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Clinical trials for Muscles

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    283 result(s) found for: Muscles. Displaying page 1 of 15.
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    EudraCT Number: 2011-004636-66 Sponsor Protocol Number: KP-2011-0077 Start Date*: 2011-12-05
    Sponsor Name:Uppsala University Hospital
    Full Title: Single-blinded randomized trial of Botulinumtoxin A (Vistabel®) and its objective paralytic effect in the facial muscles of healthy women: development of new neurophysiological measurements.
    Medical condition: The treatment of glabellar lines in healthy women by muscle paralysis from injection of botulinum toxin
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006776-37 Sponsor Protocol Number: Nij2007 Start Date*: 2007-05-14
    Sponsor Name:Radboud University Nijmegen Medical Center
    Full Title: Towards the assessment of metabolic biomarkers and creatine uptake and turnover in skeletal muscles of patients with Facioscapulohumeral muscular dystrophy using MR spectroscopy
    Medical condition: Healthy volunteers. Later the protocol will be applied to Facioscapular humeral dystrophy and/or other muscular dystrophies in general.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011328 Creatine LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000788-30 Sponsor Protocol Number: 1.2022 Start Date*: 2023-04-13
    Sponsor Name:Uzdrowisko Kamień Pomorski S.A.
    Full Title: Evaluation of the effectiveness of Methocarbamol in the treatment of spasticity in people with spinal cord injury.
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-006255-34 Sponsor Protocol Number: BN43703 Start Date*: 2022-08-26
    Sponsor Name:F.Hoffmann-La Roche Ltd
    Full Title: A PHASE II, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY TO EVALUATE THE PHARMACODYNAMICS, SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF RO7204239 IN PARTICIPANTS WITH ...
    Medical condition: Facioscapulohumeral muscular dystrophy (FSHD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-004215-35 Sponsor Protocol Number: TENPET Start Date*: 2005-01-19
    Sponsor Name:Turku PET Centre
    Full Title: Influence of muscle specific activation on regional glucose uptake in the human Achilles tendon
    Medical condition: The combined forces generated by the triceps surae muscles causes non-uniform strain within the human triceps aponeuroses. This may cause non-uniform tendon force that would result in intratendinou...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001296-23 Sponsor Protocol Number: 61409 Start Date*: 2019-06-03
    Sponsor Name:Radboudumc
    Full Title: The efficacy of botulinum toxin A injection in pelvic floor muscles in chronic pelvic pain patients: a double-blinded randomised controlled trial
    Medical condition: Patients with >6 months or recurrent episodes of abdomino-perineo-pelvic pain, hypersensitivity or discomfort often associated with elimination changes, and sexual dysfunction in the absence of org...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001250-41 Sponsor Protocol Number: KOLD Start Date*: 2015-04-15
    Sponsor Name:Region Östergötland
    Full Title: THE IMPACT OF VITAMIN D ON PHYSICAL TRAINING OF VITAMIN D DEFICIENT PATIENTS WITH COPD: A PROSPECTIVE RANDOMIZED PLACEBO-CONTROLLED DOUBLE-BLIND MULTI-CENTRE STUDY
    Medical condition: Patients with chronic obstructive pulmonary disease (COPD) and concomitant vitamin D deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023006-12 Sponsor Protocol Number: 2010-362 Start Date*: 2011-01-14
    Sponsor Name:Professor Krzysztof Tadeusz Drzewiecki
    Full Title: Lipofilling with MSC enriched fat, a permanent autologous filler?
    Medical condition: Patients who have a need of reconstruction after surgery, eg. after mastectomy. The purpose of this clinical trial, is to make a reproducible and safe method for fat transplantation, that can be us...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10037773 Radical mastectomy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-004474-42 Sponsor Protocol Number: V3_06082015 Start Date*: 2015-05-07
    Sponsor Name:Copenhagen University Hospital at Hvidovre
    Full Title: Treatment of equinus gait caused by dynamic tightening of the calf muscles in children with cerebral palsy. A randomized, placebo controlled Botulinum toxin type A volume/response study.
    Medical condition: Treatment of equinus gait caused by dynamic tightening of the calf muscles in children with cerebral palsy.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10015112 Equinus deformity of foot, acquired LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004102-42 Sponsor Protocol Number: EP-DICLO/2G-01-2015 Start Date*: 2017-06-06
    Sponsor Name:Epifarma S.r.l.
    Full Title: Randomized, multi-center, double-blind, three-armed trial, to evaluate the non-inferiority, efficacy and safety of diclofenac2% gel (Test) versus the originator diclofenac2% gel chosen as Referenc...
