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Clinical trials for Emergency care

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    447 result(s) found for: Emergency care. Displaying page 1 of 23.
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    EudraCT Number: 2015-002485-24 Sponsor Protocol Number: CHUBX2014/09 Start Date*: 2015-08-11
    Sponsor Name:CHU de Bordeaux
    Full Title: Effectiveness of oral prednisolone versus partial endodontic treatment on pain reduction in emergency care of acute irreversible pulpitis of mandibular molars: study protocol for a non inferiority ...
    Medical condition: Pulpitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002686-15 Sponsor Protocol Number: CHUBX2021/25 Start Date*: 2022-10-18
    Sponsor Name:CHU de Bordeaux
    Full Title: Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on postintubation Morbidity: A cluster randomized controlled trial
    Medical condition: respiratory distress
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-003220-36 Sponsor Protocol Number: 45112 Start Date*: 2014-05-21
    Sponsor Name:Albert Schweitzer hospital
    Full Title: Remifentanil use for procedural sedation and analgesia in the emergency department
    Medical condition: The research will be conducted in patients that need short painfull treatment in the emergency department and with an indication for PSA. These treatments include: repositioning of fractures, repos...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-001601-82 Sponsor Protocol Number: MR311-3506(AMBU-001) Start Date*: 2019-07-08
    Sponsor Name:Mundipharma Pharmaceuticals B.V.
    Full Title: Open randomized clinical trial to compare pain relief between low-dose methoxyflurane and standard of care for the treatment of patients with trauma pain in emergency medical services in the Nether...
    Medical condition: Patients with moderate trauma pain due to extremity injuries for whom the emergency medical services have been called.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-000194-31 Sponsor Protocol Number: PenCTU/2010/CTIMP-004 Start Date*: 2011-05-20
    Sponsor Name:Plymouth Hospitals NHS Trust
    Full Title: An open randomised trial of patient controlled analgesia (PCA) versus routine care in the Emergency Department
    Medical condition: Patients presenting to the Emergency Department in severe pain from either musculoskeletal injury or non-traumatic abdominal pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001665-16 Sponsor Protocol Number: 1312 Start Date*: 2013-08-01
    Sponsor Name:University Hospital Grenoble
    Full Title: Intranasal Sufentanyl analgesia Versus Morphine IV in Emergency room.
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2019-002498-80 Sponsor Protocol Number: 06062019 Start Date*: 2019-09-24
    Sponsor Name:Mikkel Brabrand
    Full Title: Will titrated oxygen flow to a peripheral oxygen saturation of 88-92% compared with oxygen flow to a saturation >94% reduce mortality in Chronic Obstructive Pulmonary Disease patients with acute ex...
    Medical condition: Acute COPD Exacerbation
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001081-80 Sponsor Protocol Number: NL22172 Start Date*: 2008-06-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population with Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort...
    Medical condition: To determine whether a 7-day duration of antibiotic treatment is non inferior to 14-day standard duration of treatment in adults presenting at primary care or emergency department with febrile uri...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004469-28 Sponsor Protocol Number: MR311-4501 Start Date*: 2018-03-01
    Sponsor Name:MUNDIPHARMA
    Full Title: Multicentre, randomised, double-blind study assessing the efficacy and safety of Penthrox® combined with a standard analgesia (SoC) in comparison to a placebo combined with a standard analgesia (So...
    Medical condition: Emergency relief of moderate to severe pain associated with trauma in conscious adult patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10044461 Trauma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001401-25 Sponsor Protocol Number: QHD00012 Start Date*: 2019-09-27
    Sponsor Name:Sanofi Pasteur Inc.
