol Number: Abciximab-STEMI Start Date*: 2008-06-18
    Sponsor Name:University of Leipzig
    Full Title: Prospective, randomized and controlled clinical trial comparing i.v. bolus application of Abciximab to i.c.application of Abciximab during primary PCU in patients with acute ST-elevation myocardial...
    Medical condition: ST-elevation myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000891 Acute myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001437-27 Sponsor Protocol Number: P150801 Start Date*: 2016-12-30
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Efficacy of furosemide versus vascular filling in Patients with Acute Myocardial Infarction with Right Ventricular Extension: a multicentric randomized controlled trial.
    Medical condition: Myocardial infarction with right ventricular extension.
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004625-42 Sponsor Protocol Number: KardioPII Start Date*: 2009-01-09
    Sponsor Name:Asklepios Kliniken Hamburg GmbH
    Full Title: Percutaneous Intramyocardial Cell Therapy After Acute Myocardial Infarction using Bone Marrow Mononuclear Cells
    Medical condition: Acute myocardial infarction (LVEF<45%) ICD10: I21.9
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017589-22 Sponsor Protocol Number: AGO/2009/013 Start Date*: 2010-01-14
    Sponsor Name:University Hospital Ghent
    Full Title: Interacties tussen hart en nieren tijdens de behandeling van gedecompenseerd hartfalen: diuretica versus ultrafiltratie (CRUF Trial)
    Medical condition: Patiënten met ernstig gedecompenseerd hartfalen
    Disease: Version SOC Term Classification Code Term Level
    12.1 10066159 Decompensated heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-002813-33 Sponsor Protocol Number: ARMYDA-9DAPAtrial Start Date*: 2023-02-21
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA MAGGIORE DELLA CARITà DI NOVARA
    Full Title: Early use of dapaglifozin in diabetic patients with acute myocardial infarction and reduced ejection fraction: the randomized ARMYDA-9 DAPA trial
    Medical condition: Patients with type 2 diabetes and ST-elevation myocardial infarction treated with primary primary percutaneous coronary intervention and reduced left ventricle ejection fraction.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064346 STEMI LLT
    20.0 100000004849 10011949 Decompensation cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002161-19 Sponsor Protocol Number: 13062017-23-1 Start Date*: 2018-06-25
    Sponsor Name:Fakultní nemocnice Královské Vinohrady
    Full Title: Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction
    Medical condition: Cardiogenic shock in acute myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed) FR (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001452-11 Sponsor Protocol Number: 201103 Start Date*: 2011-06-07
    Sponsor Name:Skånes Universitetssjukhus Lund
    Full Title: Supplemental Oxygen in Catherized Coronary Emergency Reperfusion
    Medical condition: Acute ST elevation myocardial infaction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005383-22 Sponsor Protocol Number: Kognition Start Date*: 2022-07-27
    Sponsor Name:Universitätsmedizin Göttingen
    Full Title: Cognitive Function, Depression, Anxiety, and Quality of Life in Chronic Heart Failure Patients with Iron Deficiency with and without Anaemia: Effects of Intravenous Iron (Ferric Derisomaltose)
    Medical condition: Iron deficiency in patients with chronic heart failure and mild cognitive impairment
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-004319-29 Sponsor Protocol Number: P170914J Start Date*: 2021-10-04
    Sponsor Name:ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (AP-HP)
    Full Title: " LEVOSIMENDAN to facilitate weaning from ECMO in severe cardiogenic shock patients
    Medical condition: Adult patients with acute cardiogenic shock refractory to conventional therapy placed on VA-ECMO support and for whom withdrawal from ECMO is possible.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007625 Cardiogenic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006637-19 Sponsor Protocol Number: CARDIOL100-002 Start Date*: 2022-12-01
    Sponsor Name:Cardiol Therapeutics Inc.
    Full Title: Impact of CardiolRxTM on Myocardial Recovery in Patients with Acute Myocarditis A double-blind, placebo-controlled trial (ARCHER)
    Medical condition: Acute Myocarditis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000932 Acute myocarditis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-003652-20 Sponsor Protocol Number: Ptcl-01501 Start Date*: 2013-12-04
    Sponsor Name:D-Pharm Ltd.
    Full Title: Pilot trial of intravenous DP-b99 in the treatment of first-ever episode of non-obstructive acute high-risk pancreatitis
    Medical condition: Acute pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004856 10000971 Acute pancreatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002485-40 Sponsor Protocol Number: REBOOT-CNIC Start Date*: 2018-03-22
    Sponsor Name:CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (CNIC)
    Full Title: treatment with beta-blockers after myocardial infarction without reduced ejection fraction
    Medical condition: STEMI or NSTEMI patients being discharged from the index hospitalization with a LVEF>40% without previous heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004293-15 Sponsor Protocol Number: UCART19_02(CL1-68587-001) Start Date*: 2016-05-24
    Sponsor Name:Institut de Recherches Internationales Servier (I.R.I.S)
    Full Title: A phase 1, open label, non-comparative, study to evaluate the safety and the ability of UCART19 to induce molecular remission in paediatric patients with relapsed /refractory B-cell acute lymphobla...
    Medical condition: Paediatric relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10060390 Leukaemia lymphoblastic acute LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) FR (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-003797-23 Sponsor Protocol Number: KKS-305 Start Date*: 2023-05-16
    Sponsor Name:Philipps University Marburg
    Full Title: Myeloperoxidase inhibition in patients with ischemic or non-ischemic cardiomyopathy and heart failure with reduced ejection fraction
    Medical condition: Ischemic or non-ischemic cardiomyopathy and heart failure with reduced ejection fraction. Danke
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    27.0 10007541 - Cardiac disorders 10078289 Heart failure with reduced ejection fraction PT
    20.0 10007541 - Cardiac disorders 10055222 Non-ischemic cardiomyopathy LLT
    20.0 10007541 - Cardiac disorders 10055217 Ischemic cardiomyopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000602-18 Sponsor Protocol Number: BMT-CTN#1301 Start Date*: 2016-09-26
    Sponsor Name:National Heart, Lung, and Blood Institute (NHLBI)
    Full Title: A Randomized, Multi-Center, Phase III Trial of Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus Host-Disease
    Medical condition: Acute Leukemia in morphologic complete remission Myelodisplasia with less than 5% blasts in the marrow and no circulating blasts
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004864 10024330 Leukemia acute LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002429-39 Sponsor Protocol Number: Leodor2017 Start Date*: 2017-10-27
    Sponsor Name:Medical University Innsbruck
    Full Title: REPETITIVE LEVOSIMENDAN INFUSIONS FOR PATIENTS WITH ADVANCED CHRONIC HEART FAILURE
    Medical condition: Advanced chronic heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed) HU (Completed) SI (Completed) FI (Completed) DK (Prematurely Ended) IT (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Wed Jun 18 10:00:35 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA