- Trials with a EudraCT protocol (30)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (9)
30 result(s) found for: treosulfan.
Displaying page 1 of 2.
EudraCT Number: 2013-003257-20 | Sponsor Protocol Number: 10MI28 | Start Date*: 2014-05-02 |
Sponsor Name:GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST | ||
Full Title: Evaluation of Treosulfan pharmacokinetics (PK) in children undergoing allogeneic haematopoietic stem cell transplantation (HSCT) | ||
Medical condition: Any paediatric disease with an indication to an allogeneic stem cell transplantation (inclusing leukaemia, primary immunodeficiencies, metabolic disorders and autoimmune or genetic inflammatory bow... | ||
Disease: | ||
Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2005-005913-40 | Sponsor Protocol Number: Treo TM | Start Date*: 2006-01-17 | |||||||||||
Sponsor Name:OSPEDALE POLICLINICO S. MATTEO | |||||||||||||
Full Title: A phase II, multicentre, clinical study evaluating the safety and efficacy of Treosulfan-based conditioning of allogenic transplantation of haemopoietic stem-cells in patients affected by Thalassem... | |||||||||||||
Medical condition: Thalassemia Major | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2006-002856-14 | Sponsor Protocol Number: MC-T.10/MS | Start Date*: 2007-02-21 | |||||||||||
Sponsor Name:medac Gesellschaft für klinische Spezialpräparate mbH | |||||||||||||
Full Title: Randomised, placebo-controlled, three-arm parallel-group, double-blind, multicentre, national clinical phase II study to evaluate the efficacy, safety, and tolerability of intravenous 3 and 6 g/m² ... | |||||||||||||
Medical condition: Secondary progressive or progressive relapsing multiple sclerosis with signs of disease activity in terms of inflammation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-002356-18 | Sponsor Protocol Number: MC-FludT.14/L | Start Date*: 2010-01-12 | ||||||||||||||||
Sponsor Name:medac Gesellschaft für klinische Spezialpräparate mbH | ||||||||||||||||||
Full Title: Clinical phase III trial to compare Treosulfan-based conditioning therapy with Busulfan-based reduced-intensity conditioning (RIC) prior to allogeneic haematopoietic stem cell transplantation in pa... | ||||||||||||||||||
Medical condition: Patients with acute myeloid leukaemia (AML) or myelodysplastic syndrome (MDS) considered ineligible to standard conditioning therapies prior to allogeneic stem cell transplantation. | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DE (Completed) IT (Completed) PL (Completed) FI (Prematurely Ended) FR (Completed) HU (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2012-005414-18 | Sponsor Protocol Number: ZKS000783 | Start Date*: 2014-02-18 | |||||||||||
Sponsor Name:University Medical Center Freiburg | |||||||||||||
Full Title: Thiotepa- Fludarabine- Treosulfan (TFT) conditioning for 2nd allogeneic PBSCT from a different unrelated donor in patients with AML relapsing from prior allogeneic HCT | |||||||||||||
Medical condition: Patients with relapse of AML after the 1st allogeneic PBSCT. | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2013-005508-33 | Sponsor Protocol Number: MC-FludT.16/NM | Start Date*: 2014-09-29 | |||||||||||||||||||||
Sponsor Name:medac Gesellschaft für klinische Spezialpräparate mbH | |||||||||||||||||||||||
Full Title: Clinical phase II trial to compare Treosulfan-based conditioning therapy with Busulfan-based conditioning prior to allogeneic haematopoietic stem cell transplantation (HSCT) in paediatric patients ... | |||||||||||||||||||||||
Medical condition: Male and female children with non-malignant diseases requiring myeloablative conditioning treatment with following allogeneic haematopoietic stem cell transplantation (allo-HSCT) – i.e. primary imm... | |||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Completed) AT (Completed) CZ (Completed) PL (Completed) IT (Ongoing) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2005-003254-10 | Sponsor Protocol Number: UCL 08/0230 | Start Date*: 2009-08-07 | ||||||||||||||||||||||||||
