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Clinical trials for NOTES

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    162 result(s) found for: NOTES. Displaying page 1 of 9.
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    EudraCT Number: 2014-004249-29 Sponsor Protocol Number: DALMATION/7212 Start Date*: 2015-10-30
    Sponsor Name:The Newcastle Upon Tyne Hospitals NHS Foundation Trust
    Full Title: An Open Label, Non-Randomised, Phase II study to Determine if Dabigatran and its Metabolites are Detectable in Breast Milk Following Oral Administration to Non-Breastfeeding Mothers
    Medical condition: Future use for VTE prophylaxis.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000851-15 Sponsor Protocol Number: UoB1581 Start Date*: 2012-10-25
    Sponsor Name:University of Bristol
    Full Title: What is the clinical and cost effectiveness of oral steroids in the treatment of acute lower respiratory tract infection (LRTI)? A placebo controlled randomised trial
    Medical condition: Acute lower respiratory tract infection/bronchitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10006451 Bronchitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-000685-11 Sponsor Protocol Number: PR-30-5011-C Start Date*: 2013-09-29
    Sponsor Name:TESARO Inc.
    Full Title: A Phase 3 Randomized Double-Blind Trial of Maintenance with Niraparib Versus Placebo in Patients with Platinum Sensitive Ovarian Cancer
    Medical condition: Platinum Sensitive Ovarian Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033128 Ovarian cancer PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed) DE (Completed) AT (Completed) GB (GB - no longer in EU/EEA) DK (Completed) IT (Completed) HU (Completed) ES (Ongoing) BE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-001234-17 Sponsor Protocol Number: A3191084 Start Date*: 2006-06-15
    Sponsor Name:Pfizer Limited
    Full Title: Double-blind, triple dummy, parallel-group, randomized, six-month study to compare celecoxib (200 mg BID) with diclofenac SR (75 mg BID) plus omeprazole (20 mg QD) for gastrointestinal events in su...
    Medical condition: Treatment of osteoarthritis (OA) and/or rheumatoid arthritis (RA) in high GI risk patients
    Disease: Version SOC Term Classification Code Term Level
    8.0 10039073 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) BE (Completed) SE (Completed) CZ (Completed) LT (Completed) DE (Suspended by CA) EE (Completed) PT (Completed) GR (Completed) IE (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2008-001684-11 Sponsor Protocol Number: mentholmarch08 Start Date*: 2008-06-19
    Sponsor Name:University of Edinburgh
    Full Title: A Pilot Study into the Effect of Topical Menthol for Patients with Neuropathic-Type Pain.
    Medical condition: The condition under investigation is neuropathic-type pain. This may be due to a variety of causes including malignant neuropathic-type pain (such as tumour-related nerve compression or cancer-rel...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003888-19 Sponsor Protocol Number: OSU6162DB003 Start Date*: 2017-03-20
    Sponsor Name:A. Carlsson Research AB
    Full Title: Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of OSU6162 in the treatment of residual symptoms after stroke
    Medical condition: Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000557-35 Sponsor Protocol Number: NW-1029/001/II/2003 Start Date*: 2005-06-09
    Sponsor Name:Newron Pharmaceuticals SpA
    Full Title: A phase II, multi centre, pilot, randomised, ascending dose, double -blind, placebo controlled, dose titration study to determine the safety, maximum tolerated dose and preliminary evidence of effi...
    Medical condition: Neuropathic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-003233-34 Sponsor Protocol Number: 11048 Start Date*: 2012-01-19
    Sponsor Name:University of Nottingham
    Full Title: The effect of intravenous iron on postoperative transfusion requirements in hip fracture patients – a pilot study
    Medical condition: Anaemia following hip fracture
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022809-18 Sponsor Protocol Number: 2010-022809-18 Start Date*: 2010-11-26
    Sponsor Name:Hywel Dda Health Board
    Full Title: Effectiveness of Glucophage® SR as an adjunct to insulin in improving glycaemic control, without increasing the episodes of hypoglycaemia, in non-overweight patients with type-1 Diabetes.
    Medical condition: Type-1 Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005805-35 Sponsor Protocol Number: ARRAY-818-302 Start Date*: 2016-11-28
    Sponsor Name:Array BioPharma Inc.
    Full Title: A Multicenter, Randomized, Open-label, 3-Arm Phase 3 Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA) /Irino...
