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Clinical trials for Goiter

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    20 result(s) found for: Goiter. Displaying page 1 of 1.
    EudraCT Number: 2005-004451-35 Sponsor Protocol Number: MRTSH01505 Start Date*: 2007-03-13
    Sponsor Name:Genzyme Europe BV
    Full Title: Study to Evaluate the Dose, Safety and Effectiveness of Modified-Release Recombinant Human Thyroid Stimulating Hormone (MRrhTSH) When Used in Conjunction with Radioiodine for the Treatment of Multi...
    Medical condition: Nodular goiter are clinically recognizable enlargements of the thyroid gland characterized by excessive growth and structural and or functional transformation of one or several areas within the nor...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10043808 Thyrotropin LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) FR (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002555-33 Sponsor Protocol Number: 2006.415 Start Date*: 2007-03-14
    Sponsor Name:HOSPICES CIVILS DE LYON
    Full Title: Comparaison de l'efficacité et de la tolérance de différentes doses de méthylprednisolone administrées par voie intraveineuse dans le traitement des formes actives et de sévérité moyenne d'orbitopa...
    Medical condition: orbitopathie basedowienne
    Disease: Version SOC Term Classification Code Term Level
    8.1 10015679 Exophthalmic goiter LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002123-93 Sponsor Protocol Number: MINGO Start Date*: 2009-07-30
    Sponsor Name:Johannes Gutenberg-Universität
    Full Title: Mycophenolate sodium in Graves’ orbitopathy
    Medical condition: Graves' orbitopathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065624 Graves-Basedow disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014361-14 Sponsor Protocol Number: 577/09 Start Date*: 2010-01-13
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: EVALUATION OF FEASIBILITY OF RITUXIMAB BY INTRALESIONAL INJECTION IN PATIENTS WITH GRAVES OPHTALMOPATHY
    Medical condition: GRAVES OPHTALMOPATHY
    Disease: Version SOC Term Classification Code Term Level
    12.1 10065624 Graves-Basedow disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005564-41 Sponsor Protocol Number: CCFZ533X2205 Start Date*: 2016-06-01
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open label study to evaluate the safety and efficacy of 12 week treatment with CFZ533 in patients with Graves' disease
    Medical condition: Graves' disease
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004860 10018706 Graves' disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001910-40 Sponsor Protocol Number: OPHT-120312 Start Date*: 2012-06-06
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: The effect of intravenous glucocorticoids on the tearfilm in eyes with thyroid-associated ophthalmopathy
    Medical condition: Thyroid-associated ophthalmopathy (TAO)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10065624 Graves-Basedow disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022840-19 Sponsor Protocol Number: SEBA Start Date*: 2011-12-30
    Sponsor Name:Universitätsmedizin Mainz
    Full Title: A monocentric, randomized, placebo-controlled double-blind clinical trial to assess the efficacy of Selenium in Morbus Basedow
    Medical condition: Morbus Basedow
    Disease: Version SOC Term Classification Code Term Level
    14.0 10014698 - Endocrine disorders 10004161 Basedow's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001317-33 Sponsor Protocol Number: STAGO Start Date*: 2020-05-14
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA
    Full Title: A Phase II, open-label, ophthalmological external investigator-blinded, single-center, randomized, superiority, no profit, pilot clinical trial to evaluate the effects of atorvastatin on Graves' Or...
    Medical condition: Graves’ orbitopathy is a disabling and disfiguring disease affecting the eyes observed in approximately 25-30% of patients with Graves’ disease. Its clinical manifestations include exophthalmos, in...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10004161 Basedow's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-002894-27 Sponsor Protocol Number: IMVT-1401-2501 Start Date*: 2023-04-03
    Sponsor Name:Immunovant Sciences GmbH
    Full Title: A Proof-of-Concept, Open-label Study to Assess the Safety and Efficacy of Batoclimab and IMVT-1402 in Participants with Graves’ Disease (GD)
    Medical condition: Graves` disease
    Disease: Version SOC Term Classification Code Term Level
    26.0 10014698 - Endocrine disorders 10018706 Graves' disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001941-11 Sponsor Protocol Number: 2021-1798 Start Date*: 2021-09-09
    Sponsor Name:Rijnstate hospital
    Full Title: Ultrasound-guided radiofrequency ablation versus radioactive iodine as treatment for hyperthyroidism caused by solitary autonomous thyroid nodules.