Sponsor Name:University College London | ||||||||||||||||||||||||||||
Full Title: A Phase II Study to determine the efficacy and safety of conventional dose oral Treosulfan in patients with advanced pre-treated Ewing’s Sarcoma | ||||||||||||||||||||||||||||
Medical condition: Advanced and pre-treated Ewing’s Sarcoma | ||||||||||||||||||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: GB (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2013-003604-39 | Sponsor Protocol Number: MC-FludT.17/M | Start Date*: 2014-04-11 | ||||||||||||||||||||||||||
Sponsor Name:medac GmbH | ||||||||||||||||||||||||||||
Full Title: Clinical phase II trial to describe the safety and efficacy of Treosulfan-based conditioning therapy prior to allogeneic haematopoietic stem cell transplantation in paediatric patients with haemato... | ||||||||||||||||||||||||||||
Medical condition: Male and female children with haematologic malignant diseases as acute lymphoblastic leukaemias (ALL), acute myeloid leukaemias (AML), myelodysplastic syndromes (MDS) and juvenile myelomonocytic le... | ||||||||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: DE (Completed) PL (Completed) AT (Completed) CZ (Completed) GB (Completed) IT (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2021-006515-28 | Sponsor Protocol Number: ASST_FARM_2021TMO_FT14 | Start Date*: 2022-06-07 | |||||||||||
Sponsor Name:AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA | |||||||||||||
Full Title: Prospective Phase II study on Safety and Efficacy of Fludarabine plus Treosulfan (14g) (FT14) conditioning regimen for allogeneic Stem Cell Transplantation (allo-SCT) in Acute Myeloid Leukemia (AML... | |||||||||||||
Medical condition: Acute Myeloid Leukemia (AML) patients (=40 <65years) | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-003032-22 | Sponsor Protocol Number: ALL-SCT-ped-FORUM | Start Date*: 2013-02-04 |
Sponsor Name:St. Anna Kinderkrebsforschung GmbH | ||
Full Title: Allogenic stem cell transplantation in children and adolescents with acute lymphoblastic leukaemia - FORUM | ||
Medical condition: acute lymphoblastic leukaemia | ||
Disease: | ||
Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | |
Trial protocol: AT (Ongoing) DE (Restarted) NO (Ongoing) FI (Ongoing) DK (Ongoing) CZ (Completed) NL (Ongoing) SE (Ongoing) IT (Ongoing) BE (Ongoing) ES (Ongoing) SK (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2005-005182-11 | Sponsor Protocol Number: ALLO-TREO | Start Date*: 2005-11-23 | |||||||||||
Sponsor Name:OSPEDALE S. RAFFAELE | |||||||||||||
Full Title: Clinical phase II trial to evaluate the safety and efficacy of treosulfan based conditioning prior to allogenic haematopoietic stem cell transplantation in patients with haematological malignancies. | |||||||||||||
Medical condition: patients with haematologic maliignancies prior to allogenic haematopoietic stem cell | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2023-000169-14 | Sponsor Protocol Number: INES | Start Date*: 2023-05-03 | |||||||||||
Sponsor Name:Fondazione Santobono Pausilipon ONLUS | |||||||||||||
Full Title: Phase II Prospective Multicenter Study of High-Dose Treosulfan/Melphalan as Consolidation Treatment in Newly Diagnosed High-Risk and Very High-Risk Ewing Sarcoma | |||||||||||||
Medical condition: Ewing Sarcoma | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-004095-31 | Sponsor Protocol Number: ModuLung | Start Date*: 2015-07-13 | |||||||||||||||||||||
Sponsor Name:Freistaat Bayer respresented by University of Regensburg represented by Kaufmännischer Direktor | |||||||||||||||||||||||
Full Title: A prospective phase II, randomized multi-center trial of a combined modularized treatment with metronomic low-dose treosulfan, pioglitazone and clarithromycin versus nivolumab in patients with squ... | |||||||||||||||||||||||
