Clinical trials for cancer

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44353 clinical trials with a EudraCT protocol, of which 7380 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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Trials with a EudraCT protocol (10,212)
Paediatric studies in scope of Art45 of the Paediatric Regulation (712)

10,212 result(s) found for: cancer. Displaying page 114 of 511.

EudraCT Number: 2008-000701-11

Sponsor Protocol Number: CA180227

Start Date*: 2008-11-25

Sponsor Name:Bristol-Myers Squibb International Corporation

Full Title: A Randomized Double-Blind Phase 3 Trial Comparing Docetaxel Combined with Dasatinib to Docetaxel Combined with Placebo in Castration-Resistant Prostate Cancer Revised Protocol 03 incorporating A...

Medical condition: castration-resistant metastatic prostate cancer.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10036909	Prostate cancer metastatic	PT

Population Age: Adults, Elderly

Gender: Male

Trial protocol: DE (Completed) IE (Completed) HU (Completed) FR (Completed) IT (Completed) GB (Completed) CZ (Completed) FI (Completed) SE (Completed) GR (Completed)

Trial results: View results

EudraCT Number: 2004-000971-33

Sponsor Protocol Number: A4061010

Start Date*: 2004-09-24

Sponsor Name:PFIZER

Full Title: Randomized, Placebo-Controlled, Double-Blind, Phase 2 Study of AG-013736 in Combination With Docetaxel Versus Docetaxel Alone in Patients With Metastatic Breast Cancer Preceded by a Phase 1 Evaluat...

Medical condition: METASTATIC BREAST CANCER

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	6.1		10055113		PT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: IT (Completed) CZ (Completed)

Trial results: View results

EudraCT Number: 2018-004721-88

Sponsor Protocol Number: MK-7339-008

Start Date*: 2019-06-05

Sponsor Name:Merck Sharp & Dohme LLC

Full Title: A Phase 3 Study of Pembrolizumab in Combination with Carboplatin/Taxane (Paclitaxel or Nab-paclitaxel) Followed by Pembrolizumab with or without Maintenance Olaparib in the First-line Treatment of ...

Medical condition: Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004864	10029514	Non-small cell lung cancer NOS	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: AT (Trial now transitioned) FR (Trial now transitioned) PL (Trial now transitioned) ES (Ongoing) GB (GB - no longer in EU/EEA) RO (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2004-000864-29

Sponsor Protocol Number: BO17704

Start Date*: 2004-12-01

Sponsor Name:F. Hoffmann-La Roche Ltd.

Full Title: A randomized, double-blind multicenter phase III study of bevacizumab in combination with cisplatin and gemcitabine versus placebo, cisplatin and gemcitabine in patients with advanced or recurrent ...

Medical condition: Advanced or recurrent non-squamous non-small cell lung cancer.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	PT		10061873		7.0

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) CZ (Completed) HU (Completed) ES (Completed) GB (Completed) IT (Completed)

Trial results: View results

EudraCT Number: 2020-002774-27

Sponsor Protocol Number: DS1062-A-U202

Start Date*: 2021-04-16

Sponsor Name:Daiichi Sankyo, Inc.

Full Title: Phase 2, Single-arm, Open-label Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer with Actionable Genomic Alterations and Progressed on or After Applicable Targeted Therapy an...

Medical condition: Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10061873	Non-small cell lung cancer	PT

Population Age: Adults

Gender: Male, Female

Trial protocol: DE (Completed) FR (Trial now transitioned) HU (Completed) NL (Trial now transitioned) IT (Completed)

Trial results: View results

EudraCT Number: 2009-013128-22

Sponsor Protocol Number: HE 42/09

Start Date*: 2010-06-29

Sponsor Name:Hellenic Cooperative Oncology Group

Full Title: Lapatinib and Whole Brain Radiotherapy for patients with brain metastases from lung and breast tumors. A phase II study of the Hellenic Cooperative Oncology Group (HeCOG).

Medical condition: Patients with brain metastases from lung and breast tumors

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.0		10006128	Brain metastases	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GR (Completed)

Trial results: View results

EudraCT Number: 2005-001698-89	Sponsor Protocol Number: Monet	Start Date*: 2006-06-08
Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
Full Title: Molecular profiling of postmenopausal women with breast cancer on neoadjuvant exemestane or tamoxifen
Medical condition: Early or locally advanced breast cancer
Disease:
Population Age: Adults, Elderly		Gender: Female
Trial protocol: GB (Completed)
Trial results: View results

EudraCT Number: 2011-001017-13

Sponsor Protocol Number: CNIO-GI-01-2011

Start Date*: 2011-08-08

Sponsor Name:CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS

Full Title: Phase II trial of individualized selection of chemotherapy in patients with advanced pancreatic carcinoma based on the identification of therapeutic targets in tumor tissue

Medical condition: Advanced pancreatic cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10059326	Pancreatic carcinoma stage IV	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: ES (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2015-000206-18

Sponsor Protocol Number: PM1183-B-005-14-QT

Start Date*: 2015-09-10

Sponsor Name:PharmaMar S.A., Sociedad Unipersonal

Full Title: Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization (QTc Duration) in Patients with Selected Solid Tumors

Medical condition: - small cell lung cancer (SCLC) - head and neck carcinoma (H&N) - neuroendocrine tumors (NETs) - biliary tract carcinoma - endometrial carcinoma - BRCA 1/2-associated metastatic breast carcinoma - ...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.0	100000004864	10048683	Advanced cancer	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: ES (Completed)

Trial results: View results

EudraCT Number: 2009-013022-16

Sponsor Protocol Number: ZonMw 80-82100-98-096/11510014

Start Date*: 2009-10-21

Sponsor Name:Erasmus MC [...]

