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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    25,352 result(s) found. Displaying page 939 of 1,268.
    «« First « Previous 935  936  937  938  939  940  941  942  943  Next» Last»»
    EudraCT Number: 2012-001891-13 Sponsor Protocol Number: LeMLAR Start Date*: 2012-12-17
    Sponsor Name:University Hospital Essen
    Full Title: Lenalidomide in conjunction with methotrexate, leucovorin, cytarabine and rituximab for the treatment of relapsed or refractory CD20-positive aggressive lymphomas: an open-label, multicenter phase ...
    Medical condition: Relapsed or refractory CD20-positive aggressive B-cell lymphomas
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004637-16 Sponsor Protocol Number: SLAP Start Date*: 2009-04-28
    Sponsor Name:GISCAD
    Full Title: Folfiri as Second-Line chemotherapy for Advanced Pancreatic cancer: a GISCAD Phase II study
    Medical condition: Subjects enrolled in this study must have histologically confirmed locally advanced or metastatic pancreatic adenocarcinoma. They must have been received a first-line chemotherapy (one line only) w...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10013250 Disorder pancreas LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001641-33 Sponsor Protocol Number: PETAL-Studie Start Date*: 2007-07-25
    Sponsor Name:Universitätsklinikum Essen
    Full Title: Positronen-Emissionstomographie-gesteuerte Therapie aggressiver Non-Hodgkin-Lymphome (Positron emission tomography guided therapy of aggressive non-Hodgkin's lymphomas)
    Medical condition: Aggressive non-Hodgkin's lymphomas (first line therapy)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003239-13 Sponsor Protocol Number: PIMAT Start Date*: 2017-10-02
    Sponsor Name:Imperial College London JRC Office
    Full Title: Pharmacokinetics of Intramuscular Adrenaline in Food-Allergic Teenagers - does dose matter? The PIMAT study
    Medical condition: Anaphylaxis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000023018 10000664 Acute anaphylaxis LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-003331-10 Sponsor Protocol Number: HC03 Start Date*: 2017-10-16
    Sponsor Name:Leiden University
    Full Title: Acute effects of 40 mg cortisol on emotion and cognition.
    Medical condition: None.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-006602-24 Sponsor Protocol Number: PNC-2007 Start Date*: 2008-03-31
    Sponsor Name:Department of Pediatrics, Medical and Health Science Center, University of Debrecen
    Full Title: Relative adrenal insufficiency in children with pneumonia and sepsis. Efficacy of i.v. prednisolon for prevention of complication of pneumonia. A prospective, parallel-group, randomised trial.
    Medical condition: Severe complications of bacterial pneumonia i.e. abscess formation, empyema and sepsis in children. Supposed concomittant andrenal insuficiency is also planned to investigate.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2005-005207-42 Sponsor Protocol Number: 2005079 Start Date*: 2005-12-29
    Sponsor Name:Procter & Gamble Technical Centres Limited
    Full Title: A study to assess the efficacy of a combination of natural plant extracts in natural colds.
    Medical condition: Common Cold (nasopharyngitis), Upper Respiratory Tract Infection
    Disease: Version SOC Term Classification Code Term Level
    8.0 10028810 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000106-31 Sponsor Protocol Number: 2958 Start Date*: 2005-03-15
    Sponsor Name:Royal Liverpool University Hospital Clinical Trials 4th floor Linda McCartney Centre
    Full Title: IMPACT OF CYP2D6, SEROTONIN TRANSPORTER, 5HT1, 5HT2 AND 5HT3 RECEPTOR AND MU RECEPTOR GENE POLYMORPHISMS ON EFFICACY AND TOXICITY OF TRAMADOL
    Medical condition: OSTEOPOROSIS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-005166-58 Sponsor Protocol Number: AM-111-CL-15-01 Start Date*: 2017-10-12
    Sponsor Name:Auris Medical Inc.
    Full Title: Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment (ASSENT)
    Medical condition: Idiopathic sudden sensorineural hearing loss.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10013993 - Ear and labyrinth disorders 10061373 Sudden hearing loss PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001420-19 Sponsor Protocol Number: CINC280D2201 Start Date*: 2019-01-23
    Sponsor Name:Novartis Pharma AG
    Full Title: A phase II, multicenter, randomized, two-arm study of capmatinib (INC280, an oral MET inhibitor) and spartalizumab (PDR001, a PD-1 inhibitor) combination therapy versus docetaxel in pretreated adul...
    Medical condition: Non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059515 Non-small cell lung cancer metastatic PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) GB (Completed) BE (Completed) FR (Completed) GR (Completed) BG (Completed) NL (Completed) IT (Prematurely Ended) RO (Completed)
    Trial results: View results
    EudraCT Number: 2019-003713-33 Sponsor Protocol Number: 70903 Start Date*: 2020-03-02
    Sponsor Name:Princess Máxima Center for pediatric oncology
    Full Title: Diagnostic accuracy of neuroblastoma patient imaging with [18F]-mFBG PET-CT compared to [123]I-mIBG scanning
    Medical condition: Neuroblastoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029260 Neuroblastoma PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-002277-11 Sponsor Protocol Number: 20120123 Start Date*: 2015-06-23
    Sponsor Name:Amgen Inc
    Full Title: Double-blind, Randomized, Multicenter, Placebo-Controlled, Parallel Group Study to Characterize the Efficacy, Safety, and Tolerability of 24 Weeks of Evolocumab for Low Density Lipoprotein-Choleste...
