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Clinical trials for Ivabradine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    49 result(s) found for: Ivabradine. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2019-000661-20 Sponsor Protocol Number: ICO Start Date*: 2019-05-31
    Sponsor Name:Vilnius University Hospital Santaros klinikos
    Full Title: Ivabradine to prevent anthracycline-induced cardiotoxicity: a prospective randomized open label clinical trial.
    Medical condition: Cancers treated with anthracyclines: leukemias, limphomas, breast, stomach, uterine, ovarian, lung.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000103-34 Sponsor Protocol Number: CL2-16257-062 Start Date*: 2005-07-13
    Sponsor Name:Institut de Recherches Internationales Servier [...]
    1. Institut de Recherches Internationales Servier
    2. Laboratorios Servier S.L. (For Spain only)
    Full Title: Evaluation of the effects of 3 successive oral dosages (2.5; 5; 7.5 mg b.i.d.) of ivabradine in patients with stable moderate to severe systolic chronic heart failure treated with beta-blockers. A ...
    Medical condition: Chronic systolic heart failure
    Disease: Version SOC Term Classification Code Term Level
    3.3 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001689-13 Sponsor Protocol Number: CL3-16257-098 Start Date*: 2012-11-08
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Safety of oral chronic administration of ivabradine modified release formulation compared to ivabradine immediate release formulation in patients with chronic heart failure and left ventricular sys...
    Medical condition: Moderate to severe chronic heart failure and reduced left ventricular ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) DE (Completed) LV (Completed) LT (Completed) EE (Completed) ES (Completed) BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000708-18 Sponsor Protocol Number: CL3-16257-063 Start Date*: 2006-08-23
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effects of ivabradine on cardiovascular events in patients with moderate to severe chronic heart failure and left ventricular systolic dysfunction. A three-year randomised double-blind placebo-cont...
    Medical condition: cardiac failure chronic
    Disease: Version SOC Term Classification Code Term Level
    9.0 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) BE (Completed) DE (Completed) NL (Completed) LT (Completed) DK (Completed) LV (Completed) FI (Completed) SI (Completed) CZ (Completed) EE (Completed) SK (Completed) IE (Completed) GB (Completed) BG (Completed) IT (Completed) PT (Completed) GR (Completed) AT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-000191-15 Sponsor Protocol Number: CORO-RYC-001 Start Date*: 2018-06-13
    Sponsor Name:IRICYS- Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal
    Full Title: Effectiveness and Safety on Cardiac Frecuency Control With Ivabradine on the Cardiogenic Shock. (ES-FISH)
    Medical condition: Cardiogenic Shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006793-28 Sponsor Protocol Number: CL3-16257-078 Start Date*: 2008-09-18
    Sponsor Name:Institut de Recherches Internationales Servier (I.R.I.S)
    Full Title: Effects of a 10 or 15 mg single intravenous bolus of ivabradine versus placebo on heart rate control during a multislice computed tomography coronary angiography for the evaluation of coronary arte...
    Medical condition: Heart rate control during a MultiSlice Computed Tomography Coronary Angiography (MST CA) for the evaluation of Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    11.0 10060804 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) GB (Completed) BE (Completed) PT (Completed) HU (Completed) ES (Completed) DE (Completed) FR (Completed) DK (Completed) IT (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-001292-39 Sponsor Protocol Number: CL2-16257-090 Start Date*: 2011-09-28
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Determination of the efficacious and safe dose of ivabradine in paediatric patients with dilated cardiomyopathy and symptomatic chronic heart failure aged from 6 months to less than 18 years. A ra...
    Medical condition: Paediatric dilated cardiomyopathy and symptomatic chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) BE (Completed) SE (Completed) DE (Completed) PT (Completed) IT (Completed) HU (Completed) BG (Completed) DK (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-004779-38 Sponsor Protocol Number: CL3-16257-102 Start Date*: 2013-04-16
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effects of ivabradine on plaque burden, morphology and composition in patients with clinically indicated coronary angiography. A randomised double-blind placebo-controlled international multicentre...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) GB (Prematurely Ended) ES (Prematurely Ended) PT (Prematurely Ended) SK (Prematurely Ended) BE (Prematurely Ended) DE (Completed) CZ (Completed) HU (Prematurely Ended) PL (Prematurely Ended) SE (Prematurely Ended) NO (Prematurely Ended) DK (Prematurely Ended) GR (Prematurely Ended) FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-001936-23 Sponsor Protocol Number: BRAKE-AF Start Date*: 2018-09-21
    Sponsor Name:Dr. Adolfo Fontenla Cerezuela
    Full Title: A multicenter, randomized, open-label, phase III clinical trial to compare the efficacy and safety of Ivabradine versus Digoxine in the chronic control of heart rate in patients with permanent atri...
