Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Normal sinus rhythm

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    50 result(s) found for: Normal sinus rhythm. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2009-011291-29 Sponsor Protocol Number: RACE 3 Start Date*: 2011-08-16
    Sponsor Name:Interuniversity Cardiology Institute of the Netherlands (ICIN)
    Full Title: Routine versus Aggressive Upstream Rhythm Control for Prevention of Early Atrial Fibrillation in Heart Failure: RACE 3
    Medical condition: atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10003661 Atrial fibrillation paroxysmal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001529-18 Sponsor Protocol Number: LGN-VN-003 Start Date*: 2015-08-18
    Sponsor Name:Laguna Pharmaceuticals, Inc.
    Full Title: RESTORE SR: A multi-center, Randomized, double-blind, placebo-controlled study to Evaluate the Safety and efficacy of a single oral dose of vanoxerine for The conversion Of subjects with REcent ons...
    Medical condition: Recent atrial fibrillation (AF) or atrial flutter (AFL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) NL (Ongoing) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-002516-33 Sponsor Protocol Number: NCT01420393 Start Date*: 2015-09-03
    Sponsor Name:University of Ottawa Heart Institute
    Full Title: A Randomized Ablation-based atrial Fibrillation rhythm control versus rate control Trial in patients with heart failure and high burden Atrial Fibrillation
    Medical condition: The study is comparing two accepted treatment methods (rhythm control-Catheter ablation with or without anti-arrhythmic drug control of maintaining sinus rhythm versus rate controls with medical th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000346-21 Sponsor Protocol Number: S219.3.118 Start Date*: 2004-11-05
    Sponsor Name:Solvay Pharmaceuticals GmbH
    Full Title: Controlled, Parallel Design Study to Evaluate the Efficacy and Safety of Intravenous Tedisamil Sesquifumarate in the Rapid Conversion to Normal Sinus Rhythm in Female Subjects with Recent Onset Atr...
    Medical condition: Recent Onset Atrial Fibrillation or Flutter
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed) ES (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002262-37 Sponsor Protocol Number: ATP1 Start Date*: 2004-10-27
    Sponsor Name:Newcastle Hospitals Trust
    Full Title: Adenosine testing in the diagnosis of unexplained syncope: A pilot study
    Medical condition: Syncope
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001129-17 Sponsor Protocol Number: LDLL300.301 Start Date*: 2017-06-19
    Sponsor Name:AOP Orphan Pharmaceuticals GmbH
    Full Title: A multicenter, open-label study to investigate the effectiveness and safety of AOP Landiolol in controlling supraventricular tachycardia in pediatric patients (LANDI-PED).
    Medical condition: Supraventricular tachycardia in pediatric patients.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10074640 Junctional ectopic tachycardia PT
    20.0 10007541 - Cardiac disorders 10042604 Supraventricular tachycardia PT
    20.0 10007541 - Cardiac disorders 10003662 Atrial flutter PT
    20.0 10007541 - Cardiac disorders 10040752 Sinus tachycardia PT
    20.0 10007541 - Cardiac disorders 10003668 Atrial tachycardia PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed) DE (Ongoing) LT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2012-001260-29 Sponsor Protocol Number: 2012-CARDAF Start Date*: 2012-04-24
    Sponsor Name:FONDAZIONE ISTITUTO SAN RAFFAELE-G.GIGLIO
    Full Title: Identification of predictive plasma Biomarkers and use of a high dosage statin during a procedure of Parrossistic Atrial Fibrillation pharmacological Cardioversion
    Medical condition: Parossistic Atrial Fibrillation according to the European Socierty of Cardiology (ESC)criteria
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006614-37 Sponsor Protocol Number: CryoStopPersAF Start Date*: 2022-05-11
    Sponsor Name:Region Örebro
    Full Title: First-line cryoablation for early treatment of Persistent Atrial Fibrillation – a randomized study comparing early trigger isolation using the Cryoballoon versus antiarrhythmic medication.
    Medical condition: Persistent symptomatic atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    25.1 100000004865 10081865 Cardiac catheter ablation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-000204-33 Sponsor Protocol Number: 01 Start Date*: 2006-12-29
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE DI CIRCOLO A.O. DI RILIEVO REGIONALE
    Full Title: REPEATED I.V. BOLUSES FLECAINIDE FOR ACUTE ATRIAL FIBRILLATION TERMINATION A SINGLE BLIND RANDOMIZED REGIMEN CONTROLLED TRIAL.
    Medical condition: ATRIAL FIBRILLATION
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001430-18 Sponsor Protocol Number: 5101127 Start Date*: 2019-08-12
    Sponsor Name:Kuopio University Hospital
    Full Title: Does postoperative intravenous corticosteroid and intravenous beta blocker management prevent atrial fibrillation after cardiac surgery?
