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Clinical trials for Treatment as Usual

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,089 result(s) found for: Treatment as Usual. Displaying page 10 of 105.
    EudraCT Number: 2008-004625-42 Sponsor Protocol Number: KardioPII Start Date*: 2009-01-09
    Sponsor Name:Asklepios Kliniken Hamburg GmbH
    Full Title: Percutaneous Intramyocardial Cell Therapy After Acute Myocardial Infarction using Bone Marrow Mononuclear Cells
    Medical condition: Acute myocardial infarction (LVEF<45%) ICD10: I21.9
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004445-42 Sponsor Protocol Number: 1 Start Date*: 2007-05-22
    Sponsor Name:Institut for Pharmacology and Toxicology
    Full Title: Pharmacokinetics of Cetriaxon in bone
    Medical condition: hip replacement
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003898-42 Sponsor Protocol Number: 2 Start Date*: 2008-03-19
    Sponsor Name:Institut for Pharmacology and Toxicology
    Full Title: Pharmacokinetica of levofloxacine in bone
    Medical condition: hip or knee replacement
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002211-25 Sponsor Protocol Number: bot001 Start Date*: 2013-04-08
    Sponsor Name:Oslo University Hospital, Dept of Urology
    Full Title: Prevention of bladder dysfunction in acute spinal cord injury A double-blind, randomized, placebo-controlled study to explore the effect of early treatment with Onabotulinumtoxin A in patients ...
    Medical condition: Bladder dysfunction after acute spinal cord injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2022-000603-12 Sponsor Protocol Number: 80655 Start Date*: 2022-08-05
    Sponsor Name:Radboud University
    Full Title: Oxytocin and reactivity to infant signals in mothers with postpartum depression
    Medical condition: We examine the effects of oxytocin on mother-infant interaction among mothers with a postpartum depression
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-005508-37 Sponsor Protocol Number: PI2021_843_0197 Start Date*: 2021-12-20
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Evaluation of plasma concentrations of intravenous lidocaine and epidural ropivacaine when used in combination in major abdominal surgery
    Medical condition: major abdominal surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003944-38 Sponsor Protocol Number: 15-PP-13 Start Date*: 2016-04-19
    Sponsor Name:CHU NICE
    Full Title: Treatment of the oral aphtose récidivante and idiopathique of the adult by probiotics Double-blind randomized interventional study versus placebo
    Medical condition: aphtous stoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-004857-14 Sponsor Protocol Number: 1 Start Date*: 2009-05-29
    Sponsor Name:Psykiatrisk Center Rigshospitalet
    Full Title: The effects of erythropoietin on depressive symptoms and neurocognitive deficits in patients with treatment resistant depression and in patients with remitted bipolar disorder – a proof of concept ...
    Medical condition: Treatment resistant depression and bipolar disorder in remission.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050648 Blood erythropoietin LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-004802-24 Sponsor Protocol Number: NL68556.091.18 Start Date*: 2019-05-20
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Optimizing timing of glucocorticoid treatment in children with congenital adrenal hyperplasia
    Medical condition: Congenital adrenal hyperplasia (CAH) is a disorder of adrenal steroid synthesis leading to cortisol deficiency and an increase in androgen production.Treatment in children consists of hydrocortis...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-000505-72 Sponsor Protocol Number: 2019-000505-72 Start Date*: 2019-05-13
    Sponsor Name:Transparency in Healthcare
    Full Title: Pragmatic trial baricitinib versus First biological in “Tight Control” Patients suffering from Rheumatoid Arthritis (PERFECT)
    Medical condition: Pragmatic trial baricitinib versus First biological in “Tight Control” Patients suffering from Rheumatoid Arthritis (PERFECT)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002076-41 Sponsor Protocol Number: C16019 Start Date*: 2014-06-17
    Sponsor Name:Takeda Development Center Americas, Inc.
