- Trials with a EudraCT protocol (107)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
107 result(s) found for: RNA activation.
Displaying page 1 of 6.
EudraCT Number: 2014-004015-36 | Sponsor Protocol Number: IN-IT-236-1320 | Start Date*: 2015-02-16 |
Sponsor Name:AZIENDA OSPEDALIERA SAN PAOLO | ||
Full Title: Role of a switch strategy to elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate (QUAD) on HIV reservoir and immune activation. | ||
Medical condition: Human Immunodeficiency Virus (HIV-1) Infection | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: IT (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2015-004427-31 | Sponsor Protocol Number: TAFCNS2015 | Start Date*: 2016-03-07 |
Sponsor Name:Gothenburg University | ||
Full Title: Tenofovir Alafenamide Fumarate (TAF) effect on residual intrathecal immune activation | ||
Medical condition: HIV-infection in the central nervous system | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: SE (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2009-015113-44 | Sponsor Protocol Number: NEAT001 | Start Date*: 2010-05-19 | |||||||||||
Sponsor Name:ANSR | |||||||||||||
Full Title: Ensayo abierto, aleatorizado, de dos años de duración, en el que se comparan dos regímenes de primera línea en sujetos infectados por el VIH que no han recibido tratamiento antirretroviral previo: ... | |||||||||||||
Medical condition: Infección por el virus de la inmunodeficiencia humana | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Completed) FR (Completed) SE (Completed) IE (Completed) DK (Completed) PT (Completed) AT (Completed) DE (Completed) GB (Completed) PL (Completed) IT (Completed) BE (Completed) NL (Completed) HU (Completed) GR (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2023-000061-14 | Sponsor Protocol Number: BCN04-DASA | Start Date*: 2023-05-26 | |||||||||||
Sponsor Name:Institut de Recerca Germans Trias i Pujol | |||||||||||||
Full Title: Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People with HIV under Antiretroviral Treatment | |||||||||||||
Medical condition: Human immunodeficiency virus (HIV) | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-005634-59 | Sponsor Protocol Number: TEA-001 | Start Date*: 2015-04-29 | |||||||||||
Sponsor Name:Aarhus University Hospital | |||||||||||||
Full Title: Toll-like receptor 9 enhancement of antiviral immunity in chronic HIV-1 infection: a phase 1b/2a trial (TEACH) | |||||||||||||
Medical condition: HIV | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-000800-14 | Sponsor Protocol Number: FIS-TAR-01-2019 | Start Date*: 2020-02-07 | ||||||||||||||||
Sponsor Name:Fundación Pública Andaluza para la Gestión en Salud de Sevilla (FISEVI) | ||||||||||||||||||
Full Title: Effectiveness of a dual therapy based on dolutegravir plus lamivudine on reduction of the viral reservoir, immune recovery and immune activation compared with a triple antiretroviral therapy based ... | ||||||||||||||||||
Medical condition: Adult patients with HIV infection without previous treatment | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: ES (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-023625-38 | Sponsor Protocol Number: JF003 | Start Date*: 2012-11-13 | |||||||||||
Sponsor Name:Guy's and St Thomas' NHS Foundation Trust | |||||||||||||
Full Title: Investigating the effect of Maraviroc on microbial translocation in HIV-1 infected individuals who are receiving antiretroviral therapy | |||||||||||||
Medical condition: HIV | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-003215-66 | Sponsor Protocol Number: MARAVITRANS | Start Date*: 2012-09-26 |
Sponsor Name:FIBio Hospital Universitario Ramón y Cajal | ||
Full Title: EFFECT OF MARAVIROC ON THE TRANSCRIPTION OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) IN RESTING CD4+ T LYMPHOCYTES IN PATIENTS ON ANTIRETROVIRAL TREATMENT WITH SUPPRESSED VIRAL LOAD | ||
Medical condition: HIV-infected patients | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: ES (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2014-005611-16 | Sponsor Protocol Number: 52003 | Start Date*: 2015-03-16 | |||||||||||
Sponsor Name:Academic Medical Center, University of Amsterdam | |||||||||||||
Full Title: Effect of Intravenous Administration of C1-inhibitor on Inflammation and Coagulation after Bronchial Instillation of House Dust Mite Allergen and Lipopolysaccharide in Allergic Asthma Patients | |||||||||||||
Medical condition: Mild asthmatics with house dust mite allergy | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-005473-35 | Sponsor Protocol Number: DISCOR-RAL | Start Date*: 2008-11-12 | |||||||||||
Sponsor Name:Fundació Lluita contra la SIDA | |||||||||||||
Full Title: PILOT STUDY TO ASSESS THE ROLE OF IMMUNE ACTIVATION AND APOPTOSIS AS A MARKER FOR TREATMENT INTENSIFICATION WITH RALTEGRAVIR IN HIV-INFECTED PATIENTS ON ANTIRETROVIRAL THERAPY WITH LONG-TERM VIRAL ... | |||||||||||||
Medical condition: Infección VIH-1 | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-002006-39 | Sponsor Protocol Number: ESTER | Start Date*: 2016-11-14 | |||||||||||
