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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    26,035 result(s) found. Displaying page 440 of 1,302.
    «« First « Previous 436  437  438  439  440  441  442  443  444  Next» Last»»
    EudraCT Number: 2014-002841-23 Sponsor Protocol Number: ALX0171-C104 Start Date*: 2014-09-22
    Sponsor Name:Ablynx NV
    Full Title: A Phase I/IIa Multicentre Study in Otherwise Healthy Infants and Toddlers Hospitalised For and Diagnosed With Respiratory Syncytial Virus Lower Respiratory Tract Infection, Consisting of an Open-la...
    Medical condition: Respiratory Syncytial Virus Lower Respiratory Tract Infection
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10061603 Respiratory syncytial virus infection PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) SK (Completed) BE (Completed) ES (Completed) EE (Prematurely Ended) LV (Prematurely Ended) BG (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-010563-17 Sponsor Protocol Number: FF1 Start Date*: 2009-10-02
    Sponsor Name:Stichting Pediatrisch Onderzoek Enschede
    Full Title: The protective effect of a nasal corticosteroid (Avamys) on exercise induced airway obstruction in cold air.
    Medical condition: Exercise induced airway obstruction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003557 Asthma exercise induced LLT
    9.1 10001723 Allergic rhinitis LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001222-27 Sponsor Protocol Number: EU-IIT-006 Start Date*: 2007-11-06
    Sponsor Name:Imperial College London
    Full Title: The effect of Pioglitazone on vascular and ventricular function in people with type 2 diabetes PICCOLA
    Medical condition: Diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus LLT
    9.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001257-25 Sponsor Protocol Number: BC20779 Start Date*: 2007-07-18
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Multicenter, double-blind, randomized, placebo-controlled, dose ranging phase 2 study to investigate efficacy, safety, tolerability and pharmacokinetics of the DPP-IV inhibitor RO4876904 in patient...
    Medical condition: Type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-008275-34 Sponsor Protocol Number: Edi-Omeg3-08001 Start Date*: 2009-08-20
    Sponsor Name:NHS Lothian [...]
    1. NHS Lothian
    2. University of Edinburgh
    Full Title: The Effect of Omega-3 Fatty Acids on Non-Alcoholic Fatty Liver Disease
    Medical condition: Non-alcoholic fatty liver disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029530 Non-alcoholic fatty liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008293-31 Sponsor Protocol Number: Pompe phys 03 Start Date*: 2009-02-10
    Sponsor Name:Erasmus MC Sophia
    Full Title: Early introduction in the Netherlands of alglucosidase alfa manufactured in a 4000 liter bioreactor
    Medical condition: Glycogen Storage Disease Type II (Pompe's Disease)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036143 Pompe's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001232-42 Sponsor Protocol Number: RGHT000270 Start Date*: 2006-06-14
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: The Pharmacogenetics of Aspirin Resistance
    Medical condition: Aspirin resistance: Vascular diseases are common problems and aspirin is used as an anti-platelet drug to prevent thrombosis. However, aspirin's anti-platelet effect may not be uniform in all patie...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003739-22 Sponsor Protocol Number: GAL-01-2007 Start Date*: 2007-10-04
    Sponsor Name:GALSOR S.R.L.
    Full Title: Safety and efficacy (for the symptom remission) of the treatment adjuvant of the antibiotic therapy of the acute episode of sinusitis (acute, subacute, chronic)with Ecballium Elaterium (SINUclean D...
    Medical condition: Acute sinusitis or exacerbation of subacute or chronic sinusitis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040753 Sinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003741-33 Sponsor Protocol Number: NRA6290020 Start Date*: 2007-12-17
    Sponsor Name:Barts and the London NHS Trust
    Full Title: A Study To Determine The Optimum Serum IGF-I Range In Patients With Acromegaly Treated With Pegvisomant
    Medical condition: Acromegaly
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000599 Acromegaly LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-018716-33 Sponsor Protocol Number: PHRN09-AM/MUCIS Start Date*: 2010-10-21
    Sponsor Name:CHRU de TOURS
    Full Title: Etude de l'efficacité du méthotrexate en adjonction d'un anti-histaminique H1 dans le traitement de l'urticaire chronique idiopathique sévère réfractaire aux anti-H1 seuls : essai randomisé.
