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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,987 result(s) found. Displaying page 261 of 550.
    «« First « Previous 257  258  259  260  261  262  263  264  265  Next» Last»»
    EudraCT Number: 2010-023513-64 Sponsor Protocol Number: GE-067-015 Start Date*: 2011-01-05
    Sponsor Name:GE Healthcare Ltd. and its Affiliates
    Full Title: A Single-Arm Open-Label Multi-Center Study to Determine the Specificity of Flutemetamol (18F) Injection for Excluding the Presence of Brain Amyloid in Healthy Young Adult Subjects Aged 18 to 40
    Medical condition: Healthy volunteers (the absence of brain amyloid will be studied; amyloid is present in Alzheimer's disease)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10001896 Alzheimer's disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) GB (Completed) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022100-42 Sponsor Protocol Number: H9B-MC-BCDT Start Date*: 2011-02-23
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Subcutaneous LY2127399 in Patients with Systemic Lupus Erythematosus (SLE) (ILLUMIN...
    Medical condition: Systemic Lupus Erythematosus (SLE)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10025139 Lupus erythematosus systemic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) LV (Prematurely Ended) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-002257-61 Sponsor Protocol Number: MT103-211 Start Date*: 2011-11-15
    Sponsor Name:Amgen Research (Munich) GmbH
    Full Title: An open label, multicenter, phase II study to evaluate efficacy and safety of the BiTE antibody blinatumomab in adult patients with relapsed/refractory B-precursor acute lymphoblastic leukemia (ALL)
    Medical condition: Adult patients with relapsed / refractory B-precursor ALL.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10000845 Acute lymphoblastic leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023382-22 Sponsor Protocol Number: 9521-CL-0002 Start Date*: 2011-02-21
    Sponsor Name:Astellas Pharma Europe B.V. (APEB)
    Full Title: Phase I/II, multi-center, open label study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor activity of ASP9521 in patients with metastatic castrate-resistant p...
    Medical condition: metastatic castrate-resistant prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036911 Prostate cancer recurrent PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: BE (Prematurely Ended) GB (Prematurely Ended) DE (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023322-21 Sponsor Protocol Number: NP031112-10B04 Start Date*: 2011-04-13
    Sponsor Name:Noscira S.A
    Full Title: A multicenter, Randomized, Double-blind, Placebo-controlled, 4-arm, 26 week Parallel-Group Study to evaluate the Efficacy, Safety and Tolerability of Two Oral Doses and Two Regimes of Tideglusib vs...
    Medical condition: Alzheimer's Disease (mild to moderate)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029205 - Nervous system disorders 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) FI (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004619-23 Sponsor Protocol Number: CC-10004-PSA-001 Start Date*: 2007-02-05
    Sponsor Name:Celgene Corporation
    Full Title: A Phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-group, efficacy and safety study of two dose regimens of CC-10004 in subjects with active psoriatic arthritis
    Medical condition: Active psoriatic arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) NL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001755-36 Sponsor Protocol Number: 2939117 Start Date*: 2006-08-09
    Sponsor Name:Orion Corporation Orion Pharma, FI-02200 Espoo, Finland
    Full Title: Efficacy and safety of Stalevo in subjects with early wearing-off identified using a screening tool WOQ-9; An open, non-randomised, multinational, multi-centre 6-week direct switch study in levodop...
    Medical condition: Parkinson’s disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10061536 Parkinson's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004257-14 Sponsor Protocol Number: 0974-011 Start Date*: 2007-02-21
    Sponsor Name:Merck Sharp & Dohme (MSD)
    Full Title: A Multicenter, Double-Blind, Placebo and Active-Controlled, Parallel Group Study to Compare the Efficacy and Safety of Oral MK-0974 With Placebo and Zolmitriptan for the Acute Treatment of Migraine...
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027599 Migraine LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001169-40 Sponsor Protocol Number: 107192, 107214 Start Date*: 2006-04-19
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase IIb, controlled, randomised, multicenter, observer blinded study to demonstrate the lot-to-lot consistency of three consecutive production lots of low dose of influenza vaccine adjuvanted w...
    Medical condition: Immunization against influenza in male and female subjects aged 60 years and older
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed) EE (Completed) DE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-002011-24 Sponsor Protocol Number: 42205525 Start Date*: 2008-05-22
    Sponsor Name:European Group for Blood and Marrow Transplantation (EBMT)
    Full Title: Dose-reduced versus standard conditioning followed by allogeneic stem cell transplantation in patients with MDS or sAML: A randomised phase III study
    Medical condition: Myelodysplastic syndromes and secondary acute myeloid leukaemia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) BE (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002855-15 Sponsor Protocol Number: CTCH346A2211E1 Start Date*: 2004-12-29
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A long-term extension to a randomized, double-blind, placebo-controlled, stratified, parallel-group, multicenter, dose-ranging study evaluating four oral doses of TCH346 (1.0, 2.5, 7.5 and 15mg) ad...
