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Clinical trials for Allopurinol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    85 result(s) found for: Allopurinol. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2016-001638-84 Sponsor Protocol Number: 16-07 Start Date*: 2016-07-08
    Sponsor Name:Meander Medical Center
    Full Title: Thiopurines with Low Dose Allopurinol: a prospective one way cross-over study
    Medical condition: Crohn's disease & Colitis Ulcerosa
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-001436-22 Sponsor Protocol Number: 2012CV07 Start Date*: 2013-08-06
    Sponsor Name:University of Dundee/NHS Tayside
    Full Title: Does ALlopurinol regress lefT ventricular hypertrophy in End stage REnal Disease: The ALTERED study
    Medical condition: Renal failure and left ventricular hypertrophy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020662-23 Sponsor Protocol Number: 2009CV16 Start Date*: 2010-09-08
    Sponsor Name:University of Dundee [...]
    1. University of Dundee
    2. NHS Tayside
    Full Title: Allopurinol as a possible oxygen sparing agent during exercise in peripheral arterial disease
    Medical condition: Peripheral arterial disease
    Disease: Version SOC Term Classification Code Term Level
    13.0 10067825 Peripheral arterial disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004996-35 Sponsor Protocol Number: 2010CV30 Start Date*: 2011-12-23
    Sponsor Name:University of Dundee
    Full Title: Allopurinol as a possible new therapy for acute coronary syndromes: The Next Steps
    Medical condition: Acute coronary syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001669-33 Sponsor Protocol Number: tsa1 Start Date*: 2005-12-09
    Sponsor Name:Greater Glasgow NHS Health Board / University of Glasgow co-sponsorship
    Full Title: New therapeutic targets in stroke prevention: the effect of allopurinol on the cerebral vasculature of patients with subcortical stroke
    Medical condition: Subcortical Ischaemic Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-003767-29 Sponsor Protocol Number: RDEA594-302 Start Date*: 2012-06-04
    Sponsor Name:Ardea Biosciences, Inc.
    Full Title: A Phase 3 Randomized, Double-Blind, Multicenter, Placebo- Controlled, Combination Study to Evaluate the Efficacy and Safety of Lesinurad and Allopurinol Compared to Allopurinol Alone in Subjects w...
    Medical condition: Gout
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10018627 Gout PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed) PL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-004079-11 Sponsor Protocol Number: D5495C00002 Start Date*: 2019-06-28
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase 2b, Multicentre, Randomised, Double-blind, Placebo-controlled Study of Verinurad and Allopurinol in Patients with Chronic Kidney Disease and Hyperuricaemia
    Medical condition: Chronic kidney disease and hyperuricaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed) CZ (Completed) ES (Ongoing) IT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2019-004862-16 Sponsor Protocol Number: D5496C00005 Start Date*: 2020-06-03
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase 2, Multicentre, Double-Blind, Placebo and Active Control Efficacy and Safety Study to Evaluate Verinurad combined with Allopurinol in Heart Failure with Preserved Ejection Fraction
    Medical condition: Heart Failure Patients with Preserved Ejection Fraction (HFpEF) and hyperuricaemia
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004849 10076396 Heart failure with preserved ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BG (Completed) PL (Completed) SK (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-004224-23 Sponsor Protocol Number: TSAIMT01 Start Date*: 2009-03-13
    Sponsor Name:University of Glasgow / NHS Greater Glasgow and Clyde
    Full Title: The effect of allopurinol on carotid ultrasound intima-media thickness and markers of endothelial function in patients with recent stroke - a pilot study.
    Medical condition: Ischaemic stroke or transient ischaemic attack (TIA) (ICD Classification Code I63.0-9 and G45.0-1).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061256 Ischaemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-004122-18 Sponsor Protocol Number: 2012GR12 Start Date*: 2014-12-12
    Sponsor Name:University of Dundee, Tayside Clinical Trials Unit
    Full Title: A Prospective Study to Evaluate the Effect of Allopurinol on Muscle Energetics in Older People with Impaired Physical Function.