Full Title: Effecten en bijwerkingen van opioïden: een studie naar de rol van farmacokinetische en farmacogenetische heterogeniteit.

Medical condition: Nociceptive cancer pain for which strong opioids are needed

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10058019	Cancer pain	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Ongoing)

Trial results: (No results available)

EudraCT Number: 2012-005096-13	Sponsor Protocol Number: N12LMB	Start Date*: 2013-08-16
Sponsor Name:the Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital (NKI-AvL)
Full Title: Clinical and pharmacological feasibility study with 2B3-101 in patients with breast cancer and leptomeningeal metastases
Medical condition: Patients with leptomeningeal metastases of breast cancer will be enrolled.
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: NL (Prematurely Ended)
Trial results: (No results available)

EudraCT Number: 2018-004121-80

Sponsor Protocol Number:

Start Date*: 2019-02-05

Sponsor Name:The Christie Hospital NHS Foundation Trust

Full Title: A proof of concept, window trial of the IMmunological effects of AveLumab and Aspirin in Triple-Negative Breast Cancer.

Medical condition: Breast Cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10006187	Breast cancer	PT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2008-000524-82

Sponsor Protocol Number: RMH CCR No 3107

Start Date*: 2008-10-09

Sponsor Name:Royal Marsden Hospital

Full Title: MESH: A Non-Randomised Phase II Trial of Methotrexate in Metastatic Colorectal Cancer with MSH2 Deficiency

Medical condition: Metastatic colorectal cancer resistanct to standard chemotherapy with evidence of deficiency of the mismatch repair gene MSH2, either on immunohistochemistry of tumour histology or on testing of pe...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10052362	Metastatic colorectal cancer	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2007-007059-14

Sponsor Protocol Number: GlutOxa2007

Start Date*: 2007-11-15

Sponsor Name:AZIENDA DI RILIEVO NAZIONALE E DI ALTA SPECIALIZZAZIONE OSPEDALE CIVICO E BENFRATELLI, G.DI CRISTINA E M.ASCOLI

Full Title: Role of the Glutatione reduced in the prevention of neuro-toxicity from Oxaliplatino.

Medical condition: Patients with neoplasia malignant.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10010023	Colorectal neoplasms malignant	HLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Ongoing)

Trial results: (No results available)

EudraCT Number: 2010-021943-41

Sponsor Protocol Number: ABR-33150

Start Date*: 2011-02-17

Sponsor Name:VU Medical Center

Full Title: Treatment optimization of cetuximab in patients with metastatic colorectal cancer based on tumour uptake of 89Zr-labeled cetuximab assessed by PET

Medical condition: advanced colorectal cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.1		10052362	Metastatic colorectal cancer	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Completed)

Trial results: (No results available)

EudraCT Number: 2015-001740-11

Sponsor Protocol Number: 2014/VCC/0015

Start Date*: 2016-01-22

Sponsor Name:Velindre NHS Trust

Full Title: A randomised Phase II/III trial to study radiotherapy dose escalation in patients with oesophageal cancer treated with definitive chemo-radiation with an embedded Phase II trial for patients with a...

Medical condition: Non operable oesophageal cancer patients

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	19.1	100000004864	10030151	Oesophageal cancer	LLT

Population Age: Under 18, Adults, Elderly

Gender: Male, Female

Trial protocol: GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2018-001230-18

Sponsor Protocol Number: PRO-001

Start Date*: 2019-01-30

Sponsor Name:Hellenic Genito-Urinary Cancer Group (HGUCG)

Full Title: Long-term thromboprophylaxis with tinzaparin in high-risk prostate or breast cancer patients. A prospective, randomised, international multicentre, open-label, blinded-endpoint Phase III study. PRO...

Medical condition: Long-term thromboprophylaxis with tinzaparin in high-risk prostate or breast cancer patients.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004865	10049909	Venous thromboembolism prophylaxis	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GR (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2005-005168-94

Sponsor Protocol Number: KKS-77-05

Start Date*: 2006-06-20

Sponsor Name:Philipps-University of Marburg

Full Title: Multicenter Phase II- trial to investigate safety and efficacy of an Adjuvant Therapy with Gemcitabine and Erbitux® in patients with R0 or R1 resected Pancreatic cancer

Medical condition: The aim is to evaluate the feasibility of the combined treatment of cetuximab and gemcitabine in patients with R0-resectable pancreatic cancer and to evaluate if the progression free survival can b...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10033609	Pancreatic carcinoma	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2007-001949-18

Sponsor Protocol Number: P060248

Start Date*: 2007-05-02

Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)

Full Title: Valeur prédictive du statut mutationnel de l'oncogène KRAS sur la réponse aux anticorps monoclonaux recombinants anti-EGFR chez les malades atteints d'un cancer colorectal métastatique. Etude prosp...

Medical condition: Patients traités pour un cancer colorectal métastatique par cetuximab et ayant une cible mesurable permettant de définir la réponse morphologique selon les critères RECIST

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	8.1		10052362	Cancer colorectal métastatique	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Completed)

Trial results: View results

EudraCT Number: 2006-003291-35

Sponsor Protocol Number: ML 19884

Start Date*: 2007-11-26

Sponsor Name:ROCHE

Full Title: Phase II, open label, neoadjuvant study of Bevacizumab in patients with inflammatory or locally advanced breast cancer

Medical condition: Patients with inflammatory or locally advanced operable breast cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	6.1		10021980		PT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: IT (Completed)

Trial results: View results

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The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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