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Clinical trials for Dose-response curve

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    63 result(s) found for: Dose-response curve. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2007-007094-23 Sponsor Protocol Number: Nitrous oxide protocol V5 Start Date*: 2008-10-09
    Sponsor Name:University of Nottingham
    Full Title: Nitrous oxide and cerebral vasodilatation: a dose-response study in healthy volunteers
    Medical condition: The study will be conducted in healthy volunteers. I will evaluate the effects of inhaled concentrations of nitrous oxide, ranging from 0% to 50%, on cerebral blood flow and cerebral vascular tone ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000888-26 Sponsor Protocol Number: DEV 1477-2 DIC 05 Start Date*: 2005-11-07
    Sponsor Name:ratiopharm GmbH
    Full Title: Randomised, double-blind, multi-centre, placebo-controlled clinical dose finding study in four parallel groups comparing Diclofenac Gel 1 %, Diclofenac Gel 3 %, Diclofenac Gel 5 % and placebo Gel i...
    Medical condition: Male or female ambulant patients (age range 18-60 years) suffering from fresh impact injuries (traumatic blunt soft tissue injury/contusion). Time elapse between traumatic event and inclusion must ...
    Disease: Version SOC Term Classification Code Term Level
    10022117 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003385-34 Sponsor Protocol Number: CRU.LUMC.001 Start Date*: 2006-11-23
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: The effect of tiotropium-bromide on deep inspiration-induced bronchodilation and airway responsiveness in asthma.
    Medical condition: 24 patients with mild persistent asthma will participate in the study. All patients will be allergic to one or more airborne allergens, hyperresponsive to histamine (PC20 < 8 mg/ml) and have a norm...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000540-98 Sponsor Protocol Number: 2005/495-31 Start Date*: 2006-04-10
    Sponsor Name:Karolinska University Hospital
    Full Title: Substudie Bröstmärta provocerad med iv bolus adenosin injektion i huvudstudie: Jämförelse mellan aktiv och passiv fysisk träning för behandling av persisterande angina pectoris - en randomiserad st...
    Medical condition: Refractory angina pectoris. Testing of sensitivity of chest pain provoked by iv bolus of adenosin before and after a training period with EECP (Enhanced External Counterpulsation) or physical exerc...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001430-35 Sponsor Protocol Number: 35RC19_8860_FLUDROSEPSIS Start Date*: 2021-04-21
    Sponsor Name:CHU Rennes
    Full Title: Evaluation of the hemodynamic effects of fludrocortisone on the pressive response to norepinephrine in patients in septic shock
    Medical condition: septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002868-14 Sponsor Protocol Number: CLIK066B2201 Start Date*: 2017-04-18
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, double-blind, dose-finding study to evaluate the change in weight after 24 weeks treatment with 8 doses of LIK066 compared to placebo in obese or overweight adults, followed by 24 wee...
    Medical condition: change in weight in obese or overweight adults
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    20.0 10027433 - Metabolism and nutrition disorders 10033307 Overweight PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) CZ (Completed) AT (Completed) HU (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-000882-41 Sponsor Protocol Number: NN9535-4984 Start Date*: 2022-07-27
    Sponsor Name:Novo Nordisk A/S
    Full Title: Investigation of once-weekly semaglutide s.c. dose-response in patients with type 2 diabetes and overweight – a participant- and investigator-blinded and sponsor open-label study
    Medical condition: Diabetes Mellitus, Type 2 Overweight
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    24.1 10027433 - Metabolism and nutrition disorders 10033307 Overweight PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) GR (Trial now transitioned) PL (Completed)
    Trial results: View results
    EudraCT Number: 2018-004624-11 Sponsor Protocol Number: Jonto01 Start Date*: 2019-03-13
    Sponsor Name:Region Östergötland
    Full Title: A non-randomized experimental study to optically study pharmacodynamic responses in the delivery of vasoactive substances to the skin through iontophoresis in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2024-000202-16 Sponsor Protocol Number: MLB-01-003 Start Date*: 2024-05-31
    Sponsor Name:ML Bio Solutions
    Full Title: AN OPEN LABEL PHASE 2 STUDY OF BBP 418 IN PATIENTS WITH LIMB GIRDLE MUSCULAR DYSTROPHY TYPE 2I (MLB 01 003)
    Medical condition: Limb Girdle Muscular Dystrophy 2I/R9
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2021-003304-41 Sponsor Protocol Number: 1397-0012 Start Date*: 2022-06-09
    Sponsor Name:Boehringer Ingelheim SComm
    Full Title: A randomised, double-blind, placebo-controlled, parallel group, dose-finding study evaluating efficacy, safety and tolerability of BI 1291583 qd over at least 24 weeks in patients with bronchiectas...
