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Clinical trials for Scars

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    73 result(s) found for: Scars. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2022-000842-14 Sponsor Protocol Number: TBCH2022 Start Date*: 2022-07-01
    Sponsor Name:Dra.Margarita Ramirez&Dra.Ifara Sánchez
    Full Title: Trial study to evaluate the effectiveness of botulinum toxin A (incobotulinumtoxin) injection in reducing the pain and size of painful scars (including hypertrophic and keloid scars)
    Medical condition: painful scars
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002124-28 Sponsor Protocol Number: RN1001-0091 Start Date*: 2008-11-17
    Sponsor Name:Renovo Ltd
    Full Title: A double blind, within patient, placebo controlled trial to assess the efficacy of Juvista (avotermin) in conjunction with scar revision surgery for the improvement of disfiguring scars.
    Medical condition: Improvement of scar appearance
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039589 Scarring LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) HU (Completed) ES (Completed) DK (Completed) IT (Completed) DE (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004110-10 Sponsor Protocol Number: 2ABC Start Date*: 2017-12-21
    Sponsor Name:Medical University of Warsaw
    Full Title: Evaluation the safety and efficacy of the treatment of scars and cutis laxa syndrome with the use of autologous (fresh and stored) stem cells isolated from adipose tissue within the project: 'The t...
    Medical condition: Scar or cutis laxa
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10039581 Scar conditions and fibrosis of skin LLT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10011692 Cutis laxa PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2011-000626-29 Sponsor Protocol Number: KS001 Start Date*: 2011-12-13
    Sponsor Name:QUEEN MARY UNIVERSITY OF LONDON
    Full Title: Keloid Scars: A randomised clinical and laboratory based study on the treatment and differentiation factors of the local disease
    Medical condition: Keloid scarring
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-003889-42 Sponsor Protocol Number: RN1001-319-1009 Start Date*: 2008-08-26
    Sponsor Name:Renovo
    Full Title: A double blind, placebo controlled, randomised trial to investigate the efficacy of Juvista in the prevention or improvement of scar appearance when administered intradermally to approximated wound...
    Medical condition: Patients undergoing scar revision surgery are left with scarring, which can vary from fine flat asymptomatic scars to hypertrophic scars. Studies show that these visible marks can cause emotional d...
    Disease: Version SOC Term Classification Code Term Level
    6.1 10039583 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004355-37 Sponsor Protocol Number: B5301001 Start Date*: 2013-06-04
    Sponsor Name:Pfizer Inc.
    Full Title: A PHASE 2, RANDOMIZED, DOUBLE-BLIND, WITHIN-SUBJECT, PLACEBO CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-06473871 IN REDUCING HYPERTROPHIC SKIN SCARRING
    Medical condition: Hypertrophic skin scarring
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) ES (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-004938-24 Sponsor Protocol Number: RN1001-0098 Start Date*: 2009-03-24
    Sponsor Name:Renovo
    Full Title: A within patient, placebo controlled, proof of concept trial to assess the efficacy of Juvista in improving the appearance of existing scars that are 2-6 months old.
    Medical condition: Improvement of existing scars
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039589 Scarring LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-001988-12 Sponsor Protocol Number: 1.2000 Start Date*: 2015-02-02
    Sponsor Name:Academic Medical Center, Amsterdam
    Full Title: Fractional CO2 laser assisted delivery of topical articaine and epinephrine solution vs. topical EMLA administration: a randomized controlled pilot study
    Medical condition: local anesthesia of the skin prior to laser therapy of acne and traumatic scars
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003216-37 Sponsor Protocol Number: n.a. Start Date*: 2015-02-12
    Sponsor Name:
    Full Title: Efficacy of Verapamil/ Verapamil-Kenacort injection versus Kenacort injection in Scar Treatment
    Medical condition: Hypertrophic and keloid scars are pathological scars as a result of dermal injury and exhibit exuberant, indefinite growth of collagen during wound healing. Hypertrophic and keloid scars often caus...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001066-15 Sponsor Protocol Number: LR19912019 Start Date*: 2019-08-16
    Sponsor Name:Merete Hædersdal
    Full Title: Treatment of hypertrophic scars using needle-free jet-injection of triamcinolone and 5-Fluorouracile: a prospective, controlled, randomized, single-blinded split-lesion trial.
