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Clinical trials for Intracranial pressure monitoring

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    21 result(s) found for: Intracranial pressure monitoring. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-000219-14 Sponsor Protocol Number: 1957 Start Date*: 2008-03-19
    Sponsor Name:North Bristol NHS Trust
    Full Title: Efficacy of 8.4% sodium bicarbonate in adult patients with closed head injuries and intracranial hypertension.
    Medical condition: Raised intracranial pressure after severe head injury.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022764 Intracranial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-005319-66 Sponsor Protocol Number: 2005/W/AN/02 Start Date*: 2006-06-02
    Sponsor Name:Research and Development Office, Royal Infirmary of Edinburgh
    Full Title: A comparative study of HyperHAES (7.2% NACL and 6% hydroxyethyl starch) and 20% mannitol in the treatment of elevated intracranial pressure after brain injry
    Medical condition: elevated intracranial pressure after brain injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001863-35 Sponsor Protocol Number: THAM Start Date*: 2016-06-21
    Sponsor Name:Universitätsklinik für Klinische Pharmakologie, Medizinische Universität Wien
    Full Title: Effects of Tromethamine on Cerebral Oxygenation and Metabolism in Patients Suffering Intractable Intracranial Hypertension – an exploratory study.
    Medical condition: Critically ill patients (SAH, ICB, AVM bleedings, malignant MCA infarcts) under sedation and mechanical ventilation in need of multimodality monitoring, including brain tissue oxygen monitoring and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-000534-20 Sponsor Protocol Number: THAM05 Start Date*: 2005-03-15
    Sponsor Name:Addenbrooke's Hospital NHS Foundation Trust
    Full Title: Influence of brain tissue pH regulation on cerebral oxygenation and metabolism in patients with severe traumatic brain injury.
    Medical condition: Severe traumatic brain injury
    Disease:
    Population Age: Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000584-13 Sponsor Protocol Number: ASSENTE Start Date*: 2007-05-15
    Sponsor Name:OSPEDALE MAGGIORE DI MILANO (IRCCS)
    Full Title: Normothermia in patients with acute cerebral damage
    Medical condition: Subarachnoid hemorrhage, traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    6.1 10060690 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012338-56 Sponsor Protocol Number: VAS203/II/1/03 Start Date*: 2009-07-10
    Sponsor Name:vasopharm GmbH
    Full Title: AN EXPLORATIVE PHASE IIa STUDY TO ASSESS SAFETY, TOLERABILITY, PHARMACODYNAMICS AND PHARMACOKINETICS OF VAS203 IN PATIENTS WITH MODERATE AND SEVERE TRAUMATIC BRAIN INJURY
    Medical condition: Moderate and severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060690 Traumatic brain injury LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-002005-45 Sponsor Protocol Number: OsmoBrain Start Date*: 2007-05-11
    Sponsor Name:A.O. San Gerardo di Monza
    Full Title: Comparative trial between HyperHAES (7.2% sodio cloruro / 6% hydrxyethyl starch) and 20% mannitol for treatmenti intracranial hypertension in traumatic brain injury
    Medical condition: Brain trauma
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029205 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001688-66 Sponsor Protocol Number: SC.14/18-19 Start Date*: 2019-09-09
    Sponsor Name:University of Warwick [...]
    1. University of Warwick
    2. University Hospitals Birmingham NHS Foundation Trust
    Full Title: Sugar or Salt (SOS) trial: Hyperosmolar therapy in traumatic brain injury
    Medical condition: Increased intracranial pressure following traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-004974-16 Sponsor Protocol Number: IL1ra03 Start Date*: 2018-11-08
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMISED CLINICAL DOSE-RANGING STUDY TREATING MODERATE-SEVERE TRAUMATIC BRAIN INJURY PATIENTS WITH RECOMBINANT HUMAN INTERLEUKIN 1 RECEPTOR ANTAGONIST.
    Medical condition: We wish to study the drug Kineret in patients suffering from moderate-to-severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 10029205 - Nervous system disorders 10051288 Central nervous system inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000280-17 Sponsor Protocol Number: 17299425TRM2001 Start Date*: 2007-06-28
    Sponsor Name:Janssen-Cilag International N.V
    Full Title: An Open Label Single and Repeat Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-17299425 in Patients with Traumatic Brain Injury.