    Medical condition: Heart rate control in patients with chronic atrial fibrillation.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10071668 Permanent atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-002742-20 Sponsor Protocol Number: CL2-16257-101 Start Date*: 2013-03-20
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effect of ivabradine versus placebo on cardiac function, exercise capacity, and neuroendocrine activation in patients with Chronic Heart Failure with Preserved left ventricular Ejection Fraction A...
    Medical condition: Heart failure with preserved left ventricular ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) PT (Completed) IT (Completed) DE (Completed) BE (Completed) GB (Completed) NL (Completed) ES (Completed) CZ (Completed) AT (Completed) SI (Completed)
    Trial results: View results
    EudraCT Number: 2011-003933-32 Sponsor Protocol Number: A092358 Start Date*: 2011-09-21
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: A randomised, blind, placebo controlled crossover study of the influence of the HCN channel-blocker ivabradine on the symptoms of neuropathic pain
    Medical condition: Neuropathic Pain
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10029223 Neuralgia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003801-24 Sponsor Protocol Number: P160925J Start Date*: 2019-11-06
    Sponsor Name:Assistance Publique - Hôpitaux de Paris
    Full Title: A multicenter, prospective, randomized, placebo-controlled, double-blind, multi-arm, multi-stage clinical trial of Ivabradine for heart Rate control In Septic shock
    Medical condition: Trial subjects are adult patients with septic shock.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-003902-29 Sponsor Protocol Number: EASI-Child Start Date*: 2020-04-30
    Sponsor Name:IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA
    Full Title: Early Administration of Ivabradine in Children with Heart Failure.
    Medical condition: Acute hearth failure in dilated cardiomyopathy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-011360-10 Sponsor Protocol Number: CL3-16257-083 Start Date*: 2009-10-13
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efectos de ivabradina en pacientes con arteriopatía coronaria estable sin insuficiencia cardíaca clínica. Estudio multicéntrico, internacional, aleatorizado, doble ciego, controlado con placebo St...
    Medical condition: Arteriopatia Coronaria Estable Stable coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    12.0 10011078 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) PT (Completed) GB (Completed) NL (Completed) FI (Completed) LV (Completed) HU (Completed) CZ (Completed) SK (Completed) IE (Completed) BE (Completed) FR (Completed) LT (Completed) DE (Completed) AT (Completed) SE (Completed) IT (Completed) GR (Completed) EE (Completed) SI (Completed) BG (Completed) DK (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2012-001668-31 Sponsor Protocol Number: CL3-16257-097 Start Date*: 2012-10-05
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Safety of oral chronic administration of ivabradine modified release formulation compared to ivabradine immediate release formulation, in patients with stable coronary artery disease. A 6 to 12-mon...
    Medical condition: Stable coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    16.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) DE (Completed) SK (Completed) NL (Completed) ES (Completed) BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003034-16 Sponsor Protocol Number: FNOL-IVA-ICD Start Date*: 2014-05-12
    Sponsor Name:University Hospital Olomouc
    Full Title: Antiarrhythmic and antiremodelation effects of ivabradin in ICD carriers
    Medical condition: Heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001201-42 Sponsor Protocol Number: 4-001-LVS Start Date*: 2008-06-01
    Sponsor Name:POLICLINICO SAN DONATO IRCSS
    Full Title: Clinical trial on the use of ivabradine in patients with inappropriate sinus tachycardia
    Medical condition: Inappropriate sinus tachycardia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003133 Arrythmia sinus LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005475-17 Sponsor Protocol Number: CL3-16257-067 Start Date*: 2008-01-04
    Sponsor Name:Institut de Recherches Internationales Servier (I.R.I.S.)
    Full Title: Long-term (3 years) ophthalmic safety and cardiac efficacy and safety of ivabradine administered orally at the therapeutic doses (2.5/5/7.5 mg b.i.d.) on top of anti-anginal background therapy, to ...
    Medical condition: Stable angina pectoris
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10049194 Stable angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) PT (Completed) BE (Completed) FI (Completed) GB (Prematurely Ended) HU (Completed) SE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007287-42 Sponsor Protocol Number: IVA-TCMD Start Date*: 2009-04-17
    Sponsor Name:AZIENDA OSPEDALIERA DI PARMA
    Full Title: Ivabradine in multislice CT: comparison with metoprolol in the reduction of motion artefacts and in the improvement of diagnostic care.
    Medical condition: patients with coronary arteries desease, who need Tc multislice for diagnostic reasons
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-001959-11 Sponsor Protocol Number: CL3-16257-056 Start Date*: 2005-04-20
    Sponsor Name:Institut de Recherches Internationales
    Full Title: Effects of ivabradine on cardiovascular events in patients with stable coronary artery disease and left ventricular systolic dysfunction. A three-year randomised double-blind placebo-controlled int...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    7.0 10011078 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) FI (Completed) LV (Completed) IT (Completed) CZ (Completed) SK (Completed) GB (Completed) DK (Completed) AT (Completed) SE (Completed) EE (Completed) DE (Completed) IE (Completed) ES (Completed)
    Trial results: View results
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