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Clinical trials for Conscious sedation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    19 result(s) found for: Conscious sedation. Displaying page 1 of 1.
    EudraCT Number: 2014-005170-11 Sponsor Protocol Number: UCLDexAlf1 Start Date*: 2015-01-26
    Sponsor Name:Cliniques universitaires Saint Luc
    Full Title: Can we get conscious sedation in optimal safety conditions in an emergency department, by combining dexmedetomidine with alfentanil?
    Medical condition: Adult over 18 years, of both sexes, for which a procedural sedation is needed in emergency room.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005443-26 Sponsor Protocol Number: 9813 Start Date*: 2006-03-03
    Sponsor Name:Greater Glasgow Health Board
    Full Title: Effect site controlled, reaction time safeguarded, patient maintained sedation with propofol in Healthy Volunteers
    Medical condition: IMP will be used to provide conscious sedation for healthy volunteers. No medical condition
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-005758-39 Sponsor Protocol Number: 9812/A Start Date*: 2006-08-16
    Sponsor Name:Greater Glasgow Health Board
    Full Title: Effect site controlled, reaction time safeguarded, patient maintained sedation with Propofol A) in oral surgery patients B) in general dentistry patients C) in colonoscopy patients
    Medical condition: No specific medical condition. IMP will be used to provide conscious sedation for patients undergoing potentially unpleasant procedures including dentistry and colonoscopy.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004890-26 Sponsor Protocol Number: R0115 Start Date*: 2005-01-07
    Sponsor Name:HULL AND EAST YORKSHIRE NHS TRUST
    Full Title: RANDOMISED CONTROLLED TRIAL OF SEDATION FOR COLONOSCOPY-ENTONOX VERSUS MIDAZOLAM/ FENTANYL
    Medical condition: COLONOSCOPY
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001567-37 Sponsor Protocol Number: KUKIDEX-2 Start Date*: 2016-11-24
    Sponsor Name:University Medical Center Groningen
    Full Title: Efficacy of single dose intranasal dexmedetomidine for conscious sedation in dental practice in dentophobic uncooperative patients with intellectual disability.
    Medical condition: dentophobia intellectual disability
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002243-17 Sponsor Protocol Number: DEXCOM Start Date*: 2014-10-24
    Sponsor Name:Clínica Universidad de Navarra/Universidad de Navarra
    Full Title: Conscious sedation for procedures in Dental and Minor Maxillofacial Surgery Unit: optimization of the dexmedetomidine dose (Dexdor®).
    Medical condition: Sedation for procedures in Dental and Minor Maxillofacial Surgery Unit
    Disease: Version SOC Term Classification Code Term Level
    17.0 10042613 - Surgical and medical procedures 10054806 Maxillofacial operation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-003887-48 Sponsor Protocol Number: R0239 Start Date*: 2005-12-21
    Sponsor Name:HULL AND EAST YORKSHIRE NHS TRUST
    Full Title: Randomised Controlled Trial of patient-controlled sedation for colonoscopy: Entonox versus target-controlled infusion of propofol
    Medical condition: COLONOSCOPY- NO SPECIFIC MEDICAL CONDITION
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003749-15 Sponsor Protocol Number: RES/0186/7211 Start Date*: 2006-02-02
    Sponsor Name:Merck, Sharp & Dohme-Clinical Pharmacology,Europe
    Full Title: Investigation of the effectiveness of oral lorazepam in managing preoperative dental anxiety in phobic dental patients-A pilot study
    Medical condition: Pre operative dental anxiety, in phobic dental patients.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001496-21 Sponsor Protocol Number: LOC-2013 Start Date*: 2013-06-18
    Sponsor Name:Harry Scheinin
    Full Title: The Neural Mechanisms of Anesthesia and Human Consciousness
    Medical condition: No medical condition or disease involved. The study subjects are healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002782-37 Sponsor Protocol Number: ENT05 Start Date*: 2005-11-17
    Sponsor Name:Heart of England NHS Foundation Trust
    Full Title: A Randomised Trial of Inhaled Entonox Plus Local Anaesthesia Versus Intravenous Midazolam Plus Local Anaesthesia To Improve Pain Control During Bone Marrow Biopsy
    Medical condition: This study will involve a group of patients requiring diagnostic bone marrow aspiration and biopsy. The reasons for these will include haematological abnormalities of the blood count , which may be...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002495-18 Sponsor Protocol Number: SG2006/1 Start Date*: 2007-04-08
    Sponsor Name:Wrightington, Wigan and Leigh NHS Trust
    Full Title: The use of ketamine in combination with midazolam for the induction of conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP).
