- Trials with a EudraCT protocol (27)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
27 result(s) found for: Apolipoproteins.
Displaying page 1 of 2.
EudraCT Number: 2021-002687-41 | Sponsor Protocol Number: TA-8995-AD-1 | Start Date*: 2021-12-09 |
Sponsor Name:NewAmsterdam Pharma BV | ||
Full Title: A Phase 2a, Proof-of-Concept, Open-Label Study to Evaluate the Pharmacodynamics, Pharmacokinetics, and Safety of Obicetrapib in Patients with Early Alzheimer’s Disease (Hetero/Homozygote APOE4 Carr... | ||
Medical condition: Alzheimer's disease | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2010-023742-79 | Sponsor Protocol Number: AEG 733-012 | Start Date*: 2011-03-25 | |||||||||||
Sponsor Name:AEGERION PHARMACEUTICALS | |||||||||||||
Full Title: A Phase III, Long Term, Open Label, Follow on Study of Microsomal Triglyceride Transfer Protein (MTP) Inhibitor ‘lomitapide’ (AEGR-733) in Patients with Homozygous Familial Hypercholesterolemia | |||||||||||||
Medical condition: Homozygous Familial Hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-007058-36 | Sponsor Protocol Number: 733-005 | Start Date*: 2009-06-25 | |||||||||||
Sponsor Name:Aegerion Pharmaceuticals | |||||||||||||
Full Title: A Phase III Study of Microsomal Triglyceride Transfer Protein (MTP) Inhibitor AEGR-733 in Patients with Homozygous Familial Hypercholesterolemia on Current Lipid-lowering Therapy | |||||||||||||
Medical condition: Homozygous Familial Hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-003815-37 | Sponsor Protocol Number: MDCO-PCS-16-01 | Start Date*: 2017-02-24 | |||||||||||
Sponsor Name:Novartis Pharma AG | |||||||||||||
Full Title: An open label, active comparator extension trial to assess the effect of long term dosing of inclisiran and evolocumab given as subcutaneous injections in subjects with high cardiovascular risk and... | |||||||||||||
Medical condition: Hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) NL (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-000882-36 | Sponsor Protocol Number: PAD20001 | Start Date*: 2004-08-05 |
Sponsor Name:GlaxoSmithKine Research & Development Limited | ||
Full Title: A multi-centre, two-staged with interim analysis, parallel, randomised, double blind, placebo-controlled, dose ranging study of the safety, tolerability, and effects on plasma high-density lipoprot... | ||
Medical condition: Treatment of dyslipidaemia | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: SE (Completed) FI (Completed) LT (Completed) DK (Completed) | ||
Trial results: View results |
EudraCT Number: 2006-002911-28 | Sponsor Protocol Number: PAD107271 | Start Date*: 2006-07-29 | |||||||||||
Sponsor Name:GlaxoSmithKline R&D | |||||||||||||
Full Title: A multicentre, randomized, double-blind, parallel-group, placebo-controlled, dose-ranging study to evaluate the efficacy, safety and tolerability of once daily oral dosing of GW501516 (2.5 mg, 5 mg... | |||||||||||||
Medical condition: primary hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) CZ (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-005473-36 | Sponsor Protocol Number: Dezember2014Version2 | Start Date*: Information not available in EudraCT |
Sponsor Name:Universitätsklinikum Freiburg | ||
Full Title: Modeling of lipoprotein in patients with familial hypercholesterolemia compared to healthy subjects | ||
Medical condition: familial hypercholesterolemia | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male | |
Trial protocol: DE (Completed) | ||
Trial results: View results |
EudraCT Number: 2011-001023-21 | Sponsor Protocol Number: DRL-17822/CD/004 | Start Date*: 2011-06-30 | |||||||||||
Sponsor Name:DR. REDDY'S LABORATORIES LIMITED | |||||||||||||
Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate Efficacy, Safety and Tolerability of DRL-17822 in Patients with Type II Hyperlipidemia | |||||||||||||
Medical condition: Hyperlipidemia Type II | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-002472-30 | Sponsor Protocol Number: MDCO-PCS-17-03 | Start Date*: 2018-01-04 | |||||||||||
Sponsor Name:The Medicines Company | |||||||||||||
Full Title: A PLACEBO-CONTROLLED, DOUBLE-BLIND, RANDOMIZED TRIAL TO EVALUATE THE EFFECT OF 300 MG OF INCLISIRAN SODIUM GIVEN AS SUBCUTANEOUS INJECTIONS IN SUBJECTS WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEM... | |||||||||||||
Medical condition: Hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) ES (Completed) CZ (Completed) SE (Completed) DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-001846-90 | Sponsor Protocol Number: MDCO-PCS-17-08 | Start Date*: 2017-12-12 | |||||||||||
Sponsor Name:The Medicines Company | |||||||||||||
Full Title: A PLACEBO-CONTROLLED, DOUBLE-BLIND, RANDOMIZED TRIAL TO EVALUATE THE EFFECT OF 300 MG OF INCLISIRAN SODIUM GIVEN AS SUBCUTANEOUS INJECTIONS IN SUBJECTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (... | |||||||||||||
Medical condition: Hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) HU (Completed) GB (Completed) CZ (Completed) NL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2010-022529-14 | Sponsor Protocol Number: WC25501 | Start Date*: 2011-02-04 | |||||||||||