    Medical condition: Hypertrophic scars on 20 participants
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10070845 Skin scarring LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-015163-14 Sponsor Protocol Number: 73191198 Start Date*: 2010-01-08
    Sponsor Name:Department of Pediatrics Aarhus University Hospital Skejby
    Full Title: Reduction of hypertrophic scars and keloid by use of corticosteroid cream after removal of a tunneled central venous catheter in childhood cancer survivors
    Medical condition: Development of hypertrophic and keloid scars after removal of tunneled central venous catheters in childhood cancer survivors
    Disease: Version SOC Term Classification Code Term Level
    12.0 10020879 Hypertrophic scar LLT
    12.0 10023330 Keloid scar LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001362-32 Sponsor Protocol Number: Prot-06032007 Start Date*: 2008-03-03
    Sponsor Name:University Hospitals Of Leicester NHS Trust
    Full Title: The use of non-ionic contrast media to clear corneal scars
    Medical condition: Will plan to investigate patients who would benefit from cataract surgery but whom have corneal scarring which would make surgery difficult.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011044 Corneal scar LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-006050-51 Sponsor Protocol Number: RD.06.SPR.202395 Start Date*: 2021-08-03
    Sponsor Name:Galderma S.A.
    Full Title: Evaluation of the risk of atrophic acne scar formation during treatment of acne vulgaris subjects with trifarotene 50 µg/g cream versus vehicle cream over 24 weeks
    Medical condition: acne vulgaris
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10000519 Acne vulgaris LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-013455-30 Sponsor Protocol Number: AOBS-ECT-CH Start Date*: 2009-12-15
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: EFFICACY OF ELETTROPORATION COMBINED WITH BLEOMYCIN IN THE TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS: A PILOT STUDY
    Medical condition: KELOIDS AND HYPERTROPHIC SCARS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040785 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017400-91 Sponsor Protocol Number: RN1003-0110 Start Date*: 2010-04-09
    Sponsor Name:Renovo
    Full Title: An exploratory, single centre, randomized, placebo controlled, assessor blind clinical trial to assess the effects of intradermal administrations of Prevascar on scarring in human subjects of Afric...
    Medical condition: Improvement of scarring in subjects of African Continental Group ancestry
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001455-11 Sponsor Protocol Number: RN1003-0027 Start Date*: 2006-04-03
    Sponsor Name:Renovo Ltd
    Full Title: A single centre, placebo and standard care controlled, double blind, randomised, trial to investigate the efficacy of eight doses of RN1003 in the reduction of scarring from approximated wound marg...
    Medical condition: Prevention and reduction of scarring
    Disease: Version SOC Term Classification Code Term Level
    6.1 10039580 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000388-10 Sponsor Protocol Number: RF-2010-2318192 Start Date*: 2013-03-30
    Sponsor Name:AZIENDA ULSS N.9 - TREVISO, UOC PEDIATRIA
    Full Title: Oral steroids for reducing renal scarring in infants with febrile urinary tract infections at high risk for renal scar development: a randomized controlled trial
    Medical condition: Infants with febrile UTI at higher risk for renal scar development based on PCT values ≥ 1 ng/mL
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-004496-12 Sponsor Protocol Number: BR-ICG-IV-NACT Start Date*: 2013-12-05
    Sponsor Name:Institut Jules Bordet
    Full Title: Study of the (intravenously injected) ICG distribution in tumour bearing breasts and in axillary pieces of dissection of patients who have received neo-adjuvant therapy for histologically proven ma...
    Medical condition: imaging of tumours and their margins after intravenous injection of Indocyanine Green to breast cancer patients
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002462-41 Sponsor Protocol Number: TBRU-dS-RAC-PII Start Date*: 2018-10-29
    Sponsor Name:CUTISS AG
    Full Title: A Phase II, prospective, intra-patient randomized controlled, multicentre study to evaluate the safety and efficacy of an autologous bio-engineered dermo-epidermal skin substitute (EHSG-KF) for the...
    Medical condition: Adults and children with full thickness skin defects
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-001672-55 Sponsor Protocol Number: MW2010-03-02 Start Date*: 2014-09-22
    Sponsor Name:MediWound Ltd.
    Full Title: A multicenter, multinational, randomized, controlled, assessor blinded study, performed in subjects with thermal burns, to evaluate the efficacy and safety of NexoBrid compared to Gel Vehicle and c...
    Medical condition: The study objective is to evaluate the efficacy and safety of NexoBrid in removing burn eschar in hospitalized subjects with thermal burns.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10043418 Thermal burns HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) RO (Completed) LV (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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