    Full Title: Relative Effectiveness of a High-Dose Quadrivalent Influenza Vaccine versus a Standard-Dose Quadrivalent Influenza Vaccine in Subjects 65 Years of Age and Older
    Medical condition: Prevention of influenza infection in adults from 65 years of age and older
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000333-36 Sponsor Protocol Number: 17012006 Start Date*: 2006-04-26
    Sponsor Name:Hull & East Yorkhire NHS Hospitals Trust
    Full Title: A randomised comparison of 0.5% levobupivacaine with a lidocaine/epinephrine/ fentanyl mixture for epidural top up for emergency caesarean section after “low dose” epidural for labour
    Medical condition: pregnant women, in labour requiring emergency caesarean section under epidural anaesthesia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003145-42 Sponsor Protocol Number: DEXAURP Start Date*: 2014-02-26
    Sponsor Name:FRANCISCO JAVIER BENITO FERNANDEZ
    Full Title: PILOT RANDOMISED CONTROLLED TRIAL USIDNG DEXAMETHASONE VESUS PREDNISOLONA/PREDNISONA IN CHILDREN WITH ACUTE ASTHMA IN PEDIATRIC EMERGENCY WARD
    Medical condition: ASTHMA
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10049585 Infantile asthma PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001867-22 Sponsor Protocol Number: PRETIC Start Date*: 2018-09-27
    Sponsor Name:Banc de Sang i teixits
    Full Title: TRANSFUSION OF RED BLOOD CELLS, TRANEXAMIC ACID AND FIBRINOGEN CONCENTRATE FOR SEVERE TRAUMA HEMORRHAGE AT PRE-HOSPITAL PHASE OF CARE. A PILOT TRIAL.
    Medical condition: TREATMENT OF SEVERE TRAUMA HEMORRHAGE AT PRE-HOSPITAL PHASE OF CARE.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10019524 Hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001187-78 Sponsor Protocol Number: 112897 Start Date*: 2008-01-02
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The 3Mg Trial: A randomised controlled trial of intravenous or nebulised magnesium sulphate versus standard therapy for acute severe asthma
    Medical condition: Acute severe asthma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003566 Asthmatic attack LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-009596-35 Sponsor Protocol Number: Start Date*: 2009-03-17
    Sponsor Name:Queen Mary's, University of London
    Full Title: Optimisation of Peri-operative Cardiovascular Management to Improve Surgical Outcome (Optimise Trial)
    Medical condition: Post-operative complications in patients who undergo major surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001889-10 Sponsor Protocol Number: STOIC Start Date*: 2020-06-02
    Sponsor Name:University of Oxford, Clinical Trials and Research Governance
    Full Title: Use of inhaled corticosteroids as treatment of early COVID-19 infection to prevent clinical deterioration and hospitalisation
    Medical condition: COVID 19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2021-000890-10 Sponsor Protocol Number: MP0420-CP302 Start Date*: 2021-05-03
    Sponsor Name:Molecular Partners AG
    Full Title: A randomized, double-blind, placebo-controlled, multicenter study of ensovibep (MP0420) in ambulatory adult patients with symptomatic COVID-19
    Medical condition: Symptomatic COVID-19 in ambulatory patients
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005395-40 Sponsor Protocol Number: NSAP-01 Start Date*: 2007-05-03
    Sponsor Name:Barts and The London NHS Trust
    Full Title: Is Buscopan, paracetamol or a combination of both the most effective analgesia for the treatment of non-specific abdominal pain?
    Medical condition: Adult subjects attending the emergency department complaining of acute abdominal pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10000081 Abdominal pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022001-18 Sponsor Protocol Number: RESP_301_2010 Start Date*: 2011-06-30
    Sponsor Name:University College Dublin Clinical Research Centre
    Full Title: A Randomised Trial of Single Dose Oral Dexamethasone versus Multi-Dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in children who attend the Emergency Department
    Medical condition: Exacerbation of asthma in children presenting to the Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003566 Asthmatic attack LLT
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10015575 Exacerbation of asthma LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000224-35 Sponsor Protocol Number: RECEM00001 Start Date*: 2021-07-28
    Sponsor Name:Marie Kristine Jessen
    Full Title: Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients - a Multicenter, Randomized Clinical Feasibility Trial
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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