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Clinical trials for Emergency

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    874 result(s) found for: Emergency. Displaying page 1 of 44.
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    EudraCT Number: 2015-002485-24 Sponsor Protocol Number: CHUBX2014/09 Start Date*: 2015-08-11
    Sponsor Name:CHU de Bordeaux
    Full Title: Effectiveness of oral prednisolone versus partial endodontic treatment on pain reduction in emergency care of acute irreversible pulpitis of mandibular molars: study protocol for a non inferiority ...
    Medical condition: Pulpitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003387-55 Sponsor Protocol Number: 2914-004 Start Date*: 2007-11-15
    Sponsor Name:Laboratoire HRA Pharma
    Full Title: " A Prospective, Randomized, Single Blind, Multicenter Study to Compare the Efficacy, Safety and Tolerability of CDB-2914 with Levonorgestrel as Emergency Contraception Within 120 Hours Unprotected...
    Medical condition: Emergency contraception
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004300-19 Sponsor Protocol Number: 18-PP-04 Start Date*: 2019-03-07
    Sponsor Name:CHU DE NICE
    Full Title: Target-controled infusion with propofol in the Emergency Department : a prospective study on 50 adult patients
    Medical condition: Joint dislocation ; Limb displaced fracture
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10075886 Limb fractures and dislocations HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002686-15 Sponsor Protocol Number: CHUBX2021/25 Start Date*: 2022-10-18
    Sponsor Name:CHU de Bordeaux
    Full Title: Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on postintubation Morbidity: A cluster randomized controlled trial
    Medical condition: respiratory distress
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001297-41 Sponsor Protocol Number: OY072017 Start Date*: 2018-02-13
    Sponsor Name:Oulu university hospital
    Full Title: Intranasal dexmedetomidine sedation and analgesia during minor procedures in the pediatric emergency room : Randomized double-blinded clinical trial
    Medical condition: Patients of the pediatric emergency room at Oulu University Hospital with any medical condition requiring a minor painful procedure such as i.v. cannulation or lumbar puncture are asked to join our...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-005170-11 Sponsor Protocol Number: UCLDexAlf1 Start Date*: 2015-01-26
    Sponsor Name:Cliniques universitaires Saint Luc
    Full Title: Can we get conscious sedation in optimal safety conditions in an emergency department, by combining dexmedetomidine with alfentanil?
    Medical condition: Adult over 18 years, of both sexes, for which a procedural sedation is needed in emergency room.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-006427-18 Sponsor Protocol Number: 2021.143 Start Date*: 2022-08-26
    Sponsor Name:Anna Coquard Rafales
    Full Title: M-POC-O2: high flow nasal cannula oxygen versus conventional oxygen therapy in exacerbated chronic obstructive pulmonary disease (COPD) patients without respiratory acidosis. Pilot Study.
    Medical condition: Patients older than 35 years old with COPD diagnosis (chronic obstructive pulmonary disease) by spirometry, presenting acute exacerbation without respiratory acidosis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005442-37 Sponsor Protocol Number: CT200601 Start Date*: 2007-01-08
    Sponsor Name:University Medical Center St Radboud, department of neurology
    Full Title: PITUITARY DAMAGE AFTER TRAUMATIC BRAIN INJURY; Occurrence of growth hormone deficiency at long term follow-up and the beneficial effects of growth hormone substitution on cardiovascular performance...
    Medical condition: isolated growth hormone deficiency after traumatic brain injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002308-15 Sponsor Protocol Number: P160913 Start Date*: 2018-11-09
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: COrticosteroids in acUte uRticAria in emerGency dEpartment
    Medical condition: Adults patients with isolated acute urticaria presenting to the emergency department
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10001106 Acute urticaria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-003220-36 Sponsor Protocol Number: 45112 Start Date*: 2014-05-21
    Sponsor Name:Albert Schweitzer hospital
    Full Title: Remifentanil use for procedural sedation and analgesia in the emergency department
    Medical condition: The research will be conducted in patients that need short painfull treatment in the emergency department and with an indication for PSA. These treatments include: repositioning of fractures, repos...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002177-37 Sponsor Protocol Number: 1321.7 Start Date*: 2016-06-01
    Sponsor Name:Boehringer Ingelheim AB
    Full Title: Single dose, open label, uncontrolled, safety trial of intravenous administration of idarucizumab to paediatric patients enrolled from ongoing phase IIb/III clinical trials with dabigatran etexilat...