    Medical condition: BRAF V600E-mutant Metastatic Colorectal Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) HU (Completed) BE (Completed) AT (Completed) NL (Completed) CZ (Completed) DK (Completed) ES (Ongoing) NO (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004330-41 Sponsor Protocol Number: CH-GH/TOAST/0006 Start Date*: 2013-02-15
    Sponsor Name:University of Oxford
    Full Title: Do oral corticosteroids provide clinical and cost-effective symptom relief for sore throat? A multi-centre, double blind, randomized, placebo-controlled trial.
    Medical condition: Sore Throat
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10001093 Acute tonsillitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001171-23 Sponsor Protocol Number: ON/2016/6004 Start Date*: 2017-06-26
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: A multicentre randomised trial of First Line treatment pathways for newly diagnosed Immune Thrombocytopenia: Standard steroid treatment versus combined steroid and mycophenolate.
    Medical condition: Immune Thrombocytopenia
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-006207-36 Sponsor Protocol Number: 19122011 Start Date*: 2012-09-27
    Sponsor Name:Proreo Pharma Innovation AG
    Full Title: A multi centre, double blind, randomised, placebo controlled crossover study to evaluate the efficacy and tolerability of picotamide in the prophylaxis of migraine in patients presenting with migra...
    Medical condition: Migraine with aura, ICD-10NA G43.1
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-005355-16 Sponsor Protocol Number: WA20499 Start Date*: 2008-05-07
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study To Evaluate The Efficacy and Safety of Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus
    Medical condition: Systemic Lupus Erythematosus (SLE)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) FR (Completed) DE (Completed) ES (Completed) HU (Prematurely Ended) NL (Prematurely Ended) PT (Prematurely Ended) SE (Prematurely Ended) PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-002571-16 Sponsor Protocol Number: MBP8298-01 Amendment 04 Start Date*: 2007-06-29
    Sponsor Name:BioMS Technology Corp
    Full Title: A double-blind, placebo controlled multicentre study to evaluate the efficacy and safety of MBP8298 in subjects with secondary progressive multiple sclerosis.
    Medical condition: Secondary progressive multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10063400 Secondary progressive multiple sclerosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) FI (Completed) DK (Completed) ES (Completed) EE (Completed) NL (Completed) LT (Prematurely Ended) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003327-11 Sponsor Protocol Number: 3623 Start Date*: 2015-02-10
    Sponsor Name:University of Southampton
    Full Title: Alternative Treatments of Adult female Urinary Tract Infection: a double blind, placebo controlled,factorial randomised trial of Uva ursi and open pragmatic trial of ibuprofen.
    Medical condition: Acute urinary tract infections.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004862 10000698 Acute cystitis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002077-23 Sponsor Protocol Number: MeIn/03/Olm-Hyp/001 Start Date*: 2005-08-24
    Sponsor Name:MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
    Full Title: Efficacy and safety of Olmesartan medoxomil in elderly patients with mild to moderate hypertension
    Medical condition: Male or female outpatients, aged 65-89 years, with mild to moderate essential hypertension (sDBP>=90mmHg and sSBP>=140mmHg)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IE (Completed) AT (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-004858-33 Sponsor Protocol Number: Version 2.0 (03Nov2010) Start Date*: 2009-01-09
    Sponsor Name:University College London
    Full Title: Open label pilot study to treat women with chronic urinary retention or voiding dysfunction due to a primary disorder of sphincter relaxation (Fowler’s syndrome) with outpatient urethral sphincter ...
    Medical condition: Primary abnormality of the urethral sphincter or Fowlers Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046456 Urethral instrinsic sphincter deficiency LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002784-91 Sponsor Protocol Number: HAW0501 Start Date*: 2006-02-06
    Sponsor Name:Cardiff and Vale NHS Trust
    Full Title: A Randomized, Multicentre, Parallel Group Single-Blind Study to Assess the Efficacy and Safety of Dosing Mesalazine 800 mg Tablets (Asacol®) at 2.4 g Once Daily versus Divided Doses Three Times Dai...
    Medical condition: Ulcerative colitis is characterized by acute and chronic inflammatory changes to the mucosa and submucosa of the colon and rectum. Clinical presentations include increased stool frequency, bloody d...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-000118-31 Sponsor Protocol Number: CCTU0145 Start Date*: 2017-01-16
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: A randomised phase II double-blinded placebo-controlled trial of intravenous immunoglobulins and rituximab in patients with antibody-associated psychosis (SINAPPS2)
    Medical condition: Antibody associated Psychosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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