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Clinical trials for Current of injury

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    126 result(s) found for: Current of injury. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2009-015532-14 Sponsor Protocol Number: EMR700692-003 Start Date*: 2010-01-22
    Sponsor Name:Merck Serono S.A. - Geneva
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group phase II trial to investigate the efficacy and safety of weekly intra-articular (i.a.) injections of 10, 30, and 100 µg o...
    Medical condition: Knee Cartilage Injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) SI (Completed) BG (Prematurely Ended) AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-001227-31 Sponsor Protocol Number: NISCI Start Date*: 2019-06-19
    Sponsor Name:University Zurich, University Hospital Balgrist, Spinal Cord Injury Center
    Full Title: Antibodies against Nogo-A to enhance plasticity, regeneration and functional recovery after acute spinal cord injury
    Medical condition: spinal cord injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10041554 Spinal cord injury cervical PT
    20.1 10022117 - Injury, poisoning and procedural complications 10041552 Spinal cord injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2006-004396-35 Sponsor Protocol Number: 06078SE-A Start Date*: 2006-10-25
    Sponsor Name:Belfast City Hospital Trust
    Full Title: Investigation of the anti-inflammatory effects of simvastatin in a model of acute lung injury after inhalation of lipopolysaccharide by healthy volunteers
    Medical condition: Acute lung injury (ALI)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-004613-10 Sponsor Protocol Number: IRIVITC2008 Start Date*: 2008-09-12
    Sponsor Name:University College Hospital Galway
    Full Title: The role of the antioxidants ascorbic acid and n-acetylcysteine in the attenuation of ischaemia reperfusion injury in a human model
    Medical condition: Ischaemia reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063837 Reperfusion injury LLT
    9.1 10063837 Reperfusion injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005381-35 Sponsor Protocol Number: EP-DICLO/G-04-2012 Start Date*: 2013-06-20
    Sponsor Name:EPIFARMA SRL
    Full Title: Randomized, double-blind, placebo-controlled, parallel group, multi-centre clinical trial to evaluate safety and efficacy of Diclofenac 1% gel vs. placebo gel in patients with acute traumatic blunt...
    Medical condition: Patients with acute traumatic blunt soft tissue injury/contusion of the limbs.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004863 10041292 Soft tissue injury NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001824-23 Sponsor Protocol Number: CME-LEC1 Start Date*: 2017-11-29
    Sponsor Name:Fundación de Investigación Biomédica del Hospital Universitario Puerta de Hierro-Majadahonda (FIBM-HUPHM)
    Full Title: Intrathecal administration of autologous adult bone marrow mesenchymal stem cells expanded in the diffuse axonal injury.
    Medical condition: Traumatic cerebral injury, chronically established attributed to diffuse axonal injury.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002083-25 Sponsor Protocol Number: LIDO2011 Start Date*: 2011-12-05
    Sponsor Name:BG University Hospital Bergmannsheil GmbH
    Full Title: Is there a correlation between the pain relief and the A-delta- and C-fiber function after topical application of lidocaine (5%) in patients with peripheral neuropathic pain?
    Medical condition: Patients with proven diagnosis of painful peripheral neuropathic pain syndromes as diagnosed as: 1. Peripheral nerve lesion or 2. Postherpetic neuralgia.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10036376 Post herpetic neuralgia PT
    14.0 10022117 - Injury, poisoning and procedural complications 10034586 Peripheral nerve injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001688-66 Sponsor Protocol Number: SC.14/18-19 Start Date*: 2019-09-09
    Sponsor Name:University of Warwick [...]
    1. University of Warwick
    2. University Hospitals Birmingham NHS Foundation Trust
    Full Title: Sugar or Salt (SOS) trial: Hyperosmolar therapy in traumatic brain injury
    Medical condition: Increased intracranial pressure following traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2021-000346-18 Sponsor Protocol Number: BST-SCI-02 Start Date*: 2021-06-28
    Sponsor Name:Banc de Sang i Teixits
    Full Title: A phase I/II, randomized, double-blind, placebo-controlled, parallel, 2-arms clinical trial to assess the safety and efficacy of intrathecal administration of WJ-MSC in chronic traumatic cervical i...
    Medical condition: Cronic traumatic spinal cord injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10041554 Spinal cord injury cervical PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000140-58 Sponsor Protocol Number: NL7255100000 Start Date*: 2020-07-23
    Sponsor Name:Leiden University Medical Center
    Full Title: Complement Inhibition: Attacking the Overshooting Inflammation @fter Traumatic Brain Injury - A phase II trial on the safety and efficacy of C1 esterase inhibitor Cinryze for the acute management o...
    Medical condition: Severe traumatic Brain Injury (TBI) with GCS < 13
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-004102-42 Sponsor Protocol Number: EP-DICLO/2G-01-2015 Start Date*: 2017-06-06
    Sponsor Name:Epifarma S.r.l.
    Full Title: Randomized, multi-center, double-blind, three-armed trial, to evaluate the non-inferiority, efficacy and safety of diclofenac2% gel (Test) versus the originator diclofenac2% gel chosen as Referenc...
