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Clinical trials for Dry Eye Syndromes AND Dry Eye Syndrome

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    13 result(s) found for: Dry Eye Syndromes AND Dry Eye Syndrome. Displaying page 1 of 1.
    EudraCT Number: 2015-002507-28 Sponsor Protocol Number: OPHT-280515 Start Date*: 2015-07-20
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of benzalkonium chloride containing eye drops on the conjunctival bacterial flora of dry eye patients.
    Medical condition: conjunctival bacterial flora in patients with dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005405-36 Sponsor Protocol Number: LT1580-301 Start Date*: 2016-05-10
    Sponsor Name:Laboratoires Théa
    Full Title: EFFICACY AND SAFETY ASSESSMENT OF T1580 VERSUS VEHICLE IN DRY EYE DISEASE TREATMENT
    Medical condition: Dry Eye
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000014904 10013778 Dry eyes LLT
    20.0 100000014904 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed) HU (Prematurely Ended) LV (Prematurely Ended) AT (Prematurely Ended) GB (Prematurely Ended) LT (Prematurely Ended) GR (Prematurely Ended) CZ (Prematurely Ended) BG (Prematurely Ended) PL (Prematurely Ended) HR (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-002183-63 Sponsor Protocol Number: IOBA-CERLab-003-2013 Start Date*: 2013-11-12
    Sponsor Name:IOBA
    Full Title: Unicenter, double masked, crossover clinical trial to assess the efficacy of FML (0.1% Fluorometolone) in dry eye patients
    Medical condition: Dry eye syndrome (DES)
    Disease: Version SOC Term Classification Code Term Level
    16.0 10015919 - Eye disorders 10013777 Dry eye syndrome LLT
    16.0 10015919 - Eye disorders 10013774 Dry eye PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000160-97 Sponsor Protocol Number: NVG10E117 Start Date*: 2011-04-08
    Sponsor Name:NOVAGALI Pharma S.A.
    Full Title: A MULTICENTER, RANDOMIZED, DOUBLE-MASKED, 2 PARALLEL ARM, VEHICLE CONTROLLED, 6-MONTH PHASE III TRIAL WITH A 6 MONTH OPEN LABEL TREATMENT SAFETY FOLLOW-UP PERIOD TO EVALUATE THE EFFICACY AND SAFETY...
    Medical condition: Severe Dry Eye Disease
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10013774 Dry eye PT
    13.1 10015919 - Eye disorders 10013777 Dry eye syndrome LLT
    13.1 10015919 - Eye disorders 10023350 Keratoconjunctivitis sicca PT
    13.1 10015919 - Eye disorders 10013778 Dry eyes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) BE (Completed) DE (Completed) IT (Ongoing) AT (Completed) GB (Completed) CZ (Completed) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-002066-12 Sponsor Protocol Number: NVG12D122 Start Date*: 2012-12-13
    Sponsor Name:NOVAGALI Pharma S.A.S
    Full Title: A Multicenter, Open Label, Interventional, Prospective, Non Randomized, One Cohort Extension Study To Assess the Sustainability of the Effect of NOVA22007 Following Treatment Discontinuation in Imp...
    Medical condition: Severe Dry Eye Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10023350 Keratoconjunctivitis sicca LLT
    14.1 10015919 - Eye disorders 10013778 Dry eyes LLT
    14.1 10015919 - Eye disorders 10013777 Dry eye syndrome LLT
    14.1 10015919 - Eye disorders 10013774 Dry eye PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) AT (Completed) DE (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000937-54 Sponsor Protocol Number: MC2-03-C1 Start Date*: 2015-08-03
    Sponsor Name:DRUG DELIVERY SOLUTIONS ApS (PART OF MC2 BIOTEK GROUP)
    Full Title: A phase II, multicenter, randomized, double-masked, 4 parallel arms, controlled 6-month trial designed to evaluate the safety and efficacy of PAD ciclosporin (CsA 0.06% and 0.03%) ophthalmic disper...
    Medical condition: ocular dryness (Dry Eye Disease - DED)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000014904 10013778 Dry eyes LLT
    20.0 100000014904 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DK (Completed) NO (Completed) AT (Completed) ES (Completed) PT (Completed) FR (Completed) SK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2015-002508-94 Sponsor Protocol Number: OPHT-030815 Start Date*: 2015-10-06
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of topical azithromycin on tear film thickness in patients with meibomian gland dysfunction – comparison to oral treatment with doxycycline
    Medical condition: Meibomian gland dysfunction Dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10065062 Meibomian gland dysfunction PT
    20.0 100000014904 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-004271-12 Sponsor Protocol Number: NGF0213 Start Date*: 2014-01-17
    Sponsor Name:Dompé s.p.a
    Full Title: An open-label study evaluating safety and efficacy of recombinant human nerve growth factor (rhNGF) eye drops at different doses in patients with Dry Eye
    Medical condition: Dry Eye syndrome is caused by either decreased tear production or increased tear film evaporation. Dry eye is a chronic inflammatory condition of the ocular surface with severe symptoms and visual ...
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003285-27 Sponsor Protocol Number: T1565-PIV-0117 Start Date*: 2017-09-26
    Sponsor Name:Laboratoires Thea
    Full Title: Clinical efficacy of topical hydrocortisone 0.335% (Softacort®) in patients with chronic dry eye disease and associated ocular surface inflammation
    Medical condition: Dry Eye Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001720-33 Sponsor Protocol Number: CSA_2020 Start Date*: 2020-09-08
    Sponsor Name:UNIVERSITÀ CAMPUS BIO-MEDICO DI ROMA
    Full Title: Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age
    Medical condition: High-risk patients, i.e. elder patients, who show dry eye syndrome after insult.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000747-27 Sponsor Protocol Number: 049/SI Start Date*: 2020-09-09
    Sponsor Name:SOCIETÀ INDUSTRIA FARMACEUTICA ITALIANA (SIFI) SPA
    Full Title: A Multicenter, Randomized, Double-Masked, Placebo-Controlled Phase II Study to evaluate the Safety and Efficacy of Pro-ocular™ 0.5% and 1% in Patients with Dry Eye Syndrome
    Medical condition: Dry Eye is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film and accompanied by ocular symptoms, in which tear film instability, hyperosmolarity...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001022-34 Sponsor Protocol Number: AVX012-CT-001 Start Date*: 2016-10-06
    Sponsor Name:AVIZOREX PHARMA, S.L.
    Full Title: A phase I/II, double-blind, placebo-controlled study assessing the safety and efficacy of AVX-012 ophthalmic solution in subjects with mild-to-moderate dry eye syndrome
    Medical condition: Dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002172-27 Sponsor Protocol Number: NGF0116 Start Date*: 2016-11-09
    Sponsor Name:DOMPé FARMACEUTICI S.P.A.
    Full Title: A 8 weeks, Phase II, single-centre, randomized, double-masked, vehicle-controlled, parallel group study with 4 weeks of follow-up to evaluate preliminary efficacy and safety of recombinant human Ne...
    Medical condition: patients after cataract and refractive surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10015919 Eye disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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