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Clinical trials for Nerve damage

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    80 result(s) found for: Nerve damage. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2009-016038-29 Sponsor Protocol Number: LIDO-2009 Start Date*: 2010-03-11
    Sponsor Name:Danish Pain Research Center
    Full Title: Topical lidocaine: Predictors of response in peripheral nerve damage
    Medical condition: Neuropathic pain due to Peripheral nerve damage
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011302 Peripheral nerve injuries HLT
    12.1 10034586 Peripheral nerve injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-005264-60 Sponsor Protocol Number: CHF6467-OPG Start Date*: 2021-11-26
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Safety and Efficacy of multiple doses of the PAINLESS Nerve Growth Factor CHF6467 in subjects with Optic Pathway Glioma (OPG). A randomized clinical trial (RCT)
    Medical condition: Optic pathway glioma - optic neuropathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10073338 Optic glioma PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-005802-29 Sponsor Protocol Number: RD/505/06 Start Date*: 2007-06-26
    Sponsor Name:Gwent Healthcare NHS Trust
    Full Title: Postoperative analgesia for Total knee replacement: A comparision between intrathecal morphine and peripheral nerve block.
    Medical condition: Postoperative analgesia for Total Knee Replacement
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10007521 Cardiac arrhythmias HLGT
    14.0 10022117 - Injury, poisoning and procedural complications 10029177 Nerve damage LLT
    14.0 10029205 - Nervous system disorders 10010914 Convulsions LLT
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10038678 Respiratory depression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-000299-25 Sponsor Protocol Number: 1.4 Start Date*: 2014-12-05
    Sponsor Name:Unfallkrankenhaus Salzburg
    Full Title: Dexmedetomidine for saphenous nerve blockade in patients undergoing anterior cruciate ligament replacement: a randomized, placebo-controlled, triple blinded study
    Medical condition: Dexmedetomidine -a selective alpha-2-receptor agonist- added to a local anaesthetic (ropivacaine) should prolong a saphenous block and the patients demand for the first analgesic. We designed a pro...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001855-10 Sponsor Protocol Number: SNAP1 Start Date*: 2019-01-22
    Sponsor Name:Department of Ophtalmology, Rigshospitalet-Glostrup
    Full Title: Steroids and Non-steroidal Anti-inflammatory drugs in the Postoperative regime after trabeculectomy. An investigator-initiated randomized study (The SNAP study)
    Medical condition: Medically uncontrolled glaucoma that requires filtration surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10018326 Glaucoma NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-003475-11 Sponsor Protocol Number: UCL/11/0083 Start Date*: 2011-11-15
    Sponsor Name:University College London (UCL)
    Full Title: A phase II double-blind, randomised, placebo-controlled trial of neuroprotection with phenytoin in acute optic neuritis
    Medical condition: Acute demyelinating optic neuritis
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10030942 Optic neuritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-004746-17 Sponsor Protocol Number: 17HH4283 Start Date*: 2018-03-05
    Sponsor Name:Joint Research Compliance Office, Imperial College London and Imperial College Healthcare NHS Trust
    Full Title: Pain relief with disease modification by Capsaicin 8% patch: a clinical study in Diabetic Peripheral Neuropathy
    Medical condition: Diabetic painful neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-004033-13 Sponsor Protocol Number: EMA401-005 Start Date*: 2012-02-06
    Sponsor Name:Spinifex Pharmaceuticals Pty Ltd
    Full Title: A Phase 2 open label biomarker study of angiotensin II type 2 receptor antagonist EMA401 for the treatment of pain in patients with chemotherapy-induced peripheral neuropathy.
    Medical condition: Chemotherapy induced peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004852 10040039 Sensory peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002846-21 Sponsor Protocol Number: PARENTIDE-02 Start Date*: 2017-04-10
    Sponsor Name:BCN Peptides S.A.
    Full Title: CLINICAL TRIAL PHASE IIa PROOF OF CONCEPT, DOUBLE BLIND, RANDOMIZED, PLACEBO-CONTROLLED IN PATIENTS WITH NEUROPATHIC PAIN DUE TO PERIPHERAL NERVE INJURY
    Medical condition: Patients with neuropathic pain due to peripheral nerve injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001058-85 Sponsor Protocol Number: WOE_2013_SB Start Date*: 2013-07-30
    Sponsor Name:Wörwag Pharma GmbH & Co. KG
    Full Title: EFFECTS OF BENFOTIAMINE ON INTRAEPIDERMAL NERVE FIBER DENSITY (IENFD) AND DIABETIC NEUROPATHY IN SUBJECTS WITH SENSORIMOTOR DIABETIC POLYNEUROPATHY: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, ...
