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Clinical trials for Sperm

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,708 result(s) found for: Sperm. Displaying page 1 of 86.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-017940-15 Sponsor Protocol Number: P081227 Start Date*: 2010-04-20
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Devenir de la spermatogénèse chez les hommes drépanocytaires traités médicalement (HYDREP).
    Medical condition: Drépanocytose
    Disease: Version SOC Term Classification Code Term Level
    8.1 10041479 drépanocytose PT
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003451-42 Sponsor Protocol Number: 19642021 Start Date*: 2021-12-23
    Sponsor Name:Dept. of Growth and Reproduction
    Full Title: FITMI - First In Treating Male Infertility
    Medical condition: Male infertility
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038604 - Reproductive system and breast disorders 10021929 Infertility male PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002859-16 Sponsor Protocol Number: BXL628 02 17 Start Date*: 2007-10-10
    Sponsor Name:BIOXELL SPA
    Full Title: A randomized, double blind, placebo controlled, parallel group study to determine the effect of Elocalcitol on sperm parameters in infertile male patients
    Medical condition: male infertility
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021929 Infertility male LLT
    Population Age: Adults Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000402-38 Sponsor Protocol Number: GS-US-418-4279 Start Date*: 2018-01-19
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Testicular Safety of Filgotinib in Adult Males with Moderately to Severely Active Inflammatory Bowel Disease
    Medical condition: To evaluate the testicular safety of filgotinib in adult males with moderately to severely Active Inflammatory Bowel Disease
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    20.0 100000004856 10013099 Disease Crohns LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) AT (Completed) PT (Prematurely Ended) NL (Prematurely Ended) SE (Prematurely Ended) BE (Prematurely Ended) ES (Prematurely Ended) RO (Completed)
    Trial results: View results
    EudraCT Number: 2019-000315-91 Sponsor Protocol Number: RG_18-236 Start Date*: 2019-09-09
    Sponsor Name:University of Birmingham
    Full Title: The pAToMiUM Trial: pilot trial of Antioxidant Therapy of Men in Unexplained Miscarriage
    Medical condition: Unexplained miscarriage and how this may relate to the quality of the sperm DNA at conception, with particular emphasis on chromatin structure and DNA fragmentation and whether this may be improved...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10065877 Dietary and nutritional therapies HLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-003933-14 Sponsor Protocol Number: GLPG0634-CL-227 Start Date*: 2019-05-27
    Sponsor Name:Galapagos NV
    Full Title: A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Effect of Filgotinib on Semen Parameters in Adult Males with active Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosin...
    Medical condition: Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10002556 Ankylosing spondylitis PT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10037160 Psoriatic arthritis LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10076297 Non-radiographic axial spondyloarthritis LLT
    Population Age: Adults Gender: Male
    Trial protocol: LV (Completed) EE (Completed) BG (Completed) BE (Completed) CZ (Completed) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-000655-24 Sponsor Protocol Number: CBG-study2 Start Date*: 2015-04-28
    Sponsor Name:rigshospitalet
    Full Title: Denosumab and male infertility: a prospective intervention study
    Medical condition: Male infertility especially low sperm count
    Disease: Version SOC Term Classification Code Term Level
    18.0 10038604 - Reproductive system and breast disorders 10021929 Infertility male PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-000722-19 Sponsor Protocol Number: M12-919 Start Date*: 2016-10-24
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Single-Arm Study of the Effects of Atrasentan on Spermatogenesis and Testicular Function
    Medical condition: Diabetic Nephropathy
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038359 - Renal and urinary disorders 10061835 Diabetic nephropathy PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-020196-23 Sponsor Protocol Number: EMR 700623-521 Start Date*: 2011-04-14
    Sponsor Name:MERCK SERONO SPA
    Full Title: A phase II, multicentre, open label, prospective, interventional study to evaluate the sperm DNA fragmentation in idiopathic male infertility before and after treatment with Gonal-f PEN 900 IU.
    Medical condition: Idiophatic male infertility
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014698 SOC
    Population Age: Adults Gender: Male
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005315-26 Sponsor Protocol Number: A25165 Start Date*: 2008-07-01
    Sponsor Name:CONRAD, Eastern Virgina Medical School
    Full Title: Sperm Suppression and Contraceptive Protection provived by Norethisterone Enantate (NET-EN) combined with Testosterone Undecanoate (TU) in healthy men.
    Medical condition: The proposed study is designed to evaluate whether the combination of a progestin, norethisterone enantate (NET-EN), and an androgen, testosterone undecanoate (TU), represents a safe and effective ...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10065589 Male contraception PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) IT (Temporarily Halted) GB (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2012-001258-25 Sponsor Protocol Number: MK8962-031-00 Start Date*: 2012-11-29
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A phase III, multi-center, open label, uncontrolled trial to investigate the efficacy and safety of MK-8962 (corifollitropin alfa) in combination with human Chorionic Gonadotropin (hCG) in inducing...