Sponsor Name:F.Hoffmann-La Roche | |||||||||||||
Full Title: A phase III, double-blind, randomized, placebo-controlled, multi-center study evaluating the efficacy and safety of dalcetrapib on lipids, lipoproteins, apolipoproteins and markers of CV risk in pa... | |||||||||||||
Medical condition: Coronary Heart Disease | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: CZ (Completed) GB (Completed) NL (Completed) | |||||||||||||
Trial results: Removed from public view |
EudraCT Number: 2004-000139-27 | Sponsor Protocol Number: A509 1018 | Start Date*: 2004-09-14 | |||||||||||
Sponsor Name:Pfizer AB | |||||||||||||
Full Title: A Phase 3, Double-Blind, Placebo-Controlled, Randomized, Parallel Group, Multicenter Study of the Efficacy, Safety, and Tolerability of Fixed Combination Torcetrapib/Atorvastatin Administered Orall... | |||||||||||||
Medical condition: Mixed dyslipidemia (Frederickson Types IIa and IIb) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2018-002911-80 | Sponsor Protocol Number: LOCHNES | Start Date*: 2018-12-18 | |||||||||||
Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA POLICLINICO "PAOLO GIACCONE" DI PALERMO | |||||||||||||
Full Title: Open-label study to evaluate the safety, tolerability, and efficacy of LOmitapide for the treatment of patients with Familial CHylomicroNEmia Syndrome | |||||||||||||
Medical condition: Familial Chylomicronemia Syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-005418-45 | Sponsor Protocol Number: HCQCVDRASLE-1.1 | Start Date*: 2015-05-04 |
Sponsor Name:Christine Bengtsson [...] | ||
Full Title: Improved cardiovascular risk factors and inflammatory markers in Rheumatoid Arthritis and Systemic Lupus Erythematosus? New aspects of Hydroxychloroquine – an interventional study (HCQCVDRASLE) | ||
Medical condition: Rheumatoid Arthritis and Systemic Lupus Erythematosus | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: SE (Completed) | ||
Trial results: View results |
EudraCT Number: 2011-004308-39 | Sponsor Protocol Number: R727-CL-1018 | Start Date*: 2012-02-29 |
Sponsor Name:Regeneron Pharmaceuticals, Inc. | ||
Full Title: A Phase 2 Pilot Study with a Randomized Double-Blind Treatment Phase to Evaluate the Pharmacodynamics and Safety of REGN727 in Patients with Autosomal Dominant Hypercholesterolemia and Gain-of-Func... | ||
Medical condition: Hypercholesterolemia | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: FR (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-003772-74 | Sponsor Protocol Number: MDCO-PCS-15-01 | Start Date*: 2015-12-16 | |||||||||||
Sponsor Name:The Medicines Company | |||||||||||||
Full Title: A placebo-controlled, double-blind, randomized trial to compare the effect of different doses of ALN-PCSSC given as single or multiple subcutaneous injections in subjects with high cardiovascular r... | |||||||||||||
Medical condition: Hypercholesterolemia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) DE (Completed) NL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-003908-61 | Sponsor Protocol Number: Vasc-UMCU-10B | Start Date*: 2008-12-09 | |||||||||||
Sponsor Name:University Medical Center Utrecht | |||||||||||||
Full Title: A MULTICENTER, DOUBLE-BLIND, RANDOMIZED, 2-PERIOD, CROSSOVER STUDY TO COMPARE THE EFFECTS OF EZETIMIBE/SIMVASTATIN (10 MG/10 MG) COMBINATION TABLET VERSUS SIMVASTATIN 80 MG TABLET ON POSTPRANDIAL A... | |||||||||||||
Medical condition: Metabolic syndrome as defined by the ATP III criteria | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-004365-27 | Sponsor Protocol Number: EDP-305-101 | Start Date*: 2018-12-17 | |||||||||||
Sponsor Name:Enanta Pharmaceuticals Inc. | |||||||||||||
Full Title: A Phase 2 Dose Ranging, Randomized, Double Blind, and Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects with Non-Alcoholic Steatohep... | |||||||||||||
Medical condition: Non-alcoholic Steatohepatitis (NASH) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-002070-36 | Sponsor Protocol Number: GLU-005 | Start Date*: 2004-12-22 | |||||||||||
Sponsor Name:Metcon Medicin AB | |||||||||||||
Full Title: Efficacy of MM005-Granulae as prophylaxis for nocturnal hypoglycemia in insulin treated Type 1 diabetic subjects. A double-blind, randomized, placebo-controlled phase II multi-center study in three... | |||||||||||||
Medical condition: Diabetes type I | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-001628-45 | Sponsor Protocol Number: 2.0 | Start Date*: 2015-09-09 |
Sponsor Name:Dep. of Medical Cell Biology Uppsala University | ||
Full Title: A parallel, double-blinded, randomized, 6 months, two arms study with lifestyle intervention and exenatide 2 mg once weekly or lifestyle intervention and placebo in adolescents with obesity to expl... | ||
Medical condition: Obesity in adolescents | ||
Disease: | ||
Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |
Trial protocol: SE (Completed) | ||
Trial results: (No results available) |
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