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Clinical trials for Post-Operative Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    402 result(s) found for: Post-Operative Pain. Displaying page 16 of 21.
    EudraCT Number: 2010-018450-12 Sponsor Protocol Number: 706079098 Start Date*: 2010-08-18
    Sponsor Name:Agneta Blanck Olerup
    Full Title: Optimising pain control after caesarean section - an evaluation if oxycodone can replace morphine and low potency opioids postoperatively.
    Medical condition: Pain management after elective cesarean section.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036276 Postoperative analgesia LLT
    Population Age: Newborns, Under 18, Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001054-22 Sponsor Protocol Number: OPMICS-1 Start Date*: 2020-09-21
    Sponsor Name:Claus Anders Bertelsen
    Full Title: Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block in Minimally Invasive Colon Surgery: A Randomized Controlled Multicentre Clinical Trial
    Medical condition: Colon cancer patients undergoing elective minimally invasive colon surgery and receiving a transversus abdominis plane block for postoperative pain management. Ropivacaine is used as the local anal...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000680-24 Sponsor Protocol Number: POSTrct_ORTGH Start Date*: 2012-05-25
    Sponsor Name:Academisch Medisch Centrum
    Full Title: Pain management after operative treatment of extremity fractures, a randomized clinical trial
    Medical condition: Patient satisfaction with pain relief and pain intensity (Numeric Rating Scale) will be investigated. Also to find predictors we will investigate: age, sex, trauma-site, fracture type, AIS score, ...
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004859 10024956 Lower limb fractures HLT
    19.1 100000004865 10036236 Postoperative pain relief LLT
    19.1 100000004848 10033762 Paracetamol LLT
    17.1 100000004859 10046292 Upper limb fractures HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-003010-26 Sponsor Protocol Number: B076201627677 Start Date*: 2018-01-11
    Sponsor Name:Centre Hospitalier Universitaire Saint Pierre , ULB
    Full Title: Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia: a Randomised and Controlled Clinical Trial
    Medical condition: Parturients undergoing an elective caesarean section performed under spinal anaesthesia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-001715-36 Sponsor Protocol Number: TZP-101-CL-P005 Start Date*: 2007-07-05
    Sponsor Name:Tranzyme, Inc
    Full Title: A Multicenter, Randomised, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Assess the Efficacy and Safety of TZP-101 when Administered as a 30 Minute IV Infusion for Postoperative Ileus to ...
    Medical condition: Post Operative Ileus (POI) in subjects undergoing major open abdominal surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054048 Postoperative ileus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021924-81 Sponsor Protocol Number: AC/10/01 Start Date*: 2010-10-18
    Sponsor Name:Hospital General de Granollers
    Full Title: Eficacia Analgésica del Transversus Abdomini Plane (TAP) Block en cirugía de Cesárea
    Medical condition: transversus abdomini plane block en cirurgía de cesárea
    Disease: Version SOC Term Classification Code Term Level
    13 10036272 Analgesia postquirúrgica LLT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011492-73 Sponsor Protocol Number: 13.09 Start Date*: 2009-09-28
    Sponsor Name:Swindon and Marlborough NHS Foundation Trust
    Full Title: Analysis of Blood Loss With the Use of Fibrin Sealant in Total Knee Replacement Surgery – A Randomised Controlled Study
    Medical condition: Blood loss in total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-017804-95 Sponsor Protocol Number: ATRHEMOS/1 Start Date*: 2010-03-05
    Sponsor Name:Fundació Institut de Recerca de l?Hospital de la Santa Creu i Sant Pau
    Full Title: Prevención del sangrado postoperatorio: Ensayo clínico unicéntrico, aleatorizado, paralelo y controlado que evalúa la eficacia de la cola de fibrina y el ácido tranexámico en pacientes intervenidos...
    Medical condition: Pacientes que precisan de una artroplastia de rodilla. Patients with are needed of an arthroplasty of the knee.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000333-10 Sponsor Protocol Number: GEN/231/51/BMcK/JCL Start Date*: 2004-12-15
    Sponsor Name:Research & Innovation Services, University of Dundee
    Full Title: The inhibitory effect of local anaesthetics on the G-protein-mediated vascular flare response to bradykinin and substance P
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000647-27 Sponsor Protocol Number: CHU-930106 Start Date*: 2012-03-23
    Sponsor Name:Association hospitalière CHU BRUGMANN
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10054799 Perioperative analgesia PT
    14.1 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005534-19 Sponsor Protocol Number: FRIA_FATSURG_1 Start Date*: 2012-01-31
    Sponsor Name:Vrije Universiteit Brussel
    Full Title: The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients: a double blinded randomized placebo-controlled trial.