    Medical condition: Hypogonadotropic hypogonadism (HH) in males may result from either absent or inadequate gonadotropin-releasing hormone (GnRH) secretion by the hypothalamus or failure of pituitary gonadotropin secr...
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004860 10021012 Hypogonadotrophic hypogonadism LLT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed) ES (Completed) IT (Completed) GB (Completed) PL (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-006105-40 Sponsor Protocol Number: COQ10INF Start Date*: 2006-06-05
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI
    Full Title: TREATMENT OF IDIOPATHIC ASTHENOZOOSPERMIE WITH COENZYME Q10. A DOUBLE BLIND CONTROLLED STUDY
    Medical condition: IDIOPATHIC ASTHENOZOOSPERMIA
    Disease: Version SOC Term Classification Code Term Level
    6.1 10013358 HLT
    Population Age: Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002521-19 Sponsor Protocol Number: FSH_IMEN Start Date*: 2015-10-19
    Sponsor Name:Instituto de Investigación Sanitaria La Fe
    Full Title: "Pilot study on the effect of FSH treatment in epigenetic characteristics of sperm in infertile patients with severe oligozoospermia"
    Medical condition: Male infertility
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004848 10017399 FSH LLT
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004391-36 Sponsor Protocol Number: AC-052-402 Start Date*: 2005-05-23
    Sponsor Name:Actelion Pharmaceuticals Ltd.
    Full Title: A multicenter, open-label, single-arm safety study to investigate the effects of chronic TRACLEER® treatment on testicular function in male patients with pulmonary arterial hypertension
    Medical condition: Many endothelin receptor antagonists have profound effects on the histology and function of the testes in animals. These drugs have been shown to induce atrophy of the seminiferous tubules of the t...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: HU (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2016-002498-36 Sponsor Protocol Number: CCN017 Start Date*: 2018-10-12
    Sponsor Name:National Institutes of Health - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Full Title: Clinical Evaluation of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception
    Medical condition: As the clinical trial is intended to investigate a new contraceptive medicinal product, the trial subjects included are not characterized by a specific medical condition.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10065589 Male contraception PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004254-37 Sponsor Protocol Number: 000400 Start Date*: 2022-06-27
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: A randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of FE 999049 for treatment of men with idiopathic infertility
    Medical condition: Idiopathic male infertility (including oligoasthenozoospermia)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038604 - Reproductive system and breast disorders 10021929 Infertility male PT
    Population Age: Adults Gender: Male
    Trial protocol: SE (Trial now transitioned) DE (Trial now transitioned) ES (Trial now transitioned) DK (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-003811-36 Sponsor Protocol Number: 107012 Start Date*: 2007-01-03
    Sponsor Name:NV Organon
    Full Title: A phase III, randomized, double-blind, active-controlled, equivalence clinical trial to investigate the efficacy and safety of a single injection of 100 µg Org 36286 (corifollitropin alfa) to induc...
    Medical condition: Controlled Ovarian Stimulation (COS) to induce the development of multiple follicles in patients participating in an Assisted Reproductive Technology (ART) program
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed) AT (Completed) DK (Completed) CZ (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-003006-27 Sponsor Protocol Number: GEXGP24201 Start Date*: 2012-11-27
    Sponsor Name:Glycotope GmbH
    Full Title: A Phase II, Multicentre, Multinational, Randomised, Assessor-Blind Trial to Investigate the Efficacy and Safety of Various Dosages of FSH-GEX™ in Comparison With 150 IU Gonal-f® in Women Undergoing...
    Medical condition: women undergoing intracytoplasmatic sperm injection (ICSI) as part of assisted reproduction
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004872 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000001-25 Sponsor Protocol Number: OXO-001-201 Start Date*: 2021-08-06
    Sponsor Name:Oxolife S.L.
    Full Title: A phase II, randomised, double-blind, parallel-group, placebo-controlled trial to assess the ongoing pregnancy rate with OXO-001 (200 mg, 300 mg) or placebo at 10 weeks following fresh single blast...
    Medical condition: Infertility treatment and fertility enhancer in women undergoing assisted reproductive techniques or natural reproduction
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: PL (Completed) ES (Ongoing) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2006-000481-37 Sponsor Protocol Number: 142003 Start Date*: 2006-09-07
    Sponsor Name:NV Organon
    Full Title: A randomized, open-label clinical trial to identify predictive factors for controlled ovarian stimulation using a fixed daily dose of 200 IU of recombinant FSH in a GnRH antagonist regimen with or ...
    Medical condition: Controlled Ovarian Stimulation (COS) to induce the development of multiple follicles in patients participating in an Assisted Reproductive Technology (ART) program
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed) DE (Completed) FR (Prematurely Ended) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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