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Clinical trials for Eye drops

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    422 result(s) found for: Eye drops. Displaying page 1 of 22.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2013-000923-15 Sponsor Protocol Number: THILO08 Start Date*: 2013-05-24
    Sponsor Name:FARMEX SA
    Full Title: A multicenter, double-blind, randomized, parallel arm comparative study for the assessment of the safety and efficacy of azidamfenicol eye drops (Thilocof®/FARMEX) versus tobramycine eye drops (Τob...
    Medical condition: Infections of the outer eye layers (mainly bacterial conjuctivitis )
    Disease: Version SOC Term Classification Code Term Level
    16.0 10021881 - Infections and infestations 10010742 Conjunctivitis infective PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001642-18 Sponsor Protocol Number: WP3 Start Date*: 2019-12-05
    Sponsor Name:Department of Ophthalmology, Rigshospitalet-Glostrup
    Full Title: Effect on the ocular surface when treating glaucoma with eye drops: an investigation of the conjunctival goblet cells
    Medical condition: Open angular glaucoma and ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-005694-31 Sponsor Protocol Number: 2012/ADE002 Start Date*: 2013-07-05
    Sponsor Name:Adenovir Pharma AB
    Full Title: Evaluation of the Therapeutic Efficacy of APD-209 Eye Drops in Treatment of Acute Phase Adenoviral-Induced Epidemic Keratoconjunctivitis (EKC). A Randomised, Double-Masked, Placebo-Controlled, Mult...
    Medical condition: Acute phase Adenoviral-induced Epidemic Keratoconjunctivitis, EKC
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10014975 Epidemic keratoconjunctivitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2020-000429-17 Sponsor Protocol Number: 00 Start Date*: 2021-05-20
    Sponsor Name:University of Oslo, Faculty of Medicine, Institute of Health and Society
    Full Title: BASIC - Better treatment for acute sinusitis in primary care: a randomized controlled trial testing topical treatment with chloramphenicol eye drops
    Medical condition: Acute rhinosinusitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004201-29 Sponsor Protocol Number: CM-05-08/HU Start Date*: 2006-06-01
    Sponsor Name:Alcon Hungarian ltd
    Full Title: THE EFFICACY AND SAFETY OF TIMOLOL MALEATE 0.5% COMPARED TO BRINZOLAMIDE 1% EACH GIVEN TWICE DAILY WHEN ADDED TO TRAVOPROST 0.004% GIVEN EACH EVENING IN PRIMARY OPEN-ANGLE GLAUCOMA OR OCULAR HYPERT...
    Medical condition: Increased intraocular pressure and glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-004841-34 Sponsor Protocol Number: 101219 Start Date*: 2020-08-24
    Sponsor Name:Mika Harju
    Full Title: Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-003664-41 Sponsor Protocol Number: PMS/LEVO-001-06-2012 Start Date*: 2013-07-04
    Sponsor Name:Balkanpharma-Razgrad AD
    Full Title: Open-labeled, randomized, comparative clinical study of efficacy and safety of Levofloxan 0,5% eye drops in patients with Acute Bacterial Conjunctivitis.
    Medical condition: Acute Bacterial Conjunctivitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2015-002507-28 Sponsor Protocol Number: OPHT-280515 Start Date*: 2015-07-20
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of benzalkonium chloride containing eye drops on the conjunctival bacterial flora of dry eye patients.
    Medical condition: conjunctival bacterial flora in patients with dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004853 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002578-37 Sponsor Protocol Number: OPHT-240518 Start Date*: 2019-04-25
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: The effect of antibiotic eye drops on the nasal microbiome in healthy subjects
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-003296-30 Sponsor Protocol Number: 00172 Start Date*: 2015-11-11
    Sponsor Name:Raimo Tuuminen
    Full Title: Efficacy of steroid and nonsteroidal anti-inflammatory eye drops in management of post-operative inflammation and prevention of pseudophakic cystic macular edema after uncomplicated cataract surgery
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002588-17 Sponsor Protocol Number: SAM-IIT01 Start Date*: 2019-10-21
    Sponsor Name:Universitätsklinikum Tübingen
    Full Title: Safety and effects on visual function of 0.01% Atropin eye drops for myopia inhibition in children and adolescents
    Medical condition: Myopia
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003326-13 Sponsor Protocol Number: BTI-011-EC/15/QUER Start Date*: 2016-01-05
    Sponsor Name:BTI Biotechnology Institute I mas D
    Full Title: Randomized, parallel groups, multicenter and blind to evaluators clinical trial, to evaluate the efficacy and safety of PRGF-Endoret eye drops, in patients with stage 2 and 3 neurotrophic keratitis.