    Medical condition: bronchiectasis
    Disease: Version SOC Term Classification Code Term Level
    21.0 10038738 - Respiratory, thoracic and mediastinal disorders 10006445 Bronchiectasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Completed) ES (Completed) HU (Completed) FR (Completed) IT (Completed) LV (Completed) CZ (Completed) DE (Completed) GR (Completed) DK (Completed) PL (Completed) PT (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003791-40 Sponsor Protocol Number: PSX100201 Start Date*: 2012-11-26
    Sponsor Name:Prosonix Limited
    Full Title: An Investigation of the Efficacy, Tolerability and Safety of a Range of Doses of Orally Inhaled Glycopyrronium Bromide (PSX1002-GB pMDI) in Male and Female Patients with Moderate or Severe Chronic ...
    Medical condition: Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002479-37 Sponsor Protocol Number: 1404-0036 Start Date*: 2021-03-15
    Sponsor Name:Boehringer Ingelheim AB
    Full Title: A Phase II, randomized, double blind, parallel group,46 weeks dose-finding study of BI 456906 administered once weekly subcutaneously compared with placebo in patients with obesity or overweight
    Medical condition: obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) IE (Prematurely Ended) NL (Completed) BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018987-17 Sponsor Protocol Number: EP-101-02 Start Date*: 2010-06-22
    Sponsor Name:Elevation Pharmaceuticals, Inc.
    Full Title: Randomized, Placebo-Controlled, Double-Blind, Dose Ranging, Single Dose, 6-Way Crossover Study to Assess the Safety, Efficacy and Pharmacokinetics of EP-101 Using eFlow Nebulizer in Patients with COPD
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-003330-91 Sponsor Protocol Number: BUSAL-II-17-1 Start Date*: 2017-11-29
    Sponsor Name:Laboratoires SMB S.A.
    Full Title: A pharmacokinetic and pharmacodynamic, randomised, single dose, cross-over, partially blinded study to compare the systemic exposure and the efficacy of a fixed-dose combination of Budesonide-Salme...
    Medical condition: Regular Treatment of Asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000015470 10003560 Asthma NOS LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2020-000469-18 Sponsor Protocol Number: IP2018CS01 Start Date*: 2020-06-26
    Sponsor Name:Initiator Pharma
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients
    Medical condition: Male patients with a diagnosis of mild to moderate depression and ED as determined from the Hamilton depression scale score of 7 to 23 and International Index of Erectile Function (IIEF-5) score of...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-002663-11 Sponsor Protocol Number: PSD506-OAB-002 Start Date*: 2006-10-17
    Sponsor Name:Plethora Solutions Limited
    Full Title: An open-label, escalating dose, proof of concept study to determine the effects of single oral doses of PSD506 on unstable urinary bladder contractions induced by volume provocation in subjects wit...
    Medical condition: Unstable urinary bladder contractions induced by volume provocation in subjects with detrusor hyper-reflexia secondary to spinal injuries above T12.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012547 Detrusor hyperreflexia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012815-16 Sponsor Protocol Number: ROSANNA Start Date*: 2010-03-18
    Sponsor Name:Technische Universität München
    Full Title: Dosis-Wirkungsstudie von Rocuronium unter Propofol-Anästhesie (Rocuronium Dose Finding Study after single shot or steady state propofol anesthesia)
    Medical condition: Rocuronium dose finding study; evaluation of effective doses (ED 50 and ED 95) of rocuronium after single shot or steady state propofol anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029315 Neuromuscular blockade LLT
    9.1 10029315 Neuromuscular blockade PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-008719-25 Sponsor Protocol Number: CBAF312A2201 Start Date*: Information not available in EudraCT
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A phase II, double-blind, randomized, multi-center, adaptive dose-ranging, placebo-controlled, parallel-group study evaluating safety, tolerability and efficacy on MRI lesion parameters and determi...
    Medical condition: Relapsing-remitting multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063399 Relapsing-remitting multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) ES (Completed) IT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2013-001799-39 Sponsor Protocol Number: CBAF312X2206 Start Date*: 2013-09-26
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A double blind, randomized, placebo-controlled study to evaluate, safety, tolerability, efficacy and preliminary dose-response of BAF312 in patients with active dermatomyositis.
    Medical condition: Active dermatomyositis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10040785 - Skin and subcutaneous tissue disorders 10012503 Dermatomyositis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Prematurely Ended) PL (Prematurely Ended) BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-006121-26 Sponsor Protocol Number: BU-001-IM Start Date*: Information not available in EudraCT
    Sponsor Name:Nycomed Danmark ApS
    Full Title: An international, randomised, double blinded, multi-centre, active- and placebo-controlled dose response trial to evaluate the efficacy and safety of SABER-Bupivacaine for postoperative pain contro...
    Medical condition: Postoperative pain in patients undergoing primary, elective, open, abdominal hysterectomy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) GB (Prematurely Ended) HU (Completed) FR (Completed) SE (Completed) LV (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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