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Clinical trials for Heart valve

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44300   clinical trials with a EudraCT protocol, of which   7354   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    161 result(s) found for: Heart valve. Displaying page 1 of 9.
    1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2009-017625-20 Sponsor Protocol Number: NAROSYD Start Date*: 2010-06-22
    Sponsor Name:Pawel Florkiewicz
    Full Title: Continuous ropivacaine infusion in treatment of postoperative pain in cardiac surgery.
    Medical condition: Research is to verify whether continuous infusion of ropivacaine reduces post-operative analgesic requirement after cardiac surgery.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019316 Heart valve disorders LLT
    12.1 10052895 Coronary artery insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002650-38 Sponsor Protocol Number: Pre65 Start Date*: 2008-07-01
    Sponsor Name:Organisation name was not entered
    Full Title: Vähentääkö pregabaliini opioidikipulääkityksen tarvetta ja kroonisen kivun esiintyvyyttä alle 65-vuotiailla potilailla sydänleikkauksen jälkeen?
    Medical condition: Tutkimukseen otetaan potilaan suostumuksella alle 65-vuotiaita avosydänleikkauk-seen joko koronaariohitus- tai sydämen läppärekonstruktioon tulevia potilaita, jotka leikatataan perfuusioleikkauksena.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011099 Coronary disease LLT
    9.1 10002906 Aortic stenosis LLT
    9.1 10027716 Mitral insufficiency LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-002898-26 Sponsor Protocol Number: CHBX2020/49 Start Date*: 2022-07-01
    Sponsor Name:CHU DE BORDEAUX
    Full Title: Contribution of PET/CT with Gallium 68 citrate (68Ga-PET/CT) for the diagnosis of prosthetic valve infective endocarditis
    Medical condition: Prosthetic valve infective endocarditis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-000077-57 Sponsor Protocol Number: 2021-THORANE-Pharma-001 Start Date*: 2022-06-25
    Sponsor Name:Rigshospitalet
    Full Title: Methadone versus fentanil and oxycodone for post-operative pain reduction in patients undergoing coronary artery bypass grafting and/or valve surgery – a placebo-controlled, double-blind, randomiz...
    Medical condition: We investigate the efficacy of methadonehydrochloride for reducing optoperative opioid requirements, pain scores and improving quality of recovery in patients undergoing heart surgery (i.e. corona...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10008937 Chronic ischemic heart disease, unspecified LLT
    20.0 10007541 - Cardiac disorders 10002911 Aortic valvular disorders HLT
    20.0 10007541 - Cardiac disorders 10061532 Mitral valve disease PT
    20.0 10042613 - Surgical and medical procedures 10062202 Mitral valve repair PT
    20.0 10042613 - Surgical and medical procedures 10027732 Mitral valve replacement PT
    20.0 10042613 - Surgical and medical procedures 10002916 Aortic valve replacement PT
    20.0 10042613 - Surgical and medical procedures 10061652 Aortic valve repair PT
    21.1 10042613 - Surgical and medical procedures 10011077 Coronary artery bypass PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-000111-26 Sponsor Protocol Number: MEIN/10/Ran-Did/002 Start Date*: 2011-07-01
    Sponsor Name:A. MENARINI PHARMA U.K.,
    Full Title: Effect of late sodium current inhibition on MRI measured diastolic dysfunction and myocardial perfusion reserve in aortic stenosis - a proof of concept study.
    Medical condition: Aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-001752-43 Sponsor Protocol Number: SEVO-AIFA-FARM6H73Z9 Start Date*: 2008-07-17
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: CARDIAC PROTECTION WITH SEVOFLURANE IN PATIENTS WITH HIGH RISK UNDERGOING HEART SURGERY. RANDOMIZED, CONTROLLED STUDY.
