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The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    9,510 result(s) found for: e. Displaying page 131 of 476.
    «« First « Previous 127  128  129  130  131  132  133  134  135  Next» Last»»
    EudraCT Number: 2010-022945-52 Sponsor Protocol Number: ADVL0516 Start Date*: 2012-01-26
    Sponsor Name:Children’s Oncology Group
    Full Title: A Phase 1 Study of BMS-354825 (Dasatinib) in Children with Recurrent/Refractory Solid Tumors or Imatinib Resistant Ph+ Leukemia.
    Medical condition: Refractory solid tumors Ph+ leukemia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10065252 Solid tumor LLT
    14.1 10022891 - Investigations 10034877 Philadelphia chromosome positive LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-001875-57 Sponsor Protocol Number: 106524 Start Date*: 2017-03-13
    Sponsor Name:Erasmus University Medical Center Rotterdam
    Full Title: Desmopressin and FVIII concentrate combination treatment in non-severe hemophilia A patients undergoing minor interventions
    Medical condition: Hemophilia A
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10060613 Hemophilia A (Factor VIII) LLT
    20.0 100000004850 10053753 Hemophilia A without inhibitors LLT
    20.0 100000004850 10060612 Hemophilia A LLT
    Population Age: Adolescents, Under 18, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001770-42 Sponsor Protocol Number: 4745 Start Date*: 2018-10-24
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: A multicenter phase II non-randomised trial assessing the efficacy of Domatinostat plus avelumab in patients with previously treated advanced mismatch repair proficient oesophagogastric and colore...
    Medical condition: Advanced gastrooesophageal and colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10009944 Colon cancer PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10042080 Stomach cancer LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10030137 Oesophageal adenocarcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-000644-34 Sponsor Protocol Number: 108638 Start Date*: 2016-06-09
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase III, open, randomised, multicentre study to assess the immunogenicity and safety of GlaxoSmithKline (GSK) Biologicals’ combined reduced antigen content diphtheria-tetanus toxoids and acellu...
    Medical condition: Healthy volunteers (Immunisation against diphtheria, tetanus and pertussis)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10021881 Infections and infestations SOC
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2015-001514-97 Sponsor Protocol Number: 114541 Start Date*: 2015-05-27
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A Phase 3, observer blind, randomized, non-influenza vaccine comparator-controlled, multi-country and multi-centre study of the efficacy of GSK Biologicals’ quadrivalent, inactivated, split virion,...
    Medical condition: Healthy volunteers (Immunization against influenza in male and female subjects 3 to 8 years of age inclusive)
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-000162-40 Sponsor Protocol Number: IFN 001 Start Date*: 2005-09-06
    Sponsor Name:Helix Product Development (Ireland) Limited
    Full Title: Treatment of genital warts with Interferon alpha-2b Cream: a randomized, double blind, placebo-controlled study
    Medical condition: Condylomata acuminata (genital warts)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004574-11 Sponsor Protocol Number: CS1008-A-E202 Start Date*: 2009-05-26
    Sponsor Name:Daiichi Sankyo Development Limited
    Full Title: RANDOMISED, DOUBLE-BLINDED, PLACEBO- CONTROLLED PHASE 2 STUDY OF CS-1008 IN COMBINATION WITH CARBOPLATIN/PACLITAXEL IN CHEMOTHERAPY NAÏVE SUBJECTS WITH METASTATIC OR UNRESECTABLE NON-SMALL CELL LU...
    Medical condition: Treatment of metastatic or unresectable non small cell lung cancer (NSCLC) with CS 1008 or placebo first in combination with carboplatin/paclitaxel then as monotherapy in the first line setting
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059515 Non-small cell lung cancer metastatic PT
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029521 Non-small cell lung cancer stage IIIB PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-006411-20 Sponsor Protocol Number: CHUBX 2008/20 Start Date*: 2009-02-13
    Sponsor Name:CHU de Bordeaux
    Full Title: EVALUATION PRONOSTIQUE DE LA TOMOGRAPHIE PAR EMISSION DE POSITONS COUPLEE AU SCANNER (TEP-TDM) AU FLUOROMISONIDAZOLE MARQUE AU FLUOR 18 (18F-FMISO) DANS LES CANCERS EPIDERMOIDES DES VOIES AERODIGES...
    Medical condition: CANCERS EPIDERMOIDES DES VOIES AERODIGESTIVES SUPERIEURES
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007050 Cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000330-50 Sponsor Protocol Number: EC07/90285 Start Date*: 2008-10-27
    Sponsor Name:Organisation name was not entered
    Full Title: EFECTO DE SUPLEMENTACIÓN NUTRICIONAL ENRIQUECIDA CON ÁCIDOS GRASOS OMEGA-3 EN EL ESTRÉS OXIDATIVO Y METABOLISMO LIPÍDICO DE PACIENTES CON PROCESOS ONCOLÓGICOS DEL ÁREA OTORRINOLARINGOLÓGICA (ORL) ...
