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Clinical trials for Heart surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    628 result(s) found for: Heart surgery. Displaying page 9 of 32.
    «« First « Previous 5  6  7  8  9  10  11  12  13  Next» Last»»
    EudraCT Number: 2010-022027-30 Sponsor Protocol Number: VIT001 Start Date*: 2010-09-23
    Sponsor Name:UZ Gasthuisberg
    Full Title: A randomized placebo-controlled double blind study to prevent BOS
    Medical condition: A study to prevent the occurence of chronic rejection after lung transplantation. Other points of investigation include lung function evolution, rate of survival, BAL cellularity, infection rate, r...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10029888 Obliterative bronchiolitis LLT
    12.1 10049202 Bronchiolitis obliterans LLT
    12.1 10068805 Follicular bronchiolitis LLT
    12.1 10019319 Heart-lung transplant rejection LLT
    12.1 10025127 Lung transplant LLT
    12.1 10050433 Prophylaxis against lung transplant rejection LLT
    12.1 10050437 Prophylaxis against heart and lung transplant rejection LLT
    12.1 10051604 Lung transplant rejection LLT
    12.1 10056409 Heart and lung transplant LLT
    12.1 10016547 FEV LLT
    12.1 10016549 FEV 1 abnormal LLT
    12.1 10016550 FEV 1 decreased LLT
    12.1 10016553 FEV 1 low LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001357-26 Sponsor Protocol Number: 13-036 Start Date*: 2014-08-04
    Sponsor Name:Clinical Trial Center Aachen
    Full Title: HIGH DOSE SUPPLEMENTATION OF SELENIUM IN LEFT VENTRICULAR ASSIST DEVICE (LVAD) IMPLANT SURGERY – A DOUBLE BLIND RANDOMISED CONTROLLED TRIAL
    Medical condition: Selenium is a key component of a number of selenoproteins which protect against oxidative stress and is well recognised for its prominent role in immune defence. Selenoproteins have the potential t...
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004848 10040397 Serum selenium decreased LLT
    17.0 100000004848 10039918 Selenium LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-000757-49 Sponsor Protocol Number: QRK309 Start Date*: 2018-12-05
    Sponsor Name:Quark Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of QPI-1002 for the Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for A...
    Medical condition: QPI-1002 is being developed for prevention of acute kidney injury (AKI) in patients at risk for AKI following cardiac surgery and for reduction in the incidence and severity of delayed graft functi...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) GB (GB - no longer in EU/EEA) BE (Completed) CZ (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003648-31 Sponsor Protocol Number: PKPDHM-001 Start Date*: 2011-11-17
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Pharmacokinetic-pharmacodynamic modeling of the postoperative pain sensation during patient-controlled analgesia with target-controlled infusion of Hydromorphone, taking into account the interactio...
    Medical condition: Pain therapy after elective cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000962-23 Sponsor Protocol Number: REDEX Start Date*: 2014-07-10
    Sponsor Name:Consorci Parc de Salut Mar
    Full Title: Effect of dexmedetomidine on monitoring of motor evoked potentials in patients undergoing supratentorial craniotomy or brainstem surgery
    Medical condition: Patients scheduled for supratentorial craniotomy or brainstem surgery with intraoperative monitoring of motor evoked potentials (MEP).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000134-22 Sponsor Protocol Number: MDCO-CAN-15-01 Start Date*: 2021-01-14
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A Prospective, Open-Label, Single-Arm, Multi-Center Study to Assess The Pharmacokinetics/Pharmacodynamics (PK/PD) AND Safety Of Different Cangrelor Doses In Neonatal Subjects At Risk Of Thrombosis.
    Medical condition: Postoperative neonatal cardiac subjects who are undergoing surgery for placement of systemic-to pulmonary artery palliative shunts (e.g., Blalock-Taussig or central shunt), right ventricle to pulmo...
    Disease:
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-000539-29 Sponsor Protocol Number: 2018.02.08 Start Date*: 2018-12-11
    Sponsor Name:Hamilton Health Sciences Corporation
    Full Title: PeriOperative ISchemic Evaluation-3 (POISE-3) Trial
    Medical condition: The occurrence of life-threatening, major, and critical organ bleeding, and, major arterial and venous thrombosis in patients undergoing noncardiac surgery. And for patients in the blood pressure m...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10043611 Thrombosis arterial LLT
    21.0 100000004866 10043640 Thrombosis venous LLT
    23.1 100000004863 10051014 Post procedural bleeding LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DK (Completed) AT (Completed) NL (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000192-14 Sponsor Protocol Number: TMC-CAN-05-02 Start Date*: 2006-12-21
    Sponsor Name:The Medicines Company
    Full Title: A Clinical Trial Comparing Cangrelor To Clopidogrel In Subjects Who Require Percutaneous Coronary Intervention
    Medical condition: Subjects with coronary atherosclerosis who require PCI (with or without stent).
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011093 Coronary atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) ES (Completed) DE (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-003359-12 Sponsor Protocol Number: CCH2012-02 Start Date*: 2015-02-18
    Sponsor Name:VU University Medical Center
    Full Title: The effect of a high and low protamine-to-heparin dosing on perioperative hemostasis: a randomized clinical trial.
    Medical condition: Patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10006894 CABG LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004744-38 Sponsor Protocol Number: HCA-2017-1 Start Date*: 2018-09-11
    Sponsor Name:Tays Sydänkeskus Oy
    Full Title: New truncal nerve blocks for upper torso. Part 1. Serratus anterior plane block (SAPB): Effect on pain and recovery after thoracoskopic lung surgery. Part 2. Subpectoral interfacial plane block (S...