    Medical condition: Amyotrophic Lateral Sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-002894-21 Sponsor Protocol Number: CDAR328A2409 Start Date*: 2005-06-21
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 12-week, randomized, double-blind, placebo-controlled, parallel group, multicenter study to evaluate the efficacy, safety and tolerability of darifenacin (7.5 mg o.d. with voluntary up-titration...
    Medical condition: Overactive bladder (OAB)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) HU (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003630-18 Sponsor Protocol Number: ICLA-09-CSI2 Start Date*: 2006-01-31
    Sponsor Name:Arpida AG
    Full Title: Phase 3, Randomized, Investigator-Blind, Multi-Center Study to Evaluate Efficacy and Safety of Intravenous Iclaprim Versus Intravenous Linezolid in Complicated Skin and Skin Structure Infections
    Medical condition: Complicated skin and skin structure infections are predominantly caused by the following Gram-positive pathogens: Staphylococcus aureus, including methicillin-resistant strains, beta hemolytic stre...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10040786 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) GB (Completed) DE (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001369-34 Sponsor Protocol Number: ACT12339 Start Date*: 2012-10-26
    Sponsor Name:Sanofi-aventis recherche & développement
    Full Title: Double-blind, randomized, 8-week placebo-controlled and 16-week open label extension study investigating the Safety, Pharmacokinetics and Pharmacodynamics of SAR100842 Given Orally to Patients with...
    Medical condition: Systemic Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    15.1 10028395 - Musculoskeletal and connective tissue disorders 10042953 Systemic sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002563-10 Sponsor Protocol Number: BAY86-4875/15961 Start Date*: 2013-06-06
    Sponsor Name:Bayer HealthCare AG
    Full Title: Multicenter open-label study to evaluate efficacy of gadobutrol-enhanced cardiac magnetic resonance imaging (CMRI) for detection of significant coronary artery disease (CAD) in subjects with known ...
    Medical condition: Subjects with known or suspected Coronary Artery Disease (CAD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-000192-13 Sponsor Protocol Number: COLO/DPI/02/11 Start Date*: 2011-04-28
    Sponsor Name:Forest Laboratories UK Ltd.
    Full Title: A 7-day open-label pharmacokinetic study to investigate the systemic absorption of colistimethate sodium after inhalation of dry powder colistimethate sodium for inhalation (Colobreathe® 125mg) in ...
    Medical condition: cystic fibrosis subjects with chronic pulmonary infection with Pseudomonas aeruginosa
    Disease: Version SOC Term Classification Code Term Level
    13.1 10010331 - Congenital, familial and genetic disorders 10011763 Cystic fibrosis lung PT
    13.1 10010331 - Congenital, familial and genetic disorders 10011762 Cystic fibrosis PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003069-42 Sponsor Protocol Number: CRx-102-007 Start Date*: 2007-10-31
    Sponsor Name:CombinatoRx, Incorporated
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER STUDY TO EVALUATE THE SUPERIORITY OF CRX-102 OVER EACH OF ITS COMPONENTS WHEN GIVEN TO SUBJECTS WITH ACTIVE RHEUMATOID ARTHRITIS (RA)
    Medical condition: RHEUMATOID ARTHRITIS (RA)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Prematurely Ended) GB (Prematurely Ended) HU (Completed) LT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005094-30 Sponsor Protocol Number: 0524B-022 Start Date*: 2006-01-04
    Sponsor Name:Merck & Co., Inc
    Full Title: A Multicenter, Randomized, Double-Blind, "Factorial" Design Study to Evaluate the Lipid-Altering Efficacy and Safety of MK-0524B Combination Tablet in Patients With Primary Hypercholesterolemia or ...
    Medical condition: Hypercholesterolaemia
    Disease: Version SOC Term Classification Code Term Level
    8.0 10020603 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) SE (Completed) DK (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004250-26 Sponsor Protocol Number: CO-338-010 Start Date*: 2012-02-02
    Sponsor Name:Clovis Oncology Inc.
    Full Title: A Phase I/II, Open-Label, Safety, Pharmacokinetic, and Preliminary Efficacy Study of Oral Rucaparib in Patients with gBRCA Mutation Ovarian Cancer, or Other Solid Tumor
    Medical condition: Patients with locally advanced or metastatic solid tumors including lymphoma and germline BRCA (gBRCA) ovarian cancer
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10049280 Solid tumour LLT
    19.0 100000004864 10033130 Ovarian cancer NOS LLT
    19.0 100000004864 10025315 Lymphoma malignant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) ES (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016035-35 Sponsor Protocol Number: NAI113678 Start Date*: 2009-11-13
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: An Open-Label, Multi-Center, Single Arm Study to Evaluate the Safety and Tolerability of Intravenous Zanamivir in the Treatment of Hospitalized Adult, Adolescent and Pediatric Subjects with Confirm...
    Medical condition: Hospitalized adult, adolescent and pediatric subjects with influenza infection.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10022000 Influenza LLT
    Population Age: In utero, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Completed) DE (Completed) GB (Completed) Outside EU/EEA
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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