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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44358   clinical trials with a EudraCT protocol, of which   7384   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,358 result(s) found. Displaying page 1,350 of 2,218.
    «« First « Previous 1346  1347  1348  1349  1350  1351  1352  1353  1354  Next» Last»»
    EudraCT Number: 2007-003576-19 Sponsor Protocol Number: I07015 Start Date*: 2007-10-18
    Sponsor Name:CHU de LIMOGES
    Full Title: Evaluation de l'efficacité et de la tolérance du Lanreotide LP 90 mg versus placebo dans la diminution de la lyphorrhée post curage axillaire dans les cancers du sein.
    Medical condition: cancer du sein
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006187 Breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-012051-20 Sponsor Protocol Number: OXN 3505 Start Date*: 2009-08-24
    Sponsor Name:Mundipharma
    Full Title: Study of the efficacy of prolonged release oxycodone/naloxone (OXN PR), compared to prolonged release oxycodone (Oxy PR), for the reduction of the intensity of opioid-induced constipation symptoms ...
    Medical condition: For both compounds, treatment for cancer or non-cancer pain, adult subjects with a diagnosis of cancer pain or non-cancer pain such as chronic low back pain, osteoarthritis or other. Only for targi...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-006054-17 Sponsor Protocol Number: AC-055B201 Start Date*: Information not available in EudraCT
    Sponsor Name:Actelion Pharmaceuticals Ltd.
    Full Title: A double-blind, randomized, placebo-controlled, multicenter, parallel group study to evaluate the efficacy, safety, and tolerability of macitentan in patients with idiopathic pulmonary fibrosis
    Medical condition: To evaluate the efficacy, safety, and tolerabilitiy of macitentan in patients with idiopathic pulmonary fibrosis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021240 Idiopathic pulmonary fibrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) ES (Completed) SI (Completed) SE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001891-35 Sponsor Protocol Number: D4200C00080 Start Date*: 2007-06-22
    Sponsor Name:AstraZeneca SAS
    Full Title: A randomized, double-blind phase II trial to assess the efficacy and safety of bicalutamide (Casodex® ) associated to ZD6474 (Zactima™ ) or to placebo in patients with castration-refractory metasta...
    Medical condition: Metastatic prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036909 Prostate cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-001747-18 Sponsor Protocol Number: ML 21421 Start Date*: 2008-06-05
    Sponsor Name:ROCHE
    Full Title: Etude multicentrique évaluant le maintien du taux d’hémoglobine avec une administration sous-cutanée mensuelle de C.E.R.A. (activateur continu du récepteur de l’érythropoïétine) chez des patients i...
    Medical condition: Patients insuffisants rénaux chroniques sous dialyse péritonéale
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054353 Chronic renal failure anemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-006977-34 Sponsor Protocol Number: C14005 Start Date*: 2009-05-11
    Sponsor Name:Millennium Pharmaceuticals, Inc.
    Full Title: A Phase 2 Trial of MLN8237, an Oral Aurora A Kinase Inhibitor, in Adult Patients with Acute Myelogenous Leukemia and High-Grade Myelodysplastic Syndrome
    Medical condition: Acute myelogenous leukemia (AML) and high-grade myelodysplastic syndrome (MDS)
    Disease: Version SOC Term Classification Code Term Level
    11.1 10028533 LLT
    11.1 10000886 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-003165-41 Sponsor Protocol Number: ML 21273 Start Date*: 2007-08-30
    Sponsor Name:ROCHE
    Full Title: Étude prospective, multicentrique, ouverte et randomisée évaluant l’efficacité et la tolérance de Cellcept® (MMF) avec suivi thérapeutique pharmacologique, tacrolimus et épargne en corticoïdes vers...
    Medical condition: Patients transplantés hépatiques de novo
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024715 Liver transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-010114-30 Sponsor Protocol Number: D1531C00009 Start Date*: 2009-06-23
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, open-label, multi-centre, 2-stage, parallel group study to assess the efficacy, safety and tolerability of AZD1152 alone and in combination with low dose cytosine arabinoside (LDAC) i...
    Medical condition: Acute Myeloid Leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000880 Acute myeloid leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) IT (Prematurely Ended) ES (Prematurely Ended) FR (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017858-12 Sponsor Protocol Number: LEO 22811-S22 Start Date*: 2010-05-11
    Sponsor Name:LEO Pharma A/S
    Full Title: A phase 2a proof of concept study comparing three doses of an oral solution of LEO 22811 with a placebo oral solution for the treatment of psoriasis vulgaris
    Medical condition: Psoriasis vulgaris
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-011125-14 Sponsor Protocol Number: RV4104A-2008-548 Start Date*: 2009-07-06
    Sponsor Name:Pierre Fabre Dermatologie
    Full Title: A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a sequential therapy with RV4104A ointment, ciclopiroxolamine cream and ciclopirox film-forming solutio...
    Medical condition: Patients suffering from distal-lateral or lateral subungual onychomycosis of one great toenail (the target nail) without matrix involvement
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030338 Onychomycosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-013049-27 Sponsor Protocol Number: FMTO901 Start Date*: 2009-10-22
    Sponsor Name:MAYOLY-SPINDLER
    Full Title: Evaluation de l’intérêt thérapeutique de MeteoSpasmyl ® administré à la demande dans la prise en charge du syndrome de l’intestin irritable.
    Medical condition: Syndrome de l'intestin irritable
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023003 Irritable bowel syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-020224-22 Sponsor Protocol Number: PTC124-GD-011-HEM Start Date*: 2010-08-26
    Sponsor Name:PTC Therapeutics, Inc
    Full Title: A Phase 2a Study of Ataluren (PTC124) as an Oral Treatment for Nonsense-Mutation-Mediated Hemophilia A and B
    Medical condition: Nonsense-Mutation-Mediated Hemophilia A and B
    Disease: Version SOC Term Classification Code Term Level
    12.1 10060613 Hemophilia A (Factor VIII) LLT
    12.1 10060614 Hemophilia B (Factor IX) LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-008309-23 Sponsor Protocol Number: ML22017 Start Date*: 2009-04-24
    Sponsor Name:ROCHE
    Full Title: Etude clinique comparative en double aveugle versus placebo sur la rapidité d’action du tocilizumab sur le soulagement des patients atteints de polyarthrite rhumatoïde active avec réponse inadéquat...
    Medical condition: Polyarthrite rhumatoïde active modérée à sévère de moins de 10 ans d'ancienneté, avec réponse inadéquate au méthotrexate (MTX) et/ou à un autre DMARD et/ou à au moins un anti-TNF
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-006050-25 Sponsor Protocol Number: 20060362 Start Date*: 2008-05-15
    Sponsor Name:Amgen Inc.
    Full Title: An International, Randomized, Double-blind, Placebo-controlled, Phase 2 Study of AMG 479 with Exemestane or Fulvestrant in Postmenopausal Women with Hormone Receptor Positive Locally Advanced or Me...
    Medical condition: Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) FR (Completed) IE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002601-40 Sponsor Protocol Number: CD20-0703 Start Date*: 2008-09-25
    Sponsor Name:LFB BIOTECHNOLOGIES
    Full Title: Open, non-controlled, multicentre, first-in-man study using escalating doses of LFB-R603 in patients with advanced stage B-Chronic lymphocytic leukemia
    Medical condition: B-Chronic Lymphocytic Leukemia
    Disease: Version SOC Term Classification Code Term Level
    11 10008960 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-018859-97 Sponsor Protocol Number: 31-08-263 Start Date*: 2010-10-04
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc
    Full Title: A Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Patients with Major Depressive Disorder.
    Medical condition: Major Depressive Disorder (MDD)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10025454 Major depressive disorder, recurrent episode LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed) ES (Prematurely Ended) HU (Prematurely Ended) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019544-39 Sponsor Protocol Number: 20090072 Start Date*: 2010-10-04
    Sponsor Name:Amgen Inc
    Full Title: A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects with Moderate to Severe Crohn’s Disease
    Medical condition: Crohn’s disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10017947 - Gastrointestinal disorders 10011408 Crohns disease aggravated LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) NL (Prematurely Ended) ES (Prematurely Ended) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-005371-34 Sponsor Protocol Number: 2 39 00240 133 Start Date*: 2008-03-18
    Sponsor Name:BEAUFOUR IPSEN PHARMA
    Full Title: EFFICACY OF EGb 761® 120 mg bid VERSUS PLACEBO IN PATIENTS SUFFERING FROM FRIEDREICH ATAXIA A 3 months, phase II, randomised, double blind, placebo-controlled, parallel groups, clinical study.
    Medical condition: Out patient suffering from friedreich ataxia aged from 12 to 20 years
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-005564-27 Sponsor Protocol Number: CL2-20098-067 Start Date*: 2008-07-15
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effect of agomelatine (25 mg) given orally once a day for 7 days on cerebral activity measured by functional MRI during processing of emotional stimuli in patients with Major Depressive Disorder. A...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057840 Major depression LLT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-003856-32 Sponsor Protocol Number: CL3-90652-004 Start Date*: 2008-12-05
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Evaluation de l’effet de la prise orale de perindopril orodispersible à la dose de 0,150 mg/kg/jour sur la fonction musculaire et myocardique dans la dystrophie musculaire de Duchenne à un stade pr...
    Medical condition: dystrophie musculaire de Duchenne
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028354 Muscular dystrophies and other myopathies LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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