    Medical condition: Heterozygous familial hypercholesterolaemia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10057079 Heterozygous familial hypercholesterolemia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) ES (Completed) IT (Completed) Outside EU/EEA GR (Completed) NL (Completed) GB (Completed) AT (Completed) HU (Completed) SI (Completed) PT (Completed) PL (Completed) NO (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2007-002380-27 Sponsor Protocol Number: ML21040 Start Date*: 2007-09-05
    Sponsor Name:Roche s.r.o.
    Full Title: A single arm open label study to assess the efficacy, safety and tolerability and of once-monthly administration of intravenous C.E.R.A. for the maintanance of haemoglobin levels in dialysis patien...
    Medical condition: Chronic renal anaemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058123 Renal anaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2004-000916-25 Sponsor Protocol Number: GIU-5-ASA1.2 MMx-01-03 Start Date*: 2004-09-28
    Sponsor Name:GIULIANI
    Full Title: A PHASE III PROSPECTIVE, DOUBLE-BLIND, RANDOMIZED, PARALLEL GROUPS, STUDY, TO ASSESS THE EFFECT OF 5-ASA MMx 1.2 g Tablets IN MAINTENANCE OF REMISSION OF LEFT-SIDED ULCERATIVE COLITIS
    Medical condition: TREATMENT OF ULCERATIVE COLITIS IN ACTIVE PHASE AND IN THE MAINTENANCE OF CLINICAL REMISSION
    Disease: Version SOC Term Classification Code Term Level
    6.1 10021972 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-006111-77 Sponsor Protocol Number: BMM-CZ-01 Start Date*: 2007-05-30
    Sponsor Name:Roche s.r.o.
    Full Title: Otevřená studie fáze II hodnotící bezpečnost a účinnost indukční analgetické léčby kyselinou ibandronovou (Bondronat) podávanou intravenózně po dobu 15 minut v dávce 6 mg 3 po sobě následující dny ...
    Medical condition: Mnohočetný myelom - analgetická léčba
    Disease: Version SOC Term Classification Code Term Level
    8.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2011-005879-16 Sponsor Protocol Number: GRC17536-201 Start Date*: 2012-06-11
    Sponsor Name:Glenmark Pharmaceuticals SA
    Full Title: A Phase II, 4 Week Randomized, Double-Blind, Parallel Group, Placebo Controlled Proof of Concept Study to Evaluate Efficacy, Safety and Tolerability of GRC 17536 in Patients with Painful Diabetic N...
    Medical condition: Pain associated with diabetic peripheral neuropathy (DPN).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10012683 Diabetic peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002432-40 Sponsor Protocol Number: 042/15 Start Date*: 2016-03-03
    Sponsor Name:ASSOCIAZIONE "LA NOSTRA FAMIGLIA" - SEZIONE SCIENTIFICA I.R.C.C.S. "E.MEDEA"
    Full Title: Safety and Efficacy of yIFN treatment in Friedreich ataxia
    Medical condition: FRDA is a progressive neurodegenerative disease inherited as recessive trait. It manifests itself usually in adolescence and affects various systems including the central and peripheral nervous sys...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10017374 Friedreich's ataxia PT
    20.0 10010331 - Congenital, familial and genetic disorders 10017374 Friedreich's ataxia PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001000-37 Sponsor Protocol Number: ML19070 Start Date*: 2006-09-19
    Sponsor Name:Roche Pharma AG
    Full Title: Efficacy and safety of rituximab in patients with rheumatoid arthritis
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004814-33 Sponsor Protocol Number: MOFA Start Date*: 2006-03-23
    Sponsor Name:Gesellschaft für Wissens- und Technologietransfer
    Full Title: Metabolic optimized fast track concept in general surgery
    Medical condition: Carcinoma of the colon or the liver scheduled for surgical resection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013976-38 Sponsor Protocol Number: COLO400BDE02T Start Date*: Information not available in EudraCT
    Sponsor Name:Charité Berlin, Department of rheumatology [...]
    1. Charité Berlin, Department of rheumatology
    2. Charité Berlin, department of rheumatology
    3. Charité Berlin, department of rheumatology
    Full Title: Phase II Trial of low-dose Sandimmun Optoral ® (Cyclosporine A) for the treatment of primary Sjögren's syndrome (pSS)
    Medical condition: Primary Sjögren's Syndrome
    Disease: Version SOC Term Classification Code Term Level
    12.1 10059142 Sjoegren's syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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