Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44393 clinical trials with a EudraCT protocol, of which 7405 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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Trials with a EudraCT protocol (44,393)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

44,393 result(s) found. Displaying page 1,526 of 2,220.

EudraCT Number: 2009-015716-18

Sponsor Protocol Number: AT08/09

Start Date*: 2009-09-18

Sponsor Name:University Hospitals Leuven

Full Title: A comparative trial between the analgesic efficacy of a standard postoperative analgesic regimen and TAP- block in addition to a standard postoperative regimen after inguinal hernia repair in a su...

Medical condition: Pain treatment after laparascopic ingiunal hernia repair.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.0		10036276	Postoperative analgesia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: BE (Completed)

Trial results: View results

EudraCT Number: 2018-002233-37

Sponsor Protocol Number: IPX203-B16-02

Start Date*: 2019-03-18

Sponsor Name:Impax Laboratories, LLC

Full Title: A randomized controlled study to compare the safety and efficacy of IPX203 with immediate-release carbidopa-levodopa in Parkinson's disease patients with motor fluctuations.

Medical condition: Parkinson's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT
	20.0	10029205 - Nervous system disorders	10029205	Nervous system disorders	SOC
	20.0	10029205 - Nervous system disorders	10028035	Movement disorder	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: CZ (Completed) DE (Completed) GB (GB - no longer in EU/EEA) PL (Completed) IT (Completed)

Trial results: View results

EudraCT Number: 2017-002468-41

Sponsor Protocol Number: Dial-1

Start Date*: 2018-06-21

Sponsor Name:University Medical Center of the Johannes Gutenberg- University Mainz

Full Title: A phase I/II multicenter, open-label Study of DKN-01 to investigate the anti-tumor activity and safety of DKN-01 in Patients with Hepatocellular Carcinoma and WNT signaling Alterations

Medical condition: Hepatocellular Carcinoma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10073071	Hepatocellular carcinoma	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended)

Trial results: View results

EudraCT Number: 2007-006125-28	Sponsor Protocol Number: AT 15/10/07	Start Date*: 2007-12-17
Sponsor Name:University Hospitals Leuven
Full Title: Comparison of intrathecal low-dose ropivacaine, bupivacaine and lidocaine for knee arthroscopy in ambulatory setting. a randomised, double-blind trial;
Medical condition: Male and female patients, scheduled for an elective knee arthroscopy.
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: BE (Completed)
Trial results: View results

EudraCT Number: 2018-000415-25

Sponsor Protocol Number: PROSPER

Start Date*: 2018-08-10

Sponsor Name:University Hospital Heidelberg

Full Title: PANCREATIC RESECTION WITH PERIOPERATIVE OFF-LABEL STUDY OF PROPRANOLOL AND ETODOLAC – A PHASE II RANDOMIZED TRIAL

Medical condition: Patients with pancreatic carcinoma treated by pancreatoduodenectomy.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004865	10033659	Pancreatoduodenectomy	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended)

Trial results: View results

EudraCT Number: 2017-000456-26

Sponsor Protocol Number: Tumorspheres_Colrec

Start Date*: 2017-07-10

Sponsor Name:Vejle Hospital

Full Title: Predictive value of in-vitro testing anti-cancer therapy sensitivity on tumorspheres from patients with metastatic colorectal cancer

Medical condition:

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004864	10052362	Metastatic colorectal cancer	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DK (Completed)

Trial results: View results

EudraCT Number: 2016-002956-25

Sponsor Protocol Number: MAS-OLE-16-003

Start Date*: 2016-11-18

Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE

Full Title: Olevia for the prevention of atrial fibrillation post heart valve-surgery.

Medical condition: POST-OPERATIVE ATRIAL FIBRILLATION

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004849	10016566	Fibrillation atrial	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: View results

EudraCT Number: 2017-000589-31

Sponsor Protocol Number: NEMESIS

Start Date*: 2018-02-02

Sponsor Name:SOCIETà CAMPANA DI IMMUNOTERAPIA ONCOLOGICA

Full Title: multi stage phase II trial of Nivolumab (an anti –PD-1) in patients with platinum resistant Mismatch Repair deficient germinal cells tumours

Medical condition: patients with platinum resistant Mismatch Repair deficient germinal cells tumours

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10061184	Germ cell cancer	PT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10061184	Germ cell cancer	PT

Population Age: Adults, Elderly

Gender: Male

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2015-005090-20

Sponsor Protocol Number: FADOI.01.2016

Start Date*: 2018-05-17

Sponsor Name:FONDAZIONE FADOI

Full Title: Rivaroxaban or placebo for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer: a randomized, double blind, placebo-controlled study. THE PRO-LAPS STUDY II

Medical condition: Prevention of venous thromboembolism after laparoscopic surgery for colorectal cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	100000004865	10067650	Pulmonary embolism prophylaxis	LLT
	21.1	100000004865	10012108	Deep venous thrombosis prophylaxis	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2018-003542-17

Sponsor Protocol Number: FISM_IRON-MDS

Start Date*: 2019-05-06

Sponsor Name:FONDAZIONE ITALIANA SINDROMI MIELODISPLASTICHE ETS

Full Title: Early and low dose Deferasirox (3.5 mg/kg FCT) to suppress NTBI and LPI as early intervention to prevent tissue iron overload in lower risk MDS

Medical condition: Adult patients with low risk MDS

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004864	10028532	Myelodysplasia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2018-001741-14

Sponsor Protocol Number: TEM-MM-101

Start Date*: 2018-12-13

Sponsor Name:OSPEDALE SAN RAFFAELE

Full Title: A phase I/II dose escalation study evaluating safety and activity of autologous CD34+-enriched hematopoietic progenitor cells genetically modified with a lentiviral vector encoding for the human in...