    Medical condition: Traumatic Brain Injury (TBI)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-000756-34 Sponsor Protocol Number: 2012.001 Start Date*: 2012-11-02
    Sponsor Name:NeuroVive Pharmaceutical AB
    Full Title: Copenhagen Head Injury Ciclosporin (CHIC) Study: An open-label, uncontrolled Phase II -study to investigate pharmacokinetics, safety and biomarkers of effectiveness of NeuroSTAT® (ciclosporin) i...
    Medical condition: Severe Traumatic Brain Injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-003410-12 Sponsor Protocol Number: RG_19-169 Start Date*: 2020-12-16
    Sponsor Name:University of Birmingham
    Full Title: Pregnancy ANtihypertensive Drugs: which Agent is best?
    Medical condition: Hypertension in pregnancy (chronic hypertension, gestational hypertension or pre-eclampsia)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-018283-16 Sponsor Protocol Number: BHR-100-301 Start Date*: 2010-09-24
    Sponsor Name:BHR Pharma, LLC
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study to Investigate the Efficacy and Safety of Progesterone in Patients with Severe Traumatic Brain Injury
    Medical condition: Severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10060690 Traumatic brain injury LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) GB (Completed) CZ (Completed) NL (Completed) AT (Completed) DE (Completed) ES (Completed) IT (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003697-27 Sponsor Protocol Number: CS2/713 Start Date*: 2020-05-04
    Sponsor Name:AOU CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO
    Full Title: Effect of inhalatory sedation on cerebral perfusion in subarchnoid hemorrhage
    Medical condition: Patients with non traumatic subarachnoid hemorrhage (WFNS = 3 -5)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003368-29 Sponsor Protocol Number: VAS203/III/1/04 Start Date*: 2016-05-31
    Sponsor Name:vasopharm GmbH
    Full Title: EFFICACY OF VAS203 IN PATIENTS WITH MODERATE AND SEVERE TRAUMATIC BRAIN INJURY. A confirmatory, placebo-controlled, randomised, double blind, multi-centre study.
    Medical condition: Moderate and severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000586-33 Sponsor Protocol Number: 19-PP-15 Start Date*: 2021-07-21
    Sponsor Name:CHU de Nice
    Full Title: Effect of molar sodium lactate infusion on cerebral hemodynamic in patients with severe subarachnoid hemorrhage: a multicenter double-blind randomized controlled study
    Medical condition: Subarachnoid hemorrhage caused by rupture of cerebral aneurysm
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-006694-39 Sponsor Protocol Number: ASF-CP02-001 Start Date*: 2022-07-08
    Sponsor Name:Lantmännen Medical AB
    Full Title: An open-label, historical cohort control study to evaluate the safety and tolerability of AF-16 in patients with cerebral oedema caused by traumatic brain injury (TBI)
    Medical condition: Cerebral oedema caused by traumatic brain injury (TBI)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 100000004852 10008127 Cerebral oedema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005707-42 Sponsor Protocol Number: A090624 Start Date*: 2007-07-23
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: A single centre phase II study of Interleukin 1 receptor antagonist in the treatment of severe Traumatic Brain Injury
    Medical condition: Severe Traumatic Brain Injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060690 Traumatic brain injury LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003144-23 Sponsor Protocol Number: PANDA Start Date*: 2014-02-03
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St Thomas' NHS Foundation Trust
    Full Title: Pregnancy And chronic hypertension: NifeDipine or labetalol as Antihypertensive treatment
    Medical condition: Chronic hypertension in pregnancy
    Disease: Version SOC Term Classification Code Term Level
    16.1 10047065 - Vascular disorders 10036695 Primary hypertension LLT
    16.1 10047065 - Vascular disorders 10039834 Secondary hypertension PT
    16.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002620-17 Sponsor Protocol Number: B7461001 Start Date*: 2014-03-21
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: Phase 1/2 study of PF-06463922 (an ALK/ROS1 tyrosine kinase inhibitor) in patients with advanced non-small cell lung cancer harboring specific molecular alterations.
    Medical condition: Anaplastic Lymphoma Kinase (ALK)-positive (ALK+) or ROS oncogene 1 (ROS1)-positive (ROS1+) advanced non-small cell lung cancer (NSCLC).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10066490 Progression of non-small cell lung cancer LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059515 Non-small cell lung cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) GB (GB - no longer in EU/EEA) IT (Completed) BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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