    Medical condition: Osa 1 (SAPB): Suurin osa keuhkoleikkauksista tehdään keuhkon, keuhkopussin tai välikarsinan muutosten takia. Osa 2 (SIP): Avosydänkirurgiset läppäleikkaukset tehdään sydänläppien vuotojen, ahtaumi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021983-14 Sponsor Protocol Number: MLK002 Start Date*: 2010-09-23
    Sponsor Name:UZ Gasthuisberg
    Full Title: A randomized placebo-controlled double blind study to treat BOS.
    Medical condition: -Mortality at 1 and 2 year post diagnosis of BOS -Infection rate during BOS -Evolution of pulmonary function after diagnosis of BOS
    Disease: Version SOC Term Classification Code Term Level
    12.1 10029888 Obliterative bronchiolitis LLT
    12.1 10049202 Bronchiolitis obliterans LLT
    12.1 10068805 Follicular bronchiolitis LLT
    12.1 10019319 Heart-lung transplant rejection LLT
    12.1 10025127 Lung transplant LLT
    12.1 10051604 Lung transplant rejection LLT
    12.1 10056409 Heart and lung transplant LLT
    12.1 10016547 FEV LLT
    12.1 10016549 FEV 1 abnormal LLT
    12.1 10016550 FEV 1 decreased LLT
    12.1 10016553 FEV 1 low LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-006968-11 Sponsor Protocol Number: AP214-CS005 Start Date*: 2009-04-21
    Sponsor Name:Action Pharma A/S
    Full Title: Pharmacokinectics of AP214 Acetate in patients undergoing cardiac surgery. A randomized, double-blind, placebo-controlled sequential ascending dose trial investigating pharmacokinetics, as well as...
    Medical condition: Action Pharma A/S is developing AP214 Acetate for the prevention of postsurgical kidney injury after thoracic aortic aneurysm repair surgery. In phase 2: Patients undergoing cardiac surgery, defin...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056675 Postoperative renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002217-36 Sponsor Protocol Number: 20130021 Start Date*: 2013-07-04
    Sponsor Name:Dept. of Anaesthesiology, Odense University Hospital
    Full Title: Crystalloid versus colloid for goal directed haemodynamic optimisation in major abdominal cancer surgery.
    Medical condition: Patients undergoing surgery for pancreatic, gastric or esophageal cancer.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10068093 Gastrointestinal surgery PT
    20.0 10042613 - Surgical and medical procedures 10011508 Crystalloid colloid fluid replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-004171-37 Sponsor Protocol Number: CH/2005/1944 Start Date*: 2006-08-02
    Sponsor Name:United Bristol Healthcare Trust
    Full Title: Oxidative Stress in children undergoing cardiopulmonary bypass: A trial of Sildenafil therapy
    Medical condition: Congenital Heart Disease
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008009-23 Sponsor Protocol Number: CALMA Start Date*: 2009-03-23
    Sponsor Name:Servicio de Anestesia-Reanimación
    Full Title: Estudio aleatorizado, doble ciego y controlado sobre la eficacia de la albúmina y manitol en el cebado del sistema de circulación extracorpórea en cirugía cardiaca para reducir el sangrado postoper...
    Medical condition: Cardiac surgery with cardiopulmonary bypass. Postoperative bleeding and requirements of blood products
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066123 Cardiopulmonary bypass LLT
    9.1 10036277 Postoperative bleeding LLT
    9.1 10005765 Blood product transfusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003638-10 Sponsor Protocol Number: 2016_37 Start Date*: Information not available in EudraCT
    Sponsor Name:CHRU LILLE
    Full Title: INTRANASAL CLONIDINE PREDICTION IN PEDIATRIC SURGERY: RANDOMIZED STUDY AGAINST PLACEBO
    Medical condition: intra-nasal premedication instead of oral, intravenous or no premedication.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002354-72 Sponsor Protocol Number: 1.0 Start Date*: 2013-09-05
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: A QUALITATIVE ANALYSIS OF SEDATION IN INFANTS WITH CAUDAL BLOCKADE
    Medical condition: 34 patients aged between 0 and 3 months parted into 2 groups have to undergo caudal block. Group 1 receive a block with 1ml/kg Naropin 3.75% Group 2 receive a block with 1ml/kg Naropin 3.75% and...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-005097-19 Sponsor Protocol Number: EVOLVD Start Date*: 2019-01-23
    Sponsor Name:Oslo University Hospital
    Full Title: Cholesterol lowering with EVOLocumab to prevent cardiac allograft Vasculopathy in De-novo heart transplant recipients
    Medical condition: Cardiac allograft vasculopathy in de-novo heart transplant recipients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed) DK (Completed) FI (Completed) SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003884-37 Sponsor Protocol Number: RONIN-CCV Start Date*: 2023-05-26
    Sponsor Name:Fernando Suarez Sipmann
    Full Title: Role of inhaled nitric oxide on right ventricular function and pulmonary vascular mechanics following cardiac surgery
    Medical condition: Patients in the immediate cardiac surgery post-operative period
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004214-16 Sponsor Protocol Number: FS014 Start Date*: 2005-01-19
    Sponsor Name:Committee of Management, Common Services Agency T/A Scottish National Blood Transfusion Service
    Full Title: A randomised control clinical study to determine whether SNBTS Fibrin Sealant promotes wound healing in patients undergoing cardiac surgery.
    Medical condition: In patients undergoing cardiac surgery the saphenous leg vein is used to replace veins used in coronary artery bypass grafts (CABG) surgery.
    Disease: Version SOC Term Classification Code Term Level
    7.1 10006894 LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
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