    Medical condition: Post-operative muscle weakness, fatigue and inflammation.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-005146-30 Sponsor Protocol Number: 916-17 Start Date*: 2018-11-05
    Sponsor Name:Sahlgrenska universitetssjukhuset
    Full Title: See below
    Medical condition: See below
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000087-26 Sponsor Protocol Number: 2019/09 Start Date*: 2020-04-16
    Sponsor Name:CMC AMBROISE PARE
    Full Title: Time to transit Recovery After treatment with Naloxegol in cardiac Surgery Intensive care Trial
    Medical condition: ileus after cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    20.1 100000004863 10051798 Postoperative constipation LLT
    20.0 100000004856 10071128 Opioid induced constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-001630-18 Sponsor Protocol Number: CWL15001 Start Date*: 2023-09-20
    Sponsor Name:5med GmbH
    Full Title: A randomized, parallel group, multi-center study of a fentanyl nasal spray compared with placebo nasal spray for postoperative pain management and prolonged open treatment over up to 120 hours post...
    Medical condition: Management of pain following orthopedic surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) BG (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-003656-11 Sponsor Protocol Number: A0081171 Start Date*: 2007-11-26
    Sponsor Name:Pfizer, S.A
    Full Title: ESTUDIO ALEATORIZADO, DOBLE CIEGO, MULTICÉNTRICO, DE DETERMINACIÓN DE DOSIS PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE PREGABALINA EN COMPARACIÓN CON PLACEBO COMO TRATAMIENTO COMPLEMENTARIO DEL DOL...
    Medical condition: DOLOR POSTOPERATORIO POST SURGICAL PAIN
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Completed) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000707-28 Sponsor Protocol Number: FODANKEL01 Start Date*: 2014-07-04
    Sponsor Name:Aarhus University Hospital
    Full Title: Displacement of popliteal sciatic nerve catheters after major foot and ankle surgery. Long axis (LAX) compared with short axis (SAX), a MR/US image fusion study
    Medical condition: The medical condition to be examined in this study, is postoperative pain after major foot and ankle surgery. Which way to insert a sciatic nerve catheter to treat postoperative pain is the most ef...
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10036236 Postoperative pain relief LLT
    17.0 100000004865 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-016088-13 Sponsor Protocol Number: Kirkipu 09-1 Start Date*: 2009-12-31
    Sponsor Name:Kirurgisen sairaalan munuaisensiirtoihin liittyvän kivun hoidon tutkimusryhmä
    Full Title: Pregabaliinin vaikutus leikkauskipuun ja toipumiseen munuaisensiirtopotilailla
    Medical condition: Patients who receive kidney transplant
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023438 Kidney transplant LLT
    12.0 10054711 Postoperative pain LLT
    12.0 10054048 Postoperative ileus LLT
    12.0 10028818 Nausea postoperative LLT
    12.0 10061243 Post procedural nausea LLT
    12.0 10036238 Postoperative vomiting LLT
    12.0 10047707 Vomiting postoperative LLT
    12.0 10039897 Sedation LLT
    12.0 10040760 Situational anxiety LLT
    12.0 10002855 Anxiety LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001725-27 Sponsor Protocol Number: KKSH152 Start Date*: 2019-10-24
    Sponsor Name:Martin-Luther-Universität Halle-Wittenberg
    Full Title: A randomized, open, three-arm comparative study of modern methods of postoperative pain therapy in patients with knee endoprostheses.
    Medical condition: Postoperative pain therapy after implantation of a knee endoprosthesis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-005773-21 Sponsor Protocol Number: IBMS-SPB Start Date*: 2016-05-10
    Sponsor Name:INSTITUTO DE INVESTIGACIÓN SANITARIA LA FE
    Full Title: Impact of the serratus plane block in pain and the use of opioids in breast surgery
    Medical condition: Patients undergoing oncological surgery and/or breast reconstruction surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-004545-32 Sponsor Protocol Number: DEX-TRA-04 Start Date*: 2013-02-27
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: A randomized, double-blind, placebo and active-controlled, parallel-group study to evaluate the analgesic efficacy and safety of dexketoprofen trometamol and tramadol hydrochloride oral fixed combi...
    Medical condition: Treatment of moderate to severe acute pain following abdominal hysterectomy
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SK (Completed) HU (Completed) ES (Completed) LV (Completed) PL (Completed) LT (Completed) RO (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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