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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,394 result(s) found. Displaying page 1,538 of 2,220.
    «« First « Previous 1534  1535  1536  1537  1538  1539  1540  1541  1542  Next» Last»»
    EudraCT Number: 2012-002647-18 Sponsor Protocol Number: IFCT-1102 Start Date*: 2017-10-13
    Sponsor Name:IFCT
    Full Title: phase II study evaluating the interest of the re-introduction of pemetrexed and platinum (cisplatin or carboplatin) with prolonged angiogenic blocking by bevacizumab in non squamous non small cell ...
    Medical condition: Advanced stage non squamous non small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025062 Lung cancer stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-001397-41 Sponsor Protocol Number: ASPIRIN_version1.0_Belgium Start Date*: 2017-07-31
    Sponsor Name:Antwerp University Hospital
    Full Title: A Phase III double-blind placebo-controlled Randomised Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients
    Medical condition: Patients with resected colon carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-002291-27 Sponsor Protocol Number: RIVAR-CTP-01 Start Date*: 2016-11-07
    Sponsor Name:Aalborg University Hospital
    Full Title: Randomized trial of aspirin versus rivaroxaban after replacement of the aortic valve with a biological valve prosthesis
    Medical condition: Aortic valve stenosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004525-41 Sponsor Protocol Number: 14VR4 Start Date*: 2015-04-10
    Sponsor Name:Versartis, Inc.
    Full Title: Comparison of Somavaratan (VRS-317), a Long-acting Human Growth Hormone, to Daily rhGH in a Phase 3, Randomized, One-year, Open-label, Multi-center, Non-inferiority Trial in Pre-pubertal Children w...
    Medical condition: Growth hormone deficiency
    Disease: Version SOC Term Classification Code Term Level
    19.0 10014698 - Endocrine disorders 10056438 Growth hormone deficiency PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed) BE (Completed) NL (Ongoing) PL (Completed)
    Trial results: View results
    EudraCT Number: 2011-005684-24 Sponsor Protocol Number: CME-LEM2 Start Date*: 2014-01-16
    Sponsor Name:Fundación Investigación Biomédica Hospital Universitario Puerta de Hierro
    Full Title: Subarachnoid administration of autologous bone marrow stromal cells in incomplete spinal cord injury.
    Medical condition: Incomplete spinal cord injury, due to traumatical or ischemic cause.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10041545 Spinal cord and nerve root disorders traumatic HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-001775-37 Sponsor Protocol Number: MDGH-MOX-2001 Start Date*: 2019-09-20
    Sponsor Name:Medicines Development Limited (trading as Medicines Development for Global Health)
    Full Title: A Phase II, randomized, double-blind, parallel group dose finding study of single oral doses of moxidectin in adults with scabies
    Medical condition: Scabies (infection with Sarcoptes scabiei)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10039511 Scabies LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-001040-23 Sponsor Protocol Number: TranspoCART19 Start Date*: 2023-03-15
    Sponsor Name:Instituto de Investigación Biomédica de Salamanca (IBSAL) - IECSCYL
    Full Title: Phase I/IIa multicentre phase I/IIa study of infusion of autologous peripheral blood T lymphocytes expanded and genetically modified using Sleeping Beauty family transposons to express a chimeric a...
    Medical condition: Relapsed or refractory B-cell lymphoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10003900 B-cell lymphomas NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000437-32 Sponsor Protocol Number: MK-8591-011 Start Date*: 2017-12-18
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 2B, Randomized, Double-Blind, Active-Comparator-Controlled, Dose- Ranging Clinical Trial to Evaluate the Safety, Tolerability, Antiretroviral Activity, and Pharmacokinetics of MK-8591 Given...
    Medical condition: HIV-1 infection
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-002110-42 Sponsor Protocol Number: PHRCIR2015DAPOIGNY Start Date*: 2017-10-18
    Sponsor Name:CHU CLERMONT-FERRAND
    Full Title: Evaluation of the effectiveness and safety of ethosuximide in the treatment of abdominal pain associated with irritable bowel syndrome
    Medical condition: abdominal pain related to irritable bowel syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003702-42 Sponsor Protocol Number: B7981058 Start Date*: 2022-05-17
    Sponsor Name:Pfizer Inc.
    Full Title: AN INTERVENTIONAL PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL GROUP STUDY OF THE EFFICACY AND SAFETY OF RITLECITINIB (PF-06651600) IN ADULT PARTICIPANTS WITH MODERATELY TO SEVER...
