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Clinical trials for Pain.

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    5,490 result(s) found for: Pain.. Displaying page 9 of 275.
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    EudraCT Number: 2010-022025-15 Sponsor Protocol Number: 10-2-055 Start Date*: 2011-02-21
    Sponsor Name:MUMC
    Full Title: Intradiscal Methylene Blue Injection Treatment for Chronic Discogenic Low back pain A prospective Clinical Series followed by a Randomised Placebo-Controlled Clinical Trial
    Medical condition: The Randomized Clinical Trial (RCT) aims to prove the hypothesis that Intradiscal Methylene blue Injection is capable of better pain reduction than the best available treatment in patients sufferin...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000096-36 Sponsor Protocol Number: Botox-01 Start Date*: 2021-06-23
    Sponsor Name:Department of Dermatology and Copenhagen Wound Healing Center, Bispebjerg Hospital
    Full Title: The effect of subcutaneous injection of Botulinum Toxin A on chronic wound pain in lower extremities, a prospective exploratory study
    Medical condition: chronic wound pain and wound healing
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10049542 Wound pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-003171-21 Sponsor Protocol Number: LEV-2005 Start Date*: 2005-11-02
    Sponsor Name:Danish Pain Research Center
    Full Title: Effect of levetiracetam in spinal cord injury pain: a randomized, double-blind, placebo-controlled crossover study
    Medical condition: Neuropathic pain following spinal cord injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-003082-15 Sponsor Protocol Number: KTB-002 Start Date*: 2011-09-08
    Sponsor Name:Karen Toftdahl Bjørnholdt
    Full Title: High dose dexamethasone for pain following arthroscopic shoulder surgery: A randomised blinded clinical trial.
    Medical condition: Pain following arthroscopic shoulder surgery.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10040617 Shoulder pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009856-19 Sponsor Protocol Number: 42160443PAI2004AmINT-2 Start Date*: 2009-12-17
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 as Adjunctive Therapy in Subjects With Moderate to Severe Knee ...
    Medical condition: moderate to severe, chronic, knee or hip pain from osteoarthritis (OA) that is not adequately controlled by standard pain therapy
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10023477 Knee pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004341-24 Sponsor Protocol Number: KCT11/2017–BLOSSOM Start Date*: 2019-06-28
    Sponsor Name:Krka, d.d., Novo Mesto
    Full Title: Efficacy of pregabalin and duloxetine in patients with painful diabetic peripheral neuropathy (PDPN): the effect of pain on cognitive function, sleep and quality of life (BLOSSOM)
    Medical condition: The purpose of the trial is to assess the efficacy of Pregabalin Krka (pregabalin) and Dulsevia® (duloxetin) in patients with PDPN, investigate the effect of Pregabalin Krka and Dulsevia® on pain a...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed) PL (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2004-003752-19 Sponsor Protocol Number: OXN3401 Start Date*: 2005-02-01
    Sponsor Name:Mundipharma Research GmbH & Co.KG
    Full Title: A Randomized, Double-blind, Placebo- and Active-controlled, Double-dummy, Parallel Group Study to Determine the Safety and Efficacy of Oxycodone/Naloxone Prolonged-release Tablets in Subjects with ...
    Medical condition: Moderate to severe chronic pain of low back that requires around-the-clock opioid therapy.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10003988 pt
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) DK (Completed) SK (Completed) ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002743-10 Sponsor Protocol Number: A0081268 Start Date*: 2012-01-05
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, New York, NY 10017
    Full Title: A STUDY OF PREGABALIN IN THE TREATMENT OF SUBJECTS WITH PAINFUL DIABETIC PERIPHERAL NEUROPATHY WITH BACKGROUND TREATMENT OF NSAID FOR OTHER PAIN CONDITIONS
    Medical condition: PAINFUL DIABETIC PERIPHERAL NEUROPATHY
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10012683 Diabetic peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004181-18 Sponsor Protocol Number: SM-RS-2012 Start Date*: 2012-11-23
    Sponsor Name:Rigshospitalet; Department of Anaesthesia
    Full Title: The effect of dexamethasone in combination with paracetamol and ibuprofen as adjuvant, postoperative pain after herniated disk surgery
    Medical condition: Patients set to lumbar prolapse surgery in general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005656-26 Sponsor Protocol Number: 51748.094.15 Start Date*: 2015-10-14
    Sponsor Name:Westfriesgasthuis
    Full Title: Amitriptyline 10% and ketamine 10% cream in neuropathic pain: A randomised, double-blind, placebo-controlled cross-over pilot study with a three months open follow-up
    Medical condition: Patients with peripheral neuropathic pain or scar pain
    Disease: Version SOC Term Classification Code Term Level
    17.1 10040785 - Skin and subcutaneous tissue disorders 10049002 Scar pain PT
    17.1 100000004852 10029181 Nerve pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004317-18 Sponsor Protocol Number: TAP4 Start Date*: 2009-06-09
    Sponsor Name:Dept of Anaesthesia, University College Hospital, Galway
    Full Title: Comparison of continuous Lumbar Epidural (LEP) and Transversus Abdominis Plane (TAP) Blockade in the management of postoperative pain post abdominal surgery.