Medical condition: Multiple myeloma in early relapse after intensive front line therapy

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004864	10028228	Multiple myeloma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: View results

EudraCT Number: 2020-005343-23

Sponsor Protocol Number: ADAIDO

Start Date*: 2021-05-28

Sponsor Name:IRCCS ISTITUTO ORTOPEDICO GALEAZZI S.P.A

Full Title: Effect of the antiresorptive treatment with alendronate versus no treatment after denosumab and aromatase inhibitors discontinuation in low fracture risk osteopenic postmenopausal women with non me...

Medical condition: post-menopausal osteoporosis in women with non-metastatic hormonal receptor positive (HR+) breast cancer.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10028395 - Musculoskeletal and connective tissue disorders	10049088	Osteopenia	PT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2012-003729-62

Sponsor Protocol Number: R-Verapamil-001

Start Date*: 2013-01-16

Sponsor Name:CENTER LABORATORIES, INC

Full Title: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of R-Verapamil in the Prophylaxis of Episodic Cluster Headache

Medical condition: Episodic Cluster Headache

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	15.0	10029205 - Nervous system disorders	10059133	Cluster headache	PT

Population Age: Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2020-002533-14

Sponsor Protocol Number: REVERT

Start Date*: 2021-02-15

Sponsor Name:DIP. MEDICINA DEI SISTEMI UNIVERSITà DEGLI STUDI DI ROMA TOR VERGATA

Full Title: REVERT – taRgeted thErapy for adVanced colorEctal canceR paTients.

Medical condition: unresectable metastatic colorectal cancer (mCRC)

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10052358	Colorectal cancer metastatic	PT
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10052358	Colorectal cancer metastatic	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2018-002948-88

Sponsor Protocol Number: CRETA

Start Date*: 2019-02-20

Sponsor Name:ALMA MATER STUDIORUM UNIVERSITà DI BOLOGNA

Full Title: Phase II study to evaluate the activity and safety of Cabozantinib in pretreated, advanced RET-reArranged non-small cell lung cancer patients: CRETA trial

Medical condition: Advanced RET-rearranged non-small cell lung cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004864	10064049	Lung adenocarcinoma metastatic	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2015-001767-40

Sponsor Protocol Number: AZALEA704

Start Date*: 2016-11-10

Sponsor Name:AZIENDA OSPEDALIERA "OSPEDALI RIUNITI MARCHE NORD"

Full Title: A phase II study testing the efficacy of combined azacitidine and lenalidomide for non-M3 acute myeloid leukemia (AML) patients aged between 60 and 70 years, fit, relapsed or refractory: the AZALEA...

Medical condition: ACUTE MYELOID LEUKEMIA

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004864	10024289	Leukaemia acute	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2017-002340-32

Sponsor Protocol Number: APIDULCIS

Start Date*: 2019-03-19

Sponsor Name:FONDAZIONE ARIANNA ANTICOAGULAZIONE

Full Title: APIDULCIS: Extended anticoagulation with low-dose apixaban after a standard course anticoagulation in patients with a first venous thromboembolism who have positive d-dimer

Medical condition: a first episode of proximal deep vein thrombosis (DVT) and/or pulmonary embolism (PE)

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.0	10038738 - Respiratory, thoracic and mediastinal disorders	10037377	Pulmonary embolism	PT
	21.1	10047065 - Vascular disorders	10051055	Deep vein thrombosis	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2015-001868-19

Sponsor Protocol Number: 2015-001

Start Date*: 2015-10-15

Sponsor Name:University medical center of Johannes Gutenberg University Mainz

Full Title: A randomized, double-blind, placebo-controlled, mono-center study to evaluate the effects of mepolizumab on airway physiology in patients with eosinophilic asthma: the MEMORY study

Medical condition: severe eosinophilic asthma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.1	100000004855	10068462	Eosinophilic asthma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended)

Trial results: View results

EudraCT Number: 2016-000284-17	Sponsor Protocol Number: VinoMetro2015-007	Start Date*: 2016-11-11
Sponsor Name:Universitätsmedizin Mainz
Full Title: Phase II study of metronomic treatment with daily oral vinorelbine as first-line chemotherapy in patients with advanced/metastatic HR+/HER2- breast cancer resistant to endocrine therapy (VinoMetro).
Medical condition: HR+/HER2- advanced/metastatic breast cancer
Disease:
Population Age: Adults, Elderly		Gender: Female
Trial protocol: DE (Prematurely Ended)
Trial results: View results

EudraCT Number: 2013-005364-26	Sponsor Protocol Number: RE-LATED-AF	Start Date*: 2014-07-17
Sponsor Name:University Medical Center of the Johannes Gutenberg University Mainz
Full Title: Resolution of Left Atrial-Appendage Thrombus – Effects of Dabigatran in patients with AF (RE-LATED AF) – A Prospective, multicenter, randomized, open-label, controlled, explorative, blinded-endpoin...
Medical condition: Left atrial-appendage thrombus in atrial fibrillation
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: DE (Prematurely Ended)
Trial results: View results

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The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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