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Clinical trials for Activator

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    90 result(s) found for: Activator. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2008-003371-53 Sponsor Protocol Number: STROKE-FNUSA-01 Start Date*: 2008-08-08
    Sponsor Name:Fakultní nemocnice u svaté Anny
    Full Title: Acute Stroke Study of Optimized tPA Dosing in Correlation with Artery Status
    Medical condition: Patients with acute ischemic stroke with proven occlusion of major brain arteries demonstrated by transcranial ultrasound.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059620 Plasminogen activator inhibitor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000919-26 Sponsor Protocol Number: IVH05 Start Date*: 2005-07-29
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Trust [...]
    1. Newcastle upon Tyne Hospitals NHS Trust
    2. Johns Hopkins University
    Full Title: Phase II, randomized, pharmokinetic, dose finding, and dose frequency determination using rt-PA in intraventricular hemorrhage
    Medical condition: Intracerebral haemorrhage with intraventricular extension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2012-003289-42 Sponsor Protocol Number: 41399 Start Date*: 2012-12-21
    Sponsor Name:Academic Medical Center Amsterdam
    Full Title: Randomized Controlled Trial Investigating the Efficacy and Safety of Nebulized Heparin versus Placebo in Burn Patients with Inhalation Trauma
    Medical condition: Burn-associated inhalation trauma requiring intubation and mechanical ventilation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-001640-26 Sponsor Protocol Number: 132151 Start Date*: 2020-04-17
    Sponsor Name:University College London
    Full Title: A pilot, open label, phase II clinical trial of nebulised recombinant tissue-Plasminogen Activator (rtPA)in patients with COVID-19 ARDS: The Plasminogen Activator COVID-19 ARDS (PACA) trial
    Medical condition: Acute respiratory distress syndrome (ARDS) caused by COVID-19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-000377-40 Sponsor Protocol Number: MST-188-07 Start Date*: 2014-11-13
    Sponsor Name:Mast Therapeutics, Inc.
    Full Title: Evaluation of MST-188 in Acute Lower Limb Ischemia: A Phase 2 Randomized Double-Blind, Placebo-Controlled, Multi-Center Clinical Trial Evaluating the Safety and Efficacy Of MST-188 in Subjects with...
    Medical condition: Acute Lower Limb Ischemia
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004866 10066920 Leg ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001317-28 Sponsor Protocol Number: ABBA-2 Start Date*: 2015-07-30
    Sponsor Name:UMC Utrecht
    Full Title: A B2-agonist as a CFTR activator in CF - Part 2
    Medical condition: Cystic fibrosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001398-44 Sponsor Protocol Number: PR 2006-04 Start Date*: 2006-06-13
    Sponsor Name:Barts and The London NHS Trust
    Full Title: The use of Peroxisome Proliferator Activator Receptor Agonists in the management of Androgen Independent Prostate Cancer
    Medical condition: The use of Peroxisome Proliferator Activator Receptor Agonists in the management of Androgen Independent Prostate Cancer. Open-labeled, non-randomised clinical trial in patients with androgen indep...
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000057-37 Sponsor Protocol Number: ABBA-2014 Start Date*: 2014-04-30
    Sponsor Name:University Medical Centre Utrecht
    Full Title: A B2-agonist as a CFTR activator in CF
    Medical condition: Cystic Fibrosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001218-42 Sponsor Protocol Number: 177/2004/U/Sper Start Date*: 2005-01-17
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Clinical role of PPAR gamma activator (pioglitazone) in reducing the gastric phlogosis in patiens with istological gastritis.
    Medical condition: Treatment of patients with gastric phlogosis (infected by Helicobacter pylori)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017904 Gastroenteritis helicobacter LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-002478-30 Sponsor Protocol Number: FLUSH Start Date*: 2013-06-05
    Sponsor Name:Leiden University Medical Center
    Full Title: Arterial perfusion with t-PA in donation after cardiac death (DCD) to reduce the incidence of non-anastomotic biliary strictures after orthotopic liver transplantation
    Medical condition: Biliary strictures after orthotopic liver transplantation caused by microthrombi in the donorliver during procurement
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018637-21 Sponsor Protocol Number: 1 Start Date*: 2013-11-20
    Sponsor Name:Universitätsklinikum Schleswig-Holstein UKSH
    Full Title: Intravitreal Injection of Lucentis (Ranibizumab) after Pars Plana Vitrectomy and Subretinal Application of Recombinant Tissue Plasminogen Activator (rtPA) in Patients with Acute Submacular Hemorrha...