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004866 10066899 Venous thromboembolism LLT
    18.1 100000004865 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed) LT (Completed) CZ (Completed) IT (Completed) DE (Completed) Outside EU/EEA GR (Completed) HU (Completed) BE (Completed) ES (Prematurely Ended) BG (Completed) AT (Completed) FI (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-001601-82 Sponsor Protocol Number: MR311-3506(AMBU-001) Start Date*: 2019-07-08
    Sponsor Name:Mundipharma Pharmaceuticals B.V.
    Full Title: Open randomized clinical trial to compare pain relief between low-dose methoxyflurane and standard of care for the treatment of patients with trauma pain in emergency medical services in the Nether...
    Medical condition: Patients with moderate trauma pain due to extremity injuries for whom the emergency medical services have been called.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-000503-16 Sponsor Protocol Number: P170903J Start Date*: 2021-02-12
    Sponsor Name:Assistance Publique- Hôpiaux de Paris
    Full Title: Randomized, double-blind, single-centre, randomized study evaluating the efficacy of CLORazepate dipotassium in the treatment of migraine crisis in the emergency department.
    Medical condition: Adults of full age, excluding pregnant or breastfeeding women, admitted to the CUC for headaches
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-000634-35 Sponsor Protocol Number: ALT-OXI-2018 Start Date*: 2018-10-31
    Sponsor Name:Althaia Xarxa Assistencial Universitària de Manresa. Fundació Privada.
    Full Title: HIGH-FLOW NASAL CANNULA THERAPY AS AN ADJUVANT IN THE TREATMENT OF SEVERE SEPSIS. A Multicenter parallel-group randomized clinical trial.
    Medical condition: Patients > 18 yr. with diagnostic criteria for severe sepsis, within 6 hours of admission in the Emergency Room, defined as hypotension after hemodynamic resuscitation, initial lactate > 4, or pers...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002137-39 Sponsor Protocol Number: V1 25/07/04 Start Date*: 2004-09-17
    Sponsor Name:
    Full Title: A randomised controlled trial of the combined use of paracetamol and ibuprofen to treat febrile children
    Medical condition: Fevers in childhood not asscoaited with severe disease in the immunocompenetent or fever in the immunocompromised host.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-002897-23 Sponsor Protocol Number: 107564 Start Date*: 2006-09-05
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: An observational study to investigate the incidence of influenza and influenza-related complications, in adults between 50-64 years and elderly adults 65 years and over vaccinated with GSK Biologic...
    Medical condition: Immunization against influenza in male and female subjects aged 50 years and over
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001665-16 Sponsor Protocol Number: 1312 Start Date*: 2013-08-01
    Sponsor Name:University Hospital Grenoble
    Full Title: Intranasal Sufentanyl analgesia Versus Morphine IV in Emergency room.
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-000194-31 Sponsor Protocol Number: PenCTU/2010/CTIMP-004 Start Date*: 2011-05-20
    Sponsor Name:Plymouth Hospitals NHS Trust
    Full Title: An open randomised trial of patient controlled analgesia (PCA) versus routine care in the Emergency Department
    Medical condition: Patients presenting to the Emergency Department in severe pain from either musculoskeletal injury or non-traumatic abdominal pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-005116-64 Sponsor Protocol Number: 16092021 Start Date*: 2021-12-13
    Sponsor Name:Aarhus University Hospital, Department of Anesthesiology
    Full Title: Low-dose ketamine as an adjunct to morphine for acute pain in the ED: a randomized, double-blinded, superiority trial
    Medical condition: Acute pain in the Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-003773-17 Sponsor Protocol Number: dex_version1 Start Date*: 2017-06-12
    Sponsor Name:Karolinska University Hospital
    Full Title: A prospective randomized open label study Intranasal dexmedetomidine versus inhaled nitrous oxide for children age 3 – 15 years for procedural sedation and analgesia in pediatric emergency departme...
    Medical condition: sedation for emergency procedures
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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