    Medical condition: Moderate to Severe Ulcerative Colitis (UC)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002546-49 Sponsor Protocol Number: SCP-01-001 Start Date*: 2014-10-03
    Sponsor Name:scPharmaceuticals Inc
    Full Title: A single center, randomized, open-label, cross-over exploratory study to evaluate the pharmacodynamic and pharmacokinetic response to a subcutaneous administration or oral administration of furosem...
    Medical condition: Fluid overload in heart failure
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-000538-31 Sponsor Protocol Number: Neuroimpa2015 Start Date*: 2015-06-01
    Sponsor Name:Charité University medicine Berlin
    Full Title: NEUORIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the knee joint
    Medical condition: chronic arthritis of the knee joint effusion as part of spondyloarthritis (Assessments in SpondyloArthritis international Society, ASAS criteria), Rheumatoid Arthritis, RA (according to American Co...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10067624 Knee arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-002963-31 Sponsor Protocol Number: D-CN-52014-243 Start Date*: 2023-01-13
    Sponsor Name:Ipsen Pharma
    Full Title: AN OPEN-LABEL, MULTICENTRE, SINGLE-ARM STUDY TO ASSESS THE EFFICACY AND SAFETY OF TRIPTORELIN 3-MONTH FORMULATION IN CHINESE CHILDREN WITH CENTRAL PRECOCIOUS PUBERTY
    Medical condition: Central Precocious Puberty
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-000846-35 Sponsor Protocol Number: EFG100161 Start Date*: 2005-09-07
    Sponsor Name:GlaxoSmithKline
    Full Title: GlaxoSmithKline Study EGF100161 – An open-label, multicenter, 2 Part, Phase I/II dose escalation study of oral lapatinib in combination with docetaxel (Taxotere) plus trastuzumab (Herceptin) in sub...
    Medical condition: Metastatic Breast Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003955-23 Sponsor Protocol Number: DR2 Start Date*: 2016-04-15
    Sponsor Name:Dept. of Ophthalmology, Rigshospitalet – Glostrup
    Full Title: Diabetic retinopathy: Effects of melatonin treatment on visual functions and circadian rhythm.
    Medical condition: Diabetic Retinopathy and Sleep disorder
    Disease: Version SOC Term Classification Code Term Level
    20.1 10015919 - Eye disorders 10012689 Diabetic retinopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-003887-39 Sponsor Protocol Number: P1200_46 Start Date*: 2020-10-29
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: Molecular effects of Apremilast (Otezal) in synovial biopsies of patients with psoriatic arthisis
    Medical condition: Psoriasis and Psoriatic Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005928-17 Sponsor Protocol Number: FTB-11-ITRA01 Start Date*: 2012-04-26
    Sponsor Name:Katholieke Universiteit Leuven - Pharmacotechnology and Biopharmacy
    Full Title: Gastrointestinal behavior of itraconazole in healthy volunteers
    Medical condition: healthy volunteers (administration of antifungal drug)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002479-28 Sponsor Protocol Number: MOL-ARDS-002 Start Date*: 2015-09-24
    Sponsor Name:Justus-Liebig University
    Full Title: GM-CSF Inhalation to improve HOst defense and Pulmonary barrier rEstoration
    Medical condition: Pneumonia associated Acute Respiratory Distress Syndrome (ARDS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10000036 A.R.D.S. LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001849-26 Sponsor Protocol Number: DCX-AIO-CHARITE Start Date*: 2008-09-18
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Multicentre, open phase II trial to evaluate safety and efficacy of a perioperative chemotherapy with docetaxel, cisplatin and capecitabin in patients suffering from adenocarcinoma of the stomach, ...
    Medical condition: Gastric cancer is the second most frequent cause of cancer-related deaths worldwide. In 2002 934,000 gastric carcinomas were diagnosed and 700,000 deaths related to this disease were reported. The ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-003498-23 Sponsor Protocol Number: SPLENTIR-01/RESCUE Start Date*: 2020-12-18
    Sponsor Name:Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
    Full Title: A multicentre, double-blind, randomized clinical trial for the effectiveness of an analgesic which contains the combination of acetylsalicylic acid-paracetamol and caffeine (400 + 200 + 50 mg / ...
    Medical condition: The aim of the study was to compare the efficacy of an analgesic containing a combination of acetylsalicylic acid, paracetamol and caffeine (SPLENTIR (400 + 200 + 50 mg / tab)) with placebo for the...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10027605 Migraine NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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