    Medical condition: Diabetic neuropathy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10036113 Polyneuropathy in diabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002666-47 Sponsor Protocol Number: SOAP1 Start Date*: 2017-11-02
    Sponsor Name:Dpt. of Ophthalmology, Rigshospitalet-Glostrup
    Full Title: Effect of drop-less surgery compared to topical NSAID alone and combination of steroid and NSAID on central macular thickness after cataract surgery, a randomized controlled trial
    Medical condition: Postoperative cystoid macular edema following cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10070634 Irvine-Gass syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-001392-17 Sponsor Protocol Number: 19636 Start Date*: 2022-01-03
    Sponsor Name:Bayer AG
    Full Title: A randomized, double-blind, cross-over, placebo-controlled, multi-center, Phase 2a study to assess the safety and efficacy of BAY 2395840 in patients with diabetic neuropathic pain.
    Medical condition: Neuropathic pain associated with diabetic peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10067547 Diabetic peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) ES (Completed) SK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002436-82 Sponsor Protocol Number: EC11-441 Start Date*: 2012-12-13
    Sponsor Name:Isabel Pinilla Lozano
    Full Title: Melatonin effects on visual and sleep patterns anomalies in subjects diagnosed with Retinitis Pigmentosa
    Medical condition: To evaluate the sleep quality in patients with Retinitis Pigmentosa
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005484-32 Sponsor Protocol Number: VN-FT-01 Start Date*: 2015-05-28
    Sponsor Name:Lund University
    Full Title: Double-blind, randomized placebo controlled study on the effect from cortisone treatment of vestibular neuritis - function, subjective well-being and stress
    Medical condition: Acute vestibular syndrome better known as Vestibular neuritis
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004863 10047392 Vestibular nerve damage LLT
    17.1 100000004854 10047388 Vestibular function disorder LLT
    17.1 100000004862 10051781 Vestibular paralysis LLT
    17.1 100000004854 10013285 Disorder vestibular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001949-42 Sponsor Protocol Number: BRD50 Start Date*: 2005-09-08
    Sponsor Name:University College London
    Full Title: A randomised controlled trial of neuroprotection with lamotrigine in secondary progressive multiple sclerosis
    Medical condition: Multiple sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-003079-31 Sponsor Protocol Number: QRK207 Start Date*: 2016-10-20
    Sponsor Name:Quark Pharmaceuticals Inc.
    Full Title: A PHASE 2/3, RANDOMIZED, DOUBLE-MASKED, SHAMCONTROLLED TRIAL OF QPI-1007 DELIVERED BY SINGLE OR MULTI-DOSE INTRAVITREAL INJECTION(S) TO SUBJECTS WITH ACUTE NONARTERITIC ANTERIOR ISCHEMIC OPTIC NEU...
    Medical condition: NAION typically presents as an abrupt, painless monocular vision loss. Visual loss varies widely, ranging from visual field loss only to complete blindness. The neuronal degeneration process in N...
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004853 10068242 Nonarteritic anterior ischaemic optic neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022025-15 Sponsor Protocol Number: 10-2-055 Start Date*: 2011-02-21
    Sponsor Name:MUMC
    Full Title: Intradiscal Methylene Blue Injection Treatment for Chronic Discogenic Low back pain A prospective Clinical Series followed by a Randomised Placebo-Controlled Clinical Trial
    Medical condition: The Randomized Clinical Trial (RCT) aims to prove the hypothesis that Intradiscal Methylene blue Injection is capable of better pain reduction than the best available treatment in patients sufferin...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001572-42 Sponsor Protocol Number: FCN-159-002 Start Date*: 2021-12-21
    Sponsor Name:Shanghai Fosun Pharmaceutical Industrial Development Co.,Ltd.
    Full Title: A multi-center, open-label, single-arm Phase I dose-escalation and Phase II dose-expansion study to evaluate the safety, tolerability, PK characteristics and anti-tumor activity of FCN-159 in adult...
    Medical condition: Participants diagnosed with Neurofibromatosis NF1-related plexiform neurofibromas (PN) and symptomatic with requirement of systematic therapy per investigator’s judgment. A PN is defined as a neuro...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10029270 Neurofibromatosis, type 1 (von Recklinghausen's disease) LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) IT (Ongoing) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004544-10 Sponsor Protocol Number: AUT-001 Start Date*: 2017-09-18
    Sponsor Name:Audion Therapeutics BV
    Full Title: A phase I/II multiple ascending dose open-label safety and efficacy study of the Notch Inhibitor LY3056480 in patients with mild to moderate sensorineural hearing loss.
    Medical condition: Sensorineural hearing loss (SNHL)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004854 10040016 Sensorineural hearing loss LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) GR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003278-10 Sponsor Protocol Number: 192024-056 Start Date*: Information not available in EudraCT
    Sponsor Name:Allergan Ltd.
    Full Title: A Multicenter, Double-masked, Randomized, Active-controlled, Parallel Study of the Safety and Efficacy of Once-daily Bimatoprost Preservative-free Ophthalmic Solution Compared to Twice-daily Timolo...
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10018304 Glaucoma PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing) GB (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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