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Clinical trials for Osteoarthritis, Knee AND Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    228 result(s) found for: Osteoarthritis, Knee AND Pain. Displaying page 9 of 12.
    «« First « Previous 4  5  6  7  8  9  10  11  12  Next»
    EudraCT Number: 2011-002768-25 Sponsor Protocol Number: 191622-102 Start Date*: 2011-11-10
    Sponsor Name:Allergan Limited
    Full Title: A Single Center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study of the Efficacy and Safety of BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex as Treatment for Osteoa...
    Medical condition: Treatment of Osteoarthritis Knee Pain
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-001669-16 Sponsor Protocol Number: 80-83600-98-3143 Start Date*: 2015-12-21
    Sponsor Name:Erasmus MC
    Full Title: Duloxetine for chronic osteoarthritis pain; an important alternative?
    Medical condition: osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-000204-11 Sponsor Protocol Number: NN9536-4578 Start Date*: 2021-01-11
    Sponsor Name:Novo Nordisk A/S
    Full Title: Effect of subcutaneous semaglutide 2.4 mg once-weekly compared to placebo in subjects with obesity and knee osteoarthritis
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DK (Completed) SE (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2004-001713-34 Sponsor Protocol Number: A3471119 Start Date*: 2005-01-11
    Sponsor Name:Pfizer Limited
    Full Title: RANDOMIZED, DOUBLE-BLIND, MULTICENTER STUDY OF THE EFFICACY, TOLERABILITY AND SAFETY OF VALDECOXIB (BEXTRA®)10 MG OD VS. DICLOFENAC SODIUM 50 MG TDS FOR 6 WEEKS IN SUBJECTS WITH OSTEOARTHRITIS OF T...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    10031161
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006298-26 Sponsor Protocol Number: CL-033-III-03 Start Date*: 2008-04-22
    Sponsor Name:IDEA AG
    Full Title: Multicenter, randomized, double-blind, placebo- and active-controlled study of safety and efficacy of two dosages of epicutaneously applied Diractin® (ketoprofen in Transfersome® gel) for the treat...
    Medical condition: Treatment of osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001754-92 Sponsor Protocol Number: AAE581C2201 Start Date*: 2005-02-14
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A phase II, 12-month, double-blind, placebo-controlled, dose-finding, multicenter study to evaluate the safety, tolerability, and disease modifying efficacy of daily oral AAE581 (10, 25 and 50 mg t...
    Medical condition: Osteoarthritis (OA) is a disease with a complex pathophysiology leading to the degeneration of articular cartilage and bone. It is characterized by pain, biochemical and enzymatic changes, cartilag...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002634-20 Sponsor Protocol Number: NBF_HK_01_2018 Start Date*: 2018-10-23
    Sponsor Name:Anaesthesia Department, Hvidovre Hospital, Capital Region of Denmark
    Full Title: Highdose steroid for total knee arthroplasty - A randomized doubleblindet controlled trial.
    Medical condition: Perioperative management of total knee-arthroplasty because of knee-osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-010425-39 Sponsor Protocol Number: KF5503/43 Start Date*: 2009-09-23
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with severe chronic pain due...
    Medical condition: Pain due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-004999-35 Sponsor Protocol Number: BKOS-04 Start Date*: 2014-04-08
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED, FOUR PARALLEL ARM, DOSE-FINDING STUDY TO EVALUATE THE EFFICACY, SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF SINGLE INTRA-ARTICULAR INJECTIONS OF FA...
    Medical condition: Symptomatic osteoarthritis (OA) of the knee.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2020-002206-10 Sponsor Protocol Number: APHP190891 Start Date*: 2020-07-07
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: A prospective study of the safety and efficacy of the use of a Lipiodol Emulsion for the embolization of inflammatory hypervascularizations observed in patients with articular or abarticular pain i...