    Medical condition: new onset atrial fibrillation and paroxysmal atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000984-81 Sponsor Protocol Number: 04-7-010 Start Date*: 2004-09-09
    Sponsor Name:Astellas Pharma US, Inc.
    Full Title: A PHASE III PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER, TOLERANCE AND EFFICACY STUDY OF RSD1235 IN SUBJECTS WITH ATRIAL FIBRILLATION OR ATRIAL FLUTTER
    Medical condition: Arrhythmias are abnormal rhythms of the heart. The term arrhythmia refers to a deviation from the normal sequence of initiation and conduction of electrical impulses, which cause the heart to beat....
    Disease: Version SOC Term Classification Code Term Level
    61 10003658 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-004195-20 Sponsor Protocol Number: 05-7-012 Start Date*: 2005-12-12
    Sponsor Name:Astellas Pharma US, Inc.
    Full Title: A Phase 3, Multi-Center, Open Label Safety Study of RSD1235 in Subjects with Atrial Fibrillation.
    Medical condition: Arrhythmias are abnormal rhythms of the heart. The term arrhythmia refers to a deviation from the normal sequence of initiation and conduction of electrical impulses, which cause the heart to beat...
    Disease: Version SOC Term Classification Code Term Level
    61 10003658 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-001627-40 Sponsor Protocol Number: FLE-007 Start Date*: 2022-06-07
    Sponsor Name:InCarda Therapeutics, Inc.
    Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation to Sinus Rhythm
    Medical condition: Recent-onset symptomatic atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) ES (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-004327-17 Sponsor Protocol Number: CHSY244X2201 Start Date*: 2021-04-14
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, investigator- and participant-blinded study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of HSY244 in participants with atrial fibrillation
    Medical condition: Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005743-14 Sponsor Protocol Number: 15.0214 Start Date*: 2016-04-15
    Sponsor Name:St Georges University Hospital NHS Foundation Trust
    Full Title: Fetal Atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial
    Medical condition: Fetal atrial flutter without hydrops, supraventricular tachycardia without hydrops and supraventricular tachycardia with hydrops
    Disease:
    Population Age: In utero, Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-001871-39 Sponsor Protocol Number: CY 1121 Start Date*: 2007-01-02
    Sponsor Name:Cytokinetics, Inc
    Full Title: A PHASE II, MULTI CENTRE, DOUBLE-BLIND, RANDOMISED, PLACEBO CONTROLLED, DOSE-ESCALATION, PHARMACOKINETIC AND PHARMACODYNAMIC STUDY OF CK-1827452 IN PATIENTS WITH STABLE HEART FAILURE.
    Medical condition: The drug is being developed for heart failure. This is the first study in patients with stable heart failure .
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014643-36 Sponsor Protocol Number: MeBe/08/NEB-MICR/001 Start Date*: 2010-04-23
    Sponsor Name:MENARINI Benelux NV/SA
    Full Title: Effects Of The Administration Of Nebivolol Versus Carvedilol On Microcirculatory Endothelial Function, Arterial Stiffness And Wave Reflection In Healthy Volunteers” (NeCaMic-study)
    Medical condition: Microcirculatory Endothelial Function, Arterial Stiffness And Wave Reflection
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013228-21 Sponsor Protocol Number: Start Date*: 2010-07-06
    Sponsor Name:University of Oxford
    Full Title: Prevention of atrial oxidative stress and electrical remodelling in patients undergoing cardiac surgery: randomised placebo-controlled trial of perioperative high-dose atorvastatin
    Medical condition: POST-OPERATIVE ATRIAL FIBRILLATION
    Disease: Version SOC Term Classification Code Term Level
    13 10003658 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-001626-26 Sponsor Protocol Number: OMT28-C0201 Start Date*: 2019-01-23
    Sponsor Name:OMEICOS Therapeutics GmbH
    Full Title: A Placebo-controlled, double-blind, Randomized, dose finding phase II study on OMT-28 in MaIntenance of Sinus rhythm after Electrical cardioversion in patients with persistent Atrial Fibrillation (...
    Medical condition: Persistent atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BG (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-018374-20 Sponsor Protocol Number: 6517-CL-0020 Start Date*: 2010-12-09
    Sponsor Name:Cardiome UK Limited
    Full Title: A Phase 3b Randomized, Double-Blind, Placebo Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of Vernakalant Hydrochloride Injection in Patients with Recent Onset Symptomatic At...
    Medical condition: Recent Onset Symptomatic Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Mon May 12 03:51:49 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA