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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44399   clinical trials with a EudraCT protocol, of which   7411   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,399 result(s) found. Displaying page 1,759 of 2,220.
    «« First « Previous 1755  1756  1757  1758  1759  1760  1761  1762  1763  Next» Last»»
    EudraCT Number: 2022-002407-37 Sponsor Protocol Number: BET-PSMA-121 Start Date*: 2023-05-22
    Sponsor Name:Blue Earth Therapeutics Limited
    Full Title: An open-label, multicentre, integrated Phase 1 & 2 study to evaluate the safety, tolerability, radiation dosimetry and anti-tumour activity of Lutetium (177Lu) rhPSMA-10.1 injection in men with met...
    Medical condition: PSMA-positive metastatic castration-resistant prostate cancer (mCRPC)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10076506 Castration-resistant prostate cancer LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-002047-29 Sponsor Protocol Number: PI843_843_0080 Start Date*: 2021-07-29
    Sponsor Name:CHU Amiens Picardie
    Full Title: Comparison of azathioprine to methotrexate in combination therapy with adalimumab in Crohn’s Disease: an open-label randomized controlled trial
    Medical condition: crohn disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-001514-18 Sponsor Protocol Number: Cypher-TX_Pilot Start Date*: 2022-09-12
    Sponsor Name:University Medical Center Ljubljana
    Full Title: Cytomegalovirus Prophylaxis with Letermovir in Heart Transplant Recipients: A Non-randomized Cohort Pilot Study
    Medical condition: The focus of investigation in the proposed study protocol is the rates of Cytomegalovirus viremia and/or disease in patients after heart transplantation undergoing novel CMV prophylaxis protocol us...
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: SI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-004165-20 Sponsor Protocol Number: AITIK Start Date*: 2023-04-26
    Sponsor Name:CHU de Poitiers
    Full Title: Discontinuation of Tyrosine Kinase Inhibitors in chronic myeloid leukemia and impact on the immune system: a randomized controlled trial of two therapeutic strategies
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10009015 Chronic myeloid leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-000597-29 Sponsor Protocol Number: LTS13619 Start Date*: 2015-09-30
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: An Open-Label Study to Determine the Long-Term Safety, Tolerability and Biological Activity of UshStat® in Patients with Usher Syndrome type 1B
    Medical condition: Usher syndrome type 1B
    Disease: Version SOC Term Classification Code Term Level
    18.1 10010331 - Congenital, familial and genetic disorders 10063396 Usher's syndrome PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-000217-35 Sponsor Protocol Number: EpSSG RMS 2005 Start Date*: Information not available in EudraCT
    Sponsor Name:Rikshospitalet-Radiumhospitalet HF
    Full Title: EpSSG RMS 2005 a protocol for non metastatic rhabdomyosarcoma
    Medical condition: Rhabdomyosarkom (RMS) er en kreftform utgående fra muskelvev. RMS kan oppstå hvor som helst i kroppen og rammer folk i alle aldre. Behandlingen av RMS består av cellegift, operasjon og/eller strål...
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NO (Ongoing) NL (Completed) BE (Completed) IT (Ongoing) GB (GB - no longer in EU/EEA) IE (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001732-38 Sponsor Protocol Number: 1502 Start Date*: 2015-09-14
    Sponsor Name:CENTRE OSCAR LAMBRET
    Full Title: EVALUATION OF SENTINEL NODE (SN) POLICY IN EARLY STAGE ENDOMETRIAL CARCINOMAS AT INTERMEDIATE AND HIGH RISK OF RECURRENCE: RANDOMIZED STUDY COMPARING SENTINEL NODE POLICY TO CURRENT FRENCH INITIAL ...
    Medical condition: Intermediate-risk endometrioïd carcinomas : IAg3, IB(II)g1-2 High-risk endometrioïd carcinomas : IB-II g3 High-risk non endometrioïd carcinomas : I-II
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014733 Endometrial cancer PT
    Population Age: Elderly Gender: Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-003600-41 Sponsor Protocol Number: APHP200042 Start Date*: 2022-01-25
    Sponsor Name:Assistance Publique – Hôpitaux de Paris (AP-HP)
    Full Title: AMIloride for the treatment of Nephrogenic Diabetes insipidus for patients with bipolar disorder treated with lithium: a randomized controlled trial
    Medical condition: NA
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002686-15 Sponsor Protocol Number: CHUBX2021/25 Start Date*: 2022-10-18
    Sponsor Name:CHU de Bordeaux
    Full Title: Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on postintubation Morbidity: A cluster randomized controlled trial
    Medical condition: respiratory distress
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-001813-35 Sponsor Protocol Number: 2020/65 Start Date*: 2022-04-21
    Sponsor Name:Centre Antoine Lacassagne
    Full Title: AGORA-1 /ALFA 2100 study : A Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults with FLT3-ITD relapse/refractory (R/R) AML
    Medical condition: Adult patients (aged 18 years old or more) with a newly diagnosis of relapsed/refractory (R/R) AML associated to the presence a FLT3 gene internal tandem duplication (FLT3-ITD).