Medical condition: locally advanced or metastatic NSCLC, who have progressed during or following a platinum-containing regimen. | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2008-002768-32 | Sponsor Protocol Number: MM03 | Start Date*: 2009-06-08 | |||||||||||
Sponsor Name:Freistaat Bayern | |||||||||||||
Full Title: A prospective phase I/II, one-arm, one-stage multi-center, open label study of lenalidomide in combination with pioglitazone, dexamethasone and metronomic low-dose chemotherapy with treosulfan in p... | |||||||||||||
Medical condition: Multiple myeloma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-002584-41 | Sponsor Protocol Number: CEPOETA-2015-01 | Start Date*: 2016-10-24 |
Sponsor Name:Masarykova univerzita | ||
Full Title: RECURENT NEUROBLASTOMA AND EWING´S SARCOMA: TREOSULPHAN BASED HIGH DOSE CHEMOTHERAPY WITH AUTOLOGOUS PBSC SUPPORT | ||
Medical condition: Ewing's sarcoma, neuroblastoma | ||
Disease: | ||
Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | |
Trial protocol: CZ (Prematurely Ended) HU (Prematurely Ended) | ||
Trial results: (No results available) |
EudraCT Number: 2008-006972-31 | Sponsor Protocol Number: Clo3o | Start Date*: 2008-11-27 | |||||||||||
Sponsor Name:OSPEDALE S. RAFFAELE | |||||||||||||
Full Title: Clinical phase II trial to evaluate the safety and efficacy of clofarabine and treosulfan conditioning prior to peripheral blood stem cells transplantation in paediatric and adult patients with adv... | |||||||||||||
Medical condition: patients affected by advanced haematological malignancies | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-004730-11 | Sponsor Protocol Number: KMT2021001 | Start Date*: 2022-02-18 | |||||||||||
Sponsor Name:Medical University of Vienna | |||||||||||||
Full Title: A prospective, controlled, single-arm pilot study on treosulfan, fludarabine, and cyclophosphamide (TreoFC) as conditioning treatment before haploidentical hematopoietic stem cell transplantation f... | |||||||||||||
Medical condition: Conditioning therapy before haploidentical hematopoietic stem cell transplantation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-003658-13 | Sponsor Protocol Number: EWING2008 | Start Date*: 2009-03-19 | ||||||||||||||||||||||||||
Sponsor Name:Universitaetsklinikum Muenster | ||||||||||||||||||||||||||||
Full Title: EWING 2008 | ||||||||||||||||||||||||||||
Medical condition: Ewing sarcoma Malignant peripheral neuroectodermal tumour Askin tumour Atypical Ewing sarcoma | ||||||||||||||||||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: DE (Completed) AT (Completed) BE (Completed) NL (Completed) SE (Completed) HU (Completed) FI (Completed) LT (Completed) PL (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2008-000664-16 | Sponsor Protocol Number: FLATauto | Start Date*: 2008-02-26 | |||||||||||
Sponsor Name:OSPEDALE S. RAFFAELE | |||||||||||||
Full Title: Clinical phase II trial to evaluate the safety and efficacy of treosulfan combined with cytarabine and fludarabine prior to autologous haematopoietic stem cell transplantation in elderly patients w... | |||||||||||||
Medical condition: elderly patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome | |||||||||||||
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Population Age: Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2022-002435-66 | Sponsor Protocol Number: FLAMSAClax | Start Date*: 2023-02-07 | |||||||||||
Sponsor Name:Heinrich-Heine-Universität Düsseldorf represented by the Coordinating Investigator | |||||||||||||
Full Title: Phase-I/II trial to assess the safety and efficacy of Venetoclax in addition to sequential conditioning with Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for allogeneic blood stem cell tra... | |||||||||||||
Medical condition: Patients with myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) or secondary acute myeloid leukemia (sAML) before stem cell transplantation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Ongoing) | |||||||||||||
Trial results: (No results available) |
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