    Medical condition: Acute traumatic events (injury/contusion) classified from mild to moderate pain at rest to the joints, muscles, tendons and ligaments
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10022117 Injury, poisoning and procedural complications SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) LV (Completed) LT (Completed) HU (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006855-10 Sponsor Protocol Number: RXQ229 Start Date*: 2007-02-23
    Sponsor Name:Buckinghamshire Hospitals NHS Trust
    Full Title: A randomised trial of rectal stimulants for neurogenic bowel management after spinal cord injury
    Medical condition: Response of the neurogenic bowel after spinal cord injury to pharmacological rectal stimulants
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-002991-28 Sponsor Protocol Number: N/A Start Date*: 2016-10-24
    Sponsor Name:University of Oxford
    Full Title: GRASP: Getting it Right: Addressing Shoulder Pain. Clinical and cost effectiveness of progressive exercise compared to best practice advice, with or without corticosteroid injection, for the treat...
    Medical condition: Rotator Cuff Partial Tear (not full tear)
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10039226 Rotator cuff injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005375-16 Sponsor Protocol Number: A-99-52120-162 Start Date*: 2012-02-20
    Sponsor Name:Institut Produits Synthèse (IPSEN) AB
    Full Title: A PHASE III PROSPECTIVE, MULTI-CENTER, RANDOMISED, EVALUATOR-BLINDED STUDY TO COMPARE NEUROMUSCULAR JUNCTION (NMJ) TARGETED TECHNIQUE FOR DYSPORT INJECTIONS IN UPPER LIMB SPASTICITY POST STROKE OR ...
    Medical condition: Upper limb spasticity post stroke or traumatic brain injury.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004852 10048970 Arm spasticity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) FI (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-004994-30 Sponsor Protocol Number: NL68837.091.21 Start Date*: 2022-02-08
    Sponsor Name:Roessingh
    Full Title: Pulmonary function and sleep related disorders during cervical admission of intrathecal baclofen in spinal cord injury; a safety study
    Medical condition: Spasticity in patients with spinal cord injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-003771-18 Sponsor Protocol Number: GWSP08258 Start Date*: 2013-08-06
    Sponsor Name:GW Pharma Ltd.
    Full Title: The efficacy, safety and tolerability of Sativex as an adjunctive treatment to existing anti-spasticity medications in children aged 8 to 18 years with spasticity due to cerebral palsy or traumatic...
    Medical condition: Spasticity due to cerebral palsy (CP) or traumatic central nervous system injury.
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10028335 Muscle spasticity PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2015-003073-15 Sponsor Protocol Number: 0504 Start Date*: 2016-02-12
    Sponsor Name:Research Governance, University of Leicester
    Full Title: HYDration and bicarbonate to prevent acute Renal injury after endovascular Aneurysm repair: pilot-feasibility randomized controlled study (HYDRA pilot trial)
    Medical condition: Acute kidney injury post endovascular repair of the abdominal aortic aneurysm.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10000051 Abdominal aneurysm LLT
    20.0 100000004866 10000054 Abdominal aortic aneurysm LLT
    20.0 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    20.0 10038359 - Renal and urinary disorders 10068736 Acute oliguric renal failure LLT
    20.1 10038359 - Renal and urinary disorders 10001041 Acute renal failure LLT
    20.0 10038359 - Renal and urinary disorders 10001051 Acute renal failure, unspecified LLT
    20.0 10038359 - Renal and urinary disorders 10070787 Anuric renal failure LLT
    20.0 10038359 - Renal and urinary disorders 10068736 Acute oliguric renal failure LLT
    20.1 10038359 - Renal and urinary disorders 10001041 Acute renal failure LLT
    20.0 10038359 - Renal and urinary disorders 10001051 Acute renal failure, unspecified LLT
    20.0 10038359 - Renal and urinary disorders 10070787 Anuric renal failure LLT
    20.0 10042613 - Surgical and medical procedures 10061657 Arterial stent insertion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006034-18 Sponsor Protocol Number: 06004 Start Date*: 2007-05-21
    Sponsor Name:Medicure International Inc.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER STUDY TO EVALUATE THE CARDIOPROTECTIVE EFFECTS OF MC-1 IN PATIENTS UNDERGOING HIGH-RISK CORONARY ARTERY BYPASS GRAFT (CABG) SURGERY
    Medical condition: For treatment to reduce cardiovascular events associated with ischemic damage and/or ischemia-reperfusion injury in patients undergoing CABG surgery.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10051624 Myocardial reperfusion injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003088-87 Sponsor Protocol Number: WWU20_0016 Start Date*: 2021-11-22
    Sponsor Name:Westfälische Wilhelms-Universität Münster
    Full Title: Biomarker-guided implementation of angiotensin-II (AT-II) to reduce the occurrence of kidney damage after cardiac surgery
    Medical condition: Cardiac surgical patients at high risk for AKI
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    20.1 10038359 - Renal and urinary disorders 10080266 Stage 1 acute kidney injury LLT
    20.1 10038359 - Renal and urinary disorders 10080269 Stage 2 acute kidney injury LLT
    20.1 10038359 - Renal and urinary disorders 10080271 Stage 3 acute kidney injury LLT
    20.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: View results
    EudraCT Number: 2010-020452-64 Sponsor Protocol Number: version2.0 Start Date*: 2010-10-05
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A prospective randomisd open label study to determine the effects of intravenous iron administration on markers of acute kidney injury in chronic kidney disease (CKD)
    Medical condition: patients with known chonic kidney disease with functional or absolute Iron deficiency Anaemia, and are greater than 18 years will be given repleacement iron therapy accoring to current local protoc...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10005329 - Blood and lymphatic system disorders 10022973 Iron deficiency anaemias LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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