    Medical condition: exsudative age-related macular degeneration with acut submacular hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004853 10055305 Macula lutea hemorrhage LLT
    16.1 100000004853 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001070-27 Sponsor Protocol Number: EP-PAE Metalyse Start Date*: 2005-07-07
    Sponsor Name:Division of Angiology Graz
    Full Title: Open, randomised, monosite pilot trial for comparison of thrombolytic efficacy of tenecteplase and alteplase in patients with acute pulmonary embolism
    Medical condition: Patients with acute pulmonary embolism and indication for thrombolytic therapy are included in the study
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019760-36 Sponsor Protocol Number: T05018-2004 Start Date*: 2010-11-22
    Sponsor Name:Grifols Therapeutics, Incorporated
    Full Title: A Phase 2, Randomized, Open-label (with Blinded Plasminogen Activator and Placebo Control Groups) Study to Evaluate the Effects of Different Intra-thrombus Infusion Regimens of Plasmin (Human) Comp...
    Medical condition: acute peripheral arterial occlusion
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10057525 Peripheral artery occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) HU (Prematurely Ended) DE (Prematurely Ended) BE (Completed) ES (Prematurely Ended) CZ (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-003176-38 Sponsor Protocol Number: 135.312 Start Date*: 2006-05-22
    Sponsor Name:Boehringer Ingelheim Pharma Ges mbH
    Full Title: A placebo controlled trial of alteplase (rt-PA) in acute ischemic hemispheric stroke where thrombolysis is initiated between 3 and 4 hours 30 minutes after stroke onset
    Medical condition: Ischemic stroke 3 and 4 hours 30 minutes before treatment
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-016007-39 Sponsor Protocol Number: I2Q-MC-GMAJ Start Date*: 2010-02-15
    Sponsor Name:Eli Lilly and Company
    Full Title: A 12-Week, Phase 2, Randomized, Double-Blind, Active-Controlled Study of LY2599506 Given as Monotherapy or in Combination with Metformin in Patients with Type 2 Diabetes Mellitus
    Medical condition: Type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) ES (Completed) AT (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-006006-22 Sponsor Protocol Number: ICH01 Start Date*: 2009-01-14
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Trust [...]
    1. Newcastle upon Tyne Hospitals NHS Trust
    2. Johns Hopkins University
    Full Title: Minimally Invasive Surgery plus rt-PA for ICH Evacuation
    Medical condition: intracerebral hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10062025 Intracerebral haematoma evacuation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002818-12 Sponsor Protocol Number: ICH02 Start Date*: 2014-06-13
    Sponsor Name:The John Hopkins University
    Full Title: A phase III, randomized, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral haemorrhage.
    Medical condition: Spontaneous supratentorial intracerebral haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10062025 Intracerebral haematoma evacuation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003859-12 Sponsor Protocol Number: 12-027 Start Date*: 2013-07-19
    Sponsor Name:RWTH Aachen University for the Medical Faculty, represented by Clinical Trial Center Aachen (CTC-A)
    Full Title: Linagliptin as a modulator of vascular inflammation in patients with type 2 diabetes mellitus
    Medical condition: patients with type 2 diabetes mellitus and vascular inflammation
    Disease: Version SOC Term Classification Code Term Level
    17.0 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    17.0 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-000238-36 Sponsor Protocol Number: IST-399 Start Date*: 1999-10-05
    Sponsor Name:The University of Edinburgh & Lothian Health Board
    Full Title: Third International Stroke Trial (IST-3) of thrombolysis for acute ischaemic stroke
    Medical condition: Acute ischaemic stroke refers to strokes caused by thrombosis or embolism and accounts for 85% of all strokes.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023027 Ischaemic stroke NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002760-41 Sponsor Protocol Number: CL2-RTCCAR-001 Start Date*: 2017-09-18
    Sponsor Name:institute de Recherches Internacionales Servier (promotor internacional)
    Full Title: Assessment of Active Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa) plasma kinetics in Patients at acute stage of Ischemic Stroke: Prospective, Multicentre, Open, Non-randomised, Biomarker Study
    Medical condition: Acute Ischemic Stroke
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000013700 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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