    Medical condition: Neurotrophic Keratitis (NK)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024513-31 Sponsor Protocol Number: C-10-041 Start Date*: 2011-06-15
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Efficacy and Safety of Brinzolamide 10 mg/ml / Brimonidine 2 mg/ml Eye Drops, Suspension Compared to Brinzolamide 10 mg/ml Eye Drops, Suspension plus Brimonidine 2 mg/ml Eye Drops, Solution in Pati...
    Medical condition: Patients with open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) PT (Completed) HU (Completed) LT (Completed) DE (Completed) BE (Prematurely Ended) NL (Completed) AT (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-002647-35 Sponsor Protocol Number: C-04-65 Start Date*: 2005-10-06
    Sponsor Name:Alcon Research, Ltd
    Full Title: Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo (Nepafenac Vehicle) for the Prevention and Treatment of Ocular Inflammation and Ocular Pai...
    Medical condition: ocular pain and inflammation associated with cataract extraction and intraocular lens implantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed) ES (Completed) IT (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004127-79 Sponsor Protocol Number: STALMANSHUA Start Date*: 2018-05-09
    Sponsor Name:UZ Leuven
    Full Title: Comparison of treatment with preservative-free versus preserved dexamethasone 0.1% and diclofenac 0.1% eye drops after cataract surgery.
    Medical condition: Treatment after cataract surgery
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-005882-37 Sponsor Protocol Number: 524 Start Date*: 2008-01-17
    Sponsor Name:BAUSCH&LOMB
    Full Title: RANDOMIZED CONTROLLED CLINICAL STUDY ON THE EFFICACY AND TOLERABILITY OF 0.4% HYALURONIC ACID HYPOTONIC EYE DROPS (IALUREX) VS. HYDROXYPROPYL-GUAR EYE DROPS (SYSTANE) IN THE TREATMENT OF DRY EYE SY...
    Medical condition: Dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023350 Keratoconjunctivitis sicca LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-004015-11 Sponsor Protocol Number: MAD2021-07 Start Date*: 2022-11-11
    Sponsor Name:Erasmus MC
    Full Title: Investigator led, double-masked, multicenter, randomized clinical trial for the comparison of Atropine 0.5% versus Atropine 0.05% eye drops for the prevention of myopia progression in Dutch children.
    Medical condition: Myopia
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-000913-35 Sponsor Protocol Number: BECRO/OV/DORZO Start Date*: 2019-05-21
    Sponsor Name:BECRO (Cyprus) Ltd
    Full Title: A Randomized, Observer-blind, two Parallel Group, Multi-center, Clinical Trial for Comparing the Efficacy and Tolerability of Dorzo-Vision® sine Preservative-Free Eye Drops vs. Trusopt® Preservativ...
    Medical condition: Open angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10015919 Eye disorders SOC
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017388-41 Sponsor Protocol Number: LT1225-PII-06/09 Start Date*: 2010-01-14
    Sponsor Name:Laboratoires Théa
    Full Title: Efficacy and Safety Assessment of Azyter® eye drops (T1225) in patients with blepharitis
    Medical condition: Patients with blepharitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002434-13 Sponsor Protocol Number: 01-INSULINAGLAUCOMA-2022 Start Date*: 2023-01-18
    Sponsor Name:Barbara Burgos-Blasco
    Full Title: RANDOMIZED CLINICAL TRIAL DOUBLE BLIND (WITH BLIND EVALUATOR) TO DETERMINE THE EFFECTIVENESS AND SAFETY OF TOPICAL INSULIN IN THE TREATMENT OF DRY EYE IN PATIENTS WITH TOPICAL HYPOTENSIVE DRUGS
    Medical condition: Dry eye disease in glaucoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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