    Medical condition: Patients > 18 years with (subclinical) hyperthyroidism caused by a solitary hyperactive thyroid nodules, either as a solitary hyperactive node in an otherwise normal thyroid gland or as a single hy...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004860 10043753 Thyroid nodule (toxic) LLT
    20.0 100000004860 10043791 Thyrotoxicosis from ectopic thyroid nodule LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-005207-30 Sponsor Protocol Number: 0000 Start Date*: 2017-07-21
    Sponsor Name:HOSPITAL SON ESPASES
    Full Title: CLINICAL TRIAL FOR THE ADMINISTRATION OF PREOPERATIVE VITAMIN D AS PREVENTION IN TRANSITORY HYPOCALCEMIA IN POSTOPERATORY OF TOTAL THYROIDECTOMY
    Medical condition: Transient hypocalcaemia porstoperatoria
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000019580 10047628 Vitamin deficiency LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005606-30 Sponsor Protocol Number: CAM-THY Start Date*: 2012-04-25
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: Keratinocyte Growth Factor - promoting thymic reconstitution and preventing autoimmunity after alemtuzumab (Campath-1H) treatment of multiple sclerosis. CAM-THY
    Medical condition: This trial will test the efficacy of Kepivance in the prevention of new autoimmune diseases in patients who have multiple sclerosis (MS)who are being treated with alemtuzumab.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10058948 Nephritis autoimmune PT
    14.1 10014698 - Endocrine disorders 10049046 Autoimmune thyroiditis PT
    14.1 10021428 - Immune system disorders 10061664 Autoimmune disorder PT
    14.1 10014698 - Endocrine disorders 10068004 Autoimmune hyperthyroidism LLT
    14.1 10005329 - Blood and lymphatic system disorders 10050245 Autoimmune thrombocytopenia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002188-24 Sponsor Protocol Number: 2013-002188-24 Start Date*: 2014-01-16
    Sponsor Name:
    Full Title: REDUCTION OF POST-THYROIDECTOMY TRANSIENT HYPOCALCEMIA WITH CHOLECALCIFEROL 200,000 IU OS ADMINISTERED FOR ONE MONTH BEFORE SURGERY
    Medical condition: Background: 30% of patients undergoing surgery for total thyroidectomy in the first 24 hours may experience a transient hypocalcaemia (serum calcium <8 mg / dl). According to recent studies, pre-s...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10006975 Calcium metabolism disorders HLT
    14.1 10027433 - Metabolism and nutrition disorders 10013296 Bone, calcium, magnesium and phosphorus metabolism disorders HLGT
    14.1 10027433 - Metabolism and nutrition disorders 10020949 Hypocalcemia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-005050-11 Sponsor Protocol Number: SeMMIviD Start Date*: 2019-03-08
    Sponsor Name:A.O. OSPEDALE DI CIRCOLO E FONDAZIONE MACCHI
    Full Title: Effects of Selenium and cholecalciferol on hyperthyroidism due to Graves' disease treated with methimazole: a randomized, clinical, open label, pilot trial
    Medical condition: Graves' disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10020850 Hyperthyroidism PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003515-38 Sponsor Protocol Number: GO-TXATD Start Date*: 2016-02-23
    Sponsor Name:Medical University of Vienna
    Full Title: Prospective Randomized Clinical Trial of Total Thyroidectomy (Tx) versus Thionamides (Anti-Thyroid Drugs) in Patients with Moderate-to-Severe Graves’ Ophthalmopathy - a 1-year Follow-up
    Medical condition: Graves' disease, hyperthyroidism
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001261-25 Sponsor Protocol Number: T3T42017 Start Date*: 2018-01-04
    Sponsor Name:AOU FEDERICO II
    Full Title: PHARMACOLOGICAL, NO PROFIT, PROSPECTIVE RANDOMIZED, DOUBLE-BLIND PLACEBO, CONTROLLED STUDY TO EVALUATE THE EFFICACY OF LEVOTHYROXINE AND LIOTIRONINE (LT4+LT3) IN POST-SURGICAL HYPOTHYROIDISM PATIE...
    Medical condition: POST-SURGICAL HYPOTHYROIDISM
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10036429 Postsurgical hypothyroidism LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001107-38 Sponsor Protocol Number: SESCHI.26371 Start Date*: 2008-05-26
    Sponsor Name:Cefak KG
    Full Title: Dose finding study to investigate efficacy and tolerability of a 6 month oral treatment with selenium in patients with autoimmune thyroiditis: prospective, controlled parallel group study with Cef...
    Medical condition: Autoimmune thyroiditis (Hashimoto-thyroiditis)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10014698 - Endocrine disorders 10019167 Hashimoto's thyroiditis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003506-26 Sponsor Protocol Number: CI-331-19 Start Date*: 2020-03-05
    Sponsor Name:Hospital Universitari Son Espases
    Full Title: Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy
    Medical condition: Patients undergoing total thyroidectomy with visualization of the parathyroid glands under infrared light after intraoperative intravenous injection of 5 mg of indocyanine green to predict the poss...
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004861 10020949 Hypocalcemia LLT
    20.0 100000004865 10043777 Thyroidectomy total LLT
    21.0 10022117 - Injury, poisoning and procedural complications 10080819 Post procedural hypoparathyroidism PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006789-19 Sponsor Protocol Number: NephroD_2021 Start Date*: 2022-05-16
    Sponsor Name:USK w Opolu
    Full Title: Efficacy comparison of two doses of vitamin D3 in critically ill patients undergoing continuous renal replacement therapy - NephroD
    Medical condition: Vitamin D3 deficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10047626 Vitamin D deficiency PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020855-29 Sponsor Protocol Number: E1496/09 Start Date*: 2009-10-16
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI MESSINA
    Full Title: Radioiodine ablation of post-surgical thyroid remnants by recombinant human TSH (rhTSH) in patients with moderately severe and severe Graves' orbithopathy (GO)
    Medical condition: Patients affected with moderately severe and severe GO
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10015919 Eye disorders SOC
    14.1 10014698 - Endocrine disorders 10043739 Thyroid gland disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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