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10001941 AML LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-004038-12 Sponsor Protocol Number: 19-01 Start Date*: 2021-12-10
    Sponsor Name:CENTRE HOSPITALIER ANNECY GENEVOIS
    Full Title: Randomized open-label controlled trial evaluating a single-dose intravenous Dalbavancin versus standard antibiotic therapy during catheter-related bloodstream infections due to Staphylococcus aureus
    Medical condition: Staphylococcus aureus catheter bloodstream infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003121-29 Sponsor Protocol Number: D20180102 Start Date*: 2020-03-04
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes
    Medical condition: Vascular calcification and type 1 diabetes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-003627-38 Sponsor Protocol Number: CD-2019/02 Start Date*: 2019-11-12
    Sponsor Name:Centre Georges-François Leclerc
    Full Title: 18F-Fluorocholine (FCH) versus 18F-Fluorodesoxyglucose (FDG) PET/CT for the detection of lesions in patients with multiple myeloma
    Medical condition: Patient with multiple myeloma, addressed for initial evaluation and eligible for an autograft of Hematopoietic Stem Cells.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003560-31 Sponsor Protocol Number: UKM18_0021 Start Date*: 2020-01-29
    Sponsor Name:Universitätsklinikum Münster
    Full Title: A prospective multicenter phase 2 study of copanlisib in combination with rituximab and CHOP chemotherapy (COPA-R-CHOP) in patients with previously untreated diffuse large B-cell lymphoma (DLBCL)
    Medical condition: diffuse large B-cell lymphoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10012818 Diffuse large B-cell lymphoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004744-22 Sponsor Protocol Number: GERICO11/PACS10 Start Date*: 2013-05-27
    Sponsor Name:UNICANCER
    Full Title: Adjuvant systemic treatment for oestrogen-receptor (ER)-positive HER2-negative breast carcinoma in women over 70 according to Genomic Grade (GG): chemotherapy + endocrine treatment versus endocrine...
    Medical condition: oestrogen-receptor (ER)-positive HER2-negative breast carcinoma in women over 70
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    Population Age: Elderly Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-000784-23 Sponsor Protocol Number: KKS-276 Start Date*: 2020-11-17
    Sponsor Name:Philipps-Universität Marburg
    Full Title: The effects of esketamine and treatment expectation in acute major depressive disorder: a pharmacological fMRI-study (Expect)
    Medical condition: To unravel the neural correlates of the interaction between positive expectation (high/low) and single dose antidepressant treatment (verum/placebo) with esketamine in patients with major depressiv...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10037175 Psychiatric disorders SOC
    21.1 10037175 - Psychiatric disorders 10081270 Major depressive disorder LLT
    21.1 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000561-20 Sponsor Protocol Number: 020186 Start Date*: 2020-02-28
    Sponsor Name:Tampere University Hospital
    Full Title: Monitoring of neuromuscular blockade during general anaesthesia after reversal with neostigmine
    Medical condition: We are studying reappearence of nondepolarizing neuromuscular block after it has been antagonized with a combination of neostigmine and glycopyrrolate. We are trying to find the incidence of the ph...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-006710-23 Sponsor Protocol Number: Systher_1 Start Date*: 2009-10-02
    Sponsor Name:Blood Transfusion Centre of Slovenia
    Full Title: Modulation of the immune response in patients with pancreatic tubular carcinoma
    Medical condition: Pancreatic adenocarcinoma; after R0 or R1 resection and adjuvant gemcitabine treatment.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052747 Adenocarcinoma pancreas LLT
    9.1 10065908 Cystadenocarcinoma pancreas LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000300-16 Sponsor Protocol Number: P170923J Start Date*: Information not available in EudraCT
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
    Full Title: NA
    Medical condition: NA
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10078075 Gender dysphoria PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-000188-38 Sponsor Protocol Number: BUS-P3-02 Start Date*: 2023-02-21
    Sponsor Name:Bellus Health, Inc.
    Full Title: A Phase 3, 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm Efficacy and Safety Study with Open-label Extension of BLU-5937 in Adult Participants with Refractory Chronic Cough In...
    Medical condition: Refractory or Unexplained Chronic Cough
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned) SK (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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