    Medical condition: The study will not investigate any specific disease, but rather the sedation techniques used for endoscopic retrograde cholangiopancreatography, a form of endoscopy which can be used to diagnose an...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10014802 Endoscopic retrograde cholangiopancreatography LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003612-30 Sponsor Protocol Number: 0904HELIOX Start Date*: 2005-11-23
    Sponsor Name:Barts and the London NHS Trust
    Full Title: A comparison of Helium-oxygen mixture (Heliox) with an oxygen-air mixture in reducing the work of breathing during weaning from mechanical ventilation.
    Medical condition: Patients admitted to the intensive care unit who are in the recovery phase of their illness and are weaning from mechanical ventilation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003438-17 Sponsor Protocol Number: 05/Q1606/143 Start Date*: 2005-11-07
    Sponsor Name:Oxford Radcliffe Hospitals NHS Trust
    Full Title: SimSepT: Simvastatin and severe sepsis in the ICU
    Medical condition: Severe sepsis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-004846-28 Sponsor Protocol Number: NL60118.058.17 Start Date*: 2018-11-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Efficacy of Sodium Oxybate to promote sleep in the ICU: A randomized controlled trial
    Medical condition: Sleep disturbance
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002584-27 Sponsor Protocol Number: AC-054-301 Start Date*: 2007-11-07
    Sponsor Name:Actelion Pharmaceuticals Ltd.
    Full Title: A prospective, multi-center, double-blind, randomized, placebo-controlled, parallel-group study to assess the efficacy and safety of clazosentan in reducing vasospasm-related morbidity and all-caus...
    Medical condition: Indication: Aneurysmal subarachnoid hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042318 Subarachnoid haemorrhage NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) FI (Completed) SE (Completed) DE (Completed) AT (Completed) DK (Completed) ES (Completed) CZ (Completed) IT (Completed) SI (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2008-006785-29 Sponsor Protocol Number: AC-054-302 Start Date*: 2009-09-15
    Sponsor Name:Actelion Pharmaceuticals Ltd.
    Full Title: A prospective, multi-center, double-blind, randomized, placebo-controlled, parallel-group study to assess the efficacy and safety of clazosentan in reducing vasospasm-related morbidity and all-caus...
    Medical condition: Indication: Subarachnoid aneurysmal hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    11 10042316 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) DK (Prematurely Ended) FI (Prematurely Ended) AT (Prematurely Ended) BE (Completed) CZ (Completed) FR (Completed) DE (Completed) SI (Prematurely Ended) ES (Prematurely Ended) HU (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004469-28 Sponsor Protocol Number: MR311-4501 Start Date*: 2018-03-01
    Sponsor Name:MUNDIPHARMA
    Full Title: Multicentre, randomised, double-blind study assessing the efficacy and safety of Penthrox® combined with a standard analgesia (SoC) in comparison to a placebo combined with a standard analgesia (So...
    Medical condition: Emergency relief of moderate to severe pain associated with trauma in conscious adult patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10044461 Trauma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004355-37 Sponsor Protocol Number: B5301001 Start Date*: 2013-06-04
    Sponsor Name:Pfizer Inc.
    Full Title: A PHASE 2, RANDOMIZED, DOUBLE-BLIND, WITHIN-SUBJECT, PLACEBO CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-06473871 IN REDUCING HYPERTROPHIC SKIN SCARRING
    Medical condition: Hypertrophic skin scarring
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) ES (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-002548-15 Sponsor Protocol Number: VTS301 Start Date*: 2015-12-01
    Sponsor Name:Vtesse LLC, a Mallinckrodt Pharmaceutical Company
    Full Title: A Phase 2b/3 Prospective, Randomized, Double-blind, Sham-controlled Trial of VTS-270 (2-hydroxypropyl-β-cyclodextrin) in Subjects with Neurologic Manifestations of Niemann-Pick Type C1 (NPC1) Disease
    Medical condition: Neurologic Manifestations of Niemann-Pick Type C1 (NPC1) Disease
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) GB (GB - no longer in EU/EEA) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
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