    Medical condition: Determinar las modificaciones inducidas por la suplementación especifica de ácidos grasos omega3 en el estrés oxidativo y estado inflamatorio en pacientes oncológicos sometidos a tratamiento radiot...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061273 Malnutrition LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002077-12 Sponsor Protocol Number: MR-2008/001 Start Date*: 2008-09-24
    Sponsor Name:AZIENDA OSPEDALIERA DI PERUGIA
    Full Title: “Fenoldopam end Renal failure” (FENO-HSR)
    Medical condition: Renal failure from ipoperfusion post Cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10000821 Acute kidney failure LLT
    14.1 10038359 - Renal and urinary disorders 10048988 Renal artery occlusion PT
    14.1 10047065 - Vascular disorders 10002482 Angiosclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022762-27 Sponsor Protocol Number: PEN1011 Start Date*: 2010-11-09
    Sponsor Name:Klinisk Farmakologisk Afdeling, Bispebjerg
    Full Title: Studiets formål er, at undersøge hvorvidt v-penicillin og trimethoprim inducerer oxidativt stress i raske frivillige forsøgsdeltagere. En eventuel induktion vurderes ud fra målinger på 8-oxoGuo- og...
    Medical condition: Oxidative stress induced by antibiotics
    Disease: Version SOC Term Classification Code Term Level
    12.1 10021789 Infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-021399-26 Sponsor Protocol Number: CUERVO-07 Start Date*: 2011-01-12
    Sponsor Name:Fundación para la Formación y la Investigación de los profesionales de la Salud (FUNDESALUD)
    Full Title: ENSAYO CLÍNICO CRUZADO PARA EVALUAR LA EFICACIA DEL TRATAMIENTO CON CITRATO DE FENTANILO ORAL TRANSMUCOSA DE LA DISNEA DE ESFUERZO EN PACIENTES CON CÁNCER AVANZADO
    Medical condition: Disnea de esfuerzo en pacientes con cáncer avanzado
    Disease: Version SOC Term Classification Code Term Level
    13 10013588 Disnea de esfuerzo LLT
    13 10058019 Dolor canceroso PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005884-25 Sponsor Protocol Number: 1553-B-211 Start Date*: 2012-03-13
    Sponsor Name:Servicio de Endocrinologia y Nutricion. Hospital Universitari Bellvitge
    Full Title: Study of the effectiveness of bariatric surgery in the treatment of type II Diabetes Mellitus in patients with grade I obesity
    Medical condition: Diabetes mellitus 2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001688-22 Sponsor Protocol Number: 01CCRe-IV Start Date*: 2013-08-23
    Sponsor Name:Servicio de Cirugía General y Digestiva Hospital Universitario de Bellvitge
    Full Title: Randomized multicenter trial in colorectal cancer patients with non-resectable metastasis. Impact of tumor resection versus chemotherapy alone in survival.
    Medical condition: Cancer colorectal stage IV with synchronous non-resectable metastasis.
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010035 Colorectal cancer stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005068-29 Sponsor Protocol Number: C2006-01 Start Date*: Information not available in EudraCT
    Sponsor Name:A.P. Pharma, Inc.
    Full Title: A Pivotal Phase 3 Observer-Blind, Randomized Clinical Trial of the Efficacy and Safety of APF530 Compared to Aloxi® for the Prevention of Acute-Onset and Delayed-Onset Chemotherapy-Induced Nausea a...
    Medical condition: Chemotherapy Induced Nausea and Vomiting
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054133 Prophylaxis of nausea and vomiting LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000233-18 Sponsor Protocol Number: AIO KRK 0205 Start Date*: 2008-04-09
    Sponsor Name:Universität zu Köln
    Full Title: Phase I/II Studie zum Einsatz von Capecitabin und Oxaliplatin (XELOX) in Kombination mit Bevacizumab und Imatinib in der Erstlinientherapie von Patienten mit fortgeschrittenem kolorektalem Karzinom
    Medical condition: fortgeschrittenes kolorektalen Karzinom mit inoperablen Metastasen
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010035 Colorectal cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007241-12 Sponsor Protocol Number: PH-L19SIPI131-07/07 Start Date*: 2008-10-06
    Sponsor Name:Philogen S.p.A.
    Full Title: A PHASE I/II DOSE FINDING AND EFFICACY STUDY OF THE TUMOUR TARGETING HUMAN 131I-L19SIP MONOCLONAL ANTIBODY IN PATIENTS WITH CANCER
    Medical condition: Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007050 Cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-005327-41 Sponsor Protocol Number: INT0211 Start Date*: 2012-04-05
    Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI
    Full Title: Clinical trial randomized and controlled to compare the analgesic efficacy of the association zoledronic acid and 153Sm-lexidronam vs zoledronic acid in patients with skeletal metastases from hormo...
    Medical condition: Population enrolled in the study is represented by patients bearing advanced prostatic cancer with skeletal metastases and bone pain cancer-associated and treated with analgesic drugs
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10005993 Bone metastases LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001905-42 Sponsor Protocol Number: LDLL600.201 Start Date*: 2014-10-23
    Sponsor Name:AOP Oprhan Pharmaceuticals AG
    Full Title: Open-label Two-arm PD and PK Study of Landiolol in Patients with Tachycardic Atrial Fibrillation or Atrial Flutter
    Medical condition: 20 Caucasian patients with tachycardic atrial fibrillation (AF) or atrial flutter (AFL)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004849 10003663 Atrial flutter/ fibrillation LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001056-35 Sponsor Protocol Number: TXA Start Date*: 2014-11-24
    Sponsor Name:IRCCS Istituto Giannina Gaslini
    Full Title: The Effectiveness and Population Pharmacokinetics and Pharmacogenomics of a Reduced Dose of Tranexamic Acid for Craniosynostosis Surgery: A multicenter study. The TXA Study.
    Medical condition: craniosynostosis
    Disease: Version SOC Term Classification Code Term Level
    17.0 10010331 - Congenital, familial and genetic disorders 10049889 Craniosynostosis PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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