    Medical condition: FUNCTIONAL IMPAIRMENT
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004867 10065629 Decreased exercise endurance LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003081-42 Sponsor Protocol Number: Jus002 Start Date*: 2005-10-06
    Sponsor Name:University of DUndee
    Full Title: EXPLORING THE THERAPEUTIC POTENTIAL OF XANTHINE OXIDASE INHIBITORS IN CORONARY ARTERY DISEASE
    Medical condition: Ishaemic heart disease; Angina, acute myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001084-27 Sponsor Protocol Number: APAC Start Date*: 2006-06-16
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALI GALLIERA
    Full Title: Phase I/II study of prevention of Colorectal Cancer CRC with Allopurinol in High-Risk Subjects
    Medical condition: CHEMOPREVENTION OF COLORECTAL CANCER
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048832 Colon adenoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001670-27 Sponsor Protocol Number: CSO1 Start Date*: 2005-11-14
    Sponsor Name:Greater Glasgow NHS Health Board / University of Glasgow co-sponsorship
    Full Title: Reversibility of cerebrovascular endothelial dysfunction in diabetes: the role of allopurinol.
    Medical condition: Type Two Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002293-54 Sponsor Protocol Number: Apex01version6 Start Date*: 2007-11-29
    Sponsor Name:University of Dundee
    Full Title: The APEX Trial: Effects of Allopurinol on Coronary and Peripheral Endothelial Function in Patients with Cardiac Syndrome X
    Medical condition: Patients with cardiac syndrome X (typical anginal-like chest pain and normal coronary arteriograms)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003409-33 Sponsor Protocol Number: AllopurinolALL3.1 Start Date*: 2016-12-09
    Sponsor Name:Västra Götaland Regionen
    Full Title: Optimizing 6-mercaptopurine therapy in pediatric acute lymphoblastic leukemia by using allopurinol. Clinical study in children 1-19 years on maintenance therapy for acute lymphoblastic leukemia.
    Medical condition: Acute lymphoblastic leukemia diagnosed at age 0-18 in children
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014660-19 Sponsor Protocol Number: RDEA594-203 Start Date*: 2009-12-09
    Sponsor Name:Ardea Biosciences, Inc.
    Full Title: Randomized, Double-Blind, Multicenter, Placebo-Controlled, Combination Study to Evaluate the Safety, Efficacy and Potential Pharmacokinetic Interaction of RDEA594 and Allopurinol in Gout Patients w...
    Medical condition: Gout
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10018627 Gout PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002453-65 Sponsor Protocol Number: ALLO-401 Start Date*: 2012-01-18
    Sponsor Name:Ardea Biosciences, Inc.
    Full Title: Long-term Allopurinol Safety Study Evaluating Outcomes in Gout Patients (LASSO)
    Medical condition: Gout
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10018627 Gout PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-000164-42 Sponsor Protocol Number: 2016RC01 Start Date*: 2016-08-17
    Sponsor Name:Tayside Medical Sciences Centre on behalf of University of Dundee
    Full Title: JAB02 Repurposing allopurinol as a novel anti-inflammatory treatment for persistent allergic asthma.
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10001705 Allergic asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-000619-16 Sponsor Protocol Number: EC10-060 Start Date*: 2011-06-08
    Sponsor Name:Fundación Investigación Biomedica. Hospital Clinico San Carlos
    Full Title: Identification of the effect of allopurinol treatment on platelets from diabetic patients with stable coronary ischemic disease and aspirin resistance. XUE Study. Estudio cruzado para valorar el...
    Medical condition: Hipótesis: el tratamiento con alopurinol (600 mg/día) en pacientes diabéticos resistentes a aspirina con enfermedad coronaria establecida podría favorecer el efecto antiplaquetario de la aspirina e...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001883-23 Sponsor Protocol Number: 2011CV08 Start Date*: 2011-08-03
    Sponsor Name:University of Dundee
    Full Title: FAST- Febuxostat versus Allopurinol Streamlined Trial A prospective, randomised, open-label, blinded endpoint (PROBE) clinical trial evaluating long term cardiovascular safety of febuxostat in co...
    Medical condition: Chronic symptomatic hyperuricaemic
    Disease: Version SOC Term Classification Code Term Level
    17.0 10027433 - Metabolism and nutrition disorders 10018627 Gout PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DK (Completed) FI (Prematurely Ended) SE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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