    Medical condition: adult patients affected by cardiac valve and heart patology undergoing elective surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061406 Cardiac valve disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-005586-40 Sponsor Protocol Number: NL79407.091.21 Start Date*: 2022-05-30
    Sponsor Name:Radboudumc
    Full Title: Colchicine and Inflammation in Aortic Stenosis
    Medical condition: Aortic stenosis (AS) is the most common valvular heart disease in the developed world. The prevalence of aortic sclerosis in the general population is estimated to be 25% at the age of 65 years and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-003973-42 Sponsor Protocol Number: 2007.490/33 Start Date*: 2008-09-04
    Sponsor Name:Hospices Civils de Lyon
    Full Title: PC Pharma CVA : PostConditionnement pharmacologique au cours de la Chirurgie Valvulaire Aortique
    Medical condition: chirurgie valvulaire aortique
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002914 Aortic valve disorders LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003927-13 Sponsor Protocol Number: REAC-TAVI2 Start Date*: 2021-10-15
    Sponsor Name:Fundación Biomédica Galicia Sur
    Full Title: Single antiplatelet therapy with Ticagrelor vs Aspirin after Transcatheter Aortic Valve Implantation: multicenter randomized clinical trial. REAC TAVI 2
    Medical condition: Symptomatic severe aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10077017 TAVI LLT
    20.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    20.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004178-23 Sponsor Protocol Number: T39/2021 Start Date*: 2021-04-14
    Sponsor Name:Turku University Hospital
    Full Title: Ultrasound Guided Repeated Bilateral Transversus Thoracis Muscle Plane Block (TTP) via catheter and postoperative pain in Cardiac Surgery
    Medical condition: cardiac disease necessitating surgery with sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10046972 Valvular heart disease NOS LLT
    20.0 100000004849 10055218 Ischemic heart disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-004295-28 Sponsor Protocol Number: STER-AMVR-01 Start Date*: 2014-11-14
    Sponsor Name:Oulu University Hospital, Department of Anaesthesia
    Full Title: Postoperative pain management after heart valve surgery using parasternal block and PCA Oxycodone
    Medical condition: Mitral or aortic valve disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10049495 Heart valve operation NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003391-39 Sponsor Protocol Number: 9026 Start Date*: 2012-10-26
    Sponsor Name:University Hospital of Montpellier
    Full Title: Ballon aortic valvuloplasty performed without heparin to decrease vascular and bleeding complications of the procedure
    Medical condition: Aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000017-20 Sponsor Protocol Number: ASS-Metamizol-DDI Start Date*: 2018-07-17
    Sponsor Name:Universitäts-Herzzentrum Freiburg • Bad Krozingen
    Full Title: Antiplatelet effect of acetylsalicylic acid in patients after cardiac surgery: Impact of dipyrone (metamizole)
    Medical condition: Antithrombotic therapy after surgical replacement of stenotic heart valve by a bioprosthesis or mitral valve repair
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000518-34 Sponsor Protocol Number: 0107 Start Date*: 2011-10-25
    Sponsor Name:Rikshospitalet
    Full Title: Effect of beta blockade on left ventricular remodeling and function in aortic regurgitation
    Medical condition: The aim of the present study is therefore to assess the effect of a 6 month treatment with beta-blocker on left ventricular remodeling and function in patients with asymptomatic moderate to severe ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10002904 Aortic regurgitation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-001675-32 Sponsor Protocol Number: ARTE Start Date*: 2014-10-20
    Sponsor Name:IUCPQ
    Full Title: Aspirin versus Aspirin + ClopidogRel as Antithrombotic Treatment Following Transcatheter Aortic Valve Implantation with the Edwards Valve. A Randomized Study (the ARTE trial).
    Medical condition: Incidence of death, MI, ischemic stroke/Transient ischemic attack (TIA) or life threatening/major bleeding at 3-month follow-up.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004849 10013118 Diseases of aortic valve LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002015-17 Sponsor Protocol Number: 2016-002015-17 Start Date*: 2017-03-10
    Sponsor Name:Odense University Hospital
    Full Title: Low-flow Low-gradient Aortic Stenosis – Diagnostic Usefullness of Ivabradine
    Medical condition: Aortic valve stenosis with reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002799-18 Sponsor Protocol Number: ICICOR-2017-01 Start Date*: 2017-12-27
    Sponsor Name:José Alberto San Román Calvar
    Full Title: Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI)
    Medical condition: Severe aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-004457-23 Sponsor Protocol Number: 29BRC21.0255 Start Date*: 2022-01-24
    Sponsor Name:CHU de Brest
    Full Title: Impact of local tissue inflammation on intramyocardial conduction pathways post percutaneous valve : evaluation by positron emission tomography
    Medical condition: Aortic stenosis TAVI Cardiac conduction disorders Pacemaker
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10050559 Aortic valve calcification PT
    21.1 10042613 - Surgical and medical procedures 10077015 Transcatheter aortic valve implantation PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001975-30 Sponsor Protocol Number: BAY59-7939/17938 Start Date*: 2016-01-12
    Sponsor Name:Bayer AG
    Full Title: Global multicenter, open-label, randomized, event-driven, active-controlled study comparing a rivAroxaban-based antithrombotic strategy to an antipLatelet-based strategy after transcatheter aortIc ...
    Medical condition: Patients with severe aortic stenosis that require Transcatheter aortic valve replacement are at risk of thrombus formation. Rivaroxaban (oral-anticoagulant) may reduce this risk, without increasing...
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10002916 Aortic valve replacement PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) BE (Prematurely Ended) NO (Prematurely Ended) AT (Prematurely Ended) DK (Prematurely Ended) SE (Prematurely Ended) NL (Prematurely Ended) GB (Prematurely Ended) FR (Prematurely Ended) CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004653-24 Sponsor Protocol Number: ARBAS041218 Start Date*: 2020-06-15
    Sponsor Name:Odense Universitets Hospital
    Full Title: Impact of an Angiotensin Receptor Blocker in Aortic Stenosis – A Randomized Controlled Trial
    Medical condition: Aortic valve stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
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