    Medical condition: Acute traumatic events (injury/contusion) classified from mild to moderate pain at rest to the joints, muscles, tendons and ligaments
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10022117 Injury, poisoning and procedural complications SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) LV (Completed) LT (Completed) HU (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002302-46 Sponsor Protocol Number: IMIB-TCIM/ELAII-2019-01 Start Date*: 2019-10-23
    Sponsor Name:Fundación para la Formación e Investigación Sanitarias de la Región de Murcia
    Full Title: Phase II clinical trial of intramuscular infusion of autologous bone marrow stem cells in patients with amyotrophic lateral sclerosis
    Medical condition: Amyotrophic Lateral Sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001034-10 Sponsor Protocol Number: SativexStroke Start Date*: 2016-12-07
    Sponsor Name:IRCCS-A.O.U. SAN MARTINO-IST
    Full Title: Neurophysiological assessment of the effect of Sativex (THC/CBD oromucosal spray) as add-on to treat spasticity following stroke
    Medical condition: Spasticity following stroke
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10041416 Spasticity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020482-24 Sponsor Protocol Number: 1 Start Date*: 2014-10-23
    Sponsor Name:Department of Endocrinology, Sahlgrenska University Hospital
    Full Title: Ga-68-DOTATOC -PET in the management of pituitary tumours (PA) and Thyroid associated ophtalmopathy (TAO)
    Medical condition: In this trial with Ga-68 DOTATOC two groupd of patients will be investigated - patients with pituitary adenoma (PA) and patients with thyroid associateed ophtalmopathy (TAO). As the eye muscles and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001779-29 Sponsor Protocol Number: EP-DICLO/G-01-2015 Start Date*: 2016-12-15
    Sponsor Name:Epifarma s.r.l.
    Full Title: Randomized, double-blind, parallel group, placebo-controlled, multicenter clinical trial to evaluate efficacy and safety of diclofenac 1% gel produced by Epifarma s.r.l. (Test) versus the originato...
    Medical condition: Patients with acute painful and flogistic (inflammatory) disease due to acute traumatic events (injury/contusion) of joints, muscles, tendons and ligaments
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000710-37 Sponsor Protocol Number: ZLB06_006CR Start Date*: 2007-12-10
    Sponsor Name:CSL Behring AG
    Full Title: A multicentre study of subcutaneous immunoglobulin in patients with Multifocal Motor Neuropathy (MMN)
    Medical condition: Patients with multifocal motor neuropathy, who are treated successful with IVIG and had a stable IVIG treatment schedule for at least 12 weeks prior to screening.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065579 Multifocal motor neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002086-20 Sponsor Protocol Number: A-94-52120-098 Start Date*: 2005-03-09
    Sponsor Name:Ipsen Pharma GmbH
    Full Title: Open, multicentre study on the equivalent efficacy and safety of Botulinum toxin A (500 Units Dysport®) in the treatment of heterogeneous forms of cervical dystonia
    Medical condition: Cervical dystonia (CD), one of the most common forms of focal dystonia, is characterised by an altered head posture, pain in the the neck and shoulder region and hypertrophy of the concerned muscle...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001629-41 Sponsor Protocol Number: DSC/15/2357/53 Start Date*: 2018-11-15
    Sponsor Name:ITALFARMACO S.P.A.
    Full Title: A randomised, double-blind, placebo-controlled study to evaluate the micro-macroscopic effects on muscles, the safety and tolerability, and the efficacy of givinostat in patients with Becker Muscu...
    Medical condition: Distrofia Muscolare di Becker (DMB)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10059117 Becker's muscular dystrophy PT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004497-33 Sponsor Protocol Number: Protocol_Dysport_v3__13.12.2017 Start Date*: 2018-03-06
    Sponsor Name:Copenhagen University Hospital at Hvidovre
    Full Title: Measuring effects on pain and quality of life after Dysport® injection in children with cerebral palsy
    Medical condition: Muscle pain in the extremities due to spasticity in children with cerebral palsy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10028322 Muscle pain LLT
    20.0 100000004852 10041418 Spasticity muscle LLT
    20.1 100000004850 10021745 Infantile cerebral palsy, unspecified LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-002539-32 Sponsor Protocol Number: The_WE_Study Start Date*: 2015-03-23
    Sponsor Name:St. Olavs University Hospital
    Full Title: The WE Study - Walking Easier with cerebral palsy
    Medical condition: cerebral palsy
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004850 10021740 Infantile cerebral palsy LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NO (Completed) FR (Ongoing) PL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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