Sponsor Name:ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE "LAZZARO SPALLANZANI" | |||||||||||||
Full Title: Study on Efficacy and safety of an early proactive Switch To ElvitegraviR/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) in patients with a primary HIV-1 infection | |||||||||||||
Medical condition: Treatment of HIV infection | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-003142-27 | Sponsor Protocol Number: RALAM | Start Date*: 2015-07-13 |
Sponsor Name:Fundació Clinic per a la Recerca Biomédica | ||
Full Title: A pilot 24-week open-label, randomized, controlled clinical trial to assess the safety, tolerability and efficacy of dual therapy with Raltegravir/Lamivudine combination when replacing standard com... | ||
Medical condition: Chronic HIV infection | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: ES (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2017-000985-31 | Sponsor Protocol Number: RALAM-II | Start Date*: 2017-10-04 | |||||||||||
Sponsor Name:Fundació Clinic per a la Recerca Biomédica | |||||||||||||
Full Title: Phase 3b, single arm, single site simplification study with dual therapy including 3TC (300 mg QD) plus Raltegravir (1200 mg QD) in virologically suppressed HIV-1 infected atients experiencing inco... | |||||||||||||
Medical condition: Virologically suppressed Human Immunodeficiency Virus-1 infected patients experiencing inconvenience, toxicity, negative impact on comorbidities or risk of drug-drug interactions with their current... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-002733-10 | Sponsor Protocol Number: Dual-Triple-ART | Start Date*: 2019-08-13 | |||||||||||
Sponsor Name:FUNDACIÓ LLUITA CONTRA LA SIDA | |||||||||||||
Full Title: Exploratory, open-label, randomized clinical trial to assess the efficacy of first-line dual vs. triple antiretroviral therapy (art) in hiv-1 reservoir and in peripheral compartments in hiv-infecte... | |||||||||||||
Medical condition: HIV infection | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2015-003186-28 | Sponsor Protocol Number: BPC01_002 | Start Date*: 2016-01-13 | |||||||||||
Sponsor Name:Bionor Pharma ASA | |||||||||||||
Full Title: BIOSKILL: Studying Vacc-4x, an HIV therapeutic vaccine, an assessment of immune-mediated anti-viral effects, when administered with adjuvant GM-CSF prior to HIV latent reservoir activation by the H... | |||||||||||||
Medical condition: HIV infection | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-002107-15 | Sponsor Protocol Number: Kirby-MARCH | Start Date*: 2011-12-16 | |||||||||||
Sponsor Name:Kirby Institute, University of New South Wa | |||||||||||||
Full Title: Maraviroc Switch collaborative study A randomised, open-label study to evaluate the efficacy and safety of maraviroc (MVC) as a switch for either nucleoside or nucleotide analogue reverse transcr... | |||||||||||||
Medical condition: Chronic HIV-1 infection | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Completed) GB (Completed) DE (Completed) ES (Completed) PL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-004241-32 | Sponsor Protocol Number: EDOLAS | Start Date*: 2020-02-07 | |||||||||||
Sponsor Name:SOCIETA' ITALIANA MALATTIE INFETTIVE E TROPICALI | |||||||||||||
Full Title: Efficacy and safety of early switching to dolutegravir/lamivudine (DTG/3TC) from INSTI-based three-drug regimens in HIV-1-infected adults previously naïve who achieve virological suppression | |||||||||||||
Medical condition: HIV-1 infected individuals currently taking an INSTI-based three-drug first-line regimen for less than 18 months and who have been virologically suppressed with HIV-1 RNA <50 copies/mL | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-022293-14 | Sponsor Protocol Number: ANRS146OPTIMAL | Start Date*: 2012-08-22 |
Sponsor Name:Inserm-ANRS | ||
Full Title: Optimized Phase III Trial of Immuno-stimulation with Maraviroc, a CCR5 antagonist, combined with Anti Retroviral Therapy (cART) in advanced, Late diagnosed HIV-1 infected patients with an AIDS-defi... | ||
Medical condition: HIV infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: ES (Completed) IT (Completed) | ||
Trial results: View results |
EudraCT Number: 2016-002722-36 | Sponsor Protocol Number: RAGTIME | Start Date*: 2017-03-29 | |||||||||||
Sponsor Name:FUNDACIÓ LLUITA CONTRA LA SIDA | |||||||||||||
Full Title: Randomized, double-blind, placebo-controlled clinical trial to evaluate the effect of Raltegravir intensification (1.200 mg QD) on the gut microbiota of chronically HIV-1 infected subject over time... | |||||||||||||
Medical condition: HIV-1 | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-005636-26 | Sponsor Protocol Number: HCV12-01 | Start Date*: 2012-04-13 |
Sponsor Name:Foundation for Liver Research | ||
Full Title: Effect of Telaprevir in triple therapy for chronic hepatitis C patients on Intrahepatic immunological Mechanisms | ||
Medical condition: Chronic hepatitis C | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: NL (Ongoing) | ||
Trial results: (No results available) |
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