    Medical condition: Postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002223-42 Sponsor Protocol Number: A4091061 Start Date*: 2015-10-12
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF THE SUBCUTANEOUS ADMINISTRATION OF TANEZUMAB (PF-04383119) IN SUBJECTS WITH CANCER ...
    Medical condition: Metastatic Bone Pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10049038 Metastatic bone pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) GB (GB - no longer in EU/EEA) PL (Completed) ES (Completed) SK (Completed) HU (Completed) RO (Completed) FR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-005886-41 Sponsor Protocol Number: AUH-PAIN-01 Start Date*: 2022-06-29
    Sponsor Name:Aarhus University Hospital
    Full Title: Efficacy of Perioperative Long-acting Anesthesia by Local Infiltration Following Median Sternotomy - The PAIN Trial
    Medical condition: Acute postoperative pain after coronary bypass grafting surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004423-20 Sponsor Protocol Number: V00498TA301 Start Date*: 2013-01-10
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: STUDY OF EFFICACY AND SAFETY OF V0498 VERSUS PLACEBO IN ACUTE SORE THROAT PAIN
    Medical condition: Acute sore throat
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10049140 Pharyngotonsillitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) LV (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-002791-14 Sponsor Protocol Number: 1707-CL-0011 Start Date*: 2013-02-14
    Sponsor Name:Astellas Pharma Europe B.V.
    Full Title: A Randomized, Double-blind, Placebo-controlled, Phase 2 Study to Assess the Efficacy, Safety, and Dose-Response Relationship of ASP1707 in Subjects with Endometriosis Associated Pelvic Pain for 12 ...
    Medical condition: endometriosis associated pelvic pain
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004872 10014788 Endometriosis related pain LLT
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) BE (Completed) GB (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-001876-21 Sponsor Protocol Number: ACT11917 Start Date*: 2011-11-22
    Sponsor Name:sanofi-aventis recherche et développement
    Full Title: MULTINATIONAL, MULTICENTER, RANDOMIZED DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY OF EFFICACY AND SAFETY OF SAR292833 ADMINISTRATION FOR 4 WEEKS IN PATIENTS WITH CHRONIC PERIPHERAL NEUR...
    Medical condition: Neuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2012-002240-24 Sponsor Protocol Number: 214868-007 Start Date*: 2013-02-28
    Sponsor Name:Allergan Ltd.
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of the Safety and Efficacy of a Single Treatment of AGN-214868 in Patients With Postherpetic Neuralgia
    Medical condition: Postherpetic Neuralgia
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004779-64 Sponsor Protocol Number: ALMED-15-C2-054 Start Date*: 2016-12-20
    Sponsor Name:Air Liquide Santé International
    Full Title: Equimolar Mixture of Oxygen and Nitrous Oxide (EMONO) for the Treatment of Peripheral Neuropathic Pain: a Randomised, International, Multicentre, Placebo-Controlled, Phenotype-stratified Phase IIa ...
    Medical condition: Treatment Peripheral Neuropathic Pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2006-000397-71 Sponsor Protocol Number: kepp3 Start Date*: 2006-05-16
    Sponsor Name:Søren H. Sindrup, Department of Neurology, Odense University Hospital
    Full Title: Double-blind, randomised, placebo-controlled trial of levetiracetam for central neuropathic pain in patients with multiple sclerosis
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-001201-10 Sponsor Protocol Number: FEN-PPA-401 Start Date*: 2004-07-26
    Sponsor Name:JANSSEN-CILAG
    Full Title: Comparison of transdermal fentanyl PCA and IV morphine PCA in the management of post-operative pain control.
    Medical condition: Treatment of moderate to severe post-operative pain in subjects who have undergone an elective major abdominal or orthopaedic surgical procedure.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10056350 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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