    Medical condition: Adult patients with articular or abarticular intractable pain in the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020748-37 Sponsor Protocol Number: BUP4504 Start Date*: 2010-12-01
    Sponsor Name:Mundipharma AB
    Full Title: An open label, multi-centre, prospective age-group-controlled study to evaluate efficacy and safety of buprenorphine transdermal patches in subjects with chronic, moderate to severe osteoarthritis ...
    Medical condition: Osteoarthritis pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005946-35 Sponsor Protocol Number: EFC10096 Start Date*: 2007-05-17
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: Efficacy and safety of 3 intra-articular injections of 500 µg icatibant in a randomized, double-blind, parallel-group, placebo-controlled 13-week multi-centre study in patients with symptomatic kne...
    Medical condition: patients with painful OA in the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2007-004973-25 Sponsor Protocol Number: PIAS005/06 Start Date*: 2008-05-28
    Sponsor Name:Laboratoire Expanscience
    Full Title: Prospective multicentric open clinical study comparing the efficacy and safety of piascledine 300 plus standard treatment versus standard treatment only in patients with osteoarthritis of the knee
    Medical condition: Osteoarthritis of the knee
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-001008-13 Sponsor Protocol Number: 497 Start Date*: 2013-09-18
    Sponsor Name:Sint Maartenskliniek
    Full Title: Fast-track rehabilitation protocol for Total Knee Arthroplasty: A Randomized Controlled Trial comparing Local Infiltration Analgesia with Femoral Nerve Block
    Medical condition: patients requiring total knee arthroplasty for non-inflammatory osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-004052-30 Sponsor Protocol Number: CLNA043X2202 Start Date*: 2017-04-28
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, patient and investigator blinded, Proof of Concept study investigating the safety, tolerability and preliminary efficacy of multiple intra-articular LNA043 injecti...
    Medical condition: Acute cartilage injuries
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) CZ (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-004730-15 Sponsor Protocol Number: R5069-OA-1849 Start Date*: 2019-08-08
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Multi-Dose, Placebo-Controlled Study to Evaluate the Efficacy and Safety of REGN5069 in Patients with Pain due to Osteoarthritis of the Knee
    Medical condition: Pain due to osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004270-25 Sponsor Protocol Number: A3191173 Start Date*: 2005-12-09
    Sponsor Name:Pfizer Ltd
    Full Title: Double-blind, parallel-group, randomized, study of the efficacy and safety of continuous use of celecoxib vs the “usual use” of celecoxib in the treatment of subjects with chronicosteoarthritis of ...
    Medical condition: Osteoarthritis of knee or hip joint
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 VTc
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000414-39 Sponsor Protocol Number: BUP4203 Start Date*: 2004-08-10
    Sponsor Name:Mundipharma OY
    Full Title: A randomised, double-blind, placebo-controlled, parallel group, multicenter study to evaluate the long-term efficacy and safety of Norspan® versus placebo Norspan in subjects with chronic, moderate...
    Medical condition: Chronic, moderate to severe osteoarthritis pain of the hip and/or knee.
    Disease: Version SOC Term Classification Code Term Level
    5.1 10031161 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005596-90 Sponsor Protocol Number: NL51548.100.14 Start Date*: 2015-04-22
    Sponsor Name:St. Lucas Andreas Hospital
    Full Title: Comparison of femoral nerve block with posterior capsule infiltration versus anterior and posterior capsule infiltration after total knee replacement.
    Medical condition: patienst requiring total knee replacement for non-inflammatory osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000538-31 Sponsor Protocol Number: Neuroimpa2015 Start Date*: 2015-06-01
    Sponsor Name:Charité University medicine Berlin
    Full Title: NEUORIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the knee joint
    Medical condition: chronic arthritis of the knee joint effusion as part of spondyloarthritis (Assessments in SpondyloArthritis international Society, ASAS criteria), Rheumatoid Arthritis, RA (according to American Co...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10067624 Knee arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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