    Medical condition: urticaire chronique idiopathique sévère
    Disease: Version SOC Term Classification Code Term Level
    12.1 10009159 Chronic urticaria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018730-51 Sponsor Protocol Number: 113977 Start Date*: 2010-11-24
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase IIIb, open, multi-centre, controlled study to assess the long-term persistence of antibodies after a single dose of GlaxoSmithKline (GSK) Biologicals’ meningococcal serogroup ACWY tetanus-t...
    Medical condition: Vaccination of children 2 to 10 years of age against invasive disease caused by meningococcal serogroups A, C, W-135, and Y.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10027274 Meningococcal infection LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018738-27 Sponsor Protocol Number: CF2110399 Start Date*: 2010-06-02
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A Randomized, Double Blind, Parallel Group, Placebo Controlled 28 Day Study to Investigate the Safety, Tolerability and Pharmacodynamics of SB-656933 in Patients with Cystic Fibrosis
    Medical condition: Cystic fibrosis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011763 Cystic fibrosis lung LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018740-13 Sponsor Protocol Number: acareoxt01 Start Date*: 2011-08-25
    Sponsor Name:University Medical Center Groningen
    Full Title: Short- and long-term effects of oxytocin on empathy and social behaviour in autistic and antisocial male adults.
    Medical condition: Antisocial personality disorder Autism spectrum disorder
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002822 Antisocial personality disorder LLT
    12.1 10063844 Autism spectrum disorder LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013890-16 Sponsor Protocol Number: P06120 Start Date*: 2010-05-28
    Sponsor Name:GEDII - Grupo de Estudo da Doença inflamatória Intestinal
    Full Title: Herica - Histological and Endoscopic evaluation of Remission induced by Infliximab in moderately to severely active ulcerative Colitis Patients
    Medical condition: This national, multi-centre, open-label pilot study will assess the histologic remission in patients with moderate to severe active ulcerative colitis under infliximab treatment who have had an ina...
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: PT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013929-42 Sponsor Protocol Number: 39588146AHF2001 Start Date*: 2010-07-08
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of JNJ-39588146 in Subjects with Heart Failure
    Medical condition: JNJ-39588146 is being developed for the treatment of heart failure.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016925-32 Sponsor Protocol Number: HSJD-CAFEINA-09 Start Date*: 2010-03-09
    Sponsor Name:Hospital Sant Joan de Déu
    Full Title: "CAFEÍNA COMO TRATAMIENTO DE LAS APNEAS EN PACIENTES CON BRONQUIOLITIS AGUDA"
    Medical condition: TRATAMIENTO DE LAS APNEAS EN PACIENTES CON BRONQUIOLITIS AGUDA
    Disease: Version SOC Term Classification Code Term Level
    9 10002972 Apnea LLT
    9 10000686 Acute bronchiolitis LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016930-29 Sponsor Protocol Number: MeIn/09/Ran-Car/01 Start Date*: 2010-04-15
    Sponsor Name:MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
    Full Title: Ranolazine to treat early cardiotoxicity induced by antitumor drugs
    Medical condition: Patients who completed standard dose chemotherapy for the treatment of non-Hodgkin lymphoma or the adjuvant treatment of breast cancer or colorectal cancer.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025322 HLGT
    9.1 10006200 PT
    9.1 10009944 PT
    9.1 10038038 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010830-23 Sponsor Protocol Number: H8O-EW-GWDL Start Date*: 2009-08-21
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: Efficacy of Once-Weekly Exenatide versus Once or Twice Daily Insulin Detemir in Patients with Type 2 Diabetes Treated with Metformin Alone or in Combination with Sulphonylurea
    Medical condition: Diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10012594 Diabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2009-010834-23 Sponsor Protocol Number: C-09-006 Start Date*: 2009-04-30
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A multi-center, double-masked study of the safety and efficacy of DuoTrav APS compared to DuoTrav in patients with open-angle glaucoma or ocular hypertension
    Medical condition: Open-angle glaucoma (with or without pseudoexfoliation or pigment dispersion component) or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-010863-18 Sponsor Protocol Number: NL26548.101.09 Start Date*: 2010-06-25
    Sponsor Name:Amphia ziekenhuis
    Full Title: The additive effect of short contact tar-derivates to UVB therapy in “en plaque” psoriasis: a prospective single blind unicenter randomized clinical trial
    Medical condition: Psoriasis patient getting UVB lighttherapy in a dermatological daycare center
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015581 Exacerbation of psoriasis LLT
    9.1 10037153 Psoriasis LLT
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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