    Full Title: A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Citrate (MLN9708) Maintenance Therapy in Patients With Multiple Myeloma Following Autologous Stem Cell Transplant
    Medical condition: Newly diagnosed multiple myeloma (NDMM) following induction therapy and autologous stem cell transplant (ASCT)
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) SE (Completed) DK (Completed) IT (Completed) PT (Completed) ES (Completed) AT (Completed) HU (Completed) DE (Completed) NL (Completed) GR (Completed) PL (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2019-002101-21 Sponsor Protocol Number: ARGX-113-1803 Start Date*: 2020-05-25
    Sponsor Name:argenx BV
    Full Title: A Phase 3, Multicenter, Open-label, Long-term Trial to Evaluate the Safety and Efficacy of Efgartigimod (ARGX-113) 10 mg/kg Intravenous in Adult Patients With Primary Immune Thrombocytopenia
    Medical condition: Primary immune thrombocytopenia
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004851 10050245 Autoimmune thrombocytopenia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) ES (Completed) HU (Trial now transitioned) FR (Completed) BE (Completed) CZ (Trial now transitioned) BG (Completed) DE (Completed) GB (GB - no longer in EU/EEA) AT (Completed) IT (Trial now transitioned) PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-004794-10 Sponsor Protocol Number: A3841047 Start Date*: 2006-12-14
    Sponsor Name:Pfizer Limited
    Full Title: A CLUSTER RANDOMIZED TRIAL ON CARDIOVASCULAR RISK FACTOR MANAGEMENT: CADUET® VERSUS USUAL CARE IN SUBJECTS WITH HYPERTENSION AND ADDITIONAL CARDIOVASCULAR RISK FACTORS IN CLINICAL PRACTICE
    Medical condition: HYPERTENSION AND ADDITIONAL CARDIOVASCULAR RISK FACTORS.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2020-001209-22 Sponsor Protocol Number: PRINCIPLE Start Date*: 2020-03-26
    Sponsor Name:University of Oxford / Clinical Trials and Research Governance
    Full Title: Platform Randomised trial of INterventions against COVID-19 In older peoPLE
    Medical condition: Suspected COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10053983 Corona virus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-004016-11 Sponsor Protocol Number: 2305 Start Date*: 2016-06-30
    Sponsor Name:University of Bristol
    Full Title: What is the clinical and cost effectiveness of benzocaine/phenazone ear drops for reducing antibiotic consumption and ear pain in children aged between 6 months and 10 years presenting to primary c...
    Medical condition: Acute otitis media
    Disease: Version SOC Term Classification Code Term Level
    20.0 10013993 - Ear and labyrinth disorders 10014020 Ear pain PT
    20.1 10013993 - Ear and labyrinth disorders 10065838 Middle ear inflammation PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-000551-81 Sponsor Protocol Number: HZA116492 Start Date*: 2016-08-01
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A 6-month, open label, randomised, efficacy study to evaluate fluticasone furoate (FF, GW685698)/vilanterol (VI, GW642444) Inhalation Powder delivered once daily via the Dry Powder Inhaler Ellipta™...
    Medical condition: Subject with persistent asthma
    Disease: Version SOC Term Classification Code Term Level
    19.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001692-37 Sponsor Protocol Number: ketamine_plus_CBASP Start Date*: 2021-02-24
    Sponsor Name:University Hospital Tuebingen
    Full Title: Pharmacologic treatment augmentation in chronic depression randomized, controlled, double blinded, phase II study
    Medical condition: Males and females between 18-64 years with a diagnosis of chronic depression
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10066555 Chronic depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005480-28 Sponsor Protocol Number: IJG-FER-2012 Start Date*: 2013-05-21
    Sponsor Name:Institut d?Investigació en Atenció Primaria IDIAP Jordi Gol
    Full Title: Effectiveness of adaptation of the dose of iron supplementation in pregnancy on maternal-child health. Randomized clinical trial (ECLIPSES)
    Medical condition: Pregnant women, less than 12 week of gestations,without anemia (Hb <110 d / dL) in the pre-analytical at 12 weeks
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002094-22 Sponsor Protocol Number: 2013MM002B Start Date*: 2013-08-29
    Sponsor Name:Royal Brompton and Harefield NHS Foundation Trust (RB&HFT)
    Full Title: Comparison of ultra-low-dose Oral versus Transdermal Hormone Therapy on coagulation activation and metabolic risk factors for Cardiovascular Disease
    Medical condition: The effect of oestrogen replacement therapy taken either orally or transdermally and observing any likely benefit of both these therapies on the risks Venous thromobembolic events and cardiovascul...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038604 - Reproductive system and breast disorders 10027309 Menopause and related conditions HLGT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-024271-10 Sponsor Protocol Number: V00162GL203 Start Date*: 2011-07-06
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: Urodynamic effect of one single vaginal application of 2 mL of V0162 gel (0.8%) in post-menopausal women with overactive bladder
    Medical condition: Overactive Bladder symptoms.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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