- Trials with a EudraCT protocol (1,059)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (57)
1,059 result(s) found for: Methotrexate.
Displaying page 1 of 53.
EudraCT Number: 2018-004287-56 | Sponsor Protocol Number: CHUBX2016/44 | Start Date*: 2019-11-21 | |||||||||||
Sponsor Name:CHU de Bordeaux | |||||||||||||
Full Title: Randomized placebo-controlled trial comparing Methotrexate vs. Methotrexate/Metformin association in rheumatoid arthritis patients: METorMET² study | |||||||||||||
Medical condition: rheumatoid arthritis (RA) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2004-002157-30 | Sponsor Protocol Number: 01-03-TL-715-005 | Start Date*: 2004-12-01 |
Sponsor Name:Takeda Europe R&D Centre Ltd. (TEuR&D) | ||
Full Title: A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of Oral TAK-715 in the Treatment of the Signs and Symptoms of Rheumatoid Arthritis | ||
Medical condition: Rheumatoid Arthritis | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: FI (Completed) DK (Completed) SK (Completed) | ||
Trial results: View results |
EudraCT Number: 2004-002662-38 | Sponsor Protocol Number: ZD1839IL/0704 | Start Date*: 2004-11-12 |
Sponsor Name:AstraZeneca AB | ||
Full Title: A PHASE III RANDOMISED, STRATIFIED, PARALLEL-GROUP, MULTI-CENTRE, COMPARATIVE STUDY OF ZD1839 (IRESSA®) 250 MG AND 500 MG VERSUS METHOTREXATE FOR PREVIOUSLY TREATED PATIENTS WITH SQUAMOUS CELL CARC... | ||
Medical condition: squamous cell carcinoma of the head and neck | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: LV (Completed) LT (Completed) EE (Completed) | ||
Trial results: View results |
EudraCT Number: 2020-000462-41 | Sponsor Protocol Number: MTXRA | Start Date*: 2021-02-09 |
Sponsor Name:Västerbotten county | ||
Full Title: Efficacy, tolerability and preferences of peroral or subcutaneous methotrexate in patients with early rheumatoid arthritis – a randomized register based multicenter study | ||
Medical condition: Rheumatoid arthritis | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: SE (Trial now transitioned) | ||
Trial results: (No results available) |
EudraCT Number: 2015-000591-97 | Sponsor Protocol Number: CLSG-CNS-001 | Start Date*: 2015-06-03 | |||||||||||
Sponsor Name:Kooperativní lymfomová skupina, o.s. | |||||||||||||
Full Title: Study evaluating relapses in central nervous system in patients with diffuse large B-cell lymphoma treated with chemotherapy with or without CNS prophylaxis. Multicentric, prospective randomized p... | |||||||||||||
Medical condition: Diffuse large B-cell lymphoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: CZ (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-003334-27 | Sponsor Protocol Number: M13-545 | Start Date*: 2015-12-11 | |||||||||||
Sponsor Name:AbbVie Deutschland GmbH & Co. KG | |||||||||||||
Full Title: A Phase 3, Randomized, Double-Blind Study Comparing Upadacitinib (ABT-494) Once Daily Monotherapy to Methotrexate (MTX) Monotherapy in MTX-Naïve Subjects with Moderately to Severely Active Rheumato... | |||||||||||||
Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SK (Completed) SI (Completed) ES (Ongoing) GR (Completed) LT (Completed) BE (Completed) CZ (Completed) IE (Completed) LV (Completed) PL (Completed) GB (GB - no longer in EU/EEA) PT (Completed) HU (Completed) FI (Prematurely Ended) RO (Ongoing) HR (Completed) BG (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-003753-56 | Sponsor Protocol Number: 04WH19 | Start Date*: 2005-05-31 |
Sponsor Name:King's College Hospital NHS Foundation Trust | ||
Full Title: Randomised double blind control trial of single dose methotrexate versus expectant management in women with tubal ectopic pregnancy | ||
Medical condition: Tubal ectopic pregnancy | ||
Disease: | ||
Population Age: Adults | Gender: Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2004-000922-59 | Sponsor Protocol Number: IM101-043 | Start Date*: 2004-12-01 |
Sponsor Name:Bristol Myers Squibb International Corporation | ||
Full Title: A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Comparative Study of Abatacept or Infliximab in Combination with Methotrexate in Controlling Disease Activity in Subjects wit... | ||
Medical condition: Rheumatoid Arthrithis, Nos | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: SE (Completed) DK (Completed) CZ (Completed) ES (Completed) | ||
Trial results: Removed from public view |
EudraCT Number: 2016-002344-16 | Sponsor Protocol Number: RR16/209 | Start Date*: 2018-06-28 |
Sponsor Name:University of Leeds | ||
Full Title: Targeted treatment early with etanercept (biosimilar) plus methotrexate or methotrexate with T2T care for DMARD-naïve early RA patients. A prospective, longitudinal cohort study with an embedded pi... | ||
Medical condition: Rheumatoid Arthritis | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: GB (GB - no longer in EU/EEA) | ||
Trial results: (No results available) |
EudraCT Number: 2004-000563-96 | Sponsor Protocol Number: 0881A-101548 | Start Date*: 2004-11-12 |
Sponsor Name:Wyeth Pharmaceuticals | ||
Full Title: A 24-MONTH, RANDOMIZED, DOUBLE-BLIND, TWO PERIOD STUDY TO EVALUATE THE EFFICACY AND SAFETY OF THE COMBINATION OF ETANERCEPT AND METHOTREXATE AND METHOTREXATE ALONE IN SUBJECTS WITH ACTIVE EARLY RHE... | ||
Medical condition: Rheumatoid Arthritis | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: HU (Completed) SE (Completed) NO (Completed) FI (Completed) ES (Completed) AT (Completed) IE (Completed) IT (Completed) DK (Completed) | ||
Trial results: View results |
EudraCT Number: 2004-000106-41 | Sponsor Protocol Number: CXA100750 | Start Date*: 2004-09-07 |
Sponsor Name:GlaxoSmithKline Research & Development Ltd | ||
Full Title: A study to investigate the effect of GW406381 on methotrexate pharmacokinetics in patients treated with methotrexate for rheumatoid arthritis | ||
Medical condition: The patients entering the trial have rheumatoid arthritis although treatment of the disease itself is not under investigation in this study. | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: SE (Completed) | ||
Trial results: View results |
EudraCT Number: 2020-001899-14 | Sponsor Protocol Number: UKER-ATTRACTOR-01 | Start Date*: 2020-08-18 | |||||||||||
Sponsor Name:Universitätsklinikum Erlangen | |||||||||||||
Full Title: A prospective, randomized, controlled, open label, assessor-blinded, parallel-group Phase III clinical trial to evaluate the impact of tapering systemic immunosuppressive therapy in a treat-to-targ... | |||||||||||||
Medical condition: Psoriatic arthritis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2006-006728-20 | Sponsor Protocol Number: TAYS1002 | Start Date*: 2007-05-31 | |||||||||||
Sponsor Name:Moorfields Eye Hospital | |||||||||||||
Full Title: The use of intraocular methotrexate to treat uveitis: a safety and efficacy study | |||||||||||||
Medical condition: Uveitis (inflammatory eye disease) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-004148-31 | Sponsor Protocol Number: PREDMETH_NL71782.078.19 | Start Date*: 2020-02-26 |
Sponsor Name:Erasmus Medisch Centrum Dept. of Pulmonology | ||
Full Title: The PREDMETH trial: Effectiveness of methotrexate versus prednisone as first-line therapy for pulmonary sarcoidosis – A randomized controlled trial | ||
Medical condition: pulmonary sarcoidosis | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Trial now transitioned) | ||
Trial results: (No results available) |
EudraCT Number: 2014-004869-24 | Sponsor Protocol Number: 20130207 | Start Date*: 2015-12-09 | |||||||||||
Sponsor Name:Amgen Inc. | |||||||||||||
Full Title: A Multicenter Double-Blind, Randomized Controlled Study of Etanercept and Methotrexate in Combination or as Monotherapy in Subjects With Psoriatic Arthritis. | |||||||||||||
Medical condition: Psoriatic arthritis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: LV (Completed) GR (Completed) GB (Completed) PT (Completed) HU (Completed) CZ (Completed) BG (Completed) PL (Completed) ES (Completed) FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-004868-38 | Sponsor Protocol Number: 20110186 | Start Date*: 2016-01-26 | |||||||||||
Sponsor Name:Amgen Inc. | |||||||||||||
Full Title: A Randomized Withdrawal Double-blind Study of Etanercept Monotherapy Compared to Methotrexate Monotherapy for Maintenance of Remission in Subjects With Rheumatoid Arthritis. | |||||||||||||
Medical condition: Rheumatoid arthritis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GR (Completed) CZ (Completed) HU (Completed) PT (Completed) BG (Completed) ES (Completed) FR (Completed) DE (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-003054-26 | Sponsor Protocol Number: TAK-783/EC201 | Start Date*: 2007-08-31 | |||||||||||
Sponsor Name:Takeda Global R&D (Europe) Ltd | |||||||||||||
Full Title: A Randomized, Double-Blind, Placebo-Controlled Proof of Concept Study to Evaluate the Safety and Efficacy of Oral TAK-783 in the Treatment of the Signs and Symptoms of in Subjects with Rheumatoid A... | |||||||||||||
Medical condition: Rheumatoid arthritis (RA) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: CZ (Completed) LV (Completed) HU (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-008171-34 | Sponsor Protocol Number: CNTO1275PSO4004 | Start Date*: 2009-09-01 | |||||||||||
Sponsor Name:Janssen-Cilag EMEA Medical Affairs | |||||||||||||
Full Title: AN EXPLORATORY TRIAL TO ASSESS NATURALISTIC SAFETY AND EFFICACY OUTCOMES IN PATIENTS TRANSITIONED TO USTEKINUMAB FROM PREVIOUS METHOTREXATE THERAPY (TRANSIT) | |||||||||||||
Medical condition: moderate to severe plaque psoriasis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) DE (Completed) AT (Completed) SE (Completed) BE (Completed) HU (Completed) LT (Completed) DK (Completed) FI (Completed) FR (Completed) SK (Completed) PT (Completed) ES (Completed) GB (Completed) BG (Completed) GR (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-005260-20 | Sponsor Protocol Number: ML28096 | Start Date*: 2012-06-28 | |||||||||||
Sponsor Name:Roche Products Limited | |||||||||||||
Full Title: Randomised, Phase IV, placebo-controlled, comparative study to evaluate the efficacy and safety of tapering methotrexate (MTX) dosage versus maintaining the dosage in patients with severe active rh... | |||||||||||||
Medical condition: Adult Rheumatoid Arthritis (RA) | |||||||||||||
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Population Age: | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-005214-19 | Sponsor Protocol Number: S127AMCGolimumabPsA | Start Date*: 2013-06-20 |
Sponsor Name:Academic Medical Center, Department of Rheumatology | ||
Full Title: A randomized, double-blind, placebo-controlled trial of golimumab+methotrexate versus methotrexate alone in methotrexate-naïve patients with psoriatic arthritis | ||
Medical condition: active psoriatic arthritis | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